Chapter 3 Vitamin C Alimentation via SLC Solute Carriers

Although mortality rates from pneumonia and sepsis are decreasing in many parts of the world, the incidence of these conditions continues to rise, likely due to an increasingly ageing population. Case reports and observational studies indicate a strong association between vitamin C status and infect...
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Autor*in:	Nydegger, Damien [verfasserIn] Gyimesi, Gergely Hediger, Matthias

Format:	E-Book
Sprache:	Englisch

Erschienen:	Erscheinungsort nicht ermittelbar: Taylor & Francis ; 2020

Rechteinformationen:	Open Access Creative Commons ; https://creativecommons.org/licenses/by-nc-nd/4.0

Schlagwörter:	Pharmacology Molecular biology Biology, life sciences

Umfang:	1 Online-Ressource (18 p.)

Links:	Link aufrufen Link aufrufen Link aufrufen

Katalog-ID:	1836447515

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520			\|a Although mortality rates from pneumonia and sepsis are decreasing in many parts of the world, the incidence of these conditions continues to rise, likely due to an increasingly ageing population. Case reports and observational studies indicate a strong association between vitamin C status and infectious conditions, with vitamin C deficiency predisposing individuals to infections, and conversely, infections precipitating a diminished vitamin C status. The requirements for vitamin C increase with the severity of the infectious condition, with gram amounts required to normalize the vitamin C status of critically ill patients. Over the past few years, there has been renewed interest in the role that vitamin C may play in severe infectious conditions. Vitamin C has a plethora of physiological effects, primarily due to its activity as a cofactor for a growing group of biosynthetic and regulatory enzymes, with the potential to regulate thousands of genes and cell signaling pathways. Small intervention studies have indicated that administration of gram doses of vitamin C to patients with pneumonia and sepsis improves organ function and potentially decreases mortality, although this remains to be confirmed in larger trials. The long-term quality of life outcomes of these patients also remains to be determined
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Indexfelder

author_variant	d n dn
matchkey_str	nydeggerdamiengyimesigergelyhedigermatth:2020----:hpe3iaiclmnainisco
oclc_num	1286318426
hierarchy_sort_str	2020
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allfields	(DE-627)1836447515 (DE-599)KEP062186205 (OCoLC)1286318426 (OAPEN)40106 (EBP)062186205 DE-627 eng DE-627 rda eng MMG bicssc PSD bicssc PS bicssc MKG bicssc Nydegger, Damien verfasserin aut Chapter 3 Vitamin C Alimentation via SLC Solute Carriers [Erscheinungsort nicht ermittelbar] Taylor & Francis 2020 1 Online-Ressource (18 p.) Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Open Access Unrestricted online access star Although mortality rates from pneumonia and sepsis are decreasing in many parts of the world, the incidence of these conditions continues to rise, likely due to an increasingly ageing population. Case reports and observational studies indicate a strong association between vitamin C status and infectious conditions, with vitamin C deficiency predisposing individuals to infections, and conversely, infections precipitating a diminished vitamin C status. The requirements for vitamin C increase with the severity of the infectious condition, with gram amounts required to normalize the vitamin C status of critically ill patients. Over the past few years, there has been renewed interest in the role that vitamin C may play in severe infectious conditions. Vitamin C has a plethora of physiological effects, primarily due to its activity as a cofactor for a growing group of biosynthetic and regulatory enzymes, with the potential to regulate thousands of genes and cell signaling pathways. Small intervention studies have indicated that administration of gram doses of vitamin C to patients with pneumonia and sepsis improves organ function and potentially decreases mortality, although this remains to be confirmed in larger trials. The long-term quality of life outcomes of these patients also remains to be determined Creative Commons https://creativecommons.org/licenses/by-nc-nd/4.0 cc English Pharmacology Molecular biology Biology, life sciences Gyimesi, Gergely oth Hediger, Matthias oth https://library.oapen.org/bitstream/id/13c0ef0a-53e7-4e50-ab3e-44cfd5831579/9781138337992_oachapter3.pdf X:OAPEN Verlag OAPEN Library: download the publication kostenfrei https://library.oapen.org/handle/20.500.12657/40106 X:OAPEN Verlag OAPEN Library: description of the publication kostenfrei ZDB-94-OAL GBV_ILN_22 ISIL_DE-18 SYSFLAG_1 GBV_KXP GBV_ILN_23 ISIL_DE-830 GBV_ILN_30 ISIL_DE-104 GBV_ILN_31 ISIL_DE-27 GBV_ILN_34 ISIL_DE-18-302 GBV_ILN_39 ISIL_DE-547 GBV_ILN_40 ISIL_DE-7 GBV_ILN_63 ISIL_DE-Wim2 GBV_ILN_65 ISIL_DE-3 GBV_ILN_70 ISIL_DE-89 GBV_ILN_72 ISIL_DE-35 GBV_ILN_95 ISIL_DE-542 GBV_ILN_110 ISIL_DE-Luen4 GBV_ILN_136 ISIL_DE-Wis1 GBV_ILN_147 ISIL_DE-Fl3 GBV_ILN_161 ISIL_DE-960 GBV_ILN_187 ISIL_DE-Ki95 GBV_ILN_213 ISIL_DE-551 GBV_ILN_230 ISIL_DE-552 GBV_ILN_283 ISIL_DE-Ha163 GBV_ILN_293 ISIL_DE-960-3 GBV_ILN_370 ISIL_DE-1373 GBV_ILN_603 ISIL_DE-B1556 GBV_ILN_808 GBV_ILN_2403 ISIL_DE-LFER BO 22 01 0018 4280105650 OLR-ZDB-94-OAL OAPEN Library zu 01-03-23 23 01 0830 4280657653 OLR-OAPEN f z 01-03-23 30 01 0104 4281018026 GBV-OAPEN z 01-03-23 31 01 0027 4280300399 z 01-03-23 34 01 3551 4278855923 OLR-OAPEN zi002 01-03-23 39 01 0547 4281208844 GBV-OAPEN ke 01-03-23 40 01 0007 4279924422 OLR-OAPEN xsn 01-03-23 63 01 3401 4281589783 E-Books LF GBV-OAPEN z 01-03-23 65 01 0003 4281840893 OLR-OAPEN z 01-03-23 70 01 0089 4280478627 OLR-OAPEN-OA OAPEN Online Library Open Access eBook z 01-03-23 72 01 0035 4278676689 OLR-OAPEN-OA OAPEN Online Library Open Access eBook z 01-03-23 95 01 3095 4343204413 OLR-OAL Vervielfältigungen (z.B. 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spelling	(DE-627)1836447515 (DE-599)KEP062186205 (OCoLC)1286318426 (OAPEN)40106 (EBP)062186205 DE-627 eng DE-627 rda eng MMG bicssc PSD bicssc PS bicssc MKG bicssc Nydegger, Damien verfasserin aut Chapter 3 Vitamin C Alimentation via SLC Solute Carriers [Erscheinungsort nicht ermittelbar] Taylor & Francis 2020 1 Online-Ressource (18 p.) Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Open Access Unrestricted online access star Although mortality rates from pneumonia and sepsis are decreasing in many parts of the world, the incidence of these conditions continues to rise, likely due to an increasingly ageing population. Case reports and observational studies indicate a strong association between vitamin C status and infectious conditions, with vitamin C deficiency predisposing individuals to infections, and conversely, infections precipitating a diminished vitamin C status. The requirements for vitamin C increase with the severity of the infectious condition, with gram amounts required to normalize the vitamin C status of critically ill patients. Over the past few years, there has been renewed interest in the role that vitamin C may play in severe infectious conditions. Vitamin C has a plethora of physiological effects, primarily due to its activity as a cofactor for a growing group of biosynthetic and regulatory enzymes, with the potential to regulate thousands of genes and cell signaling pathways. Small intervention studies have indicated that administration of gram doses of vitamin C to patients with pneumonia and sepsis improves organ function and potentially decreases mortality, although this remains to be confirmed in larger trials. The long-term quality of life outcomes of these patients also remains to be determined Creative Commons https://creativecommons.org/licenses/by-nc-nd/4.0 cc English Pharmacology Molecular biology Biology, life sciences Gyimesi, Gergely oth Hediger, Matthias oth https://library.oapen.org/bitstream/id/13c0ef0a-53e7-4e50-ab3e-44cfd5831579/9781138337992_oachapter3.pdf X:OAPEN Verlag OAPEN Library: download the publication kostenfrei https://library.oapen.org/handle/20.500.12657/40106 X:OAPEN Verlag OAPEN Library: description of the publication kostenfrei ZDB-94-OAL GBV_ILN_22 ISIL_DE-18 SYSFLAG_1 GBV_KXP GBV_ILN_23 ISIL_DE-830 GBV_ILN_30 ISIL_DE-104 GBV_ILN_31 ISIL_DE-27 GBV_ILN_34 ISIL_DE-18-302 GBV_ILN_39 ISIL_DE-547 GBV_ILN_40 ISIL_DE-7 GBV_ILN_63 ISIL_DE-Wim2 GBV_ILN_65 ISIL_DE-3 GBV_ILN_70 ISIL_DE-89 GBV_ILN_72 ISIL_DE-35 GBV_ILN_95 ISIL_DE-542 GBV_ILN_110 ISIL_DE-Luen4 GBV_ILN_136 ISIL_DE-Wis1 GBV_ILN_147 ISIL_DE-Fl3 GBV_ILN_161 ISIL_DE-960 GBV_ILN_187 ISIL_DE-Ki95 GBV_ILN_213 ISIL_DE-551 GBV_ILN_230 ISIL_DE-552 GBV_ILN_283 ISIL_DE-Ha163 GBV_ILN_293 ISIL_DE-960-3 GBV_ILN_370 ISIL_DE-1373 GBV_ILN_603 ISIL_DE-B1556 GBV_ILN_808 GBV_ILN_2403 ISIL_DE-LFER BO 22 01 0018 4280105650 OLR-ZDB-94-OAL OAPEN Library zu 01-03-23 23 01 0830 4280657653 OLR-OAPEN f z 01-03-23 30 01 0104 4281018026 GBV-OAPEN z 01-03-23 31 01 0027 4280300399 z 01-03-23 34 01 3551 4278855923 OLR-OAPEN zi002 01-03-23 39 01 0547 4281208844 GBV-OAPEN ke 01-03-23 40 01 0007 4279924422 OLR-OAPEN xsn 01-03-23 63 01 3401 4281589783 E-Books LF GBV-OAPEN z 01-03-23 65 01 0003 4281840893 OLR-OAPEN z 01-03-23 70 01 0089 4280478627 OLR-OAPEN-OA OAPEN Online Library Open Access eBook z 01-03-23 72 01 0035 4278676689 OLR-OAPEN-OA OAPEN Online Library Open Access eBook z 01-03-23 95 01 3095 4343204413 OLR-OAL Vervielfältigungen (z.B. Kopien, Downloads) sind nur von einzelnen Kapiteln oder Seiten und nur zum eigenen wissenschaftlichen Gebrauch erlaubt. Die Weitergabe an Dritte sowie systematisches Downloaden sind untersagt. z 24-06-23 110 01 3110 4281393749 OLR-GBV-OAPEN Open Access z 01-03-23 136 01 3526 427956549X OLR-OAPEN z 01-03-23 147 01 3528 4282038616 OLR-OAPEN frei verfügbar für Europa-Universität Flensburg, Hochschule Flensburg und Zentrale Hochschulbibliothek Vervielfältigungen (z.B. Kopien, Downloads) sind nur von einzelnen Kapiteln oder Seiten und nur zum eigenen wissenschaftlichen Gebrauch erlaubt. Die Weitergabe an Dritte sowie systematisches Downloaden sind untersagt. z 01-03-23 161 01 0960 427811222X OLR-OAPEN OAPEN Online Library Open Access eBook z 28-02-23 187 01 3520 4278497091 JSTOR Open Access eBook z 28-02-23 213 01 0551 4279211108 OLR-OAPEN OAPEN Online Library Open Access eBook z 01-03-23 230 01 0552 4279388288 OLR-OAPEN OAPEN Online Library Open Access eBook z 01-03-23 283 01 3283 4279747199 OLR-OAL z 01-03-23 293 01 3293 4278291310 OLR-OAPEN OAPEN Online Library Open Access eBook z 28-02-23 370 01 4370 4279033676 OLR-FREE Kostenloser Zugriff z 01-03-23 603 01 4603 4277934323 OLR-OAPEN Bitte beachten Sie die Nutzungsbedingungen und Copyright-Bestimmungen des Verlages/Herausgebers. z 28-02-23 808 01 4808 4280836566 OLR-OAPEN OAPEN Library zg 01-03-23 2403 01 DE-LFER 4307521803 00 --%%-- --%%-- n --%%-- l01 11-04-23 22 01 0018 Volltextzugang https://library.oapen.org/handle/20.500.12657/40106 23 01 0830 https://library.oapen.org/handle/20.500.12657/40106 30 01 0104 Open Access https://library.oapen.org/handle/20.500.12657/40106 31 01 0027 eBook GBV-OAPEN https://library.oapen.org/handle/20.500.12657/40106 34 01 3551 OpenAccess https://library.oapen.org/handle/20.500.12657/40106 40 01 0007 Volltext, Open Access https://library.oapen.org/handle/20.500.12657/40106 63 01 3401 E-Book https://library.oapen.org/handle/20.500.12657/40106 65 01 0003 Open Access https://library.oapen.org/handle/20.500.12657/40106 65 01 0003 Dieser Titel ist Teil einer Datenbank http://www.bibliothek.uni-regensburg.de/dbinfo/detail.php?titel_id=10728&bib_id=ulb_hal 70 01 0089 https://library.oapen.org/handle/20.500.12657/40106 LF 72 01 0035 https://library.oapen.org/handle/20.500.12657/40106 95 01 3095 https://library.oapen.org/handle/20.500.12657/40106 110 01 3110 Open Access https://library.oapen.org/handle/20.500.12657/40106 136 01 3526 Open Access https://library.oapen.org/handle/20.500.12657/40106 147 01 3528 https://library.oapen.org/handle/20.500.12657/40106 161 01 0960 https://library.oapen.org/handle/20.500.12657/40106 LF 187 01 3520 https://library.oapen.org/handle/20.500.12657/40106 213 01 0551 https://library.oapen.org/handle/20.500.12657/40106 230 01 0552 https://library.oapen.org/handle/20.500.12657/40106 283 01 3283 https://library.oapen.org/handle/20.500.12657/40106 293 01 3293 https://library.oapen.org/handle/20.500.12657/40106 LF 370 01 4370 https://library.oapen.org/handle/20.500.12657/40106 603 01 4603 https://library.oapen.org/handle/20.500.12657/40106 808 01 4808 Volltextzugang https://library.oapen.org/handle/20.500.12657/40106 2403 01 DE-LFER https://library.oapen.org/bitstream/id/13c0ef0a-53e7-4e50-ab3e-44cfd5831579/9781138337992_oachapter3.pdf 31 01 0027 00 eBook GBV-OAPEN 22 01 0018 OLR-ZDB-94-OAL 23 01 0830 OLR-OAPEN 30 01 0104 GBV-OAPEN 34 01 3551 OLR-OAPEN 39 01 0547 GBV-OAPEN 39 01 0547 LF 40 01 0007 OLR-OAPEN 63 01 3401 E-Books LF GBV-OAPEN 65 01 0003 OLR-OAPEN 70 01 0089 OLR-OAPEN-OA 72 01 0035 OLR-OAPEN-OA 95 01 3095 OLR-OAL 110 01 3110 OLR-GBV-OAPEN 136 01 3526 OLR-OAPEN 147 01 3528 OLR-OAPEN 161 01 0960 OLR-OAPEN 213 01 0551 OLR-OAPEN 230 01 0552 OLR-OAPEN 283 01 3283 OLR-OAL 293 01 3293 OLR-OAPEN 370 01 4370 OLR-FREE 370 01 4370 olr-ebook GBV-OAPEN 603 01 4603 OLR-OAPEN 808 01 4808 OLR-OAPEN
allfields_unstemmed	(DE-627)1836447515 (DE-599)KEP062186205 (OCoLC)1286318426 (OAPEN)40106 (EBP)062186205 DE-627 eng DE-627 rda eng MMG bicssc PSD bicssc PS bicssc MKG bicssc Nydegger, Damien verfasserin aut Chapter 3 Vitamin C Alimentation via SLC Solute Carriers [Erscheinungsort nicht ermittelbar] Taylor & Francis 2020 1 Online-Ressource (18 p.) Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Open Access Unrestricted online access star Although mortality rates from pneumonia and sepsis are decreasing in many parts of the world, the incidence of these conditions continues to rise, likely due to an increasingly ageing population. Case reports and observational studies indicate a strong association between vitamin C status and infectious conditions, with vitamin C deficiency predisposing individuals to infections, and conversely, infections precipitating a diminished vitamin C status. The requirements for vitamin C increase with the severity of the infectious condition, with gram amounts required to normalize the vitamin C status of critically ill patients. Over the past few years, there has been renewed interest in the role that vitamin C may play in severe infectious conditions. Vitamin C has a plethora of physiological effects, primarily due to its activity as a cofactor for a growing group of biosynthetic and regulatory enzymes, with the potential to regulate thousands of genes and cell signaling pathways. Small intervention studies have indicated that administration of gram doses of vitamin C to patients with pneumonia and sepsis improves organ function and potentially decreases mortality, although this remains to be confirmed in larger trials. The long-term quality of life outcomes of these patients also remains to be determined Creative Commons https://creativecommons.org/licenses/by-nc-nd/4.0 cc English Pharmacology Molecular biology Biology, life sciences Gyimesi, Gergely oth Hediger, Matthias oth https://library.oapen.org/bitstream/id/13c0ef0a-53e7-4e50-ab3e-44cfd5831579/9781138337992_oachapter3.pdf X:OAPEN Verlag OAPEN Library: download the publication kostenfrei https://library.oapen.org/handle/20.500.12657/40106 X:OAPEN Verlag OAPEN Library: description of the publication kostenfrei ZDB-94-OAL GBV_ILN_22 ISIL_DE-18 SYSFLAG_1 GBV_KXP GBV_ILN_23 ISIL_DE-830 GBV_ILN_30 ISIL_DE-104 GBV_ILN_31 ISIL_DE-27 GBV_ILN_34 ISIL_DE-18-302 GBV_ILN_39 ISIL_DE-547 GBV_ILN_40 ISIL_DE-7 GBV_ILN_63 ISIL_DE-Wim2 GBV_ILN_65 ISIL_DE-3 GBV_ILN_70 ISIL_DE-89 GBV_ILN_72 ISIL_DE-35 GBV_ILN_95 ISIL_DE-542 GBV_ILN_110 ISIL_DE-Luen4 GBV_ILN_136 ISIL_DE-Wis1 GBV_ILN_147 ISIL_DE-Fl3 GBV_ILN_161 ISIL_DE-960 GBV_ILN_187 ISIL_DE-Ki95 GBV_ILN_213 ISIL_DE-551 GBV_ILN_230 ISIL_DE-552 GBV_ILN_283 ISIL_DE-Ha163 GBV_ILN_293 ISIL_DE-960-3 GBV_ILN_370 ISIL_DE-1373 GBV_ILN_603 ISIL_DE-B1556 GBV_ILN_808 GBV_ILN_2403 ISIL_DE-LFER BO 22 01 0018 4280105650 OLR-ZDB-94-OAL OAPEN Library zu 01-03-23 23 01 0830 4280657653 OLR-OAPEN f z 01-03-23 30 01 0104 4281018026 GBV-OAPEN z 01-03-23 31 01 0027 4280300399 z 01-03-23 34 01 3551 4278855923 OLR-OAPEN zi002 01-03-23 39 01 0547 4281208844 GBV-OAPEN ke 01-03-23 40 01 0007 4279924422 OLR-OAPEN xsn 01-03-23 63 01 3401 4281589783 E-Books LF GBV-OAPEN z 01-03-23 65 01 0003 4281840893 OLR-OAPEN z 01-03-23 70 01 0089 4280478627 OLR-OAPEN-OA OAPEN Online Library Open Access eBook z 01-03-23 72 01 0035 4278676689 OLR-OAPEN-OA OAPEN Online Library Open Access eBook z 01-03-23 95 01 3095 4343204413 OLR-OAL Vervielfältigungen (z.B. Kopien, Downloads) sind nur von einzelnen Kapiteln oder Seiten und nur zum eigenen wissenschaftlichen Gebrauch erlaubt. Die Weitergabe an Dritte sowie systematisches Downloaden sind untersagt. z 24-06-23 110 01 3110 4281393749 OLR-GBV-OAPEN Open Access z 01-03-23 136 01 3526 427956549X OLR-OAPEN z 01-03-23 147 01 3528 4282038616 OLR-OAPEN frei verfügbar für Europa-Universität Flensburg, Hochschule Flensburg und Zentrale Hochschulbibliothek Vervielfältigungen (z.B. Kopien, Downloads) sind nur von einzelnen Kapiteln oder Seiten und nur zum eigenen wissenschaftlichen Gebrauch erlaubt. Die Weitergabe an Dritte sowie systematisches Downloaden sind untersagt. z 01-03-23 161 01 0960 427811222X OLR-OAPEN OAPEN Online Library Open Access eBook z 28-02-23 187 01 3520 4278497091 JSTOR Open Access eBook z 28-02-23 213 01 0551 4279211108 OLR-OAPEN OAPEN Online Library Open Access eBook z 01-03-23 230 01 0552 4279388288 OLR-OAPEN OAPEN Online Library Open Access eBook z 01-03-23 283 01 3283 4279747199 OLR-OAL z 01-03-23 293 01 3293 4278291310 OLR-OAPEN OAPEN Online Library Open Access eBook z 28-02-23 370 01 4370 4279033676 OLR-FREE Kostenloser Zugriff z 01-03-23 603 01 4603 4277934323 OLR-OAPEN Bitte beachten Sie die Nutzungsbedingungen und Copyright-Bestimmungen des Verlages/Herausgebers. z 28-02-23 808 01 4808 4280836566 OLR-OAPEN OAPEN Library zg 01-03-23 2403 01 DE-LFER 4307521803 00 --%%-- --%%-- n --%%-- l01 11-04-23 22 01 0018 Volltextzugang https://library.oapen.org/handle/20.500.12657/40106 23 01 0830 https://library.oapen.org/handle/20.500.12657/40106 30 01 0104 Open Access https://library.oapen.org/handle/20.500.12657/40106 31 01 0027 eBook GBV-OAPEN https://library.oapen.org/handle/20.500.12657/40106 34 01 3551 OpenAccess https://library.oapen.org/handle/20.500.12657/40106 40 01 0007 Volltext, Open Access https://library.oapen.org/handle/20.500.12657/40106 63 01 3401 E-Book https://library.oapen.org/handle/20.500.12657/40106 65 01 0003 Open Access https://library.oapen.org/handle/20.500.12657/40106 65 01 0003 Dieser Titel ist Teil einer Datenbank http://www.bibliothek.uni-regensburg.de/dbinfo/detail.php?titel_id=10728&bib_id=ulb_hal 70 01 0089 https://library.oapen.org/handle/20.500.12657/40106 LF 72 01 0035 https://library.oapen.org/handle/20.500.12657/40106 95 01 3095 https://library.oapen.org/handle/20.500.12657/40106 110 01 3110 Open Access https://library.oapen.org/handle/20.500.12657/40106 136 01 3526 Open Access https://library.oapen.org/handle/20.500.12657/40106 147 01 3528 https://library.oapen.org/handle/20.500.12657/40106 161 01 0960 https://library.oapen.org/handle/20.500.12657/40106 LF 187 01 3520 https://library.oapen.org/handle/20.500.12657/40106 213 01 0551 https://library.oapen.org/handle/20.500.12657/40106 230 01 0552 https://library.oapen.org/handle/20.500.12657/40106 283 01 3283 https://library.oapen.org/handle/20.500.12657/40106 293 01 3293 https://library.oapen.org/handle/20.500.12657/40106 LF 370 01 4370 https://library.oapen.org/handle/20.500.12657/40106 603 01 4603 https://library.oapen.org/handle/20.500.12657/40106 808 01 4808 Volltextzugang https://library.oapen.org/handle/20.500.12657/40106 2403 01 DE-LFER https://library.oapen.org/bitstream/id/13c0ef0a-53e7-4e50-ab3e-44cfd5831579/9781138337992_oachapter3.pdf 31 01 0027 00 eBook GBV-OAPEN 22 01 0018 OLR-ZDB-94-OAL 23 01 0830 OLR-OAPEN 30 01 0104 GBV-OAPEN 34 01 3551 OLR-OAPEN 39 01 0547 GBV-OAPEN 39 01 0547 LF 40 01 0007 OLR-OAPEN 63 01 3401 E-Books LF GBV-OAPEN 65 01 0003 OLR-OAPEN 70 01 0089 OLR-OAPEN-OA 72 01 0035 OLR-OAPEN-OA 95 01 3095 OLR-OAL 110 01 3110 OLR-GBV-OAPEN 136 01 3526 OLR-OAPEN 147 01 3528 OLR-OAPEN 161 01 0960 OLR-OAPEN 213 01 0551 OLR-OAPEN 230 01 0552 OLR-OAPEN 283 01 3283 OLR-OAL 293 01 3293 OLR-OAPEN 370 01 4370 OLR-FREE 370 01 4370 olr-ebook GBV-OAPEN 603 01 4603 OLR-OAPEN 808 01 4808 OLR-OAPEN
allfieldsGer	(DE-627)1836447515 (DE-599)KEP062186205 (OCoLC)1286318426 (OAPEN)40106 (EBP)062186205 DE-627 eng DE-627 rda eng MMG bicssc PSD bicssc PS bicssc MKG bicssc Nydegger, Damien verfasserin aut Chapter 3 Vitamin C Alimentation via SLC Solute Carriers [Erscheinungsort nicht ermittelbar] Taylor & Francis 2020 1 Online-Ressource (18 p.) Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Open Access Unrestricted online access star Although mortality rates from pneumonia and sepsis are decreasing in many parts of the world, the incidence of these conditions continues to rise, likely due to an increasingly ageing population. Case reports and observational studies indicate a strong association between vitamin C status and infectious conditions, with vitamin C deficiency predisposing individuals to infections, and conversely, infections precipitating a diminished vitamin C status. The requirements for vitamin C increase with the severity of the infectious condition, with gram amounts required to normalize the vitamin C status of critically ill patients. Over the past few years, there has been renewed interest in the role that vitamin C may play in severe infectious conditions. Vitamin C has a plethora of physiological effects, primarily due to its activity as a cofactor for a growing group of biosynthetic and regulatory enzymes, with the potential to regulate thousands of genes and cell signaling pathways. Small intervention studies have indicated that administration of gram doses of vitamin C to patients with pneumonia and sepsis improves organ function and potentially decreases mortality, although this remains to be confirmed in larger trials. The long-term quality of life outcomes of these patients also remains to be determined Creative Commons https://creativecommons.org/licenses/by-nc-nd/4.0 cc English Pharmacology Molecular biology Biology, life sciences Gyimesi, Gergely oth Hediger, Matthias oth https://library.oapen.org/bitstream/id/13c0ef0a-53e7-4e50-ab3e-44cfd5831579/9781138337992_oachapter3.pdf X:OAPEN Verlag OAPEN Library: download the publication kostenfrei https://library.oapen.org/handle/20.500.12657/40106 X:OAPEN Verlag OAPEN Library: description of the publication kostenfrei ZDB-94-OAL GBV_ILN_22 ISIL_DE-18 SYSFLAG_1 GBV_KXP GBV_ILN_23 ISIL_DE-830 GBV_ILN_30 ISIL_DE-104 GBV_ILN_31 ISIL_DE-27 GBV_ILN_34 ISIL_DE-18-302 GBV_ILN_39 ISIL_DE-547 GBV_ILN_40 ISIL_DE-7 GBV_ILN_63 ISIL_DE-Wim2 GBV_ILN_65 ISIL_DE-3 GBV_ILN_70 ISIL_DE-89 GBV_ILN_72 ISIL_DE-35 GBV_ILN_95 ISIL_DE-542 GBV_ILN_110 ISIL_DE-Luen4 GBV_ILN_136 ISIL_DE-Wis1 GBV_ILN_147 ISIL_DE-Fl3 GBV_ILN_161 ISIL_DE-960 GBV_ILN_187 ISIL_DE-Ki95 GBV_ILN_213 ISIL_DE-551 GBV_ILN_230 ISIL_DE-552 GBV_ILN_283 ISIL_DE-Ha163 GBV_ILN_293 ISIL_DE-960-3 GBV_ILN_370 ISIL_DE-1373 GBV_ILN_603 ISIL_DE-B1556 GBV_ILN_808 GBV_ILN_2403 ISIL_DE-LFER BO 22 01 0018 4280105650 OLR-ZDB-94-OAL OAPEN Library zu 01-03-23 23 01 0830 4280657653 OLR-OAPEN f z 01-03-23 30 01 0104 4281018026 GBV-OAPEN z 01-03-23 31 01 0027 4280300399 z 01-03-23 34 01 3551 4278855923 OLR-OAPEN zi002 01-03-23 39 01 0547 4281208844 GBV-OAPEN ke 01-03-23 40 01 0007 4279924422 OLR-OAPEN xsn 01-03-23 63 01 3401 4281589783 E-Books LF GBV-OAPEN z 01-03-23 65 01 0003 4281840893 OLR-OAPEN z 01-03-23 70 01 0089 4280478627 OLR-OAPEN-OA OAPEN Online Library Open Access eBook z 01-03-23 72 01 0035 4278676689 OLR-OAPEN-OA OAPEN Online Library Open Access eBook z 01-03-23 95 01 3095 4343204413 OLR-OAL Vervielfältigungen (z.B. 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topic_title	31 01 0027 00 eBook GBV-OAPEN Chapter 3 Vitamin C Alimentation via SLC Solute Carriers Pharmacology Molecular biology Biology, life sciences
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title_sort	chapter 3 vitamin c alimentation via slc solute carriers
title_auth	Chapter 3 Vitamin C Alimentation via SLC Solute Carriers
abstract	Although mortality rates from pneumonia and sepsis are decreasing in many parts of the world, the incidence of these conditions continues to rise, likely due to an increasingly ageing population. Case reports and observational studies indicate a strong association between vitamin C status and infectious conditions, with vitamin C deficiency predisposing individuals to infections, and conversely, infections precipitating a diminished vitamin C status. The requirements for vitamin C increase with the severity of the infectious condition, with gram amounts required to normalize the vitamin C status of critically ill patients. Over the past few years, there has been renewed interest in the role that vitamin C may play in severe infectious conditions. Vitamin C has a plethora of physiological effects, primarily due to its activity as a cofactor for a growing group of biosynthetic and regulatory enzymes, with the potential to regulate thousands of genes and cell signaling pathways. Small intervention studies have indicated that administration of gram doses of vitamin C to patients with pneumonia and sepsis improves organ function and potentially decreases mortality, although this remains to be confirmed in larger trials. The long-term quality of life outcomes of these patients also remains to be determined
abstractGer	Although mortality rates from pneumonia and sepsis are decreasing in many parts of the world, the incidence of these conditions continues to rise, likely due to an increasingly ageing population. Case reports and observational studies indicate a strong association between vitamin C status and infectious conditions, with vitamin C deficiency predisposing individuals to infections, and conversely, infections precipitating a diminished vitamin C status. The requirements for vitamin C increase with the severity of the infectious condition, with gram amounts required to normalize the vitamin C status of critically ill patients. Over the past few years, there has been renewed interest in the role that vitamin C may play in severe infectious conditions. Vitamin C has a plethora of physiological effects, primarily due to its activity as a cofactor for a growing group of biosynthetic and regulatory enzymes, with the potential to regulate thousands of genes and cell signaling pathways. Small intervention studies have indicated that administration of gram doses of vitamin C to patients with pneumonia and sepsis improves organ function and potentially decreases mortality, although this remains to be confirmed in larger trials. The long-term quality of life outcomes of these patients also remains to be determined
abstract_unstemmed	Although mortality rates from pneumonia and sepsis are decreasing in many parts of the world, the incidence of these conditions continues to rise, likely due to an increasingly ageing population. Case reports and observational studies indicate a strong association between vitamin C status and infectious conditions, with vitamin C deficiency predisposing individuals to infections, and conversely, infections precipitating a diminished vitamin C status. The requirements for vitamin C increase with the severity of the infectious condition, with gram amounts required to normalize the vitamin C status of critically ill patients. Over the past few years, there has been renewed interest in the role that vitamin C may play in severe infectious conditions. Vitamin C has a plethora of physiological effects, primarily due to its activity as a cofactor for a growing group of biosynthetic and regulatory enzymes, with the potential to regulate thousands of genes and cell signaling pathways. Small intervention studies have indicated that administration of gram doses of vitamin C to patients with pneumonia and sepsis improves organ function and potentially decreases mortality, although this remains to be confirmed in larger trials. The long-term quality of life outcomes of these patients also remains to be determined
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title_short	Chapter 3 Vitamin C Alimentation via SLC Solute Carriers
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Chapter 3 Vitamin C Alimentation via SLC Solute Carriers

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