The investigation of acute toxicity of water-soluble polysaccharides extracted from calamus root (Acorus calamus L.)

An investigation for a possible acute toxicity of the complex of water-soluble polysaccharides (WSPS) extracted from calamus root (Acorus calamus L.) has been performed. No toxic effect has been observed on the organisms of experimental animals after a twofold intragastric, subcutaneous, and intrave...
Ausführliche Beschreibung

An investigation for a possible acute toxicity of the complex of water-soluble polysaccharides (WSPS) extracted from calamus root (Acorus calamus L.) has been performed. No toxic effect has been observed on the organisms of experimental animals after a twofold intragastric, subcutaneous, and intravenous introduction of the highest maximum dose of the WSPS being investigated. The results of the experiments did not allow detecting the average fatal dose (LD50) of the WSPS being investigated as no deaths among the experimental animals had been observed. The obtained data lead to the conclusion that the WSPS of calamus root are to be added to Substance Hazard Class IV (low hazard substances) in compliance with State Standard GOST 12.1.007-76. Ausführliche Beschreibung