Hilfe beim Zugang
Haben Sie den VPN-Client gestartet bzw. sind Sie via Shibboleth angemeldet (weitere Informationen)?
LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival
Inflammatory bowel disease is characterised by epithelial dysfunction. Here the authors show that loss of the nuclear receptor LRH-1 leads to epithelial disruption by altering Notch signaling in mouse intestinal organoids, and that LRH-1 overexpression ameliorates immune-mediated colitis in a mouse...
Ausführliche Beschreibung