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Inter-eye genomic heterogeneity in bilateral retinoblastoma via aqueous humor liquid biopsy

Abstract Germline alterations in the RB1 tumor suppressor gene predispose patients to develop retinoblastoma (RB) in both eyes. While similar treatment is given for each eye, there is often a variable therapeutic response between the eyes. Herein, we use the aqueous humor (AH) liquid biopsy to evalu...
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