Impact of Bacillus Calmette–Guérin Moreau vaccine on lung remodeling in experimental asthma

• In the present model of allergic asthma, BCG-Moreau prevented airway inflammation. • BCG also minimized lung remodeling and airway hyperresponsiveness. • These beneficial effects of BCG may be related to the increase in Foxp3 and IL-10. • BCG acted in asthma independent of administration route and...
Ausführliche Beschreibung

• In the present model of allergic asthma, BCG-Moreau prevented airway inflammation. • BCG also minimized lung remodeling and airway hyperresponsiveness. • These beneficial effects of BCG may be related to the increase in Foxp3 and IL-10. • BCG acted in asthma independent of administration route and vaccination time. Ausführliche Beschreibung