Group comparison of cortical fiber connectivity map: An application between post-stroke patients and healthy subjects

• This study showed the feasibility of applying group comparison vertex-wise analysis for cortical structural connectivity. • A fiber connectivity density (FiCD) method based on connectome method was applied to measure whole-brain FiCD map. • Stroke and healthy participants were enrolled for the FiC...
Ausführliche Beschreibung

• This study showed the feasibility of applying group comparison vertex-wise analysis for cortical structural connectivity. • A fiber connectivity density (FiCD) method based on connectome method was applied to measure whole-brain FiCD map. • Stroke and healthy participants were enrolled for the FiCD measurement and their FiCD maps were statistically compared. • There was a spatial consistency between the cortical clusters with low FiCD values and the subcortical lesions of patients. • The FiCD method possessed good reproducibility, and could accurately reflect the affected cortical regions in patients. Ausführliche Beschreibung