Subtle changes in Plasmodium falciparum infection complexity following enhanced intervention in Malawi

Highlights • We examined impact of intense malaria control on parasite genetic structure in Malawi. • Malaria infections sampled before and after intense control were genotyped at 24 SNPs. • Despite intense control efforts, parasite genetic diversity was unchanged over time. • Only the mean number o...
Ausführliche Beschreibung

Highlights • We examined impact of intense malaria control on parasite genetic structure in Malawi. • Malaria infections sampled before and after intense control were genotyped at 24 SNPs. • Despite intense control efforts, parasite genetic diversity was unchanged over time. • Only the mean number of heterozygous SNPs within infections showed change over time. • Findings suggest minimal or no change in malaria transmission despite intense control. Ausführliche Beschreibung