Timing temporal transitions during brain development

• Temporal patterning of neural progenitors is a conserved strategy to generate cell diversity. • In Drosophila, tTFs deterministically regulate cell fate. • In vertebrates, tTFs bias stochastic cell-fate decisions towards specific fates. • Intrinsic and extrinsic cues can regulate temporal transiti...
Ausführliche Beschreibung

• Temporal patterning of neural progenitors is a conserved strategy to generate cell diversity. • In Drosophila, tTFs deterministically regulate cell fate. • In vertebrates, tTFs bias stochastic cell-fate decisions towards specific fates. • Intrinsic and extrinsic cues can regulate temporal transitions. Ausführliche Beschreibung