Immune checkpoint blockade for unresectable or metastatic uveal melanoma: A systematic review

• Metastatic uveal melanoma (UM) is an orphan disease of high unmet need. • The current use of immune checkpoint blockade in UM is not evidence-based. • A systematic review on immune checkpoint blockade for UM was performed. • CTLA-4 blockade lacks efficacy but maintains toxicity in metastatic UM....
Ausführliche Beschreibung

• Metastatic uveal melanoma (UM) is an orphan disease of high unmet need. • The current use of immune checkpoint blockade in UM is not evidence-based. • A systematic review on immune checkpoint blockade for UM was performed. • CTLA-4 blockade lacks efficacy but maintains toxicity in metastatic UM. Ausführliche Beschreibung