Diethanolamine-modified pectin based core-shell composites as dual working gastroretentive drug-cargo

• DMP with degree of amidation of 48.72% was synthesized. • MFM-loaded core-shell DMP-ALG composites were accomplished. • Formulation variables influenced DEE and Q8h values. • Formulation F-7 exhibited high DEE with extended drug release at 8h. • It depicted excellent gastroretentive characteristic...
Ausführliche Beschreibung

• DMP with degree of amidation of 48.72% was synthesized. • MFM-loaded core-shell DMP-ALG composites were accomplished. • Formulation variables influenced DEE and Q8h values. • Formulation F-7 exhibited high DEE with extended drug release at 8h. • It depicted excellent gastroretentive characteristics. Ausführliche Beschreibung