Sex hormones and immune system: A possible interplay in affective disorders? A systematic review

• The gonadal-immune interplay in depression is unclear. • Testosterone may be protective in bipolar depression in men through anti-inflammatory effects. • Hormonal therapy may be protective in peri/post menopausal women through anti-inflammatory effects. • Conclusions limited by study number and st...
Ausführliche Beschreibung

• The gonadal-immune interplay in depression is unclear. • Testosterone may be protective in bipolar depression in men through anti-inflammatory effects. • Hormonal therapy may be protective in peri/post menopausal women through anti-inflammatory effects. • Conclusions limited by study number and study heterogeneity Ausführliche Beschreibung