Fed or fasted state for oral therapies in breast cancer treatment? A comprehensive review of clinical practice recommendations

• Oral therapies have improved quality of life of breast cancer patients. • High variability in exposure can occur with orally administered drugs. • Fed or fasted state are major determinants of oral drug pharmacokinetics. • Awareness of possible food-drug interactions is required to optimize treatm...
Ausführliche Beschreibung

• Oral therapies have improved quality of life of breast cancer patients. • High variability in exposure can occur with orally administered drugs. • Fed or fasted state are major determinants of oral drug pharmacokinetics. • Awareness of possible food-drug interactions is required to optimize treatment. Ausführliche Beschreibung