Prolonged suppression of pituitary and pancreatic hormone release by a somatostatin analog

A potent analog of somatostatin has been synthesized which suppresses plasma levels of growth hormone, insulin and glucagon in short term experiments in rats (15 minutes from analog administration to blood sampling). This analog lowers plasma growth hormone in rats and plasma glucose and glucagon in...
Ausführliche Beschreibung

A potent analog of somatostatin has been synthesized which suppresses plasma levels of growth hormone, insulin and glucagon in short term experiments in rats (15 minutes from analog administration to blood sampling). This analog lowers plasma growth hormone in rats and plasma glucose and glucagon in streptozotocin diabetic dogs for prolonged periods of time. Ausführliche Beschreibung