Functional parameters of the left ventricle: comparison of cardiac MRI and cardiac CT in a large population

Purpose The authors sought to compare magnetic resonance imaging (MRI) and computed tomography (CT) for assessing left ventricular (LV) function parameters in a large patient population. Materials and methods The study was conducted on 181 patients who underwent cardiac MRI and cardiac CT for variou...
Ausführliche Beschreibung

Purpose The authors sought to compare magnetic resonance imaging (MRI) and computed tomography (CT) for assessing left ventricular (LV) function parameters in a large patient population. Materials and methods The study was conducted on 181 patients who underwent cardiac MRI and cardiac CT for various indications. For MRI, we used two-dimensional cine balanced steady-state free precession (b-SSFP) sequences, and for CT we used multiphase short-axis reconstructions. Volume data sets were evaluated with dedicated software. Results were compared with a paired, two-tailed Student’s t test, Pearson’s correlation (r), and Bland-Altman analysis. Results A high level of concordance was observed between cardiac MRI and CT. Ejection fraction (EF) was 53±14% for MRI vs. 53%±15% for CT. There was good correlation for EF (r=0.71; p>0.05) and end-systolic volume (r=0.74; p>0.05). End-diastolic volume (74±23 ml at MRI vs. 71±19 ml at CT; r=0.58; p<0.05) and myocardial mass (63±20 g at MRI and 56±18 g at CT; r=0.89; p<0.01) showed statistically significant differences, although the discrepancy had no clinical impact. Conclusions MRI and CT show a good level of agreement in assessing LV function parameters, and both can be used interchangeably in clinical practice. Ausführliche Beschreibung