Photochemistry of an alpha lipoic acid-based drug and its application in dual sensing of Fe(III) and Pb(II) and logic gates

The photochemistry of an expired Alpha Lipoic Acid-based drug namely MEGO-XL (ML) was investigated. ML showed its application in selective sensing of $ Fe^{3+} $ and $ Pb^{2+} $ avoiding any interference. The lower detection limit values for $ Fe^{3+} $ (1.51 × $ 10^{−4} $ M) and $ Pb^{2+} $ (72.8 µ...
Ausführliche Beschreibung

The photochemistry of an expired Alpha Lipoic Acid-based drug namely MEGO-XL (ML) was investigated. ML showed its application in selective sensing of $ Fe^{3+} $ and $ Pb^{2+} $ avoiding any interference. The lower detection limit values for $ Fe^{3+} $ (1.51 × $ 10^{−4} $ M) and $ Pb^{2+} $ (72.8 µM) suggested the sensitive nature of ML. The stability of the compound was examined under different environmental conditions. Further, the interaction between ML and $ Fe^{3+} $, $ Pb^{2+} $ was studied with the help of Stern–Volmer plots, Benesi–Hildebrand relation. Increased $ K_{SV} $ values with increased temperature suggested that the nature of quenching was purely dynamic in the case of $ Fe^{3+} $ and decreased $ K_{SV} $ values with increased temperature indicated that there might be an occurrence of static quenching in the case of $ Pb^{2+} $. Ethylenediaminetetra acetic acid (EDTA) was used to differentiate the detection of $ Fe^{3+} $ from $ Pb^{2+} $.ML also showed application in sensing $ TiO_{2} $ nanoparticles and in OR logic gate operations. These experimental outcomes hinted that the chosen expired drug ML can be reused for chemosensing and logic gate applications. Graphical abstract The dual-sensing nature [Fe(III) and Pb(II)] of ML is described through Intensity Vs Wavelength graphs. TiO2 sensing nature of ML is also described by KSV graph. The logic gate application of ML is pictorially represented with a truth table and bar graph. Ausführliche Beschreibung