Suchergebnisse - "O’Farrell, Marie"

1

The FASN inhibitor TVB-2640 is efficacious in a new 3D human liver microtissue model of NASH

von: O’Farrell, Marie

2020, in: Identification of the antigenic region of

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2

Tu1320: NOVEL, FIRST-IN-CLASS, FATTY ACID SYNTHASE (FASN) INHIBITOR TVB-2640: EFFICACY, SAFETY AND BIOMARKER RESULTS FROM A GLOBAL PHASE 2 RANDOMIZED PBO-CONTROLLED NASH TRIAL, FASCINATE-1.

von: Harrison, Stephen

2022, in: Ubiquitin protease Ubp8 is necessary for

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3

Fatty acid synthase – Modern tumor cell biology insights into a classical oncology target

von: Buckley, Douglas

2017transfer abstract, in: Monitoring antioxidants by coulometry: Quantitative assessment of the strikingly high antioxidant capacity of bergamot (

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4

A baseline signature of metabolites involving the gut-liver axis predicts MRI-PDFF response to FASN inhibitor TVB-2640: results from the FASCINATE-1 study

von: Loomba, Rohit

2022, in: Identification of the antigenic region of

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5

Therapeutic efficacy of FASN inhibition in preclinical models of HCC

von: Wang, Haichuan

25 January 2022, in: Hepatology

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6

Novel first-in-class, fatty acid synthase inhibitor, TVB-2640 vs. placebo demonstrates clinically significant reduction in liver fat by MRI-PDFF in NASH: a phase 2 randomised controlled trial (FASCINATE-1)

von: Loomba, Rohit

2020, in: Identification of the antigenic region of

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7

TVB-2640 (FASN Inhibitor) for the Treatment of Nonalcoholic Steatohepatitis: FASCINATE-1, a Randomized, Placebo-Controlled Phase 2a Trial

von: Loomba, Rohit

2021, in: Ubiquitin protease Ubp8 is necessary for

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8

Pharmacological induction of membrane lipid poly-unsaturation sensitizes melanoma to ROS inducers and overcomes acquired resistance to targeted therapy

von: Talebi, Ali

2023, in: Journal of experimental & clinical cancer research

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9

Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use

von: Worthmann, Anna

02 January 2024, in: Nature Communications

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