Free‐breathing combined three‐dimensional phase sensitive late gadolinium enhancement and T1 mapping for myocardial tissue characterization

Purpose To develop a novel MR sequence for combined three?dimensional (3D) phase?sensitive (PS) late gadolinium enhancement (LGE) and T1 mapping to allow for simultaneous assessment of focal and diffuse myocardial fibrosis. Methods In the proposed sequence, four 3D imaging volumes are acquired with...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Weingärtner, Sebastian - 1991- [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2015

Schlagwörter:	3D imaging compressed sensing diffused fibrosis LGE imaging myocardial T1 mapping phase sensitive imaging quantitative cardiac MRI

Anmerkung:	Published online: 16 October 2014 Gesehen am 27.03.2018
Umfang:	10

Übergeordnetes Werk:	Enthalten in: Magnetic resonance in medicine - New York, NY [u.a.] : Wiley-Liss, 1984, 74(2015), 4, Seite 1032-1041
Übergeordnetes Werk:	volume:74 ; year:2015 ; number:4 ; pages:1032-1041 ; extent:10

Links:	Volltext Volltext

DOI / URN:	10.1002/mrm.25495

Katalog-ID:	1571485058

Internformat


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245	1	0	\|a Free‐breathing combined three‐dimensional phase sensitive late gadolinium enhancement and T1 mapping for myocardial tissue characterization \|c Weingärtner Sebastian, Akçakaya Mehmet, Roujol Sébastien, Basha Tamer, Tschabrunn Cory, Berg Sophie, Anter Elad, and Nezafat Reza
264		1	\|c 2015
300			\|a 10
336			\|a Text \|b txt \|2 rdacontent
337			\|a Computermedien \|b c \|2 rdamedia
338			\|a Online-Ressource \|b cr \|2 rdacarrier
500			\|a Published online: 16 October 2014
500			\|a Gesehen am 27.03.2018
520			\|a Purpose To develop a novel MR sequence for combined three?dimensional (3D) phase?sensitive (PS) late gadolinium enhancement (LGE) and T1 mapping to allow for simultaneous assessment of focal and diffuse myocardial fibrosis. Methods In the proposed sequence, four 3D imaging volumes are acquired with different T1 weightings using a combined saturation and inversion preparation, after administration of a gadolinium contrast agent. One image is acquired fully sampled with the inversion time selected to null the healthy myocardial signal (the LGE image). The other three images are three?fold under?sampled and reconstructed using compressed sensing. An acquisition scheme with two interleaved imaging cycles and joint navigator?gating of those cycles ensures spatial registration of the imaging volumes. T1 maps are generated using all four imaging volumes. The signal?polarity in the LGE image is restored using supplementary information from the T1 fit to generate PS?LGE images. The accuracy of the proposed method was assessed with respect to a inversion?recovery spin?echo sequence. In vivo T1 maps and LGE images were acquired with the proposed sequence and quantitatively compared with 2D multislice Modified Look?Locker inversion recovery (MOLLI) T1 maps. Exemplary images in a patient with focal scar were compared with conventional LGE imaging. Results The deviation of the proposed method and the spin?echo reference was?
534			\|c 2014
650		4	\|a 3D imaging
650		4	\|a compressed sensing
650		4	\|a diffused fibrosis
650		4	\|a LGE imaging
650		4	\|a myocardial T1 mapping
650		4	\|a phase sensitive imaging
650		4	\|a quantitative cardiac MRI
773	0	8	\|i Enthalten in \|t Magnetic resonance in medicine \|d New York, NY [u.a.] : Wiley-Liss, 1984 \|g 74(2015), 4, Seite 1032-1041 \|h Online-Ressource \|w (DE-627)303257040 \|w (DE-600)1493786-4 \|w (DE-576)096290455 \|x 1522-2594 \|7 nnns
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912			\|a GBV_USEFLAG_U
912			\|a GBV_ILN_2013
912			\|a ISIL_DE-16-250
912			\|a SYSFLAG_1
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912			\|a SSG-OLC-PHA
912			\|a GBV_ILN_11
912			\|a GBV_ILN_20
912			\|a GBV_ILN_22
912			\|a GBV_ILN_23
912			\|a GBV_ILN_24
912			\|a GBV_ILN_31
912			\|a GBV_ILN_32
912			\|a GBV_ILN_39
912			\|a GBV_ILN_40
912			\|a GBV_ILN_60
912			\|a GBV_ILN_62
912			\|a GBV_ILN_63
912			\|a GBV_ILN_65
912			\|a GBV_ILN_69
912			\|a GBV_ILN_70
912			\|a GBV_ILN_73
912			\|a GBV_ILN_74
912			\|a GBV_ILN_90
912			\|a GBV_ILN_95
912			\|a GBV_ILN_100
912			\|a GBV_ILN_101
912			\|a GBV_ILN_105
912			\|a GBV_ILN_110
912			\|a GBV_ILN_120
912			\|a GBV_ILN_138
912			\|a GBV_ILN_150
912			\|a GBV_ILN_151
912			\|a GBV_ILN_161
912			\|a GBV_ILN_170
912			\|a GBV_ILN_171
912			\|a GBV_ILN_187
912			\|a GBV_ILN_213
912			\|a GBV_ILN_224
912			\|a GBV_ILN_230
912			\|a GBV_ILN_266
912			\|a GBV_ILN_285
912			\|a GBV_ILN_293
912			\|a GBV_ILN_370
912			\|a GBV_ILN_602
912			\|a GBV_ILN_636
912			\|a GBV_ILN_647
912			\|a GBV_ILN_702
912			\|a GBV_ILN_2001
912			\|a GBV_ILN_2003
912			\|a GBV_ILN_2004
912			\|a GBV_ILN_2005
912			\|a GBV_ILN_2006
912			\|a GBV_ILN_2007
912			\|a GBV_ILN_2008
912			\|a GBV_ILN_2009
912			\|a GBV_ILN_2010
912			\|a GBV_ILN_2011
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_2015
912			\|a GBV_ILN_2018
912			\|a GBV_ILN_2020
912			\|a GBV_ILN_2021
912			\|a GBV_ILN_2025
912			\|a GBV_ILN_2026
912			\|a GBV_ILN_2027
912			\|a GBV_ILN_2031
912			\|a GBV_ILN_2034
912			\|a GBV_ILN_2037
912			\|a GBV_ILN_2038
912			\|a GBV_ILN_2039
912			\|a GBV_ILN_2044
912			\|a GBV_ILN_2048
912			\|a GBV_ILN_2049
912			\|a GBV_ILN_2050
912			\|a GBV_ILN_2055
912			\|a GBV_ILN_2056
912			\|a GBV_ILN_2057
912			\|a GBV_ILN_2059
912			\|a GBV_ILN_2061
912			\|a GBV_ILN_2064
912			\|a GBV_ILN_2068
912			\|a GBV_ILN_2088
912			\|a GBV_ILN_2093
912			\|a GBV_ILN_2106
912			\|a GBV_ILN_2108
912			\|a GBV_ILN_2110
912			\|a GBV_ILN_2111
912			\|a GBV_ILN_2112
912			\|a GBV_ILN_2113
912			\|a GBV_ILN_2118
912			\|a GBV_ILN_2119
912			\|a GBV_ILN_2122
912			\|a GBV_ILN_2129
912			\|a GBV_ILN_2143
912			\|a GBV_ILN_2144
912			\|a GBV_ILN_2147
912			\|a GBV_ILN_2148
912			\|a GBV_ILN_2152
912			\|a GBV_ILN_2153
912			\|a GBV_ILN_2188
912			\|a GBV_ILN_2190
912			\|a GBV_ILN_2232
912			\|a GBV_ILN_2336
912			\|a GBV_ILN_2470
912			\|a GBV_ILN_2472
912			\|a GBV_ILN_2507
912			\|a GBV_ILN_2522
912			\|a GBV_ILN_2548
912			\|a GBV_ILN_4012
912			\|a GBV_ILN_4035
912			\|a GBV_ILN_4037
912			\|a GBV_ILN_4046
912			\|a GBV_ILN_4112
912			\|a GBV_ILN_4125
912			\|a GBV_ILN_4126
912			\|a GBV_ILN_4242
912			\|a GBV_ILN_4246
912			\|a GBV_ILN_4249
912			\|a GBV_ILN_4251
912			\|a GBV_ILN_4305
912			\|a GBV_ILN_4306
912			\|a GBV_ILN_4307
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4322
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4326
912			\|a GBV_ILN_4333
912			\|a GBV_ILN_4334
912			\|a GBV_ILN_4335
912			\|a GBV_ILN_4336
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4393
912			\|a GBV_ILN_4700
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952			\|d 74 \|j 2015 \|e 4 \|h 1032-1041 \|g 10
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982			\|2 2013 \|1 01 \|x DE-16-250 \|8 03 \|s s \|a s_10
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 04 \|s p \|0 (DE-627)1477523898 \|a Weingärtner, Sebastian
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 04 \|s k \|0 (DE-627)1430735864 \|a Lehrstuhl für Computerunterstützte Klinische Medizin (CKM)
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 04 \|s s \|0 (DE-627)1410501914 \|a Verfasser
982			\|2 2013 \|1 01 \|x DE-16-250 \|8 04 \|s s \|a pos_1

Indexfelder

author_variant	s w sw
matchkey_str	article:15222594:20152014::rerahncmietreiesoapaeestvltgdlnuehneetntmpigo
oclc_num	1340998410
hierarchy_sort_str	2015
publishDate	2015
allfields	10.1002/mrm.25495 doi (DE-627)1571485058 (DE-576)501485058 (DE-599)BSZ501485058 (OCoLC)1340998410 DE-627 ger DE-627 rda eng Weingärtner, Sebastian 1991- verfasserin (DE-588)1051891507 (DE-627)786975199 (DE-576)407522883 aut Free‐breathing combined three‐dimensional phase sensitive late gadolinium enhancement and T1 mapping for myocardial tissue characterization Weingärtner Sebastian, Akçakaya Mehmet, Roujol Sébastien, Basha Tamer, Tschabrunn Cory, Berg Sophie, Anter Elad, and Nezafat Reza 2015 10 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Published online: 16 October 2014 Gesehen am 27.03.2018 Purpose To develop a novel MR sequence for combined three?dimensional (3D) phase?sensitive (PS) late gadolinium enhancement (LGE) and T1 mapping to allow for simultaneous assessment of focal and diffuse myocardial fibrosis. Methods In the proposed sequence, four 3D imaging volumes are acquired with different T1 weightings using a combined saturation and inversion preparation, after administration of a gadolinium contrast agent. One image is acquired fully sampled with the inversion time selected to null the healthy myocardial signal (the LGE image). The other three images are three?fold under?sampled and reconstructed using compressed sensing. An acquisition scheme with two interleaved imaging cycles and joint navigator?gating of those cycles ensures spatial registration of the imaging volumes. T1 maps are generated using all four imaging volumes. The signal?polarity in the LGE image is restored using supplementary information from the T1 fit to generate PS?LGE images. The accuracy of the proposed method was assessed with respect to a inversion?recovery spin?echo sequence. In vivo T1 maps and LGE images were acquired with the proposed sequence and quantitatively compared with 2D multislice Modified Look?Locker inversion recovery (MOLLI) T1 maps. Exemplary images in a patient with focal scar were compared with conventional LGE imaging. Results The deviation of the proposed method and the spin?echo reference was? 2014 3D imaging compressed sensing diffused fibrosis LGE imaging myocardial T1 mapping phase sensitive imaging quantitative cardiac MRI Enthalten in Magnetic resonance in medicine New York, NY [u.a.] : Wiley-Liss, 1984 74(2015), 4, Seite 1032-1041 Online-Ressource (DE-627)303257040 (DE-600)1493786-4 (DE-576)096290455 1522-2594 nnns volume:74 year:2015 number:4 pages:1032-1041 extent:10 http://dx.doi.org/10.1002/mrm.25495 Verlag Resolving-System Volltext https://onlinelibrary-wiley-com.ezproxy.medma.uni-heidelberg.de/doi/abs/10.1002/mrm.25495 Verlag Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_266 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 74 2015 4 1032-1041 10 2013 01 DE-16-250 3004392674 00 --%%-- --%%-- --%%-- --%%-- l01 27-03-18 2013 01 DE-16-250 00 s hd2015 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_8 2013 01 DE-16-250 03 s s_10 2013 01 DE-16-250 04 p (DE-627)1477523898 Weingärtner, Sebastian 2013 01 DE-16-250 04 k (DE-627)1430735864 Lehrstuhl für Computerunterstützte Klinische Medizin (CKM) 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_1
spelling	10.1002/mrm.25495 doi (DE-627)1571485058 (DE-576)501485058 (DE-599)BSZ501485058 (OCoLC)1340998410 DE-627 ger DE-627 rda eng Weingärtner, Sebastian 1991- verfasserin (DE-588)1051891507 (DE-627)786975199 (DE-576)407522883 aut Free‐breathing combined three‐dimensional phase sensitive late gadolinium enhancement and T1 mapping for myocardial tissue characterization Weingärtner Sebastian, Akçakaya Mehmet, Roujol Sébastien, Basha Tamer, Tschabrunn Cory, Berg Sophie, Anter Elad, and Nezafat Reza 2015 10 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Published online: 16 October 2014 Gesehen am 27.03.2018 Purpose To develop a novel MR sequence for combined three?dimensional (3D) phase?sensitive (PS) late gadolinium enhancement (LGE) and T1 mapping to allow for simultaneous assessment of focal and diffuse myocardial fibrosis. Methods In the proposed sequence, four 3D imaging volumes are acquired with different T1 weightings using a combined saturation and inversion preparation, after administration of a gadolinium contrast agent. One image is acquired fully sampled with the inversion time selected to null the healthy myocardial signal (the LGE image). The other three images are three?fold under?sampled and reconstructed using compressed sensing. An acquisition scheme with two interleaved imaging cycles and joint navigator?gating of those cycles ensures spatial registration of the imaging volumes. T1 maps are generated using all four imaging volumes. The signal?polarity in the LGE image is restored using supplementary information from the T1 fit to generate PS?LGE images. The accuracy of the proposed method was assessed with respect to a inversion?recovery spin?echo sequence. In vivo T1 maps and LGE images were acquired with the proposed sequence and quantitatively compared with 2D multislice Modified Look?Locker inversion recovery (MOLLI) T1 maps. Exemplary images in a patient with focal scar were compared with conventional LGE imaging. Results The deviation of the proposed method and the spin?echo reference was? 2014 3D imaging compressed sensing diffused fibrosis LGE imaging myocardial T1 mapping phase sensitive imaging quantitative cardiac MRI Enthalten in Magnetic resonance in medicine New York, NY [u.a.] : Wiley-Liss, 1984 74(2015), 4, Seite 1032-1041 Online-Ressource (DE-627)303257040 (DE-600)1493786-4 (DE-576)096290455 1522-2594 nnns volume:74 year:2015 number:4 pages:1032-1041 extent:10 http://dx.doi.org/10.1002/mrm.25495 Verlag Resolving-System Volltext https://onlinelibrary-wiley-com.ezproxy.medma.uni-heidelberg.de/doi/abs/10.1002/mrm.25495 Verlag Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_266 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 74 2015 4 1032-1041 10 2013 01 DE-16-250 3004392674 00 --%%-- --%%-- --%%-- --%%-- l01 27-03-18 2013 01 DE-16-250 00 s hd2015 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_8 2013 01 DE-16-250 03 s s_10 2013 01 DE-16-250 04 p (DE-627)1477523898 Weingärtner, Sebastian 2013 01 DE-16-250 04 k (DE-627)1430735864 Lehrstuhl für Computerunterstützte Klinische Medizin (CKM) 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_1
allfields_unstemmed	10.1002/mrm.25495 doi (DE-627)1571485058 (DE-576)501485058 (DE-599)BSZ501485058 (OCoLC)1340998410 DE-627 ger DE-627 rda eng Weingärtner, Sebastian 1991- verfasserin (DE-588)1051891507 (DE-627)786975199 (DE-576)407522883 aut Free‐breathing combined three‐dimensional phase sensitive late gadolinium enhancement and T1 mapping for myocardial tissue characterization Weingärtner Sebastian, Akçakaya Mehmet, Roujol Sébastien, Basha Tamer, Tschabrunn Cory, Berg Sophie, Anter Elad, and Nezafat Reza 2015 10 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Published online: 16 October 2014 Gesehen am 27.03.2018 Purpose To develop a novel MR sequence for combined three?dimensional (3D) phase?sensitive (PS) late gadolinium enhancement (LGE) and T1 mapping to allow for simultaneous assessment of focal and diffuse myocardial fibrosis. Methods In the proposed sequence, four 3D imaging volumes are acquired with different T1 weightings using a combined saturation and inversion preparation, after administration of a gadolinium contrast agent. One image is acquired fully sampled with the inversion time selected to null the healthy myocardial signal (the LGE image). The other three images are three?fold under?sampled and reconstructed using compressed sensing. An acquisition scheme with two interleaved imaging cycles and joint navigator?gating of those cycles ensures spatial registration of the imaging volumes. T1 maps are generated using all four imaging volumes. The signal?polarity in the LGE image is restored using supplementary information from the T1 fit to generate PS?LGE images. The accuracy of the proposed method was assessed with respect to a inversion?recovery spin?echo sequence. In vivo T1 maps and LGE images were acquired with the proposed sequence and quantitatively compared with 2D multislice Modified Look?Locker inversion recovery (MOLLI) T1 maps. Exemplary images in a patient with focal scar were compared with conventional LGE imaging. Results The deviation of the proposed method and the spin?echo reference was? 2014 3D imaging compressed sensing diffused fibrosis LGE imaging myocardial T1 mapping phase sensitive imaging quantitative cardiac MRI Enthalten in Magnetic resonance in medicine New York, NY [u.a.] : Wiley-Liss, 1984 74(2015), 4, Seite 1032-1041 Online-Ressource (DE-627)303257040 (DE-600)1493786-4 (DE-576)096290455 1522-2594 nnns volume:74 year:2015 number:4 pages:1032-1041 extent:10 http://dx.doi.org/10.1002/mrm.25495 Verlag Resolving-System Volltext https://onlinelibrary-wiley-com.ezproxy.medma.uni-heidelberg.de/doi/abs/10.1002/mrm.25495 Verlag Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_266 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 74 2015 4 1032-1041 10 2013 01 DE-16-250 3004392674 00 --%%-- --%%-- --%%-- --%%-- l01 27-03-18 2013 01 DE-16-250 00 s hd2015 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_8 2013 01 DE-16-250 03 s s_10 2013 01 DE-16-250 04 p (DE-627)1477523898 Weingärtner, Sebastian 2013 01 DE-16-250 04 k (DE-627)1430735864 Lehrstuhl für Computerunterstützte Klinische Medizin (CKM) 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_1
allfieldsGer	10.1002/mrm.25495 doi (DE-627)1571485058 (DE-576)501485058 (DE-599)BSZ501485058 (OCoLC)1340998410 DE-627 ger DE-627 rda eng Weingärtner, Sebastian 1991- verfasserin (DE-588)1051891507 (DE-627)786975199 (DE-576)407522883 aut Free‐breathing combined three‐dimensional phase sensitive late gadolinium enhancement and T1 mapping for myocardial tissue characterization Weingärtner Sebastian, Akçakaya Mehmet, Roujol Sébastien, Basha Tamer, Tschabrunn Cory, Berg Sophie, Anter Elad, and Nezafat Reza 2015 10 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Published online: 16 October 2014 Gesehen am 27.03.2018 Purpose To develop a novel MR sequence for combined three?dimensional (3D) phase?sensitive (PS) late gadolinium enhancement (LGE) and T1 mapping to allow for simultaneous assessment of focal and diffuse myocardial fibrosis. Methods In the proposed sequence, four 3D imaging volumes are acquired with different T1 weightings using a combined saturation and inversion preparation, after administration of a gadolinium contrast agent. One image is acquired fully sampled with the inversion time selected to null the healthy myocardial signal (the LGE image). The other three images are three?fold under?sampled and reconstructed using compressed sensing. An acquisition scheme with two interleaved imaging cycles and joint navigator?gating of those cycles ensures spatial registration of the imaging volumes. T1 maps are generated using all four imaging volumes. The signal?polarity in the LGE image is restored using supplementary information from the T1 fit to generate PS?LGE images. The accuracy of the proposed method was assessed with respect to a inversion?recovery spin?echo sequence. In vivo T1 maps and LGE images were acquired with the proposed sequence and quantitatively compared with 2D multislice Modified Look?Locker inversion recovery (MOLLI) T1 maps. Exemplary images in a patient with focal scar were compared with conventional LGE imaging. Results The deviation of the proposed method and the spin?echo reference was? 2014 3D imaging compressed sensing diffused fibrosis LGE imaging myocardial T1 mapping phase sensitive imaging quantitative cardiac MRI Enthalten in Magnetic resonance in medicine New York, NY [u.a.] : Wiley-Liss, 1984 74(2015), 4, Seite 1032-1041 Online-Ressource (DE-627)303257040 (DE-600)1493786-4 (DE-576)096290455 1522-2594 nnns volume:74 year:2015 number:4 pages:1032-1041 extent:10 http://dx.doi.org/10.1002/mrm.25495 Verlag Resolving-System Volltext https://onlinelibrary-wiley-com.ezproxy.medma.uni-heidelberg.de/doi/abs/10.1002/mrm.25495 Verlag Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_266 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 74 2015 4 1032-1041 10 2013 01 DE-16-250 3004392674 00 --%%-- --%%-- --%%-- --%%-- l01 27-03-18 2013 01 DE-16-250 00 s hd2015 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_8 2013 01 DE-16-250 03 s s_10 2013 01 DE-16-250 04 p (DE-627)1477523898 Weingärtner, Sebastian 2013 01 DE-16-250 04 k (DE-627)1430735864 Lehrstuhl für Computerunterstützte Klinische Medizin (CKM) 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_1
allfieldsSound	10.1002/mrm.25495 doi (DE-627)1571485058 (DE-576)501485058 (DE-599)BSZ501485058 (OCoLC)1340998410 DE-627 ger DE-627 rda eng Weingärtner, Sebastian 1991- verfasserin (DE-588)1051891507 (DE-627)786975199 (DE-576)407522883 aut Free‐breathing combined three‐dimensional phase sensitive late gadolinium enhancement and T1 mapping for myocardial tissue characterization Weingärtner Sebastian, Akçakaya Mehmet, Roujol Sébastien, Basha Tamer, Tschabrunn Cory, Berg Sophie, Anter Elad, and Nezafat Reza 2015 10 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Published online: 16 October 2014 Gesehen am 27.03.2018 Purpose To develop a novel MR sequence for combined three?dimensional (3D) phase?sensitive (PS) late gadolinium enhancement (LGE) and T1 mapping to allow for simultaneous assessment of focal and diffuse myocardial fibrosis. Methods In the proposed sequence, four 3D imaging volumes are acquired with different T1 weightings using a combined saturation and inversion preparation, after administration of a gadolinium contrast agent. One image is acquired fully sampled with the inversion time selected to null the healthy myocardial signal (the LGE image). The other three images are three?fold under?sampled and reconstructed using compressed sensing. An acquisition scheme with two interleaved imaging cycles and joint navigator?gating of those cycles ensures spatial registration of the imaging volumes. T1 maps are generated using all four imaging volumes. The signal?polarity in the LGE image is restored using supplementary information from the T1 fit to generate PS?LGE images. The accuracy of the proposed method was assessed with respect to a inversion?recovery spin?echo sequence. In vivo T1 maps and LGE images were acquired with the proposed sequence and quantitatively compared with 2D multislice Modified Look?Locker inversion recovery (MOLLI) T1 maps. Exemplary images in a patient with focal scar were compared with conventional LGE imaging. Results The deviation of the proposed method and the spin?echo reference was? 2014 3D imaging compressed sensing diffused fibrosis LGE imaging myocardial T1 mapping phase sensitive imaging quantitative cardiac MRI Enthalten in Magnetic resonance in medicine New York, NY [u.a.] : Wiley-Liss, 1984 74(2015), 4, Seite 1032-1041 Online-Ressource (DE-627)303257040 (DE-600)1493786-4 (DE-576)096290455 1522-2594 nnns volume:74 year:2015 number:4 pages:1032-1041 extent:10 http://dx.doi.org/10.1002/mrm.25495 Verlag Resolving-System Volltext https://onlinelibrary-wiley-com.ezproxy.medma.uni-heidelberg.de/doi/abs/10.1002/mrm.25495 Verlag Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_266 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 74 2015 4 1032-1041 10 2013 01 DE-16-250 3004392674 00 --%%-- --%%-- --%%-- --%%-- l01 27-03-18 2013 01 DE-16-250 00 s hd2015 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_8 2013 01 DE-16-250 03 s s_10 2013 01 DE-16-250 04 p (DE-627)1477523898 Weingärtner, Sebastian 2013 01 DE-16-250 04 k (DE-627)1430735864 Lehrstuhl für Computerunterstützte Klinische Medizin (CKM) 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_1
language	English
source	Enthalten in Magnetic resonance in medicine 74(2015), 4, Seite 1032-1041 volume:74 year:2015 number:4 pages:1032-1041 extent:10
sourceStr	Enthalten in Magnetic resonance in medicine 74(2015), 4, Seite 1032-1041 volume:74 year:2015 number:4 pages:1032-1041 extent:10
format_phy_str_mv	Article
building	2013:0
institution	findex.gbv.de
selectbib_iln_str_mv	2013@01
topic_facet	3D imaging compressed sensing diffused fibrosis LGE imaging myocardial T1 mapping phase sensitive imaging quantitative cardiac MRI
sw_local_iln_str_mv	2013:hd2015 DE-16-250:hd2015 2013:wissenschaftlicher Artikel (Zeitschrift) DE-16-250:wissenschaftlicher Artikel (Zeitschrift) 2013:per_8 DE-16-250:per_8 2013:s_10 DE-16-250:s_10 2013:Weingärtner, Sebastian DE-16-250:Weingärtner, Sebastian 2013:Lehrstuhl für Computerunterstützte Klinische Medizin (CKM) DE-16-250:Lehrstuhl für Computerunterstützte Klinische Medizin (CKM) 2013:Verfasser DE-16-250:Verfasser 2013:pos_1 DE-16-250:pos_1
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container_title	Magnetic resonance in medicine
authorswithroles_txt_mv	Weingärtner, Sebastian @@aut@@
publishDateDaySort_date	2015-01-01T00:00:00Z
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language_de	englisch
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Methods In the proposed sequence, four 3D imaging volumes are acquired with different T1 weightings using a combined saturation and inversion preparation, after administration of a gadolinium contrast agent. One image is acquired fully sampled with the inversion time selected to null the healthy myocardial signal (the LGE image). The other three images are three?fold under?sampled and reconstructed using compressed sensing. An acquisition scheme with two interleaved imaging cycles and joint navigator?gating of those cycles ensures spatial registration of the imaging volumes. T1 maps are generated using all four imaging volumes. The signal?polarity in the LGE image is restored using supplementary information from the T1 fit to generate PS?LGE images. The accuracy of the proposed method was assessed with respect to a inversion?recovery spin?echo sequence. In vivo T1 maps and LGE images were acquired with the proposed sequence and quantitatively compared with 2D multislice Modified Look?Locker inversion recovery (MOLLI) T1 maps. Exemplary images in a patient with focal scar were compared with conventional LGE imaging. 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topic_title	2013 01 DE-16-250 00 s hd2015 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_8 2013 01 DE-16-250 03 s s_10 2013 01 DE-16-250 04 p (DE-627)1477523898 Weingärtner, Sebastian 2013 01 DE-16-250 04 k (DE-627)1430735864 Lehrstuhl für Computerunterstützte Klinische Medizin (CKM) 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_1 Free‐breathing combined three‐dimensional phase sensitive late gadolinium enhancement and T1 mapping for myocardial tissue characterization Weingärtner Sebastian, Akçakaya Mehmet, Roujol Sébastien, Basha Tamer, Tschabrunn Cory, Berg Sophie, Anter Elad, and Nezafat Reza 3D imaging compressed sensing diffused fibrosis LGE imaging myocardial T1 mapping phase sensitive imaging quantitative cardiac MRI
topic	misc 3D imaging misc compressed sensing misc diffused fibrosis misc LGE imaging misc myocardial T1 mapping misc phase sensitive imaging misc quantitative cardiac MRI 2013 hd2015 2013 wissenschaftlicher Artikel (Zeitschrift) 2013 per_8 2013 s_10 2013 Weingärtner, Sebastian 2013 Lehrstuhl für Computerunterstützte Klinische Medizin (CKM) 2013 Verfasser 2013 pos_1
topic_unstemmed	misc 3D imaging misc compressed sensing misc diffused fibrosis misc LGE imaging misc myocardial T1 mapping misc phase sensitive imaging misc quantitative cardiac MRI 2013 hd2015 2013 wissenschaftlicher Artikel (Zeitschrift) 2013 per_8 2013 s_10 2013 Weingärtner, Sebastian 2013 Lehrstuhl für Computerunterstützte Klinische Medizin (CKM) 2013 Verfasser 2013 pos_1
topic_browse	misc 3D imaging misc compressed sensing misc diffused fibrosis misc LGE imaging misc myocardial T1 mapping misc phase sensitive imaging misc quantitative cardiac MRI 2013 hd2015 2013 wissenschaftlicher Artikel (Zeitschrift) 2013 per_8 2013 s_10 2013 Weingärtner, Sebastian 2013 Lehrstuhl für Computerunterstützte Klinische Medizin (CKM) 2013 Verfasser 2013 pos_1
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title	Free‐breathing combined three‐dimensional phase sensitive late gadolinium enhancement and T1 mapping for myocardial tissue characterization
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title_full	Free‐breathing combined three‐dimensional phase sensitive late gadolinium enhancement and T1 mapping for myocardial tissue characterization Weingärtner Sebastian, Akçakaya Mehmet, Roujol Sébastien, Basha Tamer, Tschabrunn Cory, Berg Sophie, Anter Elad, and Nezafat Reza
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author-letter	Weingärtner, Sebastian
doi_str_mv	10.1002/mrm.25495
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title_sort	free‐breathing combined three‐dimensional phase sensitive late gadolinium enhancement and t1 mapping for myocardial tissue characterization
title_auth	Free‐breathing combined three‐dimensional phase sensitive late gadolinium enhancement and T1 mapping for myocardial tissue characterization
abstract	Purpose To develop a novel MR sequence for combined three?dimensional (3D) phase?sensitive (PS) late gadolinium enhancement (LGE) and T1 mapping to allow for simultaneous assessment of focal and diffuse myocardial fibrosis. Methods In the proposed sequence, four 3D imaging volumes are acquired with different T1 weightings using a combined saturation and inversion preparation, after administration of a gadolinium contrast agent. One image is acquired fully sampled with the inversion time selected to null the healthy myocardial signal (the LGE image). The other three images are three?fold under?sampled and reconstructed using compressed sensing. An acquisition scheme with two interleaved imaging cycles and joint navigator?gating of those cycles ensures spatial registration of the imaging volumes. T1 maps are generated using all four imaging volumes. The signal?polarity in the LGE image is restored using supplementary information from the T1 fit to generate PS?LGE images. The accuracy of the proposed method was assessed with respect to a inversion?recovery spin?echo sequence. In vivo T1 maps and LGE images were acquired with the proposed sequence and quantitatively compared with 2D multislice Modified Look?Locker inversion recovery (MOLLI) T1 maps. Exemplary images in a patient with focal scar were compared with conventional LGE imaging. Results The deviation of the proposed method and the spin?echo reference was? Published online: 16 October 2014 Gesehen am 27.03.2018
abstractGer	Purpose To develop a novel MR sequence for combined three?dimensional (3D) phase?sensitive (PS) late gadolinium enhancement (LGE) and T1 mapping to allow for simultaneous assessment of focal and diffuse myocardial fibrosis. Methods In the proposed sequence, four 3D imaging volumes are acquired with different T1 weightings using a combined saturation and inversion preparation, after administration of a gadolinium contrast agent. One image is acquired fully sampled with the inversion time selected to null the healthy myocardial signal (the LGE image). The other three images are three?fold under?sampled and reconstructed using compressed sensing. An acquisition scheme with two interleaved imaging cycles and joint navigator?gating of those cycles ensures spatial registration of the imaging volumes. T1 maps are generated using all four imaging volumes. The signal?polarity in the LGE image is restored using supplementary information from the T1 fit to generate PS?LGE images. The accuracy of the proposed method was assessed with respect to a inversion?recovery spin?echo sequence. In vivo T1 maps and LGE images were acquired with the proposed sequence and quantitatively compared with 2D multislice Modified Look?Locker inversion recovery (MOLLI) T1 maps. Exemplary images in a patient with focal scar were compared with conventional LGE imaging. Results The deviation of the proposed method and the spin?echo reference was? Published online: 16 October 2014 Gesehen am 27.03.2018
abstract_unstemmed	Purpose To develop a novel MR sequence for combined three?dimensional (3D) phase?sensitive (PS) late gadolinium enhancement (LGE) and T1 mapping to allow for simultaneous assessment of focal and diffuse myocardial fibrosis. Methods In the proposed sequence, four 3D imaging volumes are acquired with different T1 weightings using a combined saturation and inversion preparation, after administration of a gadolinium contrast agent. One image is acquired fully sampled with the inversion time selected to null the healthy myocardial signal (the LGE image). The other three images are three?fold under?sampled and reconstructed using compressed sensing. An acquisition scheme with two interleaved imaging cycles and joint navigator?gating of those cycles ensures spatial registration of the imaging volumes. T1 maps are generated using all four imaging volumes. The signal?polarity in the LGE image is restored using supplementary information from the T1 fit to generate PS?LGE images. The accuracy of the proposed method was assessed with respect to a inversion?recovery spin?echo sequence. In vivo T1 maps and LGE images were acquired with the proposed sequence and quantitatively compared with 2D multislice Modified Look?Locker inversion recovery (MOLLI) T1 maps. Exemplary images in a patient with focal scar were compared with conventional LGE imaging. Results The deviation of the proposed method and the spin?echo reference was? Published online: 16 October 2014 Gesehen am 27.03.2018
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container_issue	4
title_short	Free‐breathing combined three‐dimensional phase sensitive late gadolinium enhancement and T1 mapping for myocardial tissue characterization
url	http://dx.doi.org/10.1002/mrm.25495 https://onlinelibrary-wiley-com.ezproxy.medma.uni-heidelberg.de/doi/abs/10.1002/mrm.25495
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Free‐breathing combined three‐dimensional phase sensitive late gadolinium enhancement and T1 mapping for myocardial tissue characterization

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