EAACI Guidelines on allergen immunotherapy : IgE-mediated food allergy
Food allergy can result in considerable morbidity, impairment of quality of life, and healthcare expenditure. There is therefore interest in novel strategies for its treatment, particularly food allergen immunotherapy (FA-AIT) through the oral (OIT), sublingual (SLIT), or epicutaneous (EPIT) routes....
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Pajno, Giovanni B. [verfasserIn] Pfaar, Oliver - 1972- [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2018 |
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| Schlagwörter: |
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| Anmerkung: |
Published online: 21 September 2017 Gesehen am 23.05.2018 |
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| Umfang: |
17 |
| Übergeordnetes Werk: |
Enthalten in: Allergy - Oxford : Wiley, 1978, 73(2018), 4, Seite 799-815 |
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| Übergeordnetes Werk: |
volume:73 ; year:2018 ; number:4 ; pages:799-815 ; extent:17 |
| Links: |
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| DOI / URN: |
10.1111/all.13319 |
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| Katalog-ID: |
1575448106 |
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| 520 | |a Food allergy can result in considerable morbidity, impairment of quality of life, and healthcare expenditure. There is therefore interest in novel strategies for its treatment, particularly food allergen immunotherapy (FA-AIT) through the oral (OIT), sublingual (SLIT), or epicutaneous (EPIT) routes. This Guideline, prepared by the European Academy of Allergy and Clinical Immunology (EAACI) Task Force on Allergen Immunotherapy for IgE-mediated Food Allergy, aims to provide evidence-based recommendations for active treatment of IgE-mediated food allergy with FA-AIT. Immunotherapy relies on the delivery of gradually increasing doses of specific allergen to increase the threshold of reaction while on therapy (also known as desensitization) and ultimately to achieve post-discontinuation effectiveness (also known as tolerance or sustained unresponsiveness). Oral FA-AIT has most frequently been assessed: here, the allergen is either immediately swallowed (OIT) or held under the tongue for a period of time (SLIT). Overall, trials have found substantial benefit for patients undergoing either OIT or SLIT with respect to efficacy during treatment, particularly for cow's milk, hen's egg, and peanut allergies. A benefit post-discontinuation is also suggested, but not confirmed. Adverse events during FA-AIT have been frequently reported, but few subjects discontinue FA-AIT as a result of these. Taking into account the current evidence, FA-AIT should only be performed in research centers or in clinical centers with an extensive experience in FA-AIT. Patients and their families should be provided with information about the use of FA-AIT for IgE-mediated food allergy to allow them to make an informed decision about the therapy. | ||
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10.1111/all.13319 doi (DE-627)1575448106 (DE-576)505448106 (DE-599)BSZ505448106 (OCoLC)1341009970 DE-627 ger DE-627 rda eng Pajno, Giovanni B. verfasserin (DE-588)1160000816 (DE-627)1023123827 (DE-576)505448777 aut EAACI Guidelines on allergen immunotherapy IgE-mediated food allergy G. B. Pajno, M. Fernandez‐Rivas, S. Arasi, G. Roberts, C. A. Akdis, M. Alvaro‐Lozano, K. Beyer, C. Bindslev‐Jensen, W. Burks, M. Ebisawa, P. Eigenmann, E. Knol, K. C. Nadeau, L. K. Poulsen, R. van Ree, A. F. Santos, G. du Toit, S. Dhami, U. Nurmatov, Y. Boloh, M. Makela, L. O'Mahony, N. Papadopoulos, C. Sackesen, I. Agache, E. Angier, S. Halken, M. Jutel, S. Lau, O. Pfaar, D. Ryan, G. Sturm, E.-M. Varga, R. G. van Wijk, A. Sheikh, A. Muraro 2018 17 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Published online: 21 September 2017 Gesehen am 23.05.2018 Food allergy can result in considerable morbidity, impairment of quality of life, and healthcare expenditure. There is therefore interest in novel strategies for its treatment, particularly food allergen immunotherapy (FA-AIT) through the oral (OIT), sublingual (SLIT), or epicutaneous (EPIT) routes. This Guideline, prepared by the European Academy of Allergy and Clinical Immunology (EAACI) Task Force on Allergen Immunotherapy for IgE-mediated Food Allergy, aims to provide evidence-based recommendations for active treatment of IgE-mediated food allergy with FA-AIT. Immunotherapy relies on the delivery of gradually increasing doses of specific allergen to increase the threshold of reaction while on therapy (also known as desensitization) and ultimately to achieve post-discontinuation effectiveness (also known as tolerance or sustained unresponsiveness). Oral FA-AIT has most frequently been assessed: here, the allergen is either immediately swallowed (OIT) or held under the tongue for a period of time (SLIT). Overall, trials have found substantial benefit for patients undergoing either OIT or SLIT with respect to efficacy during treatment, particularly for cow's milk, hen's egg, and peanut allergies. A benefit post-discontinuation is also suggested, but not confirmed. Adverse events during FA-AIT have been frequently reported, but few subjects discontinue FA-AIT as a result of these. Taking into account the current evidence, FA-AIT should only be performed in research centers or in clinical centers with an extensive experience in FA-AIT. Patients and their families should be provided with information about the use of FA-AIT for IgE-mediated food allergy to allow them to make an informed decision about the therapy. 2017 adolescent adult allergen immunotherapy allergy food pediatric Pfaar, Oliver 1972- verfasserin (DE-588)12385900X (DE-627)706454049 (DE-576)293913099 aut Enthalten in Allergy Oxford : Wiley, 1978 73(2018), 4, Seite 799-815 Online-Ressource (DE-627)320425428 (DE-600)2003114-2 (DE-576)091140153 1398-9995 nnns volume:73 year:2018 number:4 pages:799-815 extent:17 http://dx.doi.org/10.1111/all.13319 Verlag Resolving-System Volltext https://onlinelibrary.wiley.com/doi/abs/10.1111/all.13319 Verlag Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_266 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 73 2018 4 799-815 17 2013 01 DE-16-250 3010009755 00 --%%-- --%%-- --%%-- --%%-- l01 23-05-18 2013 01 DE-16-250 00 s hd2018 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_36 2013 01 DE-16-250 03 s s_17 2013 01 DE-16-250 04 p (DE-627)1482044870 Pfaar, Oliver 2013 01 DE-16-250 04 k (DE-627)158397606X Klinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_30 |
| spelling |
10.1111/all.13319 doi (DE-627)1575448106 (DE-576)505448106 (DE-599)BSZ505448106 (OCoLC)1341009970 DE-627 ger DE-627 rda eng Pajno, Giovanni B. verfasserin (DE-588)1160000816 (DE-627)1023123827 (DE-576)505448777 aut EAACI Guidelines on allergen immunotherapy IgE-mediated food allergy G. B. Pajno, M. Fernandez‐Rivas, S. Arasi, G. Roberts, C. A. Akdis, M. Alvaro‐Lozano, K. Beyer, C. Bindslev‐Jensen, W. Burks, M. Ebisawa, P. Eigenmann, E. Knol, K. C. Nadeau, L. K. Poulsen, R. van Ree, A. F. Santos, G. du Toit, S. Dhami, U. Nurmatov, Y. Boloh, M. Makela, L. O'Mahony, N. Papadopoulos, C. Sackesen, I. Agache, E. Angier, S. Halken, M. Jutel, S. Lau, O. Pfaar, D. Ryan, G. Sturm, E.-M. Varga, R. G. van Wijk, A. Sheikh, A. Muraro 2018 17 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Published online: 21 September 2017 Gesehen am 23.05.2018 Food allergy can result in considerable morbidity, impairment of quality of life, and healthcare expenditure. There is therefore interest in novel strategies for its treatment, particularly food allergen immunotherapy (FA-AIT) through the oral (OIT), sublingual (SLIT), or epicutaneous (EPIT) routes. This Guideline, prepared by the European Academy of Allergy and Clinical Immunology (EAACI) Task Force on Allergen Immunotherapy for IgE-mediated Food Allergy, aims to provide evidence-based recommendations for active treatment of IgE-mediated food allergy with FA-AIT. Immunotherapy relies on the delivery of gradually increasing doses of specific allergen to increase the threshold of reaction while on therapy (also known as desensitization) and ultimately to achieve post-discontinuation effectiveness (also known as tolerance or sustained unresponsiveness). Oral FA-AIT has most frequently been assessed: here, the allergen is either immediately swallowed (OIT) or held under the tongue for a period of time (SLIT). Overall, trials have found substantial benefit for patients undergoing either OIT or SLIT with respect to efficacy during treatment, particularly for cow's milk, hen's egg, and peanut allergies. A benefit post-discontinuation is also suggested, but not confirmed. Adverse events during FA-AIT have been frequently reported, but few subjects discontinue FA-AIT as a result of these. Taking into account the current evidence, FA-AIT should only be performed in research centers or in clinical centers with an extensive experience in FA-AIT. Patients and their families should be provided with information about the use of FA-AIT for IgE-mediated food allergy to allow them to make an informed decision about the therapy. 2017 adolescent adult allergen immunotherapy allergy food pediatric Pfaar, Oliver 1972- verfasserin (DE-588)12385900X (DE-627)706454049 (DE-576)293913099 aut Enthalten in Allergy Oxford : Wiley, 1978 73(2018), 4, Seite 799-815 Online-Ressource (DE-627)320425428 (DE-600)2003114-2 (DE-576)091140153 1398-9995 nnns volume:73 year:2018 number:4 pages:799-815 extent:17 http://dx.doi.org/10.1111/all.13319 Verlag Resolving-System Volltext https://onlinelibrary.wiley.com/doi/abs/10.1111/all.13319 Verlag Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_266 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 73 2018 4 799-815 17 2013 01 DE-16-250 3010009755 00 --%%-- --%%-- --%%-- --%%-- l01 23-05-18 2013 01 DE-16-250 00 s hd2018 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_36 2013 01 DE-16-250 03 s s_17 2013 01 DE-16-250 04 p (DE-627)1482044870 Pfaar, Oliver 2013 01 DE-16-250 04 k (DE-627)158397606X Klinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_30 |
| allfields_unstemmed |
10.1111/all.13319 doi (DE-627)1575448106 (DE-576)505448106 (DE-599)BSZ505448106 (OCoLC)1341009970 DE-627 ger DE-627 rda eng Pajno, Giovanni B. verfasserin (DE-588)1160000816 (DE-627)1023123827 (DE-576)505448777 aut EAACI Guidelines on allergen immunotherapy IgE-mediated food allergy G. B. Pajno, M. Fernandez‐Rivas, S. Arasi, G. Roberts, C. A. Akdis, M. Alvaro‐Lozano, K. Beyer, C. Bindslev‐Jensen, W. Burks, M. Ebisawa, P. Eigenmann, E. Knol, K. C. Nadeau, L. K. Poulsen, R. van Ree, A. F. Santos, G. du Toit, S. Dhami, U. Nurmatov, Y. Boloh, M. Makela, L. O'Mahony, N. Papadopoulos, C. Sackesen, I. Agache, E. Angier, S. Halken, M. Jutel, S. Lau, O. Pfaar, D. Ryan, G. Sturm, E.-M. Varga, R. G. van Wijk, A. Sheikh, A. Muraro 2018 17 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Published online: 21 September 2017 Gesehen am 23.05.2018 Food allergy can result in considerable morbidity, impairment of quality of life, and healthcare expenditure. There is therefore interest in novel strategies for its treatment, particularly food allergen immunotherapy (FA-AIT) through the oral (OIT), sublingual (SLIT), or epicutaneous (EPIT) routes. This Guideline, prepared by the European Academy of Allergy and Clinical Immunology (EAACI) Task Force on Allergen Immunotherapy for IgE-mediated Food Allergy, aims to provide evidence-based recommendations for active treatment of IgE-mediated food allergy with FA-AIT. Immunotherapy relies on the delivery of gradually increasing doses of specific allergen to increase the threshold of reaction while on therapy (also known as desensitization) and ultimately to achieve post-discontinuation effectiveness (also known as tolerance or sustained unresponsiveness). Oral FA-AIT has most frequently been assessed: here, the allergen is either immediately swallowed (OIT) or held under the tongue for a period of time (SLIT). Overall, trials have found substantial benefit for patients undergoing either OIT or SLIT with respect to efficacy during treatment, particularly for cow's milk, hen's egg, and peanut allergies. A benefit post-discontinuation is also suggested, but not confirmed. Adverse events during FA-AIT have been frequently reported, but few subjects discontinue FA-AIT as a result of these. Taking into account the current evidence, FA-AIT should only be performed in research centers or in clinical centers with an extensive experience in FA-AIT. Patients and their families should be provided with information about the use of FA-AIT for IgE-mediated food allergy to allow them to make an informed decision about the therapy. 2017 adolescent adult allergen immunotherapy allergy food pediatric Pfaar, Oliver 1972- verfasserin (DE-588)12385900X (DE-627)706454049 (DE-576)293913099 aut Enthalten in Allergy Oxford : Wiley, 1978 73(2018), 4, Seite 799-815 Online-Ressource (DE-627)320425428 (DE-600)2003114-2 (DE-576)091140153 1398-9995 nnns volume:73 year:2018 number:4 pages:799-815 extent:17 http://dx.doi.org/10.1111/all.13319 Verlag Resolving-System Volltext https://onlinelibrary.wiley.com/doi/abs/10.1111/all.13319 Verlag Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_266 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 73 2018 4 799-815 17 2013 01 DE-16-250 3010009755 00 --%%-- --%%-- --%%-- --%%-- l01 23-05-18 2013 01 DE-16-250 00 s hd2018 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_36 2013 01 DE-16-250 03 s s_17 2013 01 DE-16-250 04 p (DE-627)1482044870 Pfaar, Oliver 2013 01 DE-16-250 04 k (DE-627)158397606X Klinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_30 |
| allfieldsGer |
10.1111/all.13319 doi (DE-627)1575448106 (DE-576)505448106 (DE-599)BSZ505448106 (OCoLC)1341009970 DE-627 ger DE-627 rda eng Pajno, Giovanni B. verfasserin (DE-588)1160000816 (DE-627)1023123827 (DE-576)505448777 aut EAACI Guidelines on allergen immunotherapy IgE-mediated food allergy G. B. Pajno, M. Fernandez‐Rivas, S. Arasi, G. Roberts, C. A. Akdis, M. Alvaro‐Lozano, K. Beyer, C. Bindslev‐Jensen, W. Burks, M. Ebisawa, P. Eigenmann, E. Knol, K. C. Nadeau, L. K. Poulsen, R. van Ree, A. F. Santos, G. du Toit, S. Dhami, U. Nurmatov, Y. Boloh, M. Makela, L. O'Mahony, N. Papadopoulos, C. Sackesen, I. Agache, E. Angier, S. Halken, M. Jutel, S. Lau, O. Pfaar, D. Ryan, G. Sturm, E.-M. Varga, R. G. van Wijk, A. Sheikh, A. Muraro 2018 17 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Published online: 21 September 2017 Gesehen am 23.05.2018 Food allergy can result in considerable morbidity, impairment of quality of life, and healthcare expenditure. There is therefore interest in novel strategies for its treatment, particularly food allergen immunotherapy (FA-AIT) through the oral (OIT), sublingual (SLIT), or epicutaneous (EPIT) routes. This Guideline, prepared by the European Academy of Allergy and Clinical Immunology (EAACI) Task Force on Allergen Immunotherapy for IgE-mediated Food Allergy, aims to provide evidence-based recommendations for active treatment of IgE-mediated food allergy with FA-AIT. Immunotherapy relies on the delivery of gradually increasing doses of specific allergen to increase the threshold of reaction while on therapy (also known as desensitization) and ultimately to achieve post-discontinuation effectiveness (also known as tolerance or sustained unresponsiveness). Oral FA-AIT has most frequently been assessed: here, the allergen is either immediately swallowed (OIT) or held under the tongue for a period of time (SLIT). Overall, trials have found substantial benefit for patients undergoing either OIT or SLIT with respect to efficacy during treatment, particularly for cow's milk, hen's egg, and peanut allergies. A benefit post-discontinuation is also suggested, but not confirmed. Adverse events during FA-AIT have been frequently reported, but few subjects discontinue FA-AIT as a result of these. Taking into account the current evidence, FA-AIT should only be performed in research centers or in clinical centers with an extensive experience in FA-AIT. Patients and their families should be provided with information about the use of FA-AIT for IgE-mediated food allergy to allow them to make an informed decision about the therapy. 2017 adolescent adult allergen immunotherapy allergy food pediatric Pfaar, Oliver 1972- verfasserin (DE-588)12385900X (DE-627)706454049 (DE-576)293913099 aut Enthalten in Allergy Oxford : Wiley, 1978 73(2018), 4, Seite 799-815 Online-Ressource (DE-627)320425428 (DE-600)2003114-2 (DE-576)091140153 1398-9995 nnns volume:73 year:2018 number:4 pages:799-815 extent:17 http://dx.doi.org/10.1111/all.13319 Verlag Resolving-System Volltext https://onlinelibrary.wiley.com/doi/abs/10.1111/all.13319 Verlag Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_266 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 73 2018 4 799-815 17 2013 01 DE-16-250 3010009755 00 --%%-- --%%-- --%%-- --%%-- l01 23-05-18 2013 01 DE-16-250 00 s hd2018 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_36 2013 01 DE-16-250 03 s s_17 2013 01 DE-16-250 04 p (DE-627)1482044870 Pfaar, Oliver 2013 01 DE-16-250 04 k (DE-627)158397606X Klinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_30 |
| allfieldsSound |
10.1111/all.13319 doi (DE-627)1575448106 (DE-576)505448106 (DE-599)BSZ505448106 (OCoLC)1341009970 DE-627 ger DE-627 rda eng Pajno, Giovanni B. verfasserin (DE-588)1160000816 (DE-627)1023123827 (DE-576)505448777 aut EAACI Guidelines on allergen immunotherapy IgE-mediated food allergy G. B. Pajno, M. Fernandez‐Rivas, S. Arasi, G. Roberts, C. A. Akdis, M. Alvaro‐Lozano, K. Beyer, C. Bindslev‐Jensen, W. Burks, M. Ebisawa, P. Eigenmann, E. Knol, K. C. Nadeau, L. K. Poulsen, R. van Ree, A. F. Santos, G. du Toit, S. Dhami, U. Nurmatov, Y. Boloh, M. Makela, L. O'Mahony, N. Papadopoulos, C. Sackesen, I. Agache, E. Angier, S. Halken, M. Jutel, S. Lau, O. Pfaar, D. Ryan, G. Sturm, E.-M. Varga, R. G. van Wijk, A. Sheikh, A. Muraro 2018 17 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Published online: 21 September 2017 Gesehen am 23.05.2018 Food allergy can result in considerable morbidity, impairment of quality of life, and healthcare expenditure. There is therefore interest in novel strategies for its treatment, particularly food allergen immunotherapy (FA-AIT) through the oral (OIT), sublingual (SLIT), or epicutaneous (EPIT) routes. This Guideline, prepared by the European Academy of Allergy and Clinical Immunology (EAACI) Task Force on Allergen Immunotherapy for IgE-mediated Food Allergy, aims to provide evidence-based recommendations for active treatment of IgE-mediated food allergy with FA-AIT. Immunotherapy relies on the delivery of gradually increasing doses of specific allergen to increase the threshold of reaction while on therapy (also known as desensitization) and ultimately to achieve post-discontinuation effectiveness (also known as tolerance or sustained unresponsiveness). Oral FA-AIT has most frequently been assessed: here, the allergen is either immediately swallowed (OIT) or held under the tongue for a period of time (SLIT). Overall, trials have found substantial benefit for patients undergoing either OIT or SLIT with respect to efficacy during treatment, particularly for cow's milk, hen's egg, and peanut allergies. A benefit post-discontinuation is also suggested, but not confirmed. Adverse events during FA-AIT have been frequently reported, but few subjects discontinue FA-AIT as a result of these. Taking into account the current evidence, FA-AIT should only be performed in research centers or in clinical centers with an extensive experience in FA-AIT. 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EAACI Guidelines on allergen immunotherapy IgE-mediated food allergy G. B. Pajno, M. Fernandez‐Rivas, S. Arasi, G. Roberts, C. A. Akdis, M. Alvaro‐Lozano, K. Beyer, C. Bindslev‐Jensen, W. Burks, M. Ebisawa, P. Eigenmann, E. Knol, K. C. Nadeau, L. K. Poulsen, R. van Ree, A. F. Santos, G. du Toit, S. Dhami, U. Nurmatov, Y. Boloh, M. Makela, L. O'Mahony, N. Papadopoulos, C. Sackesen, I. Agache, E. Angier, S. Halken, M. Jutel, S. Lau, O. Pfaar, D. Ryan, G. Sturm, E.-M. Varga, R. G. van Wijk, A. Sheikh, A. Muraro |
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EAACI Guidelines on allergen immunotherapy IgE-mediated food allergy |
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Food allergy can result in considerable morbidity, impairment of quality of life, and healthcare expenditure. There is therefore interest in novel strategies for its treatment, particularly food allergen immunotherapy (FA-AIT) through the oral (OIT), sublingual (SLIT), or epicutaneous (EPIT) routes. This Guideline, prepared by the European Academy of Allergy and Clinical Immunology (EAACI) Task Force on Allergen Immunotherapy for IgE-mediated Food Allergy, aims to provide evidence-based recommendations for active treatment of IgE-mediated food allergy with FA-AIT. Immunotherapy relies on the delivery of gradually increasing doses of specific allergen to increase the threshold of reaction while on therapy (also known as desensitization) and ultimately to achieve post-discontinuation effectiveness (also known as tolerance or sustained unresponsiveness). Oral FA-AIT has most frequently been assessed: here, the allergen is either immediately swallowed (OIT) or held under the tongue for a period of time (SLIT). Overall, trials have found substantial benefit for patients undergoing either OIT or SLIT with respect to efficacy during treatment, particularly for cow's milk, hen's egg, and peanut allergies. A benefit post-discontinuation is also suggested, but not confirmed. Adverse events during FA-AIT have been frequently reported, but few subjects discontinue FA-AIT as a result of these. Taking into account the current evidence, FA-AIT should only be performed in research centers or in clinical centers with an extensive experience in FA-AIT. Patients and their families should be provided with information about the use of FA-AIT for IgE-mediated food allergy to allow them to make an informed decision about the therapy. Published online: 21 September 2017 Gesehen am 23.05.2018 |
| abstractGer |
Food allergy can result in considerable morbidity, impairment of quality of life, and healthcare expenditure. There is therefore interest in novel strategies for its treatment, particularly food allergen immunotherapy (FA-AIT) through the oral (OIT), sublingual (SLIT), or epicutaneous (EPIT) routes. This Guideline, prepared by the European Academy of Allergy and Clinical Immunology (EAACI) Task Force on Allergen Immunotherapy for IgE-mediated Food Allergy, aims to provide evidence-based recommendations for active treatment of IgE-mediated food allergy with FA-AIT. Immunotherapy relies on the delivery of gradually increasing doses of specific allergen to increase the threshold of reaction while on therapy (also known as desensitization) and ultimately to achieve post-discontinuation effectiveness (also known as tolerance or sustained unresponsiveness). Oral FA-AIT has most frequently been assessed: here, the allergen is either immediately swallowed (OIT) or held under the tongue for a period of time (SLIT). Overall, trials have found substantial benefit for patients undergoing either OIT or SLIT with respect to efficacy during treatment, particularly for cow's milk, hen's egg, and peanut allergies. A benefit post-discontinuation is also suggested, but not confirmed. Adverse events during FA-AIT have been frequently reported, but few subjects discontinue FA-AIT as a result of these. Taking into account the current evidence, FA-AIT should only be performed in research centers or in clinical centers with an extensive experience in FA-AIT. Patients and their families should be provided with information about the use of FA-AIT for IgE-mediated food allergy to allow them to make an informed decision about the therapy. Published online: 21 September 2017 Gesehen am 23.05.2018 |
| abstract_unstemmed |
Food allergy can result in considerable morbidity, impairment of quality of life, and healthcare expenditure. There is therefore interest in novel strategies for its treatment, particularly food allergen immunotherapy (FA-AIT) through the oral (OIT), sublingual (SLIT), or epicutaneous (EPIT) routes. This Guideline, prepared by the European Academy of Allergy and Clinical Immunology (EAACI) Task Force on Allergen Immunotherapy for IgE-mediated Food Allergy, aims to provide evidence-based recommendations for active treatment of IgE-mediated food allergy with FA-AIT. Immunotherapy relies on the delivery of gradually increasing doses of specific allergen to increase the threshold of reaction while on therapy (also known as desensitization) and ultimately to achieve post-discontinuation effectiveness (also known as tolerance or sustained unresponsiveness). Oral FA-AIT has most frequently been assessed: here, the allergen is either immediately swallowed (OIT) or held under the tongue for a period of time (SLIT). Overall, trials have found substantial benefit for patients undergoing either OIT or SLIT with respect to efficacy during treatment, particularly for cow's milk, hen's egg, and peanut allergies. A benefit post-discontinuation is also suggested, but not confirmed. Adverse events during FA-AIT have been frequently reported, but few subjects discontinue FA-AIT as a result of these. Taking into account the current evidence, FA-AIT should only be performed in research centers or in clinical centers with an extensive experience in FA-AIT. Patients and their families should be provided with information about the use of FA-AIT for IgE-mediated food allergy to allow them to make an informed decision about the therapy. Published online: 21 September 2017 Gesehen am 23.05.2018 |
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B. Pajno, M. Fernandez‐Rivas, S. Arasi, G. Roberts, C. A. Akdis, M. Alvaro‐Lozano, K. Beyer, C. Bindslev‐Jensen, W. Burks, M. Ebisawa, P. Eigenmann, E. Knol, K. C. Nadeau, L. K. Poulsen, R. van Ree, A. F. Santos, G. du Toit, S. Dhami, U. Nurmatov, Y. Boloh, M. Makela, L. O'Mahony, N. Papadopoulos, C. Sackesen, I. Agache, E. Angier, S. Halken, M. Jutel, S. Lau, O. Pfaar, D. Ryan, G. Sturm, E.-M. Varga, R. G. van Wijk, A. Sheikh, A. 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| score |
7.398509 |