Prevention of carcinogenesis and metastasis by artemisinin-type drugs

Artemisia annua (sweet wormwood, qinhao) is an ancient Chinese herbal remedy for pyrexia. Nowadays, artemisinin (qinghaosu) and its derivatives belong to the standard therapies against malaria worldwide, and its discovery has led to the Nobel Prize in Physiology and Medicine to Youyou Tu in 2015. Wh...
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Autor*in:	Abba, Mohammed L. - 1974- [verfasserIn] Patil, Nitin - 1976- [verfasserIn] Leupold, Jörg - 1969- [verfasserIn] Allgayer, Heike - 1969- [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	8 May 2018

Schlagwörter:	Cancer Carcinogenesis Initation L. Metastasis Prevention Progression

Anmerkung:	Gesehen am 02.04.2019
Umfang:	8

Übergeordnetes Werk:	Enthalten in: Cancer letters - Amsterdam [u.a.] : Elsevier Science, 1975, 429(2018), Seite 11-18
Übergeordnetes Werk:	volume:429 ; year:2018 ; pages:11-18 ; extent:8

Links:	Volltext Volltext

DOI / URN:	10.1016/j.canlet.2018.05.008

Katalog-ID:	166270271X

Internformat


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520			\|a Artemisia annua (sweet wormwood, qinhao) is an ancient Chinese herbal remedy for pyrexia. Nowadays, artemisinin (qinghaosu) and its derivatives belong to the standard therapies against malaria worldwide, and its discovery has led to the Nobel Prize in Physiology and Medicine to Youyou Tu in 2015. While most attention has been paid to the treatment of malaria, there is increasing evidence that Artemisinin-type drugs bear a considerable potential to treat and prevent cancer. Rather than reporting on therapy of cancer, this review gives a comprehensive and timely overview on the chemopreventive effects of artemisinin and its derivatives against carcinogenesis and metastasis formation, following the multistage model of carcinogenesis (initiation, promotion, progression). The favorable toxicity profile known from malaria studies indicates that artemisinin-type drugs may be safely applied to prevent carcinogenesis and cancer metastasis in human beings.
650		4	\|a Cancer
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650		4	\|a Initation
650		4	\|a L.
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912			\|a GBV_ILN_31
912			\|a GBV_ILN_32
912			\|a GBV_ILN_40
912			\|a GBV_ILN_60
912			\|a GBV_ILN_62
912			\|a GBV_ILN_63
912			\|a GBV_ILN_65
912			\|a GBV_ILN_69
912			\|a GBV_ILN_70
912			\|a GBV_ILN_73
912			\|a GBV_ILN_74
912			\|a GBV_ILN_90
912			\|a GBV_ILN_95
912			\|a GBV_ILN_100
912			\|a GBV_ILN_101
912			\|a GBV_ILN_105
912			\|a GBV_ILN_110
912			\|a GBV_ILN_151
912			\|a GBV_ILN_224
912			\|a GBV_ILN_370
912			\|a GBV_ILN_602
912			\|a GBV_ILN_702
912			\|a GBV_ILN_2003
912			\|a GBV_ILN_2004
912			\|a GBV_ILN_2005
912			\|a GBV_ILN_2011
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_2015
912			\|a GBV_ILN_2020
912			\|a GBV_ILN_2021
912			\|a GBV_ILN_2025
912			\|a GBV_ILN_2027
912			\|a GBV_ILN_2034
912			\|a GBV_ILN_2038
912			\|a GBV_ILN_2044
912			\|a GBV_ILN_2048
912			\|a GBV_ILN_2049
912			\|a GBV_ILN_2050
912			\|a GBV_ILN_2056
912			\|a GBV_ILN_2059
912			\|a GBV_ILN_2061
912			\|a GBV_ILN_2064
912			\|a GBV_ILN_2065
912			\|a GBV_ILN_2068
912			\|a GBV_ILN_2111
912			\|a GBV_ILN_2112
912			\|a GBV_ILN_2113
912			\|a GBV_ILN_2118
912			\|a GBV_ILN_2122
912			\|a GBV_ILN_2129
912			\|a GBV_ILN_2143
912			\|a GBV_ILN_2147
912			\|a GBV_ILN_2148
912			\|a GBV_ILN_2152
912			\|a GBV_ILN_2153
912			\|a GBV_ILN_2190
912			\|a GBV_ILN_2336
912			\|a GBV_ILN_2507
912			\|a GBV_ILN_2522
912			\|a GBV_ILN_4035
912			\|a GBV_ILN_4037
912			\|a GBV_ILN_4112
912			\|a GBV_ILN_4125
912			\|a GBV_ILN_4126
912			\|a GBV_ILN_4242
912			\|a GBV_ILN_4251
912			\|a GBV_ILN_4305
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4326
912			\|a GBV_ILN_4333
912			\|a GBV_ILN_4334
912			\|a GBV_ILN_4335
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4393
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Indexfelder

author_variant	m l a ml mla n p np j l jl h a ha
matchkey_str	article:18727980:2018----::rvninfacngnssnmtsaibat
oclc_num	1341205881
hierarchy_sort_str	8 May 2018
publishDate	2018
allfields	10.1016/j.canlet.2018.05.008 doi (DE-627)166270271X (DE-599)KXP166270271X (OCoLC)1341205881 DE-627 ger DE-627 rda eng Abba, Mohammed L. 1974- verfasserin (DE-588)1024986101 (DE-627)720854369 (DE-576)369801407 aut Prevention of carcinogenesis and metastasis by artemisinin-type drugs Mohammed L. Abba, Nitin Patil, Jörg Hendrik Leupold, Mohamed E.M. Saeed, Thomas Efferth, Heike Allgayer 8 May 2018 8 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Gesehen am 02.04.2019 Artemisia annua (sweet wormwood, qinhao) is an ancient Chinese herbal remedy for pyrexia. Nowadays, artemisinin (qinghaosu) and its derivatives belong to the standard therapies against malaria worldwide, and its discovery has led to the Nobel Prize in Physiology and Medicine to Youyou Tu in 2015. While most attention has been paid to the treatment of malaria, there is increasing evidence that Artemisinin-type drugs bear a considerable potential to treat and prevent cancer. Rather than reporting on therapy of cancer, this review gives a comprehensive and timely overview on the chemopreventive effects of artemisinin and its derivatives against carcinogenesis and metastasis formation, following the multistage model of carcinogenesis (initiation, promotion, progression). The favorable toxicity profile known from malaria studies indicates that artemisinin-type drugs may be safely applied to prevent carcinogenesis and cancer metastasis in human beings. Cancer Carcinogenesis Initation L. Metastasis Prevention Progression Patil, Nitin 1976- verfasserin (DE-588)1031802177 (DE-627)747795371 (DE-576)379534622 aut Leupold, Jörg 1969- verfasserin (DE-588)130056030 (DE-627)488795796 (DE-576)29797310X aut Allgayer, Heike 1969- verfasserin (DE-588)1024987884 (DE-627)720854466 (DE-576)369805003 aut Enthalten in Cancer letters Amsterdam [u.a.] : Elsevier Science, 1975 429(2018), Seite 11-18 Online-Ressource (DE-627)320434796 (DE-600)2004212-7 (DE-576)261677926 1872-7980 nnns volume:429 year:2018 pages:11-18 extent:8 https://doi.org/10.1016/j.canlet.2018.05.008 Verlag Resolving-System Volltext http://www.sciencedirect.com/science/article/pii/S0304383518303276 Verlag Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 AR 429 2018 11-18 8 2013 01 DE-16-250 3417702046 00 --%%-- --%%-- --%%-- --%%-- l01 02-04-19 2013 01 DE-16-250 00 s hd2018 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_6 2013 01 DE-16-250 03 s s_8 2013 01 DE-16-250 04 p (DE-627)1439807345 Abba, Mohammed L. 2013 01 DE-16-250 04 k (DE-627)1416468528 III. Medizinische Klinik 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_1 2013 01 DE-16-250 05 p (DE-627)1524969370 Patil, Nitin 2013 01 DE-16-250 05 k (DE-627)1416469214 Zentrum für Biomedizin und Medizintechnik Mannheim (CBTM) 2013 01 DE-16-250 05 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 05 s pos_2 2013 01 DE-16-250 06 p (DE-627)1451500963 Leupold, Jörg 2013 01 DE-16-250 06 k (DE-627)1416469214 Zentrum für Biomedizin und Medizintechnik Mannheim (CBTM) 2013 01 DE-16-250 06 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 06 s pos_3 2013 01 DE-16-250 07 p (DE-627)1439807183 Allgayer, Heike 2013 01 DE-16-250 07 k (DE-627)1416469214 Zentrum für Biomedizin und Medizintechnik Mannheim (CBTM) 2013 01 DE-16-250 07 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 07 s pos_6
spelling	10.1016/j.canlet.2018.05.008 doi (DE-627)166270271X (DE-599)KXP166270271X (OCoLC)1341205881 DE-627 ger DE-627 rda eng Abba, Mohammed L. 1974- verfasserin (DE-588)1024986101 (DE-627)720854369 (DE-576)369801407 aut Prevention of carcinogenesis and metastasis by artemisinin-type drugs Mohammed L. Abba, Nitin Patil, Jörg Hendrik Leupold, Mohamed E.M. Saeed, Thomas Efferth, Heike Allgayer 8 May 2018 8 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Gesehen am 02.04.2019 Artemisia annua (sweet wormwood, qinhao) is an ancient Chinese herbal remedy for pyrexia. Nowadays, artemisinin (qinghaosu) and its derivatives belong to the standard therapies against malaria worldwide, and its discovery has led to the Nobel Prize in Physiology and Medicine to Youyou Tu in 2015. While most attention has been paid to the treatment of malaria, there is increasing evidence that Artemisinin-type drugs bear a considerable potential to treat and prevent cancer. Rather than reporting on therapy of cancer, this review gives a comprehensive and timely overview on the chemopreventive effects of artemisinin and its derivatives against carcinogenesis and metastasis formation, following the multistage model of carcinogenesis (initiation, promotion, progression). The favorable toxicity profile known from malaria studies indicates that artemisinin-type drugs may be safely applied to prevent carcinogenesis and cancer metastasis in human beings. Cancer Carcinogenesis Initation L. Metastasis Prevention Progression Patil, Nitin 1976- verfasserin (DE-588)1031802177 (DE-627)747795371 (DE-576)379534622 aut Leupold, Jörg 1969- verfasserin (DE-588)130056030 (DE-627)488795796 (DE-576)29797310X aut Allgayer, Heike 1969- verfasserin (DE-588)1024987884 (DE-627)720854466 (DE-576)369805003 aut Enthalten in Cancer letters Amsterdam [u.a.] : Elsevier Science, 1975 429(2018), Seite 11-18 Online-Ressource (DE-627)320434796 (DE-600)2004212-7 (DE-576)261677926 1872-7980 nnns volume:429 year:2018 pages:11-18 extent:8 https://doi.org/10.1016/j.canlet.2018.05.008 Verlag Resolving-System Volltext http://www.sciencedirect.com/science/article/pii/S0304383518303276 Verlag Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 AR 429 2018 11-18 8 2013 01 DE-16-250 3417702046 00 --%%-- --%%-- --%%-- --%%-- l01 02-04-19 2013 01 DE-16-250 00 s hd2018 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_6 2013 01 DE-16-250 03 s s_8 2013 01 DE-16-250 04 p (DE-627)1439807345 Abba, Mohammed L. 2013 01 DE-16-250 04 k (DE-627)1416468528 III. Medizinische Klinik 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_1 2013 01 DE-16-250 05 p (DE-627)1524969370 Patil, Nitin 2013 01 DE-16-250 05 k (DE-627)1416469214 Zentrum für Biomedizin und Medizintechnik Mannheim (CBTM) 2013 01 DE-16-250 05 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 05 s pos_2 2013 01 DE-16-250 06 p (DE-627)1451500963 Leupold, Jörg 2013 01 DE-16-250 06 k (DE-627)1416469214 Zentrum für Biomedizin und Medizintechnik Mannheim (CBTM) 2013 01 DE-16-250 06 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 06 s pos_3 2013 01 DE-16-250 07 p (DE-627)1439807183 Allgayer, Heike 2013 01 DE-16-250 07 k (DE-627)1416469214 Zentrum für Biomedizin und Medizintechnik Mannheim (CBTM) 2013 01 DE-16-250 07 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 07 s pos_6
allfields_unstemmed	10.1016/j.canlet.2018.05.008 doi (DE-627)166270271X (DE-599)KXP166270271X (OCoLC)1341205881 DE-627 ger DE-627 rda eng Abba, Mohammed L. 1974- verfasserin (DE-588)1024986101 (DE-627)720854369 (DE-576)369801407 aut Prevention of carcinogenesis and metastasis by artemisinin-type drugs Mohammed L. Abba, Nitin Patil, Jörg Hendrik Leupold, Mohamed E.M. Saeed, Thomas Efferth, Heike Allgayer 8 May 2018 8 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Gesehen am 02.04.2019 Artemisia annua (sweet wormwood, qinhao) is an ancient Chinese herbal remedy for pyrexia. Nowadays, artemisinin (qinghaosu) and its derivatives belong to the standard therapies against malaria worldwide, and its discovery has led to the Nobel Prize in Physiology and Medicine to Youyou Tu in 2015. While most attention has been paid to the treatment of malaria, there is increasing evidence that Artemisinin-type drugs bear a considerable potential to treat and prevent cancer. Rather than reporting on therapy of cancer, this review gives a comprehensive and timely overview on the chemopreventive effects of artemisinin and its derivatives against carcinogenesis and metastasis formation, following the multistage model of carcinogenesis (initiation, promotion, progression). The favorable toxicity profile known from malaria studies indicates that artemisinin-type drugs may be safely applied to prevent carcinogenesis and cancer metastasis in human beings. Cancer Carcinogenesis Initation L. Metastasis Prevention Progression Patil, Nitin 1976- verfasserin (DE-588)1031802177 (DE-627)747795371 (DE-576)379534622 aut Leupold, Jörg 1969- verfasserin (DE-588)130056030 (DE-627)488795796 (DE-576)29797310X aut Allgayer, Heike 1969- verfasserin (DE-588)1024987884 (DE-627)720854466 (DE-576)369805003 aut Enthalten in Cancer letters Amsterdam [u.a.] : Elsevier Science, 1975 429(2018), Seite 11-18 Online-Ressource (DE-627)320434796 (DE-600)2004212-7 (DE-576)261677926 1872-7980 nnns volume:429 year:2018 pages:11-18 extent:8 https://doi.org/10.1016/j.canlet.2018.05.008 Verlag Resolving-System Volltext http://www.sciencedirect.com/science/article/pii/S0304383518303276 Verlag Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 AR 429 2018 11-18 8 2013 01 DE-16-250 3417702046 00 --%%-- --%%-- --%%-- --%%-- l01 02-04-19 2013 01 DE-16-250 00 s hd2018 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_6 2013 01 DE-16-250 03 s s_8 2013 01 DE-16-250 04 p (DE-627)1439807345 Abba, Mohammed L. 2013 01 DE-16-250 04 k (DE-627)1416468528 III. Medizinische Klinik 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_1 2013 01 DE-16-250 05 p (DE-627)1524969370 Patil, Nitin 2013 01 DE-16-250 05 k (DE-627)1416469214 Zentrum für Biomedizin und Medizintechnik Mannheim (CBTM) 2013 01 DE-16-250 05 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 05 s pos_2 2013 01 DE-16-250 06 p (DE-627)1451500963 Leupold, Jörg 2013 01 DE-16-250 06 k (DE-627)1416469214 Zentrum für Biomedizin und Medizintechnik Mannheim (CBTM) 2013 01 DE-16-250 06 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 06 s pos_3 2013 01 DE-16-250 07 p (DE-627)1439807183 Allgayer, Heike 2013 01 DE-16-250 07 k (DE-627)1416469214 Zentrum für Biomedizin und Medizintechnik Mannheim (CBTM) 2013 01 DE-16-250 07 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 07 s pos_6
allfieldsGer	10.1016/j.canlet.2018.05.008 doi (DE-627)166270271X (DE-599)KXP166270271X (OCoLC)1341205881 DE-627 ger DE-627 rda eng Abba, Mohammed L. 1974- verfasserin (DE-588)1024986101 (DE-627)720854369 (DE-576)369801407 aut Prevention of carcinogenesis and metastasis by artemisinin-type drugs Mohammed L. Abba, Nitin Patil, Jörg Hendrik Leupold, Mohamed E.M. Saeed, Thomas Efferth, Heike Allgayer 8 May 2018 8 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Gesehen am 02.04.2019 Artemisia annua (sweet wormwood, qinhao) is an ancient Chinese herbal remedy for pyrexia. Nowadays, artemisinin (qinghaosu) and its derivatives belong to the standard therapies against malaria worldwide, and its discovery has led to the Nobel Prize in Physiology and Medicine to Youyou Tu in 2015. While most attention has been paid to the treatment of malaria, there is increasing evidence that Artemisinin-type drugs bear a considerable potential to treat and prevent cancer. Rather than reporting on therapy of cancer, this review gives a comprehensive and timely overview on the chemopreventive effects of artemisinin and its derivatives against carcinogenesis and metastasis formation, following the multistage model of carcinogenesis (initiation, promotion, progression). The favorable toxicity profile known from malaria studies indicates that artemisinin-type drugs may be safely applied to prevent carcinogenesis and cancer metastasis in human beings. Cancer Carcinogenesis Initation L. Metastasis Prevention Progression Patil, Nitin 1976- verfasserin (DE-588)1031802177 (DE-627)747795371 (DE-576)379534622 aut Leupold, Jörg 1969- verfasserin (DE-588)130056030 (DE-627)488795796 (DE-576)29797310X aut Allgayer, Heike 1969- verfasserin (DE-588)1024987884 (DE-627)720854466 (DE-576)369805003 aut Enthalten in Cancer letters Amsterdam [u.a.] : Elsevier Science, 1975 429(2018), Seite 11-18 Online-Ressource (DE-627)320434796 (DE-600)2004212-7 (DE-576)261677926 1872-7980 nnns volume:429 year:2018 pages:11-18 extent:8 https://doi.org/10.1016/j.canlet.2018.05.008 Verlag Resolving-System Volltext http://www.sciencedirect.com/science/article/pii/S0304383518303276 Verlag Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 AR 429 2018 11-18 8 2013 01 DE-16-250 3417702046 00 --%%-- --%%-- --%%-- --%%-- l01 02-04-19 2013 01 DE-16-250 00 s hd2018 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_6 2013 01 DE-16-250 03 s s_8 2013 01 DE-16-250 04 p (DE-627)1439807345 Abba, Mohammed L. 2013 01 DE-16-250 04 k (DE-627)1416468528 III. Medizinische Klinik 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_1 2013 01 DE-16-250 05 p (DE-627)1524969370 Patil, Nitin 2013 01 DE-16-250 05 k (DE-627)1416469214 Zentrum für Biomedizin und Medizintechnik Mannheim (CBTM) 2013 01 DE-16-250 05 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 05 s pos_2 2013 01 DE-16-250 06 p (DE-627)1451500963 Leupold, Jörg 2013 01 DE-16-250 06 k (DE-627)1416469214 Zentrum für Biomedizin und Medizintechnik Mannheim (CBTM) 2013 01 DE-16-250 06 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 06 s pos_3 2013 01 DE-16-250 07 p (DE-627)1439807183 Allgayer, Heike 2013 01 DE-16-250 07 k (DE-627)1416469214 Zentrum für Biomedizin und Medizintechnik Mannheim (CBTM) 2013 01 DE-16-250 07 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 07 s pos_6
allfieldsSound	10.1016/j.canlet.2018.05.008 doi (DE-627)166270271X (DE-599)KXP166270271X (OCoLC)1341205881 DE-627 ger DE-627 rda eng Abba, Mohammed L. 1974- verfasserin (DE-588)1024986101 (DE-627)720854369 (DE-576)369801407 aut Prevention of carcinogenesis and metastasis by artemisinin-type drugs Mohammed L. Abba, Nitin Patil, Jörg Hendrik Leupold, Mohamed E.M. Saeed, Thomas Efferth, Heike Allgayer 8 May 2018 8 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Gesehen am 02.04.2019 Artemisia annua (sweet wormwood, qinhao) is an ancient Chinese herbal remedy for pyrexia. Nowadays, artemisinin (qinghaosu) and its derivatives belong to the standard therapies against malaria worldwide, and its discovery has led to the Nobel Prize in Physiology and Medicine to Youyou Tu in 2015. While most attention has been paid to the treatment of malaria, there is increasing evidence that Artemisinin-type drugs bear a considerable potential to treat and prevent cancer. Rather than reporting on therapy of cancer, this review gives a comprehensive and timely overview on the chemopreventive effects of artemisinin and its derivatives against carcinogenesis and metastasis formation, following the multistage model of carcinogenesis (initiation, promotion, progression). The favorable toxicity profile known from malaria studies indicates that artemisinin-type drugs may be safely applied to prevent carcinogenesis and cancer metastasis in human beings. Cancer Carcinogenesis Initation L. Metastasis Prevention Progression Patil, Nitin 1976- verfasserin (DE-588)1031802177 (DE-627)747795371 (DE-576)379534622 aut Leupold, Jörg 1969- verfasserin (DE-588)130056030 (DE-627)488795796 (DE-576)29797310X aut Allgayer, Heike 1969- verfasserin (DE-588)1024987884 (DE-627)720854466 (DE-576)369805003 aut Enthalten in Cancer letters Amsterdam [u.a.] : Elsevier Science, 1975 429(2018), Seite 11-18 Online-Ressource (DE-627)320434796 (DE-600)2004212-7 (DE-576)261677926 1872-7980 nnns volume:429 year:2018 pages:11-18 extent:8 https://doi.org/10.1016/j.canlet.2018.05.008 Verlag Resolving-System Volltext http://www.sciencedirect.com/science/article/pii/S0304383518303276 Verlag Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 AR 429 2018 11-18 8 2013 01 DE-16-250 3417702046 00 --%%-- --%%-- --%%-- --%%-- l01 02-04-19 2013 01 DE-16-250 00 s hd2018 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_6 2013 01 DE-16-250 03 s s_8 2013 01 DE-16-250 04 p (DE-627)1439807345 Abba, Mohammed L. 2013 01 DE-16-250 04 k (DE-627)1416468528 III. Medizinische Klinik 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_1 2013 01 DE-16-250 05 p (DE-627)1524969370 Patil, Nitin 2013 01 DE-16-250 05 k (DE-627)1416469214 Zentrum für Biomedizin und Medizintechnik Mannheim (CBTM) 2013 01 DE-16-250 05 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 05 s pos_2 2013 01 DE-16-250 06 p (DE-627)1451500963 Leupold, Jörg 2013 01 DE-16-250 06 k (DE-627)1416469214 Zentrum für Biomedizin und Medizintechnik Mannheim (CBTM) 2013 01 DE-16-250 06 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 06 s pos_3 2013 01 DE-16-250 07 p (DE-627)1439807183 Allgayer, Heike 2013 01 DE-16-250 07 k (DE-627)1416469214 Zentrum für Biomedizin und Medizintechnik Mannheim (CBTM) 2013 01 DE-16-250 07 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 07 s pos_6
language	English
source	Enthalten in Cancer letters 429(2018), Seite 11-18 volume:429 year:2018 pages:11-18 extent:8
sourceStr	Enthalten in Cancer letters 429(2018), Seite 11-18 volume:429 year:2018 pages:11-18 extent:8
format_phy_str_mv	Article
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institution	findex.gbv.de
selectbib_iln_str_mv	2013@01
topic_facet	Cancer Carcinogenesis Initation L. Metastasis Prevention Progression
sw_local_iln_str_mv	2013:hd2018 DE-16-250:hd2018 2013:wissenschaftlicher Artikel (Zeitschrift) DE-16-250:wissenschaftlicher Artikel (Zeitschrift) 2013:per_6 DE-16-250:per_6 2013:s_8 DE-16-250:s_8 2013:Abba, Mohammed L. DE-16-250:Abba, Mohammed L. 2013:III. Medizinische Klinik DE-16-250:III. Medizinische Klinik 2013:Verfasser DE-16-250:Verfasser 2013:pos_1 DE-16-250:pos_1 2013:Patil, Nitin DE-16-250:Patil, Nitin 2013:Zentrum für Biomedizin und Medizintechnik Mannheim (CBTM) DE-16-250:Zentrum für Biomedizin und Medizintechnik Mannheim (CBTM) 2013:pos_2 DE-16-250:pos_2 2013:Leupold, Jörg DE-16-250:Leupold, Jörg 2013:pos_3 DE-16-250:pos_3 2013:Allgayer, Heike DE-16-250:Allgayer, Heike 2013:pos_6 DE-16-250:pos_6
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container_title	Cancer letters
authorswithroles_txt_mv	Abba, Mohammed L. @@aut@@ Patil, Nitin @@aut@@ Leupold, Jörg @@aut@@ Allgayer, Heike @@aut@@
publishDateDaySort_date	2018-01-01T00:00:00Z
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topic	misc Cancer misc Carcinogenesis misc Initation misc L. misc Metastasis misc Prevention misc Progression 2013 hd2018 2013 wissenschaftlicher Artikel (Zeitschrift) 2013 per_6 2013 s_8 2013 Abba, Mohammed L. 2013 III. Medizinische Klinik 2013 Verfasser 2013 pos_1 2013 Patil, Nitin 2013 Zentrum für Biomedizin und Medizintechnik Mannheim (CBTM) 2013 pos_2 2013 Leupold, Jörg 2013 pos_3 2013 Allgayer, Heike 2013 pos_6
topic_unstemmed	misc Cancer misc Carcinogenesis misc Initation misc L. misc Metastasis misc Prevention misc Progression 2013 hd2018 2013 wissenschaftlicher Artikel (Zeitschrift) 2013 per_6 2013 s_8 2013 Abba, Mohammed L. 2013 III. Medizinische Klinik 2013 Verfasser 2013 pos_1 2013 Patil, Nitin 2013 Zentrum für Biomedizin und Medizintechnik Mannheim (CBTM) 2013 pos_2 2013 Leupold, Jörg 2013 pos_3 2013 Allgayer, Heike 2013 pos_6
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title	Prevention of carcinogenesis and metastasis by artemisinin-type drugs
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title_full	Prevention of carcinogenesis and metastasis by artemisinin-type drugs Mohammed L. Abba, Nitin Patil, Jörg Hendrik Leupold, Mohamed E.M. Saeed, Thomas Efferth, Heike Allgayer
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title_sort	prevention of carcinogenesis and metastasis by artemisinin-type drugs
title_auth	Prevention of carcinogenesis and metastasis by artemisinin-type drugs
abstract	Artemisia annua (sweet wormwood, qinhao) is an ancient Chinese herbal remedy for pyrexia. Nowadays, artemisinin (qinghaosu) and its derivatives belong to the standard therapies against malaria worldwide, and its discovery has led to the Nobel Prize in Physiology and Medicine to Youyou Tu in 2015. While most attention has been paid to the treatment of malaria, there is increasing evidence that Artemisinin-type drugs bear a considerable potential to treat and prevent cancer. Rather than reporting on therapy of cancer, this review gives a comprehensive and timely overview on the chemopreventive effects of artemisinin and its derivatives against carcinogenesis and metastasis formation, following the multistage model of carcinogenesis (initiation, promotion, progression). The favorable toxicity profile known from malaria studies indicates that artemisinin-type drugs may be safely applied to prevent carcinogenesis and cancer metastasis in human beings. Gesehen am 02.04.2019
abstractGer	Artemisia annua (sweet wormwood, qinhao) is an ancient Chinese herbal remedy for pyrexia. Nowadays, artemisinin (qinghaosu) and its derivatives belong to the standard therapies against malaria worldwide, and its discovery has led to the Nobel Prize in Physiology and Medicine to Youyou Tu in 2015. While most attention has been paid to the treatment of malaria, there is increasing evidence that Artemisinin-type drugs bear a considerable potential to treat and prevent cancer. Rather than reporting on therapy of cancer, this review gives a comprehensive and timely overview on the chemopreventive effects of artemisinin and its derivatives against carcinogenesis and metastasis formation, following the multistage model of carcinogenesis (initiation, promotion, progression). The favorable toxicity profile known from malaria studies indicates that artemisinin-type drugs may be safely applied to prevent carcinogenesis and cancer metastasis in human beings. Gesehen am 02.04.2019
abstract_unstemmed	Artemisia annua (sweet wormwood, qinhao) is an ancient Chinese herbal remedy for pyrexia. Nowadays, artemisinin (qinghaosu) and its derivatives belong to the standard therapies against malaria worldwide, and its discovery has led to the Nobel Prize in Physiology and Medicine to Youyou Tu in 2015. While most attention has been paid to the treatment of malaria, there is increasing evidence that Artemisinin-type drugs bear a considerable potential to treat and prevent cancer. Rather than reporting on therapy of cancer, this review gives a comprehensive and timely overview on the chemopreventive effects of artemisinin and its derivatives against carcinogenesis and metastasis formation, following the multistage model of carcinogenesis (initiation, promotion, progression). The favorable toxicity profile known from malaria studies indicates that artemisinin-type drugs may be safely applied to prevent carcinogenesis and cancer metastasis in human beings. Gesehen am 02.04.2019
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title_short	Prevention of carcinogenesis and metastasis by artemisinin-type drugs
url	https://doi.org/10.1016/j.canlet.2018.05.008 http://www.sciencedirect.com/science/article/pii/S0304383518303276
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