A combined planning approach for improved functional and esthetic outcome of bimaxillary rotation advancement for treatment of obstructive sleep apnea using 3D biomechanical modeling

In recent years, bimaxillary rotation advancement (BRA) has become the method of choice for surgical treatment of obstructive sleep apnea (OSA). As dislocation of the jaw bones affects both, airways and facial contours, surgeons are facing the challenge of finding an optimal jaw position that allows...
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Autor*in:	Frey, Robert-Marie - 1969- [verfasserIn] Gabrielova, Barbora [verfasserIn] Gladilin, Evgeny [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	August 9, 2018

Schlagwörter:	Anisotropy Face Jaw Mandible Maxilla Pharyngeal muscles Soft tissues Surgical and invasive medical procedures

Anmerkung:	Gesehen am 24.07.2019
Umfang:	15

Übergeordnetes Werk:	Enthalten in: PLOS ONE - San Francisco, California, US : PLOS, 2006, 13(2018,8) Artikel-Nummer e0199956, 15 Seiten
Übergeordnetes Werk:	volume:13 ; year:2018 ; number:8 ; extent:15

Links:	Volltext Volltext

DOI / URN:	10.1371/journal.pone.0199956

Katalog-ID:	1669935426

Internformat


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520			\|a In recent years, bimaxillary rotation advancement (BRA) has become the method of choice for surgical treatment of obstructive sleep apnea (OSA). As dislocation of the jaw bones affects both, airways and facial contours, surgeons are facing the challenge of finding an optimal jaw position that allows for the reestablishment of normal airway ventilation and esthetic surgical outcome. Owing to the complexity of the facial anatomy and its mechanical behavior, individual planning of surgical OSA treatment under consideration of functional and esthetic aspects presents a challenge that surgeons typically approach in a non-quantitative manner using subjective evaluation and clinical experience. This paper describes a framework for individual planning of OSA treatment using bimaxillary rotation advancement, which relies on computational modeling of hard and soft tissue mechanics. The described framework for simulation of functional and esthetic post-surgery outcome was used in 10 OSA patients. Comparison of the simulation results with post-surgery data reveals that biomechanical simulation provides a reliable estimate for post-surgery facial tissue behavior and antero-posterior airway extension, but fails to accurately describe a surprisingly large lateral stretch of the velopharyngeal region. This discrepancy is traced back to anisotropic effects of pharyngeal muscles. Possible approaches to improving the accuracy of model predictions and defining sharp criteria for optimizing combined OSA planning are discussed.
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allfields	10.1371/journal.pone.0199956 doi (DE-627)1669935426 (DE-599)KXP1669935426 (OCoLC)1341234748 DE-627 ger DE-627 rda eng Frey, Robert-Marie 1969- verfasserin (DE-588)118018167 (DE-627)079193927 (DE-576)291670482 aut A combined planning approach for improved functional and esthetic outcome of bimaxillary rotation advancement for treatment of obstructive sleep apnea using 3D biomechanical modeling Robert Frey, Barbora Gabrielova, Evgeny Gladilin August 9, 2018 15 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Gesehen am 24.07.2019 In recent years, bimaxillary rotation advancement (BRA) has become the method of choice for surgical treatment of obstructive sleep apnea (OSA). As dislocation of the jaw bones affects both, airways and facial contours, surgeons are facing the challenge of finding an optimal jaw position that allows for the reestablishment of normal airway ventilation and esthetic surgical outcome. Owing to the complexity of the facial anatomy and its mechanical behavior, individual planning of surgical OSA treatment under consideration of functional and esthetic aspects presents a challenge that surgeons typically approach in a non-quantitative manner using subjective evaluation and clinical experience. This paper describes a framework for individual planning of OSA treatment using bimaxillary rotation advancement, which relies on computational modeling of hard and soft tissue mechanics. The described framework for simulation of functional and esthetic post-surgery outcome was used in 10 OSA patients. Comparison of the simulation results with post-surgery data reveals that biomechanical simulation provides a reliable estimate for post-surgery facial tissue behavior and antero-posterior airway extension, but fails to accurately describe a surprisingly large lateral stretch of the velopharyngeal region. This discrepancy is traced back to anisotropic effects of pharyngeal muscles. Possible approaches to improving the accuracy of model predictions and defining sharp criteria for optimizing combined OSA planning are discussed. Anisotropy Face Jaw Mandible Maxilla Pharyngeal muscles Soft tissues Surgical and invasive medical procedures Gabrielova, Barbora verfasserin (DE-588)1191271579 (DE-627)1669937119 aut Gladilin, Evgeny verfasserin (DE-588)1162502290 (DE-627)1026599474 (DE-576)348573685 aut Enthalten in PLOS ONE San Francisco, California, US : PLOS, 2006 13(2018,8) Artikel-Nummer e0199956, 15 Seiten Online-Ressource (DE-627)523574592 (DE-600)2267670-3 (DE-576)281331979 1932-6203 nnns volume:13 year:2018 number:8 extent:15 https://doi.org/10.1371/journal.pone.0199956 Verlag Resolving-System Volltext https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199956 Verlag Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_34 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_235 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2018 8 15 13(2018,8) Artikel-Nummer e0199956, 15 Seiten 2013 01 DE-16-250 3496497319 00 --%%-- --%%-- --%%-- --%%-- l01 24-07-19 2013 01 DE-16-250 00 s hd2018 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_3 2013 01 DE-16-250 03 s s_15 2013 01 DE-16-250 04 p (DE-627)1577436997 Gladilin, Evgeny 2013 01 DE-16-250 04 k (DE-627)1416734031 BIOQUANT 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_3
spelling	10.1371/journal.pone.0199956 doi (DE-627)1669935426 (DE-599)KXP1669935426 (OCoLC)1341234748 DE-627 ger DE-627 rda eng Frey, Robert-Marie 1969- verfasserin (DE-588)118018167 (DE-627)079193927 (DE-576)291670482 aut A combined planning approach for improved functional and esthetic outcome of bimaxillary rotation advancement for treatment of obstructive sleep apnea using 3D biomechanical modeling Robert Frey, Barbora Gabrielova, Evgeny Gladilin August 9, 2018 15 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Gesehen am 24.07.2019 In recent years, bimaxillary rotation advancement (BRA) has become the method of choice for surgical treatment of obstructive sleep apnea (OSA). As dislocation of the jaw bones affects both, airways and facial contours, surgeons are facing the challenge of finding an optimal jaw position that allows for the reestablishment of normal airway ventilation and esthetic surgical outcome. Owing to the complexity of the facial anatomy and its mechanical behavior, individual planning of surgical OSA treatment under consideration of functional and esthetic aspects presents a challenge that surgeons typically approach in a non-quantitative manner using subjective evaluation and clinical experience. This paper describes a framework for individual planning of OSA treatment using bimaxillary rotation advancement, which relies on computational modeling of hard and soft tissue mechanics. The described framework for simulation of functional and esthetic post-surgery outcome was used in 10 OSA patients. Comparison of the simulation results with post-surgery data reveals that biomechanical simulation provides a reliable estimate for post-surgery facial tissue behavior and antero-posterior airway extension, but fails to accurately describe a surprisingly large lateral stretch of the velopharyngeal region. This discrepancy is traced back to anisotropic effects of pharyngeal muscles. Possible approaches to improving the accuracy of model predictions and defining sharp criteria for optimizing combined OSA planning are discussed. Anisotropy Face Jaw Mandible Maxilla Pharyngeal muscles Soft tissues Surgical and invasive medical procedures Gabrielova, Barbora verfasserin (DE-588)1191271579 (DE-627)1669937119 aut Gladilin, Evgeny verfasserin (DE-588)1162502290 (DE-627)1026599474 (DE-576)348573685 aut Enthalten in PLOS ONE San Francisco, California, US : PLOS, 2006 13(2018,8) Artikel-Nummer e0199956, 15 Seiten Online-Ressource (DE-627)523574592 (DE-600)2267670-3 (DE-576)281331979 1932-6203 nnns volume:13 year:2018 number:8 extent:15 https://doi.org/10.1371/journal.pone.0199956 Verlag Resolving-System Volltext https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199956 Verlag Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_34 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_235 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2018 8 15 13(2018,8) Artikel-Nummer e0199956, 15 Seiten 2013 01 DE-16-250 3496497319 00 --%%-- --%%-- --%%-- --%%-- l01 24-07-19 2013 01 DE-16-250 00 s hd2018 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_3 2013 01 DE-16-250 03 s s_15 2013 01 DE-16-250 04 p (DE-627)1577436997 Gladilin, Evgeny 2013 01 DE-16-250 04 k (DE-627)1416734031 BIOQUANT 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_3
allfields_unstemmed	10.1371/journal.pone.0199956 doi (DE-627)1669935426 (DE-599)KXP1669935426 (OCoLC)1341234748 DE-627 ger DE-627 rda eng Frey, Robert-Marie 1969- verfasserin (DE-588)118018167 (DE-627)079193927 (DE-576)291670482 aut A combined planning approach for improved functional and esthetic outcome of bimaxillary rotation advancement for treatment of obstructive sleep apnea using 3D biomechanical modeling Robert Frey, Barbora Gabrielova, Evgeny Gladilin August 9, 2018 15 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Gesehen am 24.07.2019 In recent years, bimaxillary rotation advancement (BRA) has become the method of choice for surgical treatment of obstructive sleep apnea (OSA). As dislocation of the jaw bones affects both, airways and facial contours, surgeons are facing the challenge of finding an optimal jaw position that allows for the reestablishment of normal airway ventilation and esthetic surgical outcome. Owing to the complexity of the facial anatomy and its mechanical behavior, individual planning of surgical OSA treatment under consideration of functional and esthetic aspects presents a challenge that surgeons typically approach in a non-quantitative manner using subjective evaluation and clinical experience. This paper describes a framework for individual planning of OSA treatment using bimaxillary rotation advancement, which relies on computational modeling of hard and soft tissue mechanics. The described framework for simulation of functional and esthetic post-surgery outcome was used in 10 OSA patients. Comparison of the simulation results with post-surgery data reveals that biomechanical simulation provides a reliable estimate for post-surgery facial tissue behavior and antero-posterior airway extension, but fails to accurately describe a surprisingly large lateral stretch of the velopharyngeal region. This discrepancy is traced back to anisotropic effects of pharyngeal muscles. Possible approaches to improving the accuracy of model predictions and defining sharp criteria for optimizing combined OSA planning are discussed. Anisotropy Face Jaw Mandible Maxilla Pharyngeal muscles Soft tissues Surgical and invasive medical procedures Gabrielova, Barbora verfasserin (DE-588)1191271579 (DE-627)1669937119 aut Gladilin, Evgeny verfasserin (DE-588)1162502290 (DE-627)1026599474 (DE-576)348573685 aut Enthalten in PLOS ONE San Francisco, California, US : PLOS, 2006 13(2018,8) Artikel-Nummer e0199956, 15 Seiten Online-Ressource (DE-627)523574592 (DE-600)2267670-3 (DE-576)281331979 1932-6203 nnns volume:13 year:2018 number:8 extent:15 https://doi.org/10.1371/journal.pone.0199956 Verlag Resolving-System Volltext https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199956 Verlag Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_34 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_235 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2018 8 15 13(2018,8) Artikel-Nummer e0199956, 15 Seiten 2013 01 DE-16-250 3496497319 00 --%%-- --%%-- --%%-- --%%-- l01 24-07-19 2013 01 DE-16-250 00 s hd2018 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_3 2013 01 DE-16-250 03 s s_15 2013 01 DE-16-250 04 p (DE-627)1577436997 Gladilin, Evgeny 2013 01 DE-16-250 04 k (DE-627)1416734031 BIOQUANT 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_3
allfieldsGer	10.1371/journal.pone.0199956 doi (DE-627)1669935426 (DE-599)KXP1669935426 (OCoLC)1341234748 DE-627 ger DE-627 rda eng Frey, Robert-Marie 1969- verfasserin (DE-588)118018167 (DE-627)079193927 (DE-576)291670482 aut A combined planning approach for improved functional and esthetic outcome of bimaxillary rotation advancement for treatment of obstructive sleep apnea using 3D biomechanical modeling Robert Frey, Barbora Gabrielova, Evgeny Gladilin August 9, 2018 15 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Gesehen am 24.07.2019 In recent years, bimaxillary rotation advancement (BRA) has become the method of choice for surgical treatment of obstructive sleep apnea (OSA). As dislocation of the jaw bones affects both, airways and facial contours, surgeons are facing the challenge of finding an optimal jaw position that allows for the reestablishment of normal airway ventilation and esthetic surgical outcome. Owing to the complexity of the facial anatomy and its mechanical behavior, individual planning of surgical OSA treatment under consideration of functional and esthetic aspects presents a challenge that surgeons typically approach in a non-quantitative manner using subjective evaluation and clinical experience. This paper describes a framework for individual planning of OSA treatment using bimaxillary rotation advancement, which relies on computational modeling of hard and soft tissue mechanics. The described framework for simulation of functional and esthetic post-surgery outcome was used in 10 OSA patients. Comparison of the simulation results with post-surgery data reveals that biomechanical simulation provides a reliable estimate for post-surgery facial tissue behavior and antero-posterior airway extension, but fails to accurately describe a surprisingly large lateral stretch of the velopharyngeal region. This discrepancy is traced back to anisotropic effects of pharyngeal muscles. Possible approaches to improving the accuracy of model predictions and defining sharp criteria for optimizing combined OSA planning are discussed. Anisotropy Face Jaw Mandible Maxilla Pharyngeal muscles Soft tissues Surgical and invasive medical procedures Gabrielova, Barbora verfasserin (DE-588)1191271579 (DE-627)1669937119 aut Gladilin, Evgeny verfasserin (DE-588)1162502290 (DE-627)1026599474 (DE-576)348573685 aut Enthalten in PLOS ONE San Francisco, California, US : PLOS, 2006 13(2018,8) Artikel-Nummer e0199956, 15 Seiten Online-Ressource (DE-627)523574592 (DE-600)2267670-3 (DE-576)281331979 1932-6203 nnns volume:13 year:2018 number:8 extent:15 https://doi.org/10.1371/journal.pone.0199956 Verlag Resolving-System Volltext https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199956 Verlag Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_34 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_235 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2018 8 15 13(2018,8) Artikel-Nummer e0199956, 15 Seiten 2013 01 DE-16-250 3496497319 00 --%%-- --%%-- --%%-- --%%-- l01 24-07-19 2013 01 DE-16-250 00 s hd2018 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_3 2013 01 DE-16-250 03 s s_15 2013 01 DE-16-250 04 p (DE-627)1577436997 Gladilin, Evgeny 2013 01 DE-16-250 04 k (DE-627)1416734031 BIOQUANT 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_3
allfieldsSound	10.1371/journal.pone.0199956 doi (DE-627)1669935426 (DE-599)KXP1669935426 (OCoLC)1341234748 DE-627 ger DE-627 rda eng Frey, Robert-Marie 1969- verfasserin (DE-588)118018167 (DE-627)079193927 (DE-576)291670482 aut A combined planning approach for improved functional and esthetic outcome of bimaxillary rotation advancement for treatment of obstructive sleep apnea using 3D biomechanical modeling Robert Frey, Barbora Gabrielova, Evgeny Gladilin August 9, 2018 15 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Gesehen am 24.07.2019 In recent years, bimaxillary rotation advancement (BRA) has become the method of choice for surgical treatment of obstructive sleep apnea (OSA). As dislocation of the jaw bones affects both, airways and facial contours, surgeons are facing the challenge of finding an optimal jaw position that allows for the reestablishment of normal airway ventilation and esthetic surgical outcome. Owing to the complexity of the facial anatomy and its mechanical behavior, individual planning of surgical OSA treatment under consideration of functional and esthetic aspects presents a challenge that surgeons typically approach in a non-quantitative manner using subjective evaluation and clinical experience. This paper describes a framework for individual planning of OSA treatment using bimaxillary rotation advancement, which relies on computational modeling of hard and soft tissue mechanics. The described framework for simulation of functional and esthetic post-surgery outcome was used in 10 OSA patients. Comparison of the simulation results with post-surgery data reveals that biomechanical simulation provides a reliable estimate for post-surgery facial tissue behavior and antero-posterior airway extension, but fails to accurately describe a surprisingly large lateral stretch of the velopharyngeal region. This discrepancy is traced back to anisotropic effects of pharyngeal muscles. Possible approaches to improving the accuracy of model predictions and defining sharp criteria for optimizing combined OSA planning are discussed. Anisotropy Face Jaw Mandible Maxilla Pharyngeal muscles Soft tissues Surgical and invasive medical procedures Gabrielova, Barbora verfasserin (DE-588)1191271579 (DE-627)1669937119 aut Gladilin, Evgeny verfasserin (DE-588)1162502290 (DE-627)1026599474 (DE-576)348573685 aut Enthalten in PLOS ONE San Francisco, California, US : PLOS, 2006 13(2018,8) Artikel-Nummer e0199956, 15 Seiten Online-Ressource (DE-627)523574592 (DE-600)2267670-3 (DE-576)281331979 1932-6203 nnns volume:13 year:2018 number:8 extent:15 https://doi.org/10.1371/journal.pone.0199956 Verlag Resolving-System Volltext https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199956 Verlag Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_34 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_235 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2018 8 15 13(2018,8) Artikel-Nummer e0199956, 15 Seiten 2013 01 DE-16-250 3496497319 00 --%%-- --%%-- --%%-- --%%-- l01 24-07-19 2013 01 DE-16-250 00 s hd2018 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_3 2013 01 DE-16-250 03 s s_15 2013 01 DE-16-250 04 p (DE-627)1577436997 Gladilin, Evgeny 2013 01 DE-16-250 04 k (DE-627)1416734031 BIOQUANT 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_3
language	English
source	Enthalten in PLOS ONE 13(2018,8) Artikel-Nummer e0199956, 15 Seiten volume:13 year:2018 number:8 extent:15
sourceStr	Enthalten in PLOS ONE 13(2018,8) Artikel-Nummer e0199956, 15 Seiten volume:13 year:2018 number:8 extent:15
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topic_facet	Anisotropy Face Jaw Mandible Maxilla Pharyngeal muscles Soft tissues Surgical and invasive medical procedures
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authorswithroles_txt_mv	Frey, Robert-Marie @@aut@@ Gabrielova, Barbora @@aut@@ Gladilin, Evgeny @@aut@@
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topic	misc Anisotropy misc Face misc Jaw misc Mandible misc Maxilla misc Pharyngeal muscles misc Soft tissues misc Surgical and invasive medical procedures 2013 hd2018 2013 wissenschaftlicher Artikel (Zeitschrift) 2013 per_3 2013 s_15 2013 Gladilin, Evgeny 2013 BIOQUANT 2013 Verfasser 2013 pos_3
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title	A combined planning approach for improved functional and esthetic outcome of bimaxillary rotation advancement for treatment of obstructive sleep apnea using 3D biomechanical modeling
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title_full	A combined planning approach for improved functional and esthetic outcome of bimaxillary rotation advancement for treatment of obstructive sleep apnea using 3D biomechanical modeling Robert Frey, Barbora Gabrielova, Evgeny Gladilin
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title_sort	combined planning approach for improved functional and esthetic outcome of bimaxillary rotation advancement for treatment of obstructive sleep apnea using 3d biomechanical modeling
title_auth	A combined planning approach for improved functional and esthetic outcome of bimaxillary rotation advancement for treatment of obstructive sleep apnea using 3D biomechanical modeling
abstract	In recent years, bimaxillary rotation advancement (BRA) has become the method of choice for surgical treatment of obstructive sleep apnea (OSA). As dislocation of the jaw bones affects both, airways and facial contours, surgeons are facing the challenge of finding an optimal jaw position that allows for the reestablishment of normal airway ventilation and esthetic surgical outcome. Owing to the complexity of the facial anatomy and its mechanical behavior, individual planning of surgical OSA treatment under consideration of functional and esthetic aspects presents a challenge that surgeons typically approach in a non-quantitative manner using subjective evaluation and clinical experience. This paper describes a framework for individual planning of OSA treatment using bimaxillary rotation advancement, which relies on computational modeling of hard and soft tissue mechanics. The described framework for simulation of functional and esthetic post-surgery outcome was used in 10 OSA patients. Comparison of the simulation results with post-surgery data reveals that biomechanical simulation provides a reliable estimate for post-surgery facial tissue behavior and antero-posterior airway extension, but fails to accurately describe a surprisingly large lateral stretch of the velopharyngeal region. This discrepancy is traced back to anisotropic effects of pharyngeal muscles. Possible approaches to improving the accuracy of model predictions and defining sharp criteria for optimizing combined OSA planning are discussed. Gesehen am 24.07.2019
abstractGer	In recent years, bimaxillary rotation advancement (BRA) has become the method of choice for surgical treatment of obstructive sleep apnea (OSA). As dislocation of the jaw bones affects both, airways and facial contours, surgeons are facing the challenge of finding an optimal jaw position that allows for the reestablishment of normal airway ventilation and esthetic surgical outcome. Owing to the complexity of the facial anatomy and its mechanical behavior, individual planning of surgical OSA treatment under consideration of functional and esthetic aspects presents a challenge that surgeons typically approach in a non-quantitative manner using subjective evaluation and clinical experience. This paper describes a framework for individual planning of OSA treatment using bimaxillary rotation advancement, which relies on computational modeling of hard and soft tissue mechanics. The described framework for simulation of functional and esthetic post-surgery outcome was used in 10 OSA patients. Comparison of the simulation results with post-surgery data reveals that biomechanical simulation provides a reliable estimate for post-surgery facial tissue behavior and antero-posterior airway extension, but fails to accurately describe a surprisingly large lateral stretch of the velopharyngeal region. This discrepancy is traced back to anisotropic effects of pharyngeal muscles. Possible approaches to improving the accuracy of model predictions and defining sharp criteria for optimizing combined OSA planning are discussed. Gesehen am 24.07.2019
abstract_unstemmed	In recent years, bimaxillary rotation advancement (BRA) has become the method of choice for surgical treatment of obstructive sleep apnea (OSA). As dislocation of the jaw bones affects both, airways and facial contours, surgeons are facing the challenge of finding an optimal jaw position that allows for the reestablishment of normal airway ventilation and esthetic surgical outcome. Owing to the complexity of the facial anatomy and its mechanical behavior, individual planning of surgical OSA treatment under consideration of functional and esthetic aspects presents a challenge that surgeons typically approach in a non-quantitative manner using subjective evaluation and clinical experience. This paper describes a framework for individual planning of OSA treatment using bimaxillary rotation advancement, which relies on computational modeling of hard and soft tissue mechanics. The described framework for simulation of functional and esthetic post-surgery outcome was used in 10 OSA patients. Comparison of the simulation results with post-surgery data reveals that biomechanical simulation provides a reliable estimate for post-surgery facial tissue behavior and antero-posterior airway extension, but fails to accurately describe a surprisingly large lateral stretch of the velopharyngeal region. This discrepancy is traced back to anisotropic effects of pharyngeal muscles. Possible approaches to improving the accuracy of model predictions and defining sharp criteria for optimizing combined OSA planning are discussed. Gesehen am 24.07.2019
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title_short	A combined planning approach for improved functional and esthetic outcome of bimaxillary rotation advancement for treatment of obstructive sleep apnea using 3D biomechanical modeling
url	https://doi.org/10.1371/journal.pone.0199956 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199956
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author2	Gabrielova, Barbora Gladilin, Evgeny
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doi_str	10.1371/journal.pone.0199956
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up_date	2024-07-05T01:42:46.629Z
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As dislocation of the jaw bones affects both, airways and facial contours, surgeons are facing the challenge of finding an optimal jaw position that allows for the reestablishment of normal airway ventilation and esthetic surgical outcome. Owing to the complexity of the facial anatomy and its mechanical behavior, individual planning of surgical OSA treatment under consideration of functional and esthetic aspects presents a challenge that surgeons typically approach in a non-quantitative manner using subjective evaluation and clinical experience. This paper describes a framework for individual planning of OSA treatment using bimaxillary rotation advancement, which relies on computational modeling of hard and soft tissue mechanics. The described framework for simulation of functional and esthetic post-surgery outcome was used in 10 OSA patients. Comparison of the simulation results with post-surgery data reveals that biomechanical simulation provides a reliable estimate for post-surgery facial tissue behavior and antero-posterior airway extension, but fails to accurately describe a surprisingly large lateral stretch of the velopharyngeal region. This discrepancy is traced back to anisotropic effects of pharyngeal muscles. 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A combined planning approach for improved functional and esthetic outcome of bimaxillary rotation advancement for treatment of obstructive sleep apnea using 3D biomechanical modeling

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