Monitoring contact sensitization to p-phenylenediamine (PPD) by patch testing with PPD 0.3 % in petrolatum
Background Being a contact allergen of general relevance, p-phenylenediamine (PPD) is patch tested in the baseline series. However, PPD 1% in petrolatum may actively sensitize. Patch testing with PPD at 0.35% pet. proved to be safe, as far as active sensitization is concerned. Objectives To determin...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Geier, Johannes [verfasserIn] Ballmer-Weber, Barbara K. [verfasserIn] Dickel, Heinrich - 1967- [verfasserIn] Frosch, Peter J. - 1946- [verfasserIn] Bircher, Andreas - 1953- [verfasserIn] Weisshaar, Elke [verfasserIn] Hillen, Uwe [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
19 June 2013 |
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| Schlagwörter: |
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| Anmerkung: |
Gesehen am 03.02.2020 |
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| Umfang: |
6 |
| Übergeordnetes Werk: |
Enthalten in: Contact dermatitis - Oxford [u.a.] : Wiley-Blackwell, 1975, 69(2013), Seite 26-31 |
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| Übergeordnetes Werk: |
volume:69 ; year:2013 ; pages:26-31 ; extent:6 |
| Links: |
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| DOI / URN: |
10.1111/cod.12075 |
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| Katalog-ID: |
1747185582 |
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| 245 | 1 | 0 | |a Monitoring contact sensitization to p-phenylenediamine (PPD) by patch testing with PPD 0.3 % in petrolatum |c Johannes Geier, Barbara K. Ballmer‐Weber, Heinrich Dickel, Peter J. Frosch, Andreas Bircher, Elke Weisshaar and Uwe Hillen |
| 264 | 1 | |c 19 June 2013 | |
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| 520 | |a Background Being a contact allergen of general relevance, p-phenylenediamine (PPD) is patch tested in the baseline series. However, PPD 1% in petrolatum may actively sensitize. Patch testing with PPD at 0.35% pet. proved to be safe, as far as active sensitization is concerned. Objectives To determine whether PPD 0.3% pet. reliably detects PPD sensitization. Methods Patch testing with PPD 0.3% pet. and 1% pet. synchronously was performed in consecutive patients in a multicentre study within the Information Network of Departments of Dermatology. Results Altogether, 2042 patients were patch tested. PPD 1% pet. yielded 6.0% positive reactions (n = 123), and PPD 0.3% pet. yielded 4.7% (n = 95). The synchronous reproducibility of PPD reactions was similar as known from parallel patch tests with identical PPD concentrations. The diagnostic properties of PPD 0.3% pet. expressed as reaction index and positivity ratio were good. Of the 123 patients reacting to PPD 1% pet., 32 (26%) had no positive reaction to PPD 0.3% pet. In 22 of these 32 patients (69%), no clinical relevance could be found. Conclusions As patch testing with PPD 0.3% pet. is reliable according to our results, we recommend replacing PPD 1% pet. in the baseline series with PPD 0.3% pet. | ||
| 650 | 4 | |a active sensitization | |
| 650 | 4 | |a CAS 106-50-3 | |
| 650 | 4 | |a monitoring of contact allergy | |
| 650 | 4 | |a p-phenylenediamine | |
| 650 | 4 | |a patch test concentration | |
| 650 | 4 | |a patch testing | |
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10.1111/cod.12075 doi (DE-627)1747185582 (DE-599)KXP1747185582 (OCoLC)1341390284 DE-627 ger DE-627 rda eng Geier, Johannes verfasserin (DE-588)1118656563 (DE-627)872168395 (DE-576)479581622 aut Monitoring contact sensitization to p-phenylenediamine (PPD) by patch testing with PPD 0.3 % in petrolatum Johannes Geier, Barbara K. Ballmer‐Weber, Heinrich Dickel, Peter J. Frosch, Andreas Bircher, Elke Weisshaar and Uwe Hillen 19 June 2013 6 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Gesehen am 03.02.2020 Background Being a contact allergen of general relevance, p-phenylenediamine (PPD) is patch tested in the baseline series. However, PPD 1% in petrolatum may actively sensitize. Patch testing with PPD at 0.35% pet. proved to be safe, as far as active sensitization is concerned. Objectives To determine whether PPD 0.3% pet. reliably detects PPD sensitization. Methods Patch testing with PPD 0.3% pet. and 1% pet. synchronously was performed in consecutive patients in a multicentre study within the Information Network of Departments of Dermatology. Results Altogether, 2042 patients were patch tested. PPD 1% pet. yielded 6.0% positive reactions (n = 123), and PPD 0.3% pet. yielded 4.7% (n = 95). The synchronous reproducibility of PPD reactions was similar as known from parallel patch tests with identical PPD concentrations. The diagnostic properties of PPD 0.3% pet. expressed as reaction index and positivity ratio were good. Of the 123 patients reacting to PPD 1% pet., 32 (26%) had no positive reaction to PPD 0.3% pet. In 22 of these 32 patients (69%), no clinical relevance could be found. Conclusions As patch testing with PPD 0.3% pet. is reliable according to our results, we recommend replacing PPD 1% pet. in the baseline series with PPD 0.3% pet. active sensitization CAS 106-50-3 monitoring of contact allergy p-phenylenediamine patch test concentration patch testing Ballmer-Weber, Barbara K. verfasserin (DE-588)124756646 (DE-627)365723495 (DE-576)294484930 aut Dickel, Heinrich 1967- verfasserin (DE-588)142232963 (DE-627)704176289 (DE-576)329633902 aut Frosch, Peter J. 1946- verfasserin (DE-588)11547076X (DE-627)077272412 (DE-576)289901669 aut Bircher, Andreas 1953- verfasserin (DE-588)1173755977 (DE-627)1043604685 (DE-576)515683760 aut Weisshaar, Elke verfasserin (DE-588)1032807369 (DE-627)739344870 (DE-576)271388579 aut Hillen, Uwe verfasserin (DE-588)1171177216 (DE-627)1040422977 (DE-576)513635297 aut Enthalten in Contact dermatitis Oxford [u.a.] : Wiley-Blackwell, 1975 69(2013), Seite 26-31 Online-Ressource (DE-627)32448464X (DE-600)2027120-7 (DE-576)093888872 1600-0536 nnns volume:69 year:2013 pages:26-31 extent:6 https://doi.org/https://doi.org/10.1111/cod.12075 Verlag Resolving-System lizenzpflichtig Volltext https://www.onlinelibrary.wiley.com/doi/abs/10.1111/cod.12075 Verlag lizenzpflichtig Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_266 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 69 2013 26-31 6 2013 01 DE-16-250 3848293927 00 --%%-- --%%-- --%%-- --%%-- l01 03-02-21 2013 01 DE-16-250 00 s hd2013 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_7 2013 01 DE-16-250 03 s s_6 2013 01 DE-16-250 04 p (DE-627)1450298214 Weisshaar, Elke 2013 01 DE-16-250 04 k (DE-627)1416741372 Universitäts-Hautklinik 2013 01 DE-16-250 04 k (DE-627)1416466967 Medizinische Fakultät Heidelberg 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_6 |
| spelling |
10.1111/cod.12075 doi (DE-627)1747185582 (DE-599)KXP1747185582 (OCoLC)1341390284 DE-627 ger DE-627 rda eng Geier, Johannes verfasserin (DE-588)1118656563 (DE-627)872168395 (DE-576)479581622 aut Monitoring contact sensitization to p-phenylenediamine (PPD) by patch testing with PPD 0.3 % in petrolatum Johannes Geier, Barbara K. Ballmer‐Weber, Heinrich Dickel, Peter J. Frosch, Andreas Bircher, Elke Weisshaar and Uwe Hillen 19 June 2013 6 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Gesehen am 03.02.2020 Background Being a contact allergen of general relevance, p-phenylenediamine (PPD) is patch tested in the baseline series. However, PPD 1% in petrolatum may actively sensitize. Patch testing with PPD at 0.35% pet. proved to be safe, as far as active sensitization is concerned. Objectives To determine whether PPD 0.3% pet. reliably detects PPD sensitization. Methods Patch testing with PPD 0.3% pet. and 1% pet. synchronously was performed in consecutive patients in a multicentre study within the Information Network of Departments of Dermatology. Results Altogether, 2042 patients were patch tested. PPD 1% pet. yielded 6.0% positive reactions (n = 123), and PPD 0.3% pet. yielded 4.7% (n = 95). The synchronous reproducibility of PPD reactions was similar as known from parallel patch tests with identical PPD concentrations. The diagnostic properties of PPD 0.3% pet. expressed as reaction index and positivity ratio were good. Of the 123 patients reacting to PPD 1% pet., 32 (26%) had no positive reaction to PPD 0.3% pet. In 22 of these 32 patients (69%), no clinical relevance could be found. Conclusions As patch testing with PPD 0.3% pet. is reliable according to our results, we recommend replacing PPD 1% pet. in the baseline series with PPD 0.3% pet. active sensitization CAS 106-50-3 monitoring of contact allergy p-phenylenediamine patch test concentration patch testing Ballmer-Weber, Barbara K. verfasserin (DE-588)124756646 (DE-627)365723495 (DE-576)294484930 aut Dickel, Heinrich 1967- verfasserin (DE-588)142232963 (DE-627)704176289 (DE-576)329633902 aut Frosch, Peter J. 1946- verfasserin (DE-588)11547076X (DE-627)077272412 (DE-576)289901669 aut Bircher, Andreas 1953- verfasserin (DE-588)1173755977 (DE-627)1043604685 (DE-576)515683760 aut Weisshaar, Elke verfasserin (DE-588)1032807369 (DE-627)739344870 (DE-576)271388579 aut Hillen, Uwe verfasserin (DE-588)1171177216 (DE-627)1040422977 (DE-576)513635297 aut Enthalten in Contact dermatitis Oxford [u.a.] : Wiley-Blackwell, 1975 69(2013), Seite 26-31 Online-Ressource (DE-627)32448464X (DE-600)2027120-7 (DE-576)093888872 1600-0536 nnns volume:69 year:2013 pages:26-31 extent:6 https://doi.org/https://doi.org/10.1111/cod.12075 Verlag Resolving-System lizenzpflichtig Volltext https://www.onlinelibrary.wiley.com/doi/abs/10.1111/cod.12075 Verlag lizenzpflichtig Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_266 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 69 2013 26-31 6 2013 01 DE-16-250 3848293927 00 --%%-- --%%-- --%%-- --%%-- l01 03-02-21 2013 01 DE-16-250 00 s hd2013 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_7 2013 01 DE-16-250 03 s s_6 2013 01 DE-16-250 04 p (DE-627)1450298214 Weisshaar, Elke 2013 01 DE-16-250 04 k (DE-627)1416741372 Universitäts-Hautklinik 2013 01 DE-16-250 04 k (DE-627)1416466967 Medizinische Fakultät Heidelberg 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_6 |
| allfields_unstemmed |
10.1111/cod.12075 doi (DE-627)1747185582 (DE-599)KXP1747185582 (OCoLC)1341390284 DE-627 ger DE-627 rda eng Geier, Johannes verfasserin (DE-588)1118656563 (DE-627)872168395 (DE-576)479581622 aut Monitoring contact sensitization to p-phenylenediamine (PPD) by patch testing with PPD 0.3 % in petrolatum Johannes Geier, Barbara K. Ballmer‐Weber, Heinrich Dickel, Peter J. Frosch, Andreas Bircher, Elke Weisshaar and Uwe Hillen 19 June 2013 6 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Gesehen am 03.02.2020 Background Being a contact allergen of general relevance, p-phenylenediamine (PPD) is patch tested in the baseline series. However, PPD 1% in petrolatum may actively sensitize. Patch testing with PPD at 0.35% pet. proved to be safe, as far as active sensitization is concerned. Objectives To determine whether PPD 0.3% pet. reliably detects PPD sensitization. Methods Patch testing with PPD 0.3% pet. and 1% pet. synchronously was performed in consecutive patients in a multicentre study within the Information Network of Departments of Dermatology. Results Altogether, 2042 patients were patch tested. PPD 1% pet. yielded 6.0% positive reactions (n = 123), and PPD 0.3% pet. yielded 4.7% (n = 95). The synchronous reproducibility of PPD reactions was similar as known from parallel patch tests with identical PPD concentrations. The diagnostic properties of PPD 0.3% pet. expressed as reaction index and positivity ratio were good. Of the 123 patients reacting to PPD 1% pet., 32 (26%) had no positive reaction to PPD 0.3% pet. In 22 of these 32 patients (69%), no clinical relevance could be found. Conclusions As patch testing with PPD 0.3% pet. is reliable according to our results, we recommend replacing PPD 1% pet. in the baseline series with PPD 0.3% pet. active sensitization CAS 106-50-3 monitoring of contact allergy p-phenylenediamine patch test concentration patch testing Ballmer-Weber, Barbara K. verfasserin (DE-588)124756646 (DE-627)365723495 (DE-576)294484930 aut Dickel, Heinrich 1967- verfasserin (DE-588)142232963 (DE-627)704176289 (DE-576)329633902 aut Frosch, Peter J. 1946- verfasserin (DE-588)11547076X (DE-627)077272412 (DE-576)289901669 aut Bircher, Andreas 1953- verfasserin (DE-588)1173755977 (DE-627)1043604685 (DE-576)515683760 aut Weisshaar, Elke verfasserin (DE-588)1032807369 (DE-627)739344870 (DE-576)271388579 aut Hillen, Uwe verfasserin (DE-588)1171177216 (DE-627)1040422977 (DE-576)513635297 aut Enthalten in Contact dermatitis Oxford [u.a.] : Wiley-Blackwell, 1975 69(2013), Seite 26-31 Online-Ressource (DE-627)32448464X (DE-600)2027120-7 (DE-576)093888872 1600-0536 nnns volume:69 year:2013 pages:26-31 extent:6 https://doi.org/https://doi.org/10.1111/cod.12075 Verlag Resolving-System lizenzpflichtig Volltext https://www.onlinelibrary.wiley.com/doi/abs/10.1111/cod.12075 Verlag lizenzpflichtig Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_266 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 69 2013 26-31 6 2013 01 DE-16-250 3848293927 00 --%%-- --%%-- --%%-- --%%-- l01 03-02-21 2013 01 DE-16-250 00 s hd2013 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_7 2013 01 DE-16-250 03 s s_6 2013 01 DE-16-250 04 p (DE-627)1450298214 Weisshaar, Elke 2013 01 DE-16-250 04 k (DE-627)1416741372 Universitäts-Hautklinik 2013 01 DE-16-250 04 k (DE-627)1416466967 Medizinische Fakultät Heidelberg 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_6 |
| allfieldsGer |
10.1111/cod.12075 doi (DE-627)1747185582 (DE-599)KXP1747185582 (OCoLC)1341390284 DE-627 ger DE-627 rda eng Geier, Johannes verfasserin (DE-588)1118656563 (DE-627)872168395 (DE-576)479581622 aut Monitoring contact sensitization to p-phenylenediamine (PPD) by patch testing with PPD 0.3 % in petrolatum Johannes Geier, Barbara K. Ballmer‐Weber, Heinrich Dickel, Peter J. Frosch, Andreas Bircher, Elke Weisshaar and Uwe Hillen 19 June 2013 6 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Gesehen am 03.02.2020 Background Being a contact allergen of general relevance, p-phenylenediamine (PPD) is patch tested in the baseline series. However, PPD 1% in petrolatum may actively sensitize. Patch testing with PPD at 0.35% pet. proved to be safe, as far as active sensitization is concerned. Objectives To determine whether PPD 0.3% pet. reliably detects PPD sensitization. Methods Patch testing with PPD 0.3% pet. and 1% pet. synchronously was performed in consecutive patients in a multicentre study within the Information Network of Departments of Dermatology. Results Altogether, 2042 patients were patch tested. PPD 1% pet. yielded 6.0% positive reactions (n = 123), and PPD 0.3% pet. yielded 4.7% (n = 95). The synchronous reproducibility of PPD reactions was similar as known from parallel patch tests with identical PPD concentrations. The diagnostic properties of PPD 0.3% pet. expressed as reaction index and positivity ratio were good. Of the 123 patients reacting to PPD 1% pet., 32 (26%) had no positive reaction to PPD 0.3% pet. In 22 of these 32 patients (69%), no clinical relevance could be found. Conclusions As patch testing with PPD 0.3% pet. is reliable according to our results, we recommend replacing PPD 1% pet. in the baseline series with PPD 0.3% pet. active sensitization CAS 106-50-3 monitoring of contact allergy p-phenylenediamine patch test concentration patch testing Ballmer-Weber, Barbara K. verfasserin (DE-588)124756646 (DE-627)365723495 (DE-576)294484930 aut Dickel, Heinrich 1967- verfasserin (DE-588)142232963 (DE-627)704176289 (DE-576)329633902 aut Frosch, Peter J. 1946- verfasserin (DE-588)11547076X (DE-627)077272412 (DE-576)289901669 aut Bircher, Andreas 1953- verfasserin (DE-588)1173755977 (DE-627)1043604685 (DE-576)515683760 aut Weisshaar, Elke verfasserin (DE-588)1032807369 (DE-627)739344870 (DE-576)271388579 aut Hillen, Uwe verfasserin (DE-588)1171177216 (DE-627)1040422977 (DE-576)513635297 aut Enthalten in Contact dermatitis Oxford [u.a.] : Wiley-Blackwell, 1975 69(2013), Seite 26-31 Online-Ressource (DE-627)32448464X (DE-600)2027120-7 (DE-576)093888872 1600-0536 nnns volume:69 year:2013 pages:26-31 extent:6 https://doi.org/https://doi.org/10.1111/cod.12075 Verlag Resolving-System lizenzpflichtig Volltext https://www.onlinelibrary.wiley.com/doi/abs/10.1111/cod.12075 Verlag lizenzpflichtig Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_266 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 69 2013 26-31 6 2013 01 DE-16-250 3848293927 00 --%%-- --%%-- --%%-- --%%-- l01 03-02-21 2013 01 DE-16-250 00 s hd2013 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_7 2013 01 DE-16-250 03 s s_6 2013 01 DE-16-250 04 p (DE-627)1450298214 Weisshaar, Elke 2013 01 DE-16-250 04 k (DE-627)1416741372 Universitäts-Hautklinik 2013 01 DE-16-250 04 k (DE-627)1416466967 Medizinische Fakultät Heidelberg 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_6 |
| allfieldsSound |
10.1111/cod.12075 doi (DE-627)1747185582 (DE-599)KXP1747185582 (OCoLC)1341390284 DE-627 ger DE-627 rda eng Geier, Johannes verfasserin (DE-588)1118656563 (DE-627)872168395 (DE-576)479581622 aut Monitoring contact sensitization to p-phenylenediamine (PPD) by patch testing with PPD 0.3 % in petrolatum Johannes Geier, Barbara K. Ballmer‐Weber, Heinrich Dickel, Peter J. Frosch, Andreas Bircher, Elke Weisshaar and Uwe Hillen 19 June 2013 6 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Gesehen am 03.02.2020 Background Being a contact allergen of general relevance, p-phenylenediamine (PPD) is patch tested in the baseline series. However, PPD 1% in petrolatum may actively sensitize. Patch testing with PPD at 0.35% pet. proved to be safe, as far as active sensitization is concerned. Objectives To determine whether PPD 0.3% pet. reliably detects PPD sensitization. Methods Patch testing with PPD 0.3% pet. and 1% pet. synchronously was performed in consecutive patients in a multicentre study within the Information Network of Departments of Dermatology. Results Altogether, 2042 patients were patch tested. PPD 1% pet. yielded 6.0% positive reactions (n = 123), and PPD 0.3% pet. yielded 4.7% (n = 95). The synchronous reproducibility of PPD reactions was similar as known from parallel patch tests with identical PPD concentrations. The diagnostic properties of PPD 0.3% pet. expressed as reaction index and positivity ratio were good. Of the 123 patients reacting to PPD 1% pet., 32 (26%) had no positive reaction to PPD 0.3% pet. In 22 of these 32 patients (69%), no clinical relevance could be found. Conclusions As patch testing with PPD 0.3% pet. is reliable according to our results, we recommend replacing PPD 1% pet. in the baseline series with PPD 0.3% pet. active sensitization CAS 106-50-3 monitoring of contact allergy p-phenylenediamine patch test concentration patch testing Ballmer-Weber, Barbara K. verfasserin (DE-588)124756646 (DE-627)365723495 (DE-576)294484930 aut Dickel, Heinrich 1967- verfasserin (DE-588)142232963 (DE-627)704176289 (DE-576)329633902 aut Frosch, Peter J. 1946- verfasserin (DE-588)11547076X (DE-627)077272412 (DE-576)289901669 aut Bircher, Andreas 1953- verfasserin (DE-588)1173755977 (DE-627)1043604685 (DE-576)515683760 aut Weisshaar, Elke verfasserin (DE-588)1032807369 (DE-627)739344870 (DE-576)271388579 aut Hillen, Uwe verfasserin (DE-588)1171177216 (DE-627)1040422977 (DE-576)513635297 aut Enthalten in Contact dermatitis Oxford [u.a.] : Wiley-Blackwell, 1975 69(2013), Seite 26-31 Online-Ressource (DE-627)32448464X (DE-600)2027120-7 (DE-576)093888872 1600-0536 nnns volume:69 year:2013 pages:26-31 extent:6 https://doi.org/https://doi.org/10.1111/cod.12075 Verlag Resolving-System lizenzpflichtig Volltext https://www.onlinelibrary.wiley.com/doi/abs/10.1111/cod.12075 Verlag lizenzpflichtig Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_120 GBV_ILN_138 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_266 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_636 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2018 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2093 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2472 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_2548 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 69 2013 26-31 6 2013 01 DE-16-250 3848293927 00 --%%-- --%%-- --%%-- --%%-- l01 03-02-21 2013 01 DE-16-250 00 s hd2013 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_7 2013 01 DE-16-250 03 s s_6 2013 01 DE-16-250 04 p (DE-627)1450298214 Weisshaar, Elke 2013 01 DE-16-250 04 k (DE-627)1416741372 Universitäts-Hautklinik 2013 01 DE-16-250 04 k (DE-627)1416466967 Medizinische Fakultät Heidelberg 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_6 |
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Geier, Johannes @@aut@@ Ballmer-Weber, Barbara K. @@aut@@ Dickel, Heinrich @@aut@@ Frosch, Peter J. @@aut@@ Bircher, Andreas @@aut@@ Weisshaar, Elke @@aut@@ Hillen, Uwe @@aut@@ |
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Ballmer‐Weber, Heinrich Dickel, Peter J. 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However, PPD 1% in petrolatum may actively sensitize. Patch testing with PPD at 0.35% pet. proved to be safe, as far as active sensitization is concerned. Objectives To determine whether PPD 0.3% pet. reliably detects PPD sensitization. Methods Patch testing with PPD 0.3% pet. and 1% pet. synchronously was performed in consecutive patients in a multicentre study within the Information Network of Departments of Dermatology. Results Altogether, 2042 patients were patch tested. PPD 1% pet. yielded 6.0% positive reactions (n = 123), and PPD 0.3% pet. yielded 4.7% (n = 95). The synchronous reproducibility of PPD reactions was similar as known from parallel patch tests with identical PPD concentrations. The diagnostic properties of PPD 0.3% pet. expressed as reaction index and positivity ratio were good. Of the 123 patients reacting to PPD 1% pet., 32 (26%) had no positive reaction to PPD 0.3% pet. In 22 of these 32 patients (69%), no clinical relevance could be found. 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Monitoring contact sensitization to p-phenylenediamine (PPD) by patch testing with PPD 0.3 % in petrolatum Johannes Geier, Barbara K. Ballmer‐Weber, Heinrich Dickel, Peter J. Frosch, Andreas Bircher, Elke Weisshaar and Uwe Hillen |
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monitoring contact sensitization to p-phenylenediamine (ppd) by patch testing with ppd 0.3 % in petrolatum |
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Monitoring contact sensitization to p-phenylenediamine (PPD) by patch testing with PPD 0.3 % in petrolatum |
| abstract |
Background Being a contact allergen of general relevance, p-phenylenediamine (PPD) is patch tested in the baseline series. However, PPD 1% in petrolatum may actively sensitize. Patch testing with PPD at 0.35% pet. proved to be safe, as far as active sensitization is concerned. Objectives To determine whether PPD 0.3% pet. reliably detects PPD sensitization. Methods Patch testing with PPD 0.3% pet. and 1% pet. synchronously was performed in consecutive patients in a multicentre study within the Information Network of Departments of Dermatology. Results Altogether, 2042 patients were patch tested. PPD 1% pet. yielded 6.0% positive reactions (n = 123), and PPD 0.3% pet. yielded 4.7% (n = 95). The synchronous reproducibility of PPD reactions was similar as known from parallel patch tests with identical PPD concentrations. The diagnostic properties of PPD 0.3% pet. expressed as reaction index and positivity ratio were good. Of the 123 patients reacting to PPD 1% pet., 32 (26%) had no positive reaction to PPD 0.3% pet. In 22 of these 32 patients (69%), no clinical relevance could be found. Conclusions As patch testing with PPD 0.3% pet. is reliable according to our results, we recommend replacing PPD 1% pet. in the baseline series with PPD 0.3% pet. Gesehen am 03.02.2020 |
| abstractGer |
Background Being a contact allergen of general relevance, p-phenylenediamine (PPD) is patch tested in the baseline series. However, PPD 1% in petrolatum may actively sensitize. Patch testing with PPD at 0.35% pet. proved to be safe, as far as active sensitization is concerned. Objectives To determine whether PPD 0.3% pet. reliably detects PPD sensitization. Methods Patch testing with PPD 0.3% pet. and 1% pet. synchronously was performed in consecutive patients in a multicentre study within the Information Network of Departments of Dermatology. Results Altogether, 2042 patients were patch tested. PPD 1% pet. yielded 6.0% positive reactions (n = 123), and PPD 0.3% pet. yielded 4.7% (n = 95). The synchronous reproducibility of PPD reactions was similar as known from parallel patch tests with identical PPD concentrations. The diagnostic properties of PPD 0.3% pet. expressed as reaction index and positivity ratio were good. Of the 123 patients reacting to PPD 1% pet., 32 (26%) had no positive reaction to PPD 0.3% pet. In 22 of these 32 patients (69%), no clinical relevance could be found. Conclusions As patch testing with PPD 0.3% pet. is reliable according to our results, we recommend replacing PPD 1% pet. in the baseline series with PPD 0.3% pet. Gesehen am 03.02.2020 |
| abstract_unstemmed |
Background Being a contact allergen of general relevance, p-phenylenediamine (PPD) is patch tested in the baseline series. However, PPD 1% in petrolatum may actively sensitize. Patch testing with PPD at 0.35% pet. proved to be safe, as far as active sensitization is concerned. Objectives To determine whether PPD 0.3% pet. reliably detects PPD sensitization. Methods Patch testing with PPD 0.3% pet. and 1% pet. synchronously was performed in consecutive patients in a multicentre study within the Information Network of Departments of Dermatology. Results Altogether, 2042 patients were patch tested. PPD 1% pet. yielded 6.0% positive reactions (n = 123), and PPD 0.3% pet. yielded 4.7% (n = 95). The synchronous reproducibility of PPD reactions was similar as known from parallel patch tests with identical PPD concentrations. The diagnostic properties of PPD 0.3% pet. expressed as reaction index and positivity ratio were good. Of the 123 patients reacting to PPD 1% pet., 32 (26%) had no positive reaction to PPD 0.3% pet. In 22 of these 32 patients (69%), no clinical relevance could be found. Conclusions As patch testing with PPD 0.3% pet. is reliable according to our results, we recommend replacing PPD 1% pet. in the baseline series with PPD 0.3% pet. Gesehen am 03.02.2020 |
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| title_short |
Monitoring contact sensitization to p-phenylenediamine (PPD) by patch testing with PPD 0.3 % in petrolatum |
| url |
https://doi.org/https://doi.org/10.1111/cod.12075 https://www.onlinelibrary.wiley.com/doi/abs/10.1111/cod.12075 |
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Ballmer-Weber, Barbara K. Dickel, Heinrich 1967- Frosch, Peter J. 1946- Bircher, Andreas 1953- Weisshaar, Elke Hillen, Uwe |
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Ballmer-Weber, Barbara K. Dickel, Heinrich 1967- Frosch, Peter J. 1946- Bircher, Andreas 1953- Weisshaar, Elke Hillen, Uwe |
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Geier, J. Geier, Johannes Weber, Barbara K. Ballmer- Weber, B. Ballmer- Ballmer-Weber, B. Ballmer-Weber, Barbara Ballmer-Weber, B. K. Ballmer-Weber, Barbara K. Dickel, Heinrich Frosch, Peter Frosch, P. J. Frosch, Peter J. Bircher, Andreas Jost Bircher, Andreas J. Bircher, Andreas Weisshaar, E. Weisshaar, Elke Hillen, U. Hillen, Uwe |
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Geier, J. Geier, Johannes Weber, Barbara K. Ballmer- Weber, B. Ballmer- Ballmer-Weber, B. Ballmer-Weber, Barbara Ballmer-Weber, B. K. Ballmer-Weber, Barbara K. Dickel, Heinrich Frosch, Peter Frosch, P. J. Frosch, Peter J. Bircher, Andreas Jost Bircher, Andreas J. Bircher, Andreas Weisshaar, E. Weisshaar, Elke Hillen, U. Hillen, Uwe |
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Geier, J. Geier, Johannes Weber, Barbara K. Ballmer- Weber, B. Ballmer- Ballmer-Weber, B. Ballmer-Weber, Barbara Ballmer-Weber, B. K. Ballmer-Weber, Barbara K. Dickel, Heinrich Frosch, Peter Frosch, P. J. Frosch, Peter J. Bircher, Andreas Jost Bircher, Andreas J. Bircher, Andreas Weisshaar, E. Weisshaar, Elke Hillen, U. Hillen, Uwe |
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2024-07-04T08:46:26.751Z |
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