Surgery versus conservative treatment for traumatic acute subdural haematoma : a prospective, multicentre, observational, comparative effectiveness study
Background - Despite being well established, acute surgery in traumatic acute subdural haematoma is based on low-grade evidence. We aimed to compare the effectiveness of a strategy preferring acute surgical evacuation with one preferring initial conservative treatment in acute subdural haematoma. -...
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
May 5, 2022 |
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| Anmerkung: |
Gesehen am 25.09.2022 CENTER-TBI Collaboration Group: Cecilia Åkerlund, Krisztina Amrein, Nada Andelic, Lasse Andreassen, Audny Anke, Anna Antoni, Gérard Audibert, Philippe Azouvi, Maria Luisa Azzolini, Ronald Bartels, Pál Barzó [und viele weitere] |
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| Umfang: |
12 |
| Übergeordnetes Werk: |
Enthalten in: The lancet - London : Lancet Publ. Group, 2002, 21(2022), 7 vom: Juli, Seite 620-631 |
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| Übergeordnetes Werk: |
volume:21 ; year:2022 ; number:7 ; month:07 ; pages:620-631 ; extent:12 |
| Links: |
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| DOI / URN: |
10.1016/S1474-4422(22)00166-1 |
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| Katalog-ID: |
1817370863 |
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| 100 | 1 | |a Essen, Thomas van |e verfasserin |0 (DE-588)1190840006 |0 (DE-627)1669416119 |4 aut | |
| 245 | 1 | 0 | |a Surgery versus conservative treatment for traumatic acute subdural haematoma |b a prospective, multicentre, observational, comparative effectiveness study |c Thomas A van Essen, Hester F Lingsma, Dana Pisică, Ranjit D Singh, Victor Volovici, Hugo F den Boogert, Alexander Younsi, Lianne D Peppel, Majanka H Heijenbrok-Kal, Gerard M Ribbers, Robert Walchenbach, David K Menon, Peter Hutchinson, Bart Depreitere, Ewout W Steyerberg, Andrew I R Maas, Godard C W de Ruiter, Wilco C Peul, on behalf of the CENTER-TBI Collaboration Group |
| 264 | 1 | |c May 5, 2022 | |
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| 500 | |a Gesehen am 25.09.2022 | ||
| 500 | |a CENTER-TBI Collaboration Group: Cecilia Åkerlund, Krisztina Amrein, Nada Andelic, Lasse Andreassen, Audny Anke, Anna Antoni, Gérard Audibert, Philippe Azouvi, Maria Luisa Azzolini, Ronald Bartels, Pál Barzó [und viele weitere] | ||
| 520 | |a Background - Despite being well established, acute surgery in traumatic acute subdural haematoma is based on low-grade evidence. We aimed to compare the effectiveness of a strategy preferring acute surgical evacuation with one preferring initial conservative treatment in acute subdural haematoma. - Methods - We did a prospective, observational, comparative effectiveness study using data from participants enrolled in the Collaborative European Neurotrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) cohort. We included patients with no pre-existing severe neurological disorders who presented with acute subdural haematoma within 24 h of traumatic brain injury. Using an instrumental variable analysis, we compared outcomes between centres according to treatment preference for acute subdural haematoma (acute surgical evacuation or initial conservative treatment), measured by the case-mix-adjusted percentage of acute surgery per centre. The primary endpoint was functional outcome at 6 months as rated with the Glasgow Outcome Scale Extended, which was estimated with ordinal regression as a common odds ratio (OR) and adjusted for prespecified confounders. Variation in centre preference was quantified with the median OR (MOR). CENTER-TBI is registered with ClinicalTrials.gov, number NCT02210221, and the Resource Identification Portal (Research Resource Identifier SCR_015582). - Findings - Between Dec 19, 2014 and Dec 17, 2017, 4559 patients with traumatic brain injury were enrolled in CENTER-TBI, of whom 1407 (31%) presented with acute subdural haematoma and were included in our study. Acute surgical evacuation was done in 336 (24%) patients, by craniotomy in 245 (73%) of those patients and by decompressive craniectomy in 91 (27%). Delayed decompressive craniectomy or craniotomy after initial conservative treatment (n=982) occurred in 107 (11%) patients. The percentage of patients who underwent acute surgery ranged from 5·6% to 51·5% (IQR 12·3-35·9) between centres, with a two-times higher probability of receiving acute surgery for an identical patient in one centre versus another centre at random (adjusted MOR for acute surgery 1·8; p<0·0001]). Centre preference for acute surgery over initial conservative treatment was not associated with improvements in functional outcome (common OR per 23·6% [IQR increase] more acute surgery in a centre 0·92, 95% CI 0·77-1·09). - Interpretation - Our findings show that treatment for patients with acute subdural haematoma with similar characteristics differed depending on the treating centre, because of variation in the preferred approach. A treatment strategy preferring an aggressive approach of acute surgical evacuation over initial conservative treatment was not associated with better functional outcome. Therefore, in a patient with acute subdural haematoma for whom a neurosurgeon sees no clear superiority for acute surgery over conservative treatment, initial conservative treatment might be considered. - Funding - The Hersenstichting Nederland (also known as the Dutch Brain Foundation), the European Commission Seventh Framework Programme, the Hannelore Kohl Stiftung (Germany), OneMind (USA), Integra LifeSciences Corporation (USA), and NeuroTrauma Sciences (USA). | ||
| 700 | 1 | |a Lingsma, Hester F |e verfasserin |4 aut | |
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| 700 | 1 | |a Singh, Ranjit D |e verfasserin |4 aut | |
| 700 | 1 | |a Volovici, Victor |e verfasserin |4 aut | |
| 700 | 1 | |a den Boogert, Hugo F |e verfasserin |4 aut | |
| 700 | 1 | |a Younsi, Alexander |d 1985- |e verfasserin |0 (DE-588)104607508X |0 (DE-627)775681547 |0 (DE-576)39935882X |4 aut | |
| 700 | 1 | |a Peppel, Lianne D |e verfasserin |4 aut | |
| 700 | 1 | |a Heijenbrok-Kal, Majanka H |e verfasserin |4 aut | |
| 700 | 1 | |a Ribbers, Gerard M |e verfasserin |4 aut | |
| 700 | 1 | |a Walchenbach, Robert |e verfasserin |4 aut | |
| 700 | 1 | |a Menon, David K |e verfasserin |4 aut | |
| 700 | 1 | |a Hutchinson, Peter |e verfasserin |4 aut | |
| 700 | 1 | |a Depreitere, Bart |e verfasserin |4 aut | |
| 700 | 1 | |a Steyerberg, Ewout W |e verfasserin |4 aut | |
| 700 | 1 | |a Maas, Andrew I R |e verfasserin |4 aut | |
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10.1016/S1474-4422(22)00166-1 doi (DE-627)1817370863 (DE-599)KXP1817370863 (OCoLC)1361696287 DE-627 ger DE-627 rda eng Essen, Thomas van verfasserin (DE-588)1190840006 (DE-627)1669416119 aut Surgery versus conservative treatment for traumatic acute subdural haematoma a prospective, multicentre, observational, comparative effectiveness study Thomas A van Essen, Hester F Lingsma, Dana Pisică, Ranjit D Singh, Victor Volovici, Hugo F den Boogert, Alexander Younsi, Lianne D Peppel, Majanka H Heijenbrok-Kal, Gerard M Ribbers, Robert Walchenbach, David K Menon, Peter Hutchinson, Bart Depreitere, Ewout W Steyerberg, Andrew I R Maas, Godard C W de Ruiter, Wilco C Peul, on behalf of the CENTER-TBI Collaboration Group May 5, 2022 12 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Gesehen am 25.09.2022 CENTER-TBI Collaboration Group: Cecilia Åkerlund, Krisztina Amrein, Nada Andelic, Lasse Andreassen, Audny Anke, Anna Antoni, Gérard Audibert, Philippe Azouvi, Maria Luisa Azzolini, Ronald Bartels, Pál Barzó [und viele weitere] Background - Despite being well established, acute surgery in traumatic acute subdural haematoma is based on low-grade evidence. We aimed to compare the effectiveness of a strategy preferring acute surgical evacuation with one preferring initial conservative treatment in acute subdural haematoma. - Methods - We did a prospective, observational, comparative effectiveness study using data from participants enrolled in the Collaborative European Neurotrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) cohort. We included patients with no pre-existing severe neurological disorders who presented with acute subdural haematoma within 24 h of traumatic brain injury. Using an instrumental variable analysis, we compared outcomes between centres according to treatment preference for acute subdural haematoma (acute surgical evacuation or initial conservative treatment), measured by the case-mix-adjusted percentage of acute surgery per centre. The primary endpoint was functional outcome at 6 months as rated with the Glasgow Outcome Scale Extended, which was estimated with ordinal regression as a common odds ratio (OR) and adjusted for prespecified confounders. Variation in centre preference was quantified with the median OR (MOR). CENTER-TBI is registered with ClinicalTrials.gov, number NCT02210221, and the Resource Identification Portal (Research Resource Identifier SCR_015582). - Findings - Between Dec 19, 2014 and Dec 17, 2017, 4559 patients with traumatic brain injury were enrolled in CENTER-TBI, of whom 1407 (31%) presented with acute subdural haematoma and were included in our study. Acute surgical evacuation was done in 336 (24%) patients, by craniotomy in 245 (73%) of those patients and by decompressive craniectomy in 91 (27%). Delayed decompressive craniectomy or craniotomy after initial conservative treatment (n=982) occurred in 107 (11%) patients. The percentage of patients who underwent acute surgery ranged from 5·6% to 51·5% (IQR 12·3-35·9) between centres, with a two-times higher probability of receiving acute surgery for an identical patient in one centre versus another centre at random (adjusted MOR for acute surgery 1·8; p<0·0001]). Centre preference for acute surgery over initial conservative treatment was not associated with improvements in functional outcome (common OR per 23·6% [IQR increase] more acute surgery in a centre 0·92, 95% CI 0·77-1·09). - Interpretation - Our findings show that treatment for patients with acute subdural haematoma with similar characteristics differed depending on the treating centre, because of variation in the preferred approach. A treatment strategy preferring an aggressive approach of acute surgical evacuation over initial conservative treatment was not associated with better functional outcome. Therefore, in a patient with acute subdural haematoma for whom a neurosurgeon sees no clear superiority for acute surgery over conservative treatment, initial conservative treatment might be considered. - Funding - The Hersenstichting Nederland (also known as the Dutch Brain Foundation), the European Commission Seventh Framework Programme, the Hannelore Kohl Stiftung (Germany), OneMind (USA), Integra LifeSciences Corporation (USA), and NeuroTrauma Sciences (USA). Lingsma, Hester F verfasserin aut Pisică, Dana verfasserin aut Singh, Ranjit D verfasserin aut Volovici, Victor verfasserin aut den Boogert, Hugo F verfasserin aut Younsi, Alexander 1985- verfasserin (DE-588)104607508X (DE-627)775681547 (DE-576)39935882X aut Peppel, Lianne D verfasserin aut Heijenbrok-Kal, Majanka H verfasserin aut Ribbers, Gerard M verfasserin aut Walchenbach, Robert verfasserin aut Menon, David K verfasserin aut Hutchinson, Peter verfasserin aut Depreitere, Bart verfasserin aut Steyerberg, Ewout W verfasserin aut Maas, Andrew I R verfasserin aut de Ruiter, Godard C W verfasserin aut Peul, Wilco C verfasserin aut Åkerlund, Cecilia verfasserin aut Amrein, Krisztina verfasserin aut Andelic, Nada verfasserin aut Andreassen, Lasse verfasserin aut Anke, Audny verfasserin aut Antoni, Anna verfasserin aut Audibert, Gérard verfasserin aut Azouvi, Philippe verfasserin aut Azzolini, Maria Luisa verfasserin aut Bartels, Ronald verfasserin aut Barzó, Pál verfasserin aut Beauvais, Romuald verfasserin aut Beer, Ronny verfasserin aut Bellander, Bo-Michael verfasserin aut Belli, Antonio verfasserin aut Benali, Habib verfasserin aut Berardino, Maurizio verfasserin aut Beretta, Luigi verfasserin aut Blaabjerg, Morten verfasserin aut Bragge, Peter verfasserin aut Brazinova, Alexandra verfasserin aut Brinck, Vibeke verfasserin aut Brooker, Joanne verfasserin aut Brorsson, Camilla verfasserin aut Buki, Andras verfasserin aut Bullinger, Monika verfasserin aut Cabeleira, Manuel verfasserin aut Caccioppola, Alessio verfasserin aut Calappi, Emiliana verfasserin aut Calvi, Maria Rosa verfasserin aut Cameron, Peter verfasserin aut Carbayo Lozano, Guillermo verfasserin aut Carbonara, Marco verfasserin aut Castaño-León, Ana M. verfasserin aut Cavallo, Simona verfasserin aut Chevallard, Giorgio verfasserin aut Chieregato, Arturo verfasserin aut Citerio, Giuseppe verfasserin aut Clusmann, Hans verfasserin aut Coburn, Mark Steven verfasserin aut Coles, Jonathan verfasserin aut Cooper, Jamie D. verfasserin aut Correia, Marta verfasserin aut Čović, Amra verfasserin aut Curry, Nicola verfasserin aut Czeiter, Endre verfasserin aut Czosnyka, Marek verfasserin aut Dahyot-Fizelier, Claire verfasserin aut Dark, Paul verfasserin aut Dawes, Helen verfasserin aut De Keyser, Véronique verfasserin aut Degos, Vincent verfasserin aut Della Corte, Francesco verfasserin aut Đilvesi, Đula verfasserin aut Dixit, Abhishek verfasserin aut Donoghue, Emma verfasserin aut Dreier, Jens verfasserin aut Dulière, Guy-Loup verfasserin aut Ercole, Ari verfasserin aut Esser, Patrick verfasserin aut Ezer, Erzsébet verfasserin aut Fabricius, Martin verfasserin aut Feigin, Valery L. verfasserin aut Foks, Kelly verfasserin aut Frisvold, Shirin verfasserin aut Furmanov, Alex verfasserin aut Gagliardo, Pablo verfasserin aut Galanaud, Damien verfasserin aut Gantner, Dashiell verfasserin aut Gao, Guoyi verfasserin aut George, Pradeep verfasserin aut Ghuysen, Alexandre verfasserin aut Giga, Lelde verfasserin aut Glocker, Ben verfasserin aut Golubović, Jagoš verfasserin aut Gomez, Pedro A. verfasserin aut Gratz, Johannes verfasserin aut Gravesteijn, Benjamin verfasserin aut Grossi, Francesca verfasserin aut Gruen, Russell L. verfasserin aut Gupta, Deepak verfasserin aut Haagsma, Juanita A. verfasserin aut Haitsma, Iain verfasserin aut Helbok, Raimund verfasserin aut Helseth, Eirik verfasserin aut Horton, Lindsay verfasserin aut Huijben, Jilske verfasserin aut Jacobs, Bram verfasserin aut Jankowski, Stefan verfasserin aut Jarrett, Mike verfasserin aut Jiang, Ji-yao verfasserin aut Johnson, Faye verfasserin aut Jones, Kelly verfasserin aut Karan, Mladen verfasserin aut Kolias, Angelos G. verfasserin aut Kompanje, Erwin verfasserin aut Kondziella, Daniel verfasserin aut Kornaropoulos, Evgenios verfasserin aut Koskinen, Lars-Owe verfasserin aut Kovács, Noémi verfasserin aut Lagares, Alfonso verfasserin aut Lanyon, Linda verfasserin aut Laureys, Steven verfasserin aut Lecky, Fiona verfasserin aut Ledoux, Didier verfasserin aut Lefering, Rolf verfasserin aut Legrand, Valerie verfasserin aut Lejeune, Aurelie verfasserin aut Levi, Leon verfasserin aut Lightfoot, Roger verfasserin aut Maegele, Marc verfasserin aut Majdan, Marek verfasserin aut Manara, Alex verfasserin aut Manley, Geoffrey verfasserin aut Maréchal, Hugues verfasserin aut Martino, Costanza verfasserin aut Mattern, Julia verfasserin aut McMahon, Catherine verfasserin aut Melegh, Béla verfasserin aut Menovsky, Tomas verfasserin aut Mikolic, Ana verfasserin aut Misset, Benoit verfasserin aut Muraleedharan, Visakh verfasserin aut Murray, Lynnette verfasserin aut Nair, Nandesh verfasserin aut Negru, Ancuta verfasserin aut Nelson, David verfasserin aut Newcombe, Virginia verfasserin aut Nieboer, Daan verfasserin aut Nyirádi, József verfasserin aut Oresic, Matej verfasserin aut Ortolano, Fabrizio verfasserin aut Otesile, Olubukola verfasserin aut Palotie, Aarno verfasserin aut Parizel, Paul M. verfasserin aut Payen, Jean-François verfasserin aut Perera, Natascha verfasserin aut Perlbarg, Vincent verfasserin aut Persona, Paolo verfasserin aut Piippo-Karjalainen, Anna verfasserin aut Pirinen, Matti verfasserin aut Ples, Horia verfasserin aut Polinder, Suzanne verfasserin aut Pomposo, Inigo verfasserin aut Posti, Jussi P. verfasserin aut Puybasset, Louis verfasserin aut Rădoi, Andreea verfasserin aut Ragauskas, Arminas verfasserin aut Raj, Rahul verfasserin aut Rambadagalla, Malinka verfasserin aut Rehorčíková, Veronika verfasserin aut Retel Helmrich, Isabel verfasserin aut Rhodes, Jonathan verfasserin aut Richardson, Sylvia verfasserin aut Richter, Sophie verfasserin aut Ripatti, Samuli verfasserin aut Rocka, Saulius verfasserin aut Roe, Cecilie verfasserin aut Roise, Olav verfasserin aut Rosand, Jonathan verfasserin aut Rosenfeld, Jeffrey verfasserin aut Rosenlund, Christina verfasserin aut Rosenthal, Guy verfasserin aut Rossaint, Rolf verfasserin aut Rossi, Sandra verfasserin aut Rueckert, Daniel verfasserin aut Rusnák, Martin verfasserin aut Sahuquillo, Juan verfasserin aut Sakowitz, Oliver verfasserin aut Sanchez-Porras, Renan verfasserin aut Sandor, Janos verfasserin aut Schäfer, Nadine verfasserin aut Schmidt, Silke verfasserin aut Schoechl, Herbert verfasserin aut Schoonman, Guus verfasserin aut Schou, Rico Frederik verfasserin aut Schwendenwein, Elisabeth verfasserin aut Sewalt, Charlie verfasserin aut Skandsen, Toril verfasserin aut Smielewski, Peter verfasserin aut Sorinola, Abayomi verfasserin aut Stamatakis, Emmanuel verfasserin aut Stanworth, Simon verfasserin aut Kowark, Ana verfasserin aut Stevens, Robert verfasserin aut Stewart, William verfasserin aut Stocchetti, Nino verfasserin aut Sundström, Nina verfasserin aut Takala, Riikka verfasserin aut Tamás, Viktória verfasserin aut Tamosuitis, Tomas verfasserin aut Taylor, Mark Steven verfasserin aut Te Ao, Braden verfasserin aut Tenovuo, Olli verfasserin aut Theadom, Alice verfasserin aut Thomas, Matt verfasserin aut Tibboel, Dick verfasserin aut Timmers, Marjolijn verfasserin aut Tolias, Christos verfasserin aut Trapani, Tony verfasserin aut Tudora, Cristina Maria verfasserin aut Unterberg, Andreas verfasserin aut Vajkoczy, Peter verfasserin aut Valeinis, Egils verfasserin aut Vallance, Shirley verfasserin aut Vámos, Zoltán verfasserin aut Van der Jagt, Mathieu verfasserin aut van der Naalt, Joukje verfasserin aut Van der Steen, Gregory verfasserin aut van Dijck, Jeroen T. J. M. verfasserin aut Van Hecke, Wim verfasserin aut van Heugten, Caroline verfasserin aut Van Praag, Dominique verfasserin aut Van Veen, Ernest verfasserin aut van Wijk, Roel verfasserin aut Vande Vyvere, Thijs verfasserin aut Vargiolu, Alessia verfasserin aut Vega, Emmanuel verfasserin aut Velt, Kimberley verfasserin aut Verheyden, Jan verfasserin aut Vespa, Paul M. verfasserin aut Vik, Anne verfasserin aut Vilcinis, Rimantas verfasserin aut von Steinbüchel, Nicole verfasserin aut Voormolen, Daphne verfasserin aut Vulekovic, Petar verfasserin aut Wang, Kevin K. W. verfasserin aut Wiegers, Eveline verfasserin aut Williams, Guy verfasserin aut Wilson, Lindsay verfasserin aut Winzeck, Stefan verfasserin aut Wolf, Stefan verfasserin aut Yang, Zhihui verfasserin aut Ylén, Peter verfasserin aut Zeiler, Frederick A. verfasserin aut Ziverte, Agate verfasserin aut Zoerle, Tommaso verfasserin aut Enthalten in The lancet London : Lancet Publ. Group, 2002 21(2022), 7 vom: Juli, Seite 620-631 Online-Ressource (DE-627)348587104 (DE-600)2079704-7 (DE-576)110736362 1474-4465 nnns volume:21 year:2022 number:7 month:07 pages:620-631 extent:12 https://doi.org/10.1016/S1474-4422(22)00166-1 Verlag Resolving-System lizenzpflichtig Volltext https://www.sciencedirect.com/science/article/pii/S1474442222001661 Verlag lizenzpflichtig Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 21 2022 7 7 620-631 12 2013 01 DE-16-250 4191345133 00 --%%-- --%%-- --%%-- --%%-- l01 25-09-22 2013 01 DE-16-250 00 s hd2022 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_255 2013 01 DE-16-250 03 s s_12 2013 01 DE-16-250 04 p (DE-627)1493914448 Younsi, Alexander 2013 01 DE-16-250 04 k (DE-627)141674133X Neurochirurgische Universitätsklinik 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_7 |
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10.1016/S1474-4422(22)00166-1 doi (DE-627)1817370863 (DE-599)KXP1817370863 (OCoLC)1361696287 DE-627 ger DE-627 rda eng Essen, Thomas van verfasserin (DE-588)1190840006 (DE-627)1669416119 aut Surgery versus conservative treatment for traumatic acute subdural haematoma a prospective, multicentre, observational, comparative effectiveness study Thomas A van Essen, Hester F Lingsma, Dana Pisică, Ranjit D Singh, Victor Volovici, Hugo F den Boogert, Alexander Younsi, Lianne D Peppel, Majanka H Heijenbrok-Kal, Gerard M Ribbers, Robert Walchenbach, David K Menon, Peter Hutchinson, Bart Depreitere, Ewout W Steyerberg, Andrew I R Maas, Godard C W de Ruiter, Wilco C Peul, on behalf of the CENTER-TBI Collaboration Group May 5, 2022 12 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Gesehen am 25.09.2022 CENTER-TBI Collaboration Group: Cecilia Åkerlund, Krisztina Amrein, Nada Andelic, Lasse Andreassen, Audny Anke, Anna Antoni, Gérard Audibert, Philippe Azouvi, Maria Luisa Azzolini, Ronald Bartels, Pál Barzó [und viele weitere] Background - Despite being well established, acute surgery in traumatic acute subdural haematoma is based on low-grade evidence. We aimed to compare the effectiveness of a strategy preferring acute surgical evacuation with one preferring initial conservative treatment in acute subdural haematoma. - Methods - We did a prospective, observational, comparative effectiveness study using data from participants enrolled in the Collaborative European Neurotrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) cohort. We included patients with no pre-existing severe neurological disorders who presented with acute subdural haematoma within 24 h of traumatic brain injury. Using an instrumental variable analysis, we compared outcomes between centres according to treatment preference for acute subdural haematoma (acute surgical evacuation or initial conservative treatment), measured by the case-mix-adjusted percentage of acute surgery per centre. The primary endpoint was functional outcome at 6 months as rated with the Glasgow Outcome Scale Extended, which was estimated with ordinal regression as a common odds ratio (OR) and adjusted for prespecified confounders. Variation in centre preference was quantified with the median OR (MOR). CENTER-TBI is registered with ClinicalTrials.gov, number NCT02210221, and the Resource Identification Portal (Research Resource Identifier SCR_015582). - Findings - Between Dec 19, 2014 and Dec 17, 2017, 4559 patients with traumatic brain injury were enrolled in CENTER-TBI, of whom 1407 (31%) presented with acute subdural haematoma and were included in our study. Acute surgical evacuation was done in 336 (24%) patients, by craniotomy in 245 (73%) of those patients and by decompressive craniectomy in 91 (27%). Delayed decompressive craniectomy or craniotomy after initial conservative treatment (n=982) occurred in 107 (11%) patients. The percentage of patients who underwent acute surgery ranged from 5·6% to 51·5% (IQR 12·3-35·9) between centres, with a two-times higher probability of receiving acute surgery for an identical patient in one centre versus another centre at random (adjusted MOR for acute surgery 1·8; p<0·0001]). Centre preference for acute surgery over initial conservative treatment was not associated with improvements in functional outcome (common OR per 23·6% [IQR increase] more acute surgery in a centre 0·92, 95% CI 0·77-1·09). - Interpretation - Our findings show that treatment for patients with acute subdural haematoma with similar characteristics differed depending on the treating centre, because of variation in the preferred approach. A treatment strategy preferring an aggressive approach of acute surgical evacuation over initial conservative treatment was not associated with better functional outcome. Therefore, in a patient with acute subdural haematoma for whom a neurosurgeon sees no clear superiority for acute surgery over conservative treatment, initial conservative treatment might be considered. - Funding - The Hersenstichting Nederland (also known as the Dutch Brain Foundation), the European Commission Seventh Framework Programme, the Hannelore Kohl Stiftung (Germany), OneMind (USA), Integra LifeSciences Corporation (USA), and NeuroTrauma Sciences (USA). Lingsma, Hester F verfasserin aut Pisică, Dana verfasserin aut Singh, Ranjit D verfasserin aut Volovici, Victor verfasserin aut den Boogert, Hugo F verfasserin aut Younsi, Alexander 1985- verfasserin (DE-588)104607508X (DE-627)775681547 (DE-576)39935882X aut Peppel, Lianne D verfasserin aut Heijenbrok-Kal, Majanka H verfasserin aut Ribbers, Gerard M verfasserin aut Walchenbach, Robert verfasserin aut Menon, David K verfasserin aut Hutchinson, Peter verfasserin aut Depreitere, Bart verfasserin aut Steyerberg, Ewout W verfasserin aut Maas, Andrew I R verfasserin aut de Ruiter, Godard C W verfasserin aut Peul, Wilco C verfasserin aut Åkerlund, Cecilia verfasserin aut Amrein, Krisztina verfasserin aut Andelic, Nada verfasserin aut Andreassen, Lasse verfasserin aut Anke, Audny verfasserin aut Antoni, Anna verfasserin aut Audibert, Gérard verfasserin aut Azouvi, Philippe verfasserin aut Azzolini, Maria Luisa verfasserin aut Bartels, Ronald verfasserin aut Barzó, Pál verfasserin aut Beauvais, Romuald verfasserin aut Beer, Ronny verfasserin aut Bellander, Bo-Michael verfasserin aut Belli, Antonio verfasserin aut Benali, Habib verfasserin aut Berardino, Maurizio verfasserin aut Beretta, Luigi verfasserin aut Blaabjerg, Morten verfasserin aut Bragge, Peter verfasserin aut Brazinova, Alexandra verfasserin aut Brinck, Vibeke verfasserin aut Brooker, Joanne verfasserin aut Brorsson, Camilla verfasserin aut Buki, Andras verfasserin aut Bullinger, Monika verfasserin aut Cabeleira, Manuel verfasserin aut Caccioppola, Alessio verfasserin aut Calappi, Emiliana verfasserin aut Calvi, Maria Rosa verfasserin aut Cameron, Peter verfasserin aut Carbayo Lozano, Guillermo verfasserin aut Carbonara, Marco verfasserin aut Castaño-León, Ana M. verfasserin aut Cavallo, Simona verfasserin aut Chevallard, Giorgio verfasserin aut Chieregato, Arturo verfasserin aut Citerio, Giuseppe verfasserin aut Clusmann, Hans verfasserin aut Coburn, Mark Steven verfasserin aut Coles, Jonathan verfasserin aut Cooper, Jamie D. verfasserin aut Correia, Marta verfasserin aut Čović, Amra verfasserin aut Curry, Nicola verfasserin aut Czeiter, Endre verfasserin aut Czosnyka, Marek verfasserin aut Dahyot-Fizelier, Claire verfasserin aut Dark, Paul verfasserin aut Dawes, Helen verfasserin aut De Keyser, Véronique verfasserin aut Degos, Vincent verfasserin aut Della Corte, Francesco verfasserin aut Đilvesi, Đula verfasserin aut Dixit, Abhishek verfasserin aut Donoghue, Emma verfasserin aut Dreier, Jens verfasserin aut Dulière, Guy-Loup verfasserin aut Ercole, Ari verfasserin aut Esser, Patrick verfasserin aut Ezer, Erzsébet verfasserin aut Fabricius, Martin verfasserin aut Feigin, Valery L. verfasserin aut Foks, Kelly verfasserin aut Frisvold, Shirin verfasserin aut Furmanov, Alex verfasserin aut Gagliardo, Pablo verfasserin aut Galanaud, Damien verfasserin aut Gantner, Dashiell verfasserin aut Gao, Guoyi verfasserin aut George, Pradeep verfasserin aut Ghuysen, Alexandre verfasserin aut Giga, Lelde verfasserin aut Glocker, Ben verfasserin aut Golubović, Jagoš verfasserin aut Gomez, Pedro A. verfasserin aut Gratz, Johannes verfasserin aut Gravesteijn, Benjamin verfasserin aut Grossi, Francesca verfasserin aut Gruen, Russell L. verfasserin aut Gupta, Deepak verfasserin aut Haagsma, Juanita A. verfasserin aut Haitsma, Iain verfasserin aut Helbok, Raimund verfasserin aut Helseth, Eirik verfasserin aut Horton, Lindsay verfasserin aut Huijben, Jilske verfasserin aut Jacobs, Bram verfasserin aut Jankowski, Stefan verfasserin aut Jarrett, Mike verfasserin aut Jiang, Ji-yao verfasserin aut Johnson, Faye verfasserin aut Jones, Kelly verfasserin aut Karan, Mladen verfasserin aut Kolias, Angelos G. verfasserin aut Kompanje, Erwin verfasserin aut Kondziella, Daniel verfasserin aut Kornaropoulos, Evgenios verfasserin aut Koskinen, Lars-Owe verfasserin aut Kovács, Noémi verfasserin aut Lagares, Alfonso verfasserin aut Lanyon, Linda verfasserin aut Laureys, Steven verfasserin aut Lecky, Fiona verfasserin aut Ledoux, Didier verfasserin aut Lefering, Rolf verfasserin aut Legrand, Valerie verfasserin aut Lejeune, Aurelie verfasserin aut Levi, Leon verfasserin aut Lightfoot, Roger verfasserin aut Maegele, Marc verfasserin aut Majdan, Marek verfasserin aut Manara, Alex verfasserin aut Manley, Geoffrey verfasserin aut Maréchal, Hugues verfasserin aut Martino, Costanza verfasserin aut Mattern, Julia verfasserin aut McMahon, Catherine verfasserin aut Melegh, Béla verfasserin aut Menovsky, Tomas verfasserin aut Mikolic, Ana verfasserin aut Misset, Benoit verfasserin aut Muraleedharan, Visakh verfasserin aut Murray, Lynnette verfasserin aut Nair, Nandesh verfasserin aut Negru, Ancuta verfasserin aut Nelson, David verfasserin aut Newcombe, Virginia verfasserin aut Nieboer, Daan verfasserin aut Nyirádi, József verfasserin aut Oresic, Matej verfasserin aut Ortolano, Fabrizio verfasserin aut Otesile, Olubukola verfasserin aut Palotie, Aarno verfasserin aut Parizel, Paul M. verfasserin aut Payen, Jean-François verfasserin aut Perera, Natascha verfasserin aut Perlbarg, Vincent verfasserin aut Persona, Paolo verfasserin aut Piippo-Karjalainen, Anna verfasserin aut Pirinen, Matti verfasserin aut Ples, Horia verfasserin aut Polinder, Suzanne verfasserin aut Pomposo, Inigo verfasserin aut Posti, Jussi P. verfasserin aut Puybasset, Louis verfasserin aut Rădoi, Andreea verfasserin aut Ragauskas, Arminas verfasserin aut Raj, Rahul verfasserin aut Rambadagalla, Malinka verfasserin aut Rehorčíková, Veronika verfasserin aut Retel Helmrich, Isabel verfasserin aut Rhodes, Jonathan verfasserin aut Richardson, Sylvia verfasserin aut Richter, Sophie verfasserin aut Ripatti, Samuli verfasserin aut Rocka, Saulius verfasserin aut Roe, Cecilie verfasserin aut Roise, Olav verfasserin aut Rosand, Jonathan verfasserin aut Rosenfeld, Jeffrey verfasserin aut Rosenlund, Christina verfasserin aut Rosenthal, Guy verfasserin aut Rossaint, Rolf verfasserin aut Rossi, Sandra verfasserin aut Rueckert, Daniel verfasserin aut Rusnák, Martin verfasserin aut Sahuquillo, Juan verfasserin aut Sakowitz, Oliver verfasserin aut Sanchez-Porras, Renan verfasserin aut Sandor, Janos verfasserin aut Schäfer, Nadine verfasserin aut Schmidt, Silke verfasserin aut Schoechl, Herbert verfasserin aut Schoonman, Guus verfasserin aut Schou, Rico Frederik verfasserin aut Schwendenwein, Elisabeth verfasserin aut Sewalt, Charlie verfasserin aut Skandsen, Toril verfasserin aut Smielewski, Peter verfasserin aut Sorinola, Abayomi verfasserin aut Stamatakis, Emmanuel verfasserin aut Stanworth, Simon verfasserin aut Kowark, Ana verfasserin aut Stevens, Robert verfasserin aut Stewart, William verfasserin aut Stocchetti, Nino verfasserin aut Sundström, Nina verfasserin aut Takala, Riikka verfasserin aut Tamás, Viktória verfasserin aut Tamosuitis, Tomas verfasserin aut Taylor, Mark Steven verfasserin aut Te Ao, Braden verfasserin aut Tenovuo, Olli verfasserin aut Theadom, Alice verfasserin aut Thomas, Matt verfasserin aut Tibboel, Dick verfasserin aut Timmers, Marjolijn verfasserin aut Tolias, Christos verfasserin aut Trapani, Tony verfasserin aut Tudora, Cristina Maria verfasserin aut Unterberg, Andreas verfasserin aut Vajkoczy, Peter verfasserin aut Valeinis, Egils verfasserin aut Vallance, Shirley verfasserin aut Vámos, Zoltán verfasserin aut Van der Jagt, Mathieu verfasserin aut van der Naalt, Joukje verfasserin aut Van der Steen, Gregory verfasserin aut van Dijck, Jeroen T. J. M. verfasserin aut Van Hecke, Wim verfasserin aut van Heugten, Caroline verfasserin aut Van Praag, Dominique verfasserin aut Van Veen, Ernest verfasserin aut van Wijk, Roel verfasserin aut Vande Vyvere, Thijs verfasserin aut Vargiolu, Alessia verfasserin aut Vega, Emmanuel verfasserin aut Velt, Kimberley verfasserin aut Verheyden, Jan verfasserin aut Vespa, Paul M. verfasserin aut Vik, Anne verfasserin aut Vilcinis, Rimantas verfasserin aut von Steinbüchel, Nicole verfasserin aut Voormolen, Daphne verfasserin aut Vulekovic, Petar verfasserin aut Wang, Kevin K. W. verfasserin aut Wiegers, Eveline verfasserin aut Williams, Guy verfasserin aut Wilson, Lindsay verfasserin aut Winzeck, Stefan verfasserin aut Wolf, Stefan verfasserin aut Yang, Zhihui verfasserin aut Ylén, Peter verfasserin aut Zeiler, Frederick A. verfasserin aut Ziverte, Agate verfasserin aut Zoerle, Tommaso verfasserin aut Enthalten in The lancet London : Lancet Publ. Group, 2002 21(2022), 7 vom: Juli, Seite 620-631 Online-Ressource (DE-627)348587104 (DE-600)2079704-7 (DE-576)110736362 1474-4465 nnns volume:21 year:2022 number:7 month:07 pages:620-631 extent:12 https://doi.org/10.1016/S1474-4422(22)00166-1 Verlag Resolving-System lizenzpflichtig Volltext https://www.sciencedirect.com/science/article/pii/S1474442222001661 Verlag lizenzpflichtig Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 21 2022 7 7 620-631 12 2013 01 DE-16-250 4191345133 00 --%%-- --%%-- --%%-- --%%-- l01 25-09-22 2013 01 DE-16-250 00 s hd2022 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_255 2013 01 DE-16-250 03 s s_12 2013 01 DE-16-250 04 p (DE-627)1493914448 Younsi, Alexander 2013 01 DE-16-250 04 k (DE-627)141674133X Neurochirurgische Universitätsklinik 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_7 |
| allfields_unstemmed |
10.1016/S1474-4422(22)00166-1 doi (DE-627)1817370863 (DE-599)KXP1817370863 (OCoLC)1361696287 DE-627 ger DE-627 rda eng Essen, Thomas van verfasserin (DE-588)1190840006 (DE-627)1669416119 aut Surgery versus conservative treatment for traumatic acute subdural haematoma a prospective, multicentre, observational, comparative effectiveness study Thomas A van Essen, Hester F Lingsma, Dana Pisică, Ranjit D Singh, Victor Volovici, Hugo F den Boogert, Alexander Younsi, Lianne D Peppel, Majanka H Heijenbrok-Kal, Gerard M Ribbers, Robert Walchenbach, David K Menon, Peter Hutchinson, Bart Depreitere, Ewout W Steyerberg, Andrew I R Maas, Godard C W de Ruiter, Wilco C Peul, on behalf of the CENTER-TBI Collaboration Group May 5, 2022 12 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Gesehen am 25.09.2022 CENTER-TBI Collaboration Group: Cecilia Åkerlund, Krisztina Amrein, Nada Andelic, Lasse Andreassen, Audny Anke, Anna Antoni, Gérard Audibert, Philippe Azouvi, Maria Luisa Azzolini, Ronald Bartels, Pál Barzó [und viele weitere] Background - Despite being well established, acute surgery in traumatic acute subdural haematoma is based on low-grade evidence. We aimed to compare the effectiveness of a strategy preferring acute surgical evacuation with one preferring initial conservative treatment in acute subdural haematoma. - Methods - We did a prospective, observational, comparative effectiveness study using data from participants enrolled in the Collaborative European Neurotrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) cohort. We included patients with no pre-existing severe neurological disorders who presented with acute subdural haematoma within 24 h of traumatic brain injury. Using an instrumental variable analysis, we compared outcomes between centres according to treatment preference for acute subdural haematoma (acute surgical evacuation or initial conservative treatment), measured by the case-mix-adjusted percentage of acute surgery per centre. The primary endpoint was functional outcome at 6 months as rated with the Glasgow Outcome Scale Extended, which was estimated with ordinal regression as a common odds ratio (OR) and adjusted for prespecified confounders. Variation in centre preference was quantified with the median OR (MOR). CENTER-TBI is registered with ClinicalTrials.gov, number NCT02210221, and the Resource Identification Portal (Research Resource Identifier SCR_015582). - Findings - Between Dec 19, 2014 and Dec 17, 2017, 4559 patients with traumatic brain injury were enrolled in CENTER-TBI, of whom 1407 (31%) presented with acute subdural haematoma and were included in our study. Acute surgical evacuation was done in 336 (24%) patients, by craniotomy in 245 (73%) of those patients and by decompressive craniectomy in 91 (27%). Delayed decompressive craniectomy or craniotomy after initial conservative treatment (n=982) occurred in 107 (11%) patients. The percentage of patients who underwent acute surgery ranged from 5·6% to 51·5% (IQR 12·3-35·9) between centres, with a two-times higher probability of receiving acute surgery for an identical patient in one centre versus another centre at random (adjusted MOR for acute surgery 1·8; p<0·0001]). Centre preference for acute surgery over initial conservative treatment was not associated with improvements in functional outcome (common OR per 23·6% [IQR increase] more acute surgery in a centre 0·92, 95% CI 0·77-1·09). - Interpretation - Our findings show that treatment for patients with acute subdural haematoma with similar characteristics differed depending on the treating centre, because of variation in the preferred approach. A treatment strategy preferring an aggressive approach of acute surgical evacuation over initial conservative treatment was not associated with better functional outcome. Therefore, in a patient with acute subdural haematoma for whom a neurosurgeon sees no clear superiority for acute surgery over conservative treatment, initial conservative treatment might be considered. - Funding - The Hersenstichting Nederland (also known as the Dutch Brain Foundation), the European Commission Seventh Framework Programme, the Hannelore Kohl Stiftung (Germany), OneMind (USA), Integra LifeSciences Corporation (USA), and NeuroTrauma Sciences (USA). Lingsma, Hester F verfasserin aut Pisică, Dana verfasserin aut Singh, Ranjit D verfasserin aut Volovici, Victor verfasserin aut den Boogert, Hugo F verfasserin aut Younsi, Alexander 1985- verfasserin (DE-588)104607508X (DE-627)775681547 (DE-576)39935882X aut Peppel, Lianne D verfasserin aut Heijenbrok-Kal, Majanka H verfasserin aut Ribbers, Gerard M verfasserin aut Walchenbach, Robert verfasserin aut Menon, David K verfasserin aut Hutchinson, Peter verfasserin aut Depreitere, Bart verfasserin aut Steyerberg, Ewout W verfasserin aut Maas, Andrew I R verfasserin aut de Ruiter, Godard C W verfasserin aut Peul, Wilco C verfasserin aut Åkerlund, Cecilia verfasserin aut Amrein, Krisztina verfasserin aut Andelic, Nada verfasserin aut Andreassen, Lasse verfasserin aut Anke, Audny verfasserin aut Antoni, Anna verfasserin aut Audibert, Gérard verfasserin aut Azouvi, Philippe verfasserin aut Azzolini, Maria Luisa verfasserin aut Bartels, Ronald verfasserin aut Barzó, Pál verfasserin aut Beauvais, Romuald verfasserin aut Beer, Ronny verfasserin aut Bellander, Bo-Michael verfasserin aut Belli, Antonio verfasserin aut Benali, Habib verfasserin aut Berardino, Maurizio verfasserin aut Beretta, Luigi verfasserin aut Blaabjerg, Morten verfasserin aut Bragge, Peter verfasserin aut Brazinova, Alexandra verfasserin aut Brinck, Vibeke verfasserin aut Brooker, Joanne verfasserin aut Brorsson, Camilla verfasserin aut Buki, Andras verfasserin aut Bullinger, Monika verfasserin aut Cabeleira, Manuel verfasserin aut Caccioppola, Alessio verfasserin aut Calappi, Emiliana verfasserin aut Calvi, Maria Rosa verfasserin aut Cameron, Peter verfasserin aut Carbayo Lozano, Guillermo verfasserin aut Carbonara, Marco verfasserin aut Castaño-León, Ana M. verfasserin aut Cavallo, Simona verfasserin aut Chevallard, Giorgio verfasserin aut Chieregato, Arturo verfasserin aut Citerio, Giuseppe verfasserin aut Clusmann, Hans verfasserin aut Coburn, Mark Steven verfasserin aut Coles, Jonathan verfasserin aut Cooper, Jamie D. verfasserin aut Correia, Marta verfasserin aut Čović, Amra verfasserin aut Curry, Nicola verfasserin aut Czeiter, Endre verfasserin aut Czosnyka, Marek verfasserin aut Dahyot-Fizelier, Claire verfasserin aut Dark, Paul verfasserin aut Dawes, Helen verfasserin aut De Keyser, Véronique verfasserin aut Degos, Vincent verfasserin aut Della Corte, Francesco verfasserin aut Đilvesi, Đula verfasserin aut Dixit, Abhishek verfasserin aut Donoghue, Emma verfasserin aut Dreier, Jens verfasserin aut Dulière, Guy-Loup verfasserin aut Ercole, Ari verfasserin aut Esser, Patrick verfasserin aut Ezer, Erzsébet verfasserin aut Fabricius, Martin verfasserin aut Feigin, Valery L. verfasserin aut Foks, Kelly verfasserin aut Frisvold, Shirin verfasserin aut Furmanov, Alex verfasserin aut Gagliardo, Pablo verfasserin aut Galanaud, Damien verfasserin aut Gantner, Dashiell verfasserin aut Gao, Guoyi verfasserin aut George, Pradeep verfasserin aut Ghuysen, Alexandre verfasserin aut Giga, Lelde verfasserin aut Glocker, Ben verfasserin aut Golubović, Jagoš verfasserin aut Gomez, Pedro A. verfasserin aut Gratz, Johannes verfasserin aut Gravesteijn, Benjamin verfasserin aut Grossi, Francesca verfasserin aut Gruen, Russell L. verfasserin aut Gupta, Deepak verfasserin aut Haagsma, Juanita A. verfasserin aut Haitsma, Iain verfasserin aut Helbok, Raimund verfasserin aut Helseth, Eirik verfasserin aut Horton, Lindsay verfasserin aut Huijben, Jilske verfasserin aut Jacobs, Bram verfasserin aut Jankowski, Stefan verfasserin aut Jarrett, Mike verfasserin aut Jiang, Ji-yao verfasserin aut Johnson, Faye verfasserin aut Jones, Kelly verfasserin aut Karan, Mladen verfasserin aut Kolias, Angelos G. verfasserin aut Kompanje, Erwin verfasserin aut Kondziella, Daniel verfasserin aut Kornaropoulos, Evgenios verfasserin aut Koskinen, Lars-Owe verfasserin aut Kovács, Noémi verfasserin aut Lagares, Alfonso verfasserin aut Lanyon, Linda verfasserin aut Laureys, Steven verfasserin aut Lecky, Fiona verfasserin aut Ledoux, Didier verfasserin aut Lefering, Rolf verfasserin aut Legrand, Valerie verfasserin aut Lejeune, Aurelie verfasserin aut Levi, Leon verfasserin aut Lightfoot, Roger verfasserin aut Maegele, Marc verfasserin aut Majdan, Marek verfasserin aut Manara, Alex verfasserin aut Manley, Geoffrey verfasserin aut Maréchal, Hugues verfasserin aut Martino, Costanza verfasserin aut Mattern, Julia verfasserin aut McMahon, Catherine verfasserin aut Melegh, Béla verfasserin aut Menovsky, Tomas verfasserin aut Mikolic, Ana verfasserin aut Misset, Benoit verfasserin aut Muraleedharan, Visakh verfasserin aut Murray, Lynnette verfasserin aut Nair, Nandesh verfasserin aut Negru, Ancuta verfasserin aut Nelson, David verfasserin aut Newcombe, Virginia verfasserin aut Nieboer, Daan verfasserin aut Nyirádi, József verfasserin aut Oresic, Matej verfasserin aut Ortolano, Fabrizio verfasserin aut Otesile, Olubukola verfasserin aut Palotie, Aarno verfasserin aut Parizel, Paul M. verfasserin aut Payen, Jean-François verfasserin aut Perera, Natascha verfasserin aut Perlbarg, Vincent verfasserin aut Persona, Paolo verfasserin aut Piippo-Karjalainen, Anna verfasserin aut Pirinen, Matti verfasserin aut Ples, Horia verfasserin aut Polinder, Suzanne verfasserin aut Pomposo, Inigo verfasserin aut Posti, Jussi P. verfasserin aut Puybasset, Louis verfasserin aut Rădoi, Andreea verfasserin aut Ragauskas, Arminas verfasserin aut Raj, Rahul verfasserin aut Rambadagalla, Malinka verfasserin aut Rehorčíková, Veronika verfasserin aut Retel Helmrich, Isabel verfasserin aut Rhodes, Jonathan verfasserin aut Richardson, Sylvia verfasserin aut Richter, Sophie verfasserin aut Ripatti, Samuli verfasserin aut Rocka, Saulius verfasserin aut Roe, Cecilie verfasserin aut Roise, Olav verfasserin aut Rosand, Jonathan verfasserin aut Rosenfeld, Jeffrey verfasserin aut Rosenlund, Christina verfasserin aut Rosenthal, Guy verfasserin aut Rossaint, Rolf verfasserin aut Rossi, Sandra verfasserin aut Rueckert, Daniel verfasserin aut Rusnák, Martin verfasserin aut Sahuquillo, Juan verfasserin aut Sakowitz, Oliver verfasserin aut Sanchez-Porras, Renan verfasserin aut Sandor, Janos verfasserin aut Schäfer, Nadine verfasserin aut Schmidt, Silke verfasserin aut Schoechl, Herbert verfasserin aut Schoonman, Guus verfasserin aut Schou, Rico Frederik verfasserin aut Schwendenwein, Elisabeth verfasserin aut Sewalt, Charlie verfasserin aut Skandsen, Toril verfasserin aut Smielewski, Peter verfasserin aut Sorinola, Abayomi verfasserin aut Stamatakis, Emmanuel verfasserin aut Stanworth, Simon verfasserin aut Kowark, Ana verfasserin aut Stevens, Robert verfasserin aut Stewart, William verfasserin aut Stocchetti, Nino verfasserin aut Sundström, Nina verfasserin aut Takala, Riikka verfasserin aut Tamás, Viktória verfasserin aut Tamosuitis, Tomas verfasserin aut Taylor, Mark Steven verfasserin aut Te Ao, Braden verfasserin aut Tenovuo, Olli verfasserin aut Theadom, Alice verfasserin aut Thomas, Matt verfasserin aut Tibboel, Dick verfasserin aut Timmers, Marjolijn verfasserin aut Tolias, Christos verfasserin aut Trapani, Tony verfasserin aut Tudora, Cristina Maria verfasserin aut Unterberg, Andreas verfasserin aut Vajkoczy, Peter verfasserin aut Valeinis, Egils verfasserin aut Vallance, Shirley verfasserin aut Vámos, Zoltán verfasserin aut Van der Jagt, Mathieu verfasserin aut van der Naalt, Joukje verfasserin aut Van der Steen, Gregory verfasserin aut van Dijck, Jeroen T. J. M. verfasserin aut Van Hecke, Wim verfasserin aut van Heugten, Caroline verfasserin aut Van Praag, Dominique verfasserin aut Van Veen, Ernest verfasserin aut van Wijk, Roel verfasserin aut Vande Vyvere, Thijs verfasserin aut Vargiolu, Alessia verfasserin aut Vega, Emmanuel verfasserin aut Velt, Kimberley verfasserin aut Verheyden, Jan verfasserin aut Vespa, Paul M. verfasserin aut Vik, Anne verfasserin aut Vilcinis, Rimantas verfasserin aut von Steinbüchel, Nicole verfasserin aut Voormolen, Daphne verfasserin aut Vulekovic, Petar verfasserin aut Wang, Kevin K. W. verfasserin aut Wiegers, Eveline verfasserin aut Williams, Guy verfasserin aut Wilson, Lindsay verfasserin aut Winzeck, Stefan verfasserin aut Wolf, Stefan verfasserin aut Yang, Zhihui verfasserin aut Ylén, Peter verfasserin aut Zeiler, Frederick A. verfasserin aut Ziverte, Agate verfasserin aut Zoerle, Tommaso verfasserin aut Enthalten in The lancet London : Lancet Publ. Group, 2002 21(2022), 7 vom: Juli, Seite 620-631 Online-Ressource (DE-627)348587104 (DE-600)2079704-7 (DE-576)110736362 1474-4465 nnns volume:21 year:2022 number:7 month:07 pages:620-631 extent:12 https://doi.org/10.1016/S1474-4422(22)00166-1 Verlag Resolving-System lizenzpflichtig Volltext https://www.sciencedirect.com/science/article/pii/S1474442222001661 Verlag lizenzpflichtig Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 21 2022 7 7 620-631 12 2013 01 DE-16-250 4191345133 00 --%%-- --%%-- --%%-- --%%-- l01 25-09-22 2013 01 DE-16-250 00 s hd2022 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_255 2013 01 DE-16-250 03 s s_12 2013 01 DE-16-250 04 p (DE-627)1493914448 Younsi, Alexander 2013 01 DE-16-250 04 k (DE-627)141674133X Neurochirurgische Universitätsklinik 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_7 |
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10.1016/S1474-4422(22)00166-1 doi (DE-627)1817370863 (DE-599)KXP1817370863 (OCoLC)1361696287 DE-627 ger DE-627 rda eng Essen, Thomas van verfasserin (DE-588)1190840006 (DE-627)1669416119 aut Surgery versus conservative treatment for traumatic acute subdural haematoma a prospective, multicentre, observational, comparative effectiveness study Thomas A van Essen, Hester F Lingsma, Dana Pisică, Ranjit D Singh, Victor Volovici, Hugo F den Boogert, Alexander Younsi, Lianne D Peppel, Majanka H Heijenbrok-Kal, Gerard M Ribbers, Robert Walchenbach, David K Menon, Peter Hutchinson, Bart Depreitere, Ewout W Steyerberg, Andrew I R Maas, Godard C W de Ruiter, Wilco C Peul, on behalf of the CENTER-TBI Collaboration Group May 5, 2022 12 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Gesehen am 25.09.2022 CENTER-TBI Collaboration Group: Cecilia Åkerlund, Krisztina Amrein, Nada Andelic, Lasse Andreassen, Audny Anke, Anna Antoni, Gérard Audibert, Philippe Azouvi, Maria Luisa Azzolini, Ronald Bartels, Pál Barzó [und viele weitere] Background - Despite being well established, acute surgery in traumatic acute subdural haematoma is based on low-grade evidence. We aimed to compare the effectiveness of a strategy preferring acute surgical evacuation with one preferring initial conservative treatment in acute subdural haematoma. - Methods - We did a prospective, observational, comparative effectiveness study using data from participants enrolled in the Collaborative European Neurotrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) cohort. We included patients with no pre-existing severe neurological disorders who presented with acute subdural haematoma within 24 h of traumatic brain injury. Using an instrumental variable analysis, we compared outcomes between centres according to treatment preference for acute subdural haematoma (acute surgical evacuation or initial conservative treatment), measured by the case-mix-adjusted percentage of acute surgery per centre. The primary endpoint was functional outcome at 6 months as rated with the Glasgow Outcome Scale Extended, which was estimated with ordinal regression as a common odds ratio (OR) and adjusted for prespecified confounders. Variation in centre preference was quantified with the median OR (MOR). CENTER-TBI is registered with ClinicalTrials.gov, number NCT02210221, and the Resource Identification Portal (Research Resource Identifier SCR_015582). - Findings - Between Dec 19, 2014 and Dec 17, 2017, 4559 patients with traumatic brain injury were enrolled in CENTER-TBI, of whom 1407 (31%) presented with acute subdural haematoma and were included in our study. Acute surgical evacuation was done in 336 (24%) patients, by craniotomy in 245 (73%) of those patients and by decompressive craniectomy in 91 (27%). Delayed decompressive craniectomy or craniotomy after initial conservative treatment (n=982) occurred in 107 (11%) patients. The percentage of patients who underwent acute surgery ranged from 5·6% to 51·5% (IQR 12·3-35·9) between centres, with a two-times higher probability of receiving acute surgery for an identical patient in one centre versus another centre at random (adjusted MOR for acute surgery 1·8; p<0·0001]). Centre preference for acute surgery over initial conservative treatment was not associated with improvements in functional outcome (common OR per 23·6% [IQR increase] more acute surgery in a centre 0·92, 95% CI 0·77-1·09). - Interpretation - Our findings show that treatment for patients with acute subdural haematoma with similar characteristics differed depending on the treating centre, because of variation in the preferred approach. A treatment strategy preferring an aggressive approach of acute surgical evacuation over initial conservative treatment was not associated with better functional outcome. Therefore, in a patient with acute subdural haematoma for whom a neurosurgeon sees no clear superiority for acute surgery over conservative treatment, initial conservative treatment might be considered. - Funding - The Hersenstichting Nederland (also known as the Dutch Brain Foundation), the European Commission Seventh Framework Programme, the Hannelore Kohl Stiftung (Germany), OneMind (USA), Integra LifeSciences Corporation (USA), and NeuroTrauma Sciences (USA). Lingsma, Hester F verfasserin aut Pisică, Dana verfasserin aut Singh, Ranjit D verfasserin aut Volovici, Victor verfasserin aut den Boogert, Hugo F verfasserin aut Younsi, Alexander 1985- verfasserin (DE-588)104607508X (DE-627)775681547 (DE-576)39935882X aut Peppel, Lianne D verfasserin aut Heijenbrok-Kal, Majanka H verfasserin aut Ribbers, Gerard M verfasserin aut Walchenbach, Robert verfasserin aut Menon, David K verfasserin aut Hutchinson, Peter verfasserin aut Depreitere, Bart verfasserin aut Steyerberg, Ewout W verfasserin aut Maas, Andrew I R verfasserin aut de Ruiter, Godard C W verfasserin aut Peul, Wilco C verfasserin aut Åkerlund, Cecilia verfasserin aut Amrein, Krisztina verfasserin aut Andelic, Nada verfasserin aut Andreassen, Lasse verfasserin aut Anke, Audny verfasserin aut Antoni, Anna verfasserin aut Audibert, Gérard verfasserin aut Azouvi, Philippe verfasserin aut Azzolini, Maria Luisa verfasserin aut Bartels, Ronald verfasserin aut Barzó, Pál verfasserin aut Beauvais, Romuald verfasserin aut Beer, Ronny verfasserin aut Bellander, Bo-Michael verfasserin aut Belli, Antonio verfasserin aut Benali, Habib verfasserin aut Berardino, Maurizio verfasserin aut Beretta, Luigi verfasserin aut Blaabjerg, Morten verfasserin aut Bragge, Peter verfasserin aut Brazinova, Alexandra verfasserin aut Brinck, Vibeke verfasserin aut Brooker, Joanne verfasserin aut Brorsson, Camilla verfasserin aut Buki, Andras verfasserin aut Bullinger, Monika verfasserin aut Cabeleira, Manuel verfasserin aut Caccioppola, Alessio verfasserin aut Calappi, Emiliana verfasserin aut Calvi, Maria Rosa verfasserin aut Cameron, Peter verfasserin aut Carbayo Lozano, Guillermo verfasserin aut Carbonara, Marco verfasserin aut Castaño-León, Ana M. verfasserin aut Cavallo, Simona verfasserin aut Chevallard, Giorgio verfasserin aut Chieregato, Arturo verfasserin aut Citerio, Giuseppe verfasserin aut Clusmann, Hans verfasserin aut Coburn, Mark Steven verfasserin aut Coles, Jonathan verfasserin aut Cooper, Jamie D. verfasserin aut Correia, Marta verfasserin aut Čović, Amra verfasserin aut Curry, Nicola verfasserin aut Czeiter, Endre verfasserin aut Czosnyka, Marek verfasserin aut Dahyot-Fizelier, Claire verfasserin aut Dark, Paul verfasserin aut Dawes, Helen verfasserin aut De Keyser, Véronique verfasserin aut Degos, Vincent verfasserin aut Della Corte, Francesco verfasserin aut Đilvesi, Đula verfasserin aut Dixit, Abhishek verfasserin aut Donoghue, Emma verfasserin aut Dreier, Jens verfasserin aut Dulière, Guy-Loup verfasserin aut Ercole, Ari verfasserin aut Esser, Patrick verfasserin aut Ezer, Erzsébet verfasserin aut Fabricius, Martin verfasserin aut Feigin, Valery L. verfasserin aut Foks, Kelly verfasserin aut Frisvold, Shirin verfasserin aut Furmanov, Alex verfasserin aut Gagliardo, Pablo verfasserin aut Galanaud, Damien verfasserin aut Gantner, Dashiell verfasserin aut Gao, Guoyi verfasserin aut George, Pradeep verfasserin aut Ghuysen, Alexandre verfasserin aut Giga, Lelde verfasserin aut Glocker, Ben verfasserin aut Golubović, Jagoš verfasserin aut Gomez, Pedro A. verfasserin aut Gratz, Johannes verfasserin aut Gravesteijn, Benjamin verfasserin aut Grossi, Francesca verfasserin aut Gruen, Russell L. verfasserin aut Gupta, Deepak verfasserin aut Haagsma, Juanita A. verfasserin aut Haitsma, Iain verfasserin aut Helbok, Raimund verfasserin aut Helseth, Eirik verfasserin aut Horton, Lindsay verfasserin aut Huijben, Jilske verfasserin aut Jacobs, Bram verfasserin aut Jankowski, Stefan verfasserin aut Jarrett, Mike verfasserin aut Jiang, Ji-yao verfasserin aut Johnson, Faye verfasserin aut Jones, Kelly verfasserin aut Karan, Mladen verfasserin aut Kolias, Angelos G. verfasserin aut Kompanje, Erwin verfasserin aut Kondziella, Daniel verfasserin aut Kornaropoulos, Evgenios verfasserin aut Koskinen, Lars-Owe verfasserin aut Kovács, Noémi verfasserin aut Lagares, Alfonso verfasserin aut Lanyon, Linda verfasserin aut Laureys, Steven verfasserin aut Lecky, Fiona verfasserin aut Ledoux, Didier verfasserin aut Lefering, Rolf verfasserin aut Legrand, Valerie verfasserin aut Lejeune, Aurelie verfasserin aut Levi, Leon verfasserin aut Lightfoot, Roger verfasserin aut Maegele, Marc verfasserin aut Majdan, Marek verfasserin aut Manara, Alex verfasserin aut Manley, Geoffrey verfasserin aut Maréchal, Hugues verfasserin aut Martino, Costanza verfasserin aut Mattern, Julia verfasserin aut McMahon, Catherine verfasserin aut Melegh, Béla verfasserin aut Menovsky, Tomas verfasserin aut Mikolic, Ana verfasserin aut Misset, Benoit verfasserin aut Muraleedharan, Visakh verfasserin aut Murray, Lynnette verfasserin aut Nair, Nandesh verfasserin aut Negru, Ancuta verfasserin aut Nelson, David verfasserin aut Newcombe, Virginia verfasserin aut Nieboer, Daan verfasserin aut Nyirádi, József verfasserin aut Oresic, Matej verfasserin aut Ortolano, Fabrizio verfasserin aut Otesile, Olubukola verfasserin aut Palotie, Aarno verfasserin aut Parizel, Paul M. verfasserin aut Payen, Jean-François verfasserin aut Perera, Natascha verfasserin aut Perlbarg, Vincent verfasserin aut Persona, Paolo verfasserin aut Piippo-Karjalainen, Anna verfasserin aut Pirinen, Matti verfasserin aut Ples, Horia verfasserin aut Polinder, Suzanne verfasserin aut Pomposo, Inigo verfasserin aut Posti, Jussi P. verfasserin aut Puybasset, Louis verfasserin aut Rădoi, Andreea verfasserin aut Ragauskas, Arminas verfasserin aut Raj, Rahul verfasserin aut Rambadagalla, Malinka verfasserin aut Rehorčíková, Veronika verfasserin aut Retel Helmrich, Isabel verfasserin aut Rhodes, Jonathan verfasserin aut Richardson, Sylvia verfasserin aut Richter, Sophie verfasserin aut Ripatti, Samuli verfasserin aut Rocka, Saulius verfasserin aut Roe, Cecilie verfasserin aut Roise, Olav verfasserin aut Rosand, Jonathan verfasserin aut Rosenfeld, Jeffrey verfasserin aut Rosenlund, Christina verfasserin aut Rosenthal, Guy verfasserin aut Rossaint, Rolf verfasserin aut Rossi, Sandra verfasserin aut Rueckert, Daniel verfasserin aut Rusnák, Martin verfasserin aut Sahuquillo, Juan verfasserin aut Sakowitz, Oliver verfasserin aut Sanchez-Porras, Renan verfasserin aut Sandor, Janos verfasserin aut Schäfer, Nadine verfasserin aut Schmidt, Silke verfasserin aut Schoechl, Herbert verfasserin aut Schoonman, Guus verfasserin aut Schou, Rico Frederik verfasserin aut Schwendenwein, Elisabeth verfasserin aut Sewalt, Charlie verfasserin aut Skandsen, Toril verfasserin aut Smielewski, Peter verfasserin aut Sorinola, Abayomi verfasserin aut Stamatakis, Emmanuel verfasserin aut Stanworth, Simon verfasserin aut Kowark, Ana verfasserin aut Stevens, Robert verfasserin aut Stewart, William verfasserin aut Stocchetti, Nino verfasserin aut Sundström, Nina verfasserin aut Takala, Riikka verfasserin aut Tamás, Viktória verfasserin aut Tamosuitis, Tomas verfasserin aut Taylor, Mark Steven verfasserin aut Te Ao, Braden verfasserin aut Tenovuo, Olli verfasserin aut Theadom, Alice verfasserin aut Thomas, Matt verfasserin aut Tibboel, Dick verfasserin aut Timmers, Marjolijn verfasserin aut Tolias, Christos verfasserin aut Trapani, Tony verfasserin aut Tudora, Cristina Maria verfasserin aut Unterberg, Andreas verfasserin aut Vajkoczy, Peter verfasserin aut Valeinis, Egils verfasserin aut Vallance, Shirley verfasserin aut Vámos, Zoltán verfasserin aut Van der Jagt, Mathieu verfasserin aut van der Naalt, Joukje verfasserin aut Van der Steen, Gregory verfasserin aut van Dijck, Jeroen T. J. M. verfasserin aut Van Hecke, Wim verfasserin aut van Heugten, Caroline verfasserin aut Van Praag, Dominique verfasserin aut Van Veen, Ernest verfasserin aut van Wijk, Roel verfasserin aut Vande Vyvere, Thijs verfasserin aut Vargiolu, Alessia verfasserin aut Vega, Emmanuel verfasserin aut Velt, Kimberley verfasserin aut Verheyden, Jan verfasserin aut Vespa, Paul M. verfasserin aut Vik, Anne verfasserin aut Vilcinis, Rimantas verfasserin aut von Steinbüchel, Nicole verfasserin aut Voormolen, Daphne verfasserin aut Vulekovic, Petar verfasserin aut Wang, Kevin K. W. verfasserin aut Wiegers, Eveline verfasserin aut Williams, Guy verfasserin aut Wilson, Lindsay verfasserin aut Winzeck, Stefan verfasserin aut Wolf, Stefan verfasserin aut Yang, Zhihui verfasserin aut Ylén, Peter verfasserin aut Zeiler, Frederick A. verfasserin aut Ziverte, Agate verfasserin aut Zoerle, Tommaso verfasserin aut Enthalten in The lancet London : Lancet Publ. Group, 2002 21(2022), 7 vom: Juli, Seite 620-631 Online-Ressource (DE-627)348587104 (DE-600)2079704-7 (DE-576)110736362 1474-4465 nnns volume:21 year:2022 number:7 month:07 pages:620-631 extent:12 https://doi.org/10.1016/S1474-4422(22)00166-1 Verlag Resolving-System lizenzpflichtig Volltext https://www.sciencedirect.com/science/article/pii/S1474442222001661 Verlag lizenzpflichtig Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 21 2022 7 7 620-631 12 2013 01 DE-16-250 4191345133 00 --%%-- --%%-- --%%-- --%%-- l01 25-09-22 2013 01 DE-16-250 00 s hd2022 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_255 2013 01 DE-16-250 03 s s_12 2013 01 DE-16-250 04 p (DE-627)1493914448 Younsi, Alexander 2013 01 DE-16-250 04 k (DE-627)141674133X Neurochirurgische Universitätsklinik 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_7 |
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10.1016/S1474-4422(22)00166-1 doi (DE-627)1817370863 (DE-599)KXP1817370863 (OCoLC)1361696287 DE-627 ger DE-627 rda eng Essen, Thomas van verfasserin (DE-588)1190840006 (DE-627)1669416119 aut Surgery versus conservative treatment for traumatic acute subdural haematoma a prospective, multicentre, observational, comparative effectiveness study Thomas A van Essen, Hester F Lingsma, Dana Pisică, Ranjit D Singh, Victor Volovici, Hugo F den Boogert, Alexander Younsi, Lianne D Peppel, Majanka H Heijenbrok-Kal, Gerard M Ribbers, Robert Walchenbach, David K Menon, Peter Hutchinson, Bart Depreitere, Ewout W Steyerberg, Andrew I R Maas, Godard C W de Ruiter, Wilco C Peul, on behalf of the CENTER-TBI Collaboration Group May 5, 2022 12 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Gesehen am 25.09.2022 CENTER-TBI Collaboration Group: Cecilia Åkerlund, Krisztina Amrein, Nada Andelic, Lasse Andreassen, Audny Anke, Anna Antoni, Gérard Audibert, Philippe Azouvi, Maria Luisa Azzolini, Ronald Bartels, Pál Barzó [und viele weitere] Background - Despite being well established, acute surgery in traumatic acute subdural haematoma is based on low-grade evidence. We aimed to compare the effectiveness of a strategy preferring acute surgical evacuation with one preferring initial conservative treatment in acute subdural haematoma. - Methods - We did a prospective, observational, comparative effectiveness study using data from participants enrolled in the Collaborative European Neurotrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) cohort. We included patients with no pre-existing severe neurological disorders who presented with acute subdural haematoma within 24 h of traumatic brain injury. Using an instrumental variable analysis, we compared outcomes between centres according to treatment preference for acute subdural haematoma (acute surgical evacuation or initial conservative treatment), measured by the case-mix-adjusted percentage of acute surgery per centre. The primary endpoint was functional outcome at 6 months as rated with the Glasgow Outcome Scale Extended, which was estimated with ordinal regression as a common odds ratio (OR) and adjusted for prespecified confounders. Variation in centre preference was quantified with the median OR (MOR). CENTER-TBI is registered with ClinicalTrials.gov, number NCT02210221, and the Resource Identification Portal (Research Resource Identifier SCR_015582). - Findings - Between Dec 19, 2014 and Dec 17, 2017, 4559 patients with traumatic brain injury were enrolled in CENTER-TBI, of whom 1407 (31%) presented with acute subdural haematoma and were included in our study. Acute surgical evacuation was done in 336 (24%) patients, by craniotomy in 245 (73%) of those patients and by decompressive craniectomy in 91 (27%). Delayed decompressive craniectomy or craniotomy after initial conservative treatment (n=982) occurred in 107 (11%) patients. The percentage of patients who underwent acute surgery ranged from 5·6% to 51·5% (IQR 12·3-35·9) between centres, with a two-times higher probability of receiving acute surgery for an identical patient in one centre versus another centre at random (adjusted MOR for acute surgery 1·8; p<0·0001]). Centre preference for acute surgery over initial conservative treatment was not associated with improvements in functional outcome (common OR per 23·6% [IQR increase] more acute surgery in a centre 0·92, 95% CI 0·77-1·09). - Interpretation - Our findings show that treatment for patients with acute subdural haematoma with similar characteristics differed depending on the treating centre, because of variation in the preferred approach. A treatment strategy preferring an aggressive approach of acute surgical evacuation over initial conservative treatment was not associated with better functional outcome. Therefore, in a patient with acute subdural haematoma for whom a neurosurgeon sees no clear superiority for acute surgery over conservative treatment, initial conservative treatment might be considered. - Funding - The Hersenstichting Nederland (also known as the Dutch Brain Foundation), the European Commission Seventh Framework Programme, the Hannelore Kohl Stiftung (Germany), OneMind (USA), Integra LifeSciences Corporation (USA), and NeuroTrauma Sciences (USA). Lingsma, Hester F verfasserin aut Pisică, Dana verfasserin aut Singh, Ranjit D verfasserin aut Volovici, Victor verfasserin aut den Boogert, Hugo F verfasserin aut Younsi, Alexander 1985- verfasserin (DE-588)104607508X (DE-627)775681547 (DE-576)39935882X aut Peppel, Lianne D verfasserin aut Heijenbrok-Kal, Majanka H verfasserin aut Ribbers, Gerard M verfasserin aut Walchenbach, Robert verfasserin aut Menon, David K verfasserin aut Hutchinson, Peter verfasserin aut Depreitere, Bart verfasserin aut Steyerberg, Ewout W verfasserin aut Maas, Andrew I R verfasserin aut de Ruiter, Godard C W verfasserin aut Peul, Wilco C verfasserin aut Åkerlund, Cecilia verfasserin aut Amrein, Krisztina verfasserin aut Andelic, Nada verfasserin aut Andreassen, Lasse verfasserin aut Anke, Audny verfasserin aut Antoni, Anna verfasserin aut Audibert, Gérard verfasserin aut Azouvi, Philippe verfasserin aut Azzolini, Maria Luisa verfasserin aut Bartels, Ronald verfasserin aut Barzó, Pál verfasserin aut Beauvais, Romuald verfasserin aut Beer, Ronny verfasserin aut Bellander, Bo-Michael verfasserin aut Belli, Antonio verfasserin aut Benali, Habib verfasserin aut Berardino, Maurizio verfasserin aut Beretta, Luigi verfasserin aut Blaabjerg, Morten verfasserin aut Bragge, Peter verfasserin aut Brazinova, Alexandra verfasserin aut Brinck, Vibeke verfasserin aut Brooker, Joanne verfasserin aut Brorsson, Camilla verfasserin aut Buki, Andras verfasserin aut Bullinger, Monika verfasserin aut Cabeleira, Manuel verfasserin aut Caccioppola, Alessio verfasserin aut Calappi, Emiliana verfasserin aut Calvi, Maria Rosa verfasserin aut Cameron, Peter verfasserin aut Carbayo Lozano, Guillermo verfasserin aut Carbonara, Marco verfasserin aut Castaño-León, Ana M. verfasserin aut Cavallo, Simona verfasserin aut Chevallard, Giorgio verfasserin aut Chieregato, Arturo verfasserin aut Citerio, Giuseppe verfasserin aut Clusmann, Hans verfasserin aut Coburn, Mark Steven verfasserin aut Coles, Jonathan verfasserin aut Cooper, Jamie D. verfasserin aut Correia, Marta verfasserin aut Čović, Amra verfasserin aut Curry, Nicola verfasserin aut Czeiter, Endre verfasserin aut Czosnyka, Marek verfasserin aut Dahyot-Fizelier, Claire verfasserin aut Dark, Paul verfasserin aut Dawes, Helen verfasserin aut De Keyser, Véronique verfasserin aut Degos, Vincent verfasserin aut Della Corte, Francesco verfasserin aut Đilvesi, Đula verfasserin aut Dixit, Abhishek verfasserin aut Donoghue, Emma verfasserin aut Dreier, Jens verfasserin aut Dulière, Guy-Loup verfasserin aut Ercole, Ari verfasserin aut Esser, Patrick verfasserin aut Ezer, Erzsébet verfasserin aut Fabricius, Martin verfasserin aut Feigin, Valery L. verfasserin aut Foks, Kelly verfasserin aut Frisvold, Shirin verfasserin aut Furmanov, Alex verfasserin aut Gagliardo, Pablo verfasserin aut Galanaud, Damien verfasserin aut Gantner, Dashiell verfasserin aut Gao, Guoyi verfasserin aut George, Pradeep verfasserin aut Ghuysen, Alexandre verfasserin aut Giga, Lelde verfasserin aut Glocker, Ben verfasserin aut Golubović, Jagoš verfasserin aut Gomez, Pedro A. verfasserin aut Gratz, Johannes verfasserin aut Gravesteijn, Benjamin verfasserin aut Grossi, Francesca verfasserin aut Gruen, Russell L. verfasserin aut Gupta, Deepak verfasserin aut Haagsma, Juanita A. verfasserin aut Haitsma, Iain verfasserin aut Helbok, Raimund verfasserin aut Helseth, Eirik verfasserin aut Horton, Lindsay verfasserin aut Huijben, Jilske verfasserin aut Jacobs, Bram verfasserin aut Jankowski, Stefan verfasserin aut Jarrett, Mike verfasserin aut Jiang, Ji-yao verfasserin aut Johnson, Faye verfasserin aut Jones, Kelly verfasserin aut Karan, Mladen verfasserin aut Kolias, Angelos G. verfasserin aut Kompanje, Erwin verfasserin aut Kondziella, Daniel verfasserin aut Kornaropoulos, Evgenios verfasserin aut Koskinen, Lars-Owe verfasserin aut Kovács, Noémi verfasserin aut Lagares, Alfonso verfasserin aut Lanyon, Linda verfasserin aut Laureys, Steven verfasserin aut Lecky, Fiona verfasserin aut Ledoux, Didier verfasserin aut Lefering, Rolf verfasserin aut Legrand, Valerie verfasserin aut Lejeune, Aurelie verfasserin aut Levi, Leon verfasserin aut Lightfoot, Roger verfasserin aut Maegele, Marc verfasserin aut Majdan, Marek verfasserin aut Manara, Alex verfasserin aut Manley, Geoffrey verfasserin aut Maréchal, Hugues verfasserin aut Martino, Costanza verfasserin aut Mattern, Julia verfasserin aut McMahon, Catherine verfasserin aut Melegh, Béla verfasserin aut Menovsky, Tomas verfasserin aut Mikolic, Ana verfasserin aut Misset, Benoit verfasserin aut Muraleedharan, Visakh verfasserin aut Murray, Lynnette verfasserin aut Nair, Nandesh verfasserin aut Negru, Ancuta verfasserin aut Nelson, David verfasserin aut Newcombe, Virginia verfasserin aut Nieboer, Daan verfasserin aut Nyirádi, József verfasserin aut Oresic, Matej verfasserin aut Ortolano, Fabrizio verfasserin aut Otesile, Olubukola verfasserin aut Palotie, Aarno verfasserin aut Parizel, Paul M. verfasserin aut Payen, Jean-François verfasserin aut Perera, Natascha verfasserin aut Perlbarg, Vincent verfasserin aut Persona, Paolo verfasserin aut Piippo-Karjalainen, Anna verfasserin aut Pirinen, Matti verfasserin aut Ples, Horia verfasserin aut Polinder, Suzanne verfasserin aut Pomposo, Inigo verfasserin aut Posti, Jussi P. verfasserin aut Puybasset, Louis verfasserin aut Rădoi, Andreea verfasserin aut Ragauskas, Arminas verfasserin aut Raj, Rahul verfasserin aut Rambadagalla, Malinka verfasserin aut Rehorčíková, Veronika verfasserin aut Retel Helmrich, Isabel verfasserin aut Rhodes, Jonathan verfasserin aut Richardson, Sylvia verfasserin aut Richter, Sophie verfasserin aut Ripatti, Samuli verfasserin aut Rocka, Saulius verfasserin aut Roe, Cecilie verfasserin aut Roise, Olav verfasserin aut Rosand, Jonathan verfasserin aut Rosenfeld, Jeffrey verfasserin aut Rosenlund, Christina verfasserin aut Rosenthal, Guy verfasserin aut Rossaint, Rolf verfasserin aut Rossi, Sandra verfasserin aut Rueckert, Daniel verfasserin aut Rusnák, Martin verfasserin aut Sahuquillo, Juan verfasserin aut Sakowitz, Oliver verfasserin aut Sanchez-Porras, Renan verfasserin aut Sandor, Janos verfasserin aut Schäfer, Nadine verfasserin aut Schmidt, Silke verfasserin aut Schoechl, Herbert verfasserin aut Schoonman, Guus verfasserin aut Schou, Rico Frederik verfasserin aut Schwendenwein, Elisabeth verfasserin aut Sewalt, Charlie verfasserin aut Skandsen, Toril verfasserin aut Smielewski, Peter verfasserin aut Sorinola, Abayomi verfasserin aut Stamatakis, Emmanuel verfasserin aut Stanworth, Simon verfasserin aut Kowark, Ana verfasserin aut Stevens, Robert verfasserin aut Stewart, William verfasserin aut Stocchetti, Nino verfasserin aut Sundström, Nina verfasserin aut Takala, Riikka verfasserin aut Tamás, Viktória verfasserin aut Tamosuitis, Tomas verfasserin aut Taylor, Mark Steven verfasserin aut Te Ao, Braden verfasserin aut Tenovuo, Olli verfasserin aut Theadom, Alice verfasserin aut Thomas, Matt verfasserin aut Tibboel, Dick verfasserin aut Timmers, Marjolijn verfasserin aut Tolias, Christos verfasserin aut Trapani, Tony verfasserin aut Tudora, Cristina Maria verfasserin aut Unterberg, Andreas verfasserin aut Vajkoczy, Peter verfasserin aut Valeinis, Egils verfasserin aut Vallance, Shirley verfasserin aut Vámos, Zoltán verfasserin aut Van der Jagt, Mathieu verfasserin aut van der Naalt, Joukje verfasserin aut Van der Steen, Gregory verfasserin aut van Dijck, Jeroen T. J. M. verfasserin aut Van Hecke, Wim verfasserin aut van Heugten, Caroline verfasserin aut Van Praag, Dominique verfasserin aut Van Veen, Ernest verfasserin aut van Wijk, Roel verfasserin aut Vande Vyvere, Thijs verfasserin aut Vargiolu, Alessia verfasserin aut Vega, Emmanuel verfasserin aut Velt, Kimberley verfasserin aut Verheyden, Jan verfasserin aut Vespa, Paul M. verfasserin aut Vik, Anne verfasserin aut Vilcinis, Rimantas verfasserin aut von Steinbüchel, Nicole verfasserin aut Voormolen, Daphne verfasserin aut Vulekovic, Petar verfasserin aut Wang, Kevin K. W. verfasserin aut Wiegers, Eveline verfasserin aut Williams, Guy verfasserin aut Wilson, Lindsay verfasserin aut Winzeck, Stefan verfasserin aut Wolf, Stefan verfasserin aut Yang, Zhihui verfasserin aut Ylén, Peter verfasserin aut Zeiler, Frederick A. verfasserin aut Ziverte, Agate verfasserin aut Zoerle, Tommaso verfasserin aut Enthalten in The lancet London : Lancet Publ. Group, 2002 21(2022), 7 vom: Juli, Seite 620-631 Online-Ressource (DE-627)348587104 (DE-600)2079704-7 (DE-576)110736362 1474-4465 nnns volume:21 year:2022 number:7 month:07 pages:620-631 extent:12 https://doi.org/10.1016/S1474-4422(22)00166-1 Verlag Resolving-System lizenzpflichtig Volltext https://www.sciencedirect.com/science/article/pii/S1474442222001661 Verlag lizenzpflichtig Volltext GBV_USEFLAG_U GBV_ILN_2013 ISIL_DE-16-250 SYSFLAG_1 GBV_KXP GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 21 2022 7 7 620-631 12 2013 01 DE-16-250 4191345133 00 --%%-- --%%-- --%%-- --%%-- l01 25-09-22 2013 01 DE-16-250 00 s hd2022 2013 01 DE-16-250 01 s (DE-627)1410508463 wissenschaftlicher Artikel (Zeitschrift) 2013 01 DE-16-250 02 s per_255 2013 01 DE-16-250 03 s s_12 2013 01 DE-16-250 04 p (DE-627)1493914448 Younsi, Alexander 2013 01 DE-16-250 04 k (DE-627)141674133X Neurochirurgische Universitätsklinik 2013 01 DE-16-250 04 s (DE-627)1410501914 Verfasser 2013 01 DE-16-250 04 s pos_7 |
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Essen, Thomas van @@aut@@ Lingsma, Hester F @@aut@@ Pisică, Dana @@aut@@ Singh, Ranjit D @@aut@@ Volovici, Victor @@aut@@ den Boogert, Hugo F @@aut@@ Younsi, Alexander @@aut@@ Peppel, Lianne D @@aut@@ Heijenbrok-Kal, Majanka H @@aut@@ Ribbers, Gerard M @@aut@@ Walchenbach, Robert @@aut@@ Menon, David K @@aut@@ Hutchinson, Peter @@aut@@ Depreitere, Bart @@aut@@ Steyerberg, Ewout W @@aut@@ Maas, Andrew I R @@aut@@ de Ruiter, Godard C W @@aut@@ Peul, Wilco C @@aut@@ Åkerlund, Cecilia @@aut@@ Amrein, Krisztina @@aut@@ Andelic, Nada @@aut@@ Andreassen, Lasse @@aut@@ Anke, Audny @@aut@@ Antoni, Anna @@aut@@ Audibert, Gérard @@aut@@ Azouvi, Philippe @@aut@@ Azzolini, Maria Luisa @@aut@@ Bartels, Ronald @@aut@@ Barzó, Pál @@aut@@ Beauvais, Romuald @@aut@@ Beer, Ronny @@aut@@ Bellander, Bo-Michael @@aut@@ Belli, Antonio @@aut@@ Benali, Habib @@aut@@ Berardino, Maurizio @@aut@@ Beretta, Luigi @@aut@@ Blaabjerg, Morten @@aut@@ Bragge, Peter @@aut@@ Brazinova, Alexandra @@aut@@ Brinck, Vibeke 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J. M. @@aut@@ Van Hecke, Wim @@aut@@ van Heugten, Caroline @@aut@@ Van Praag, Dominique @@aut@@ Van Veen, Ernest @@aut@@ van Wijk, Roel @@aut@@ Vande Vyvere, Thijs @@aut@@ Vargiolu, Alessia @@aut@@ Vega, Emmanuel @@aut@@ Velt, Kimberley @@aut@@ Verheyden, Jan @@aut@@ Vespa, Paul M. @@aut@@ Vik, Anne @@aut@@ Vilcinis, Rimantas @@aut@@ von Steinbüchel, Nicole @@aut@@ Voormolen, Daphne @@aut@@ Vulekovic, Petar @@aut@@ Wang, Kevin K. W. @@aut@@ Wiegers, Eveline @@aut@@ Williams, Guy @@aut@@ Wilson, Lindsay @@aut@@ Winzeck, Stefan @@aut@@ Wolf, Stefan @@aut@@ Yang, Zhihui @@aut@@ Ylén, Peter @@aut@@ Zeiler, Frederick A. @@aut@@ Ziverte, Agate @@aut@@ Zoerle, Tommaso @@aut@@ |
| publishDateDaySort_date |
2022-07-01T00:00:00Z |
| hierarchy_top_id |
348587104 |
| id |
1817370863 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a2200265 4500</leader><controlfield tag="001">1817370863</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230118144254.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">220925s2022 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/S1474-4422(22)00166-1</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)1817370863</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)KXP1817370863</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)1361696287</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Essen, Thomas van</subfield><subfield code="e">verfasserin</subfield><subfield code="0">(DE-588)1190840006</subfield><subfield code="0">(DE-627)1669416119</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Surgery versus conservative treatment for traumatic acute subdural haematoma</subfield><subfield code="b">a prospective, multicentre, observational, comparative effectiveness study</subfield><subfield code="c">Thomas A van Essen, Hester F Lingsma, Dana Pisică, Ranjit D Singh, Victor Volovici, Hugo F den Boogert, Alexander Younsi, Lianne D Peppel, Majanka H Heijenbrok-Kal, Gerard M Ribbers, Robert Walchenbach, David K Menon, Peter Hutchinson, Bart Depreitere, Ewout W Steyerberg, Andrew I R Maas, Godard C W de Ruiter, Wilco C Peul, on behalf of the CENTER-TBI Collaboration Group</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">May 5, 2022</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">12</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Gesehen am 25.09.2022</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">CENTER-TBI Collaboration Group: Cecilia Åkerlund, Krisztina Amrein, Nada Andelic, Lasse Andreassen, Audny Anke, Anna Antoni, Gérard Audibert, Philippe Azouvi, Maria Luisa Azzolini, Ronald Bartels, Pál Barzó [und viele weitere]</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background - Despite being well established, acute surgery in traumatic acute subdural haematoma is based on low-grade evidence. We aimed to compare the effectiveness of a strategy preferring acute surgical evacuation with one preferring initial conservative treatment in acute subdural haematoma. - Methods - We did a prospective, observational, comparative effectiveness study using data from participants enrolled in the Collaborative European Neurotrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) cohort. We included patients with no pre-existing severe neurological disorders who presented with acute subdural haematoma within 24 h of traumatic brain injury. Using an instrumental variable analysis, we compared outcomes between centres according to treatment preference for acute subdural haematoma (acute surgical evacuation or initial conservative treatment), measured by the case-mix-adjusted percentage of acute surgery per centre. The primary endpoint was functional outcome at 6 months as rated with the Glasgow Outcome Scale Extended, which was estimated with ordinal regression as a common odds ratio (OR) and adjusted for prespecified confounders. Variation in centre preference was quantified with the median OR (MOR). CENTER-TBI is registered with ClinicalTrials.gov, number NCT02210221, and the Resource Identification Portal (Research Resource Identifier SCR_015582). - Findings - Between Dec 19, 2014 and Dec 17, 2017, 4559 patients with traumatic brain injury were enrolled in CENTER-TBI, of whom 1407 (31%) presented with acute subdural haematoma and were included in our study. Acute surgical evacuation was done in 336 (24%) patients, by craniotomy in 245 (73%) of those patients and by decompressive craniectomy in 91 (27%). Delayed decompressive craniectomy or craniotomy after initial conservative treatment (n=982) occurred in 107 (11%) patients. The percentage of patients who underwent acute surgery ranged from 5·6% to 51·5% (IQR 12·3-35·9) between centres, with a two-times higher probability of receiving acute surgery for an identical patient in one centre versus another centre at random (adjusted MOR for acute surgery 1·8; p<0·0001]). Centre preference for acute surgery over initial conservative treatment was not associated with improvements in functional outcome (common OR per 23·6% [IQR increase] more acute surgery in a centre 0·92, 95% CI 0·77-1·09). - Interpretation - Our findings show that treatment for patients with acute subdural haematoma with similar characteristics differed depending on the treating centre, because of variation in the preferred approach. A treatment strategy preferring an aggressive approach of acute surgical evacuation over initial conservative treatment was not associated with better functional outcome. Therefore, in a patient with acute subdural haematoma for whom a neurosurgeon sees no clear superiority for acute surgery over conservative treatment, initial conservative treatment might be considered. - Funding - The Hersenstichting Nederland (also known as the Dutch Brain Foundation), the European Commission Seventh Framework Programme, the Hannelore Kohl Stiftung (Germany), OneMind (USA), Integra LifeSciences Corporation (USA), and NeuroTrauma Sciences (USA).</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lingsma, Hester F</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Pisică, Dana</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Singh, Ranjit D</subfield><subfield code="e">verfasserin</subfield><subfield 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Surgery versus conservative treatment for traumatic acute subdural haematoma a prospective, multicentre, observational, comparative effectiveness study Thomas A van Essen, Hester F Lingsma, Dana Pisică, Ranjit D Singh, Victor Volovici, Hugo F den Boogert, Alexander Younsi, Lianne D Peppel, Majanka H Heijenbrok-Kal, Gerard M Ribbers, Robert Walchenbach, David K Menon, Peter Hutchinson, Bart Depreitere, Ewout W Steyerberg, Andrew I R Maas, Godard C W de Ruiter, Wilco C Peul, on behalf of the CENTER-TBI Collaboration Group |
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Essen, Thomas van Lingsma, Hester F Pisică, Dana Singh, Ranjit D Volovici, Victor den Boogert, Hugo F Younsi, Alexander Peppel, Lianne D Heijenbrok-Kal, Majanka H Ribbers, Gerard M Walchenbach, Robert Menon, David K Hutchinson, Peter Depreitere, Bart Steyerberg, Ewout W Maas, Andrew I R de Ruiter, Godard C W Peul, Wilco C Åkerlund, Cecilia Amrein, Krisztina Andelic, Nada Andreassen, Lasse Anke, Audny Antoni, Anna Audibert, Gérard Azouvi, Philippe Azzolini, Maria Luisa Bartels, Ronald Barzó, Pál Beauvais, Romuald Beer, Ronny Bellander, Bo-Michael Belli, Antonio Benali, Habib Berardino, Maurizio Beretta, Luigi Blaabjerg, Morten Bragge, Peter Brazinova, Alexandra Brinck, Vibeke Brooker, Joanne Brorsson, Camilla Buki, Andras Bullinger, Monika Cabeleira, Manuel Caccioppola, Alessio Calappi, Emiliana Calvi, Maria Rosa Cameron, Peter Carbayo Lozano, Guillermo Carbonara, Marco Castaño-León, Ana M. Cavallo, Simona Chevallard, Giorgio Chieregato, Arturo Citerio, Giuseppe Clusmann, Hans Coburn, Mark Steven Coles, Jonathan Cooper, Jamie D. Correia, Marta Čović, Amra Curry, Nicola Czeiter, Endre Czosnyka, Marek Dahyot-Fizelier, Claire Dark, Paul Dawes, Helen De Keyser, Véronique Degos, Vincent Della Corte, Francesco Đilvesi, Đula Dixit, Abhishek Donoghue, Emma Dreier, Jens Dulière, Guy-Loup Ercole, Ari Esser, Patrick Ezer, Erzsébet Fabricius, Martin Feigin, Valery L. Foks, Kelly Frisvold, Shirin Furmanov, Alex Gagliardo, Pablo Galanaud, Damien Gantner, Dashiell Gao, Guoyi George, Pradeep Ghuysen, Alexandre Giga, Lelde Glocker, Ben Golubović, Jagoš Gomez, Pedro A. Gratz, Johannes Gravesteijn, Benjamin Grossi, Francesca Gruen, Russell L. Gupta, Deepak Haagsma, Juanita A. Haitsma, Iain Helbok, Raimund Helseth, Eirik Horton, Lindsay Huijben, Jilske Jacobs, Bram Jankowski, Stefan Jarrett, Mike Jiang, Ji-yao Johnson, Faye Jones, Kelly Karan, Mladen Kolias, Angelos G. Kompanje, Erwin Kondziella, Daniel Kornaropoulos, Evgenios Koskinen, Lars-Owe Kovács, Noémi Lagares, Alfonso Lanyon, Linda Laureys, Steven Lecky, Fiona Ledoux, Didier Lefering, Rolf Legrand, Valerie Lejeune, Aurelie Levi, Leon Lightfoot, Roger Maegele, Marc Majdan, Marek Manara, Alex Manley, Geoffrey Maréchal, Hugues Martino, Costanza Mattern, Julia McMahon, Catherine Melegh, Béla Menovsky, Tomas Mikolic, Ana Misset, Benoit Muraleedharan, Visakh Murray, Lynnette Nair, Nandesh Negru, Ancuta Nelson, David Newcombe, Virginia Nieboer, Daan Nyirádi, József Oresic, Matej Ortolano, Fabrizio Otesile, Olubukola Palotie, Aarno Parizel, Paul M. Payen, Jean-François Perera, Natascha Perlbarg, Vincent Persona, Paolo Piippo-Karjalainen, Anna Pirinen, Matti Ples, Horia Polinder, Suzanne Pomposo, Inigo Posti, Jussi P. Puybasset, Louis Rădoi, Andreea Ragauskas, Arminas Raj, Rahul Rambadagalla, Malinka Rehorčíková, Veronika Retel Helmrich, Isabel Rhodes, Jonathan Richardson, Sylvia Richter, Sophie Ripatti, Samuli Rocka, Saulius Roe, Cecilie Roise, Olav Rosand, Jonathan Rosenfeld, Jeffrey Rosenlund, Christina Rosenthal, Guy Rossaint, Rolf Rossi, Sandra Rueckert, Daniel Rusnák, Martin Sahuquillo, Juan Sakowitz, Oliver Sanchez-Porras, Renan Sandor, Janos Schäfer, Nadine Schmidt, Silke Schoechl, Herbert Schoonman, Guus Schou, Rico Frederik Schwendenwein, Elisabeth Sewalt, Charlie Skandsen, Toril Smielewski, Peter Sorinola, Abayomi Stamatakis, Emmanuel Stanworth, Simon Kowark, Ana Stevens, Robert Stewart, William Stocchetti, Nino Sundström, Nina Takala, Riikka Tamás, Viktória Tamosuitis, Tomas Taylor, Mark Steven Te Ao, Braden Tenovuo, Olli Theadom, Alice Thomas, Matt Tibboel, Dick Timmers, Marjolijn Tolias, Christos Trapani, Tony Tudora, Cristina Maria Unterberg, Andreas Vajkoczy, Peter Valeinis, Egils Vallance, Shirley Vámos, Zoltán Van der Jagt, Mathieu van der Naalt, Joukje Van der Steen, Gregory van Dijck, Jeroen T. J. M. Van Hecke, Wim van Heugten, Caroline Van Praag, Dominique Van Veen, Ernest van Wijk, Roel Vande Vyvere, Thijs Vargiolu, Alessia Vega, Emmanuel Velt, Kimberley Verheyden, Jan Vespa, Paul M. Vik, Anne Vilcinis, Rimantas von Steinbüchel, Nicole Voormolen, Daphne Vulekovic, Petar Wang, Kevin K. W. Wiegers, Eveline Williams, Guy Wilson, Lindsay Winzeck, Stefan Wolf, Stefan Yang, Zhihui Ylén, Peter Zeiler, Frederick A. Ziverte, Agate Zoerle, Tommaso |
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surgery versus conservative treatment for traumatic acute subdural haematomaa prospective, multicentre, observational, comparative effectiveness study |
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Surgery versus conservative treatment for traumatic acute subdural haematoma a prospective, multicentre, observational, comparative effectiveness study |
| abstract |
Background - Despite being well established, acute surgery in traumatic acute subdural haematoma is based on low-grade evidence. We aimed to compare the effectiveness of a strategy preferring acute surgical evacuation with one preferring initial conservative treatment in acute subdural haematoma. - Methods - We did a prospective, observational, comparative effectiveness study using data from participants enrolled in the Collaborative European Neurotrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) cohort. We included patients with no pre-existing severe neurological disorders who presented with acute subdural haematoma within 24 h of traumatic brain injury. Using an instrumental variable analysis, we compared outcomes between centres according to treatment preference for acute subdural haematoma (acute surgical evacuation or initial conservative treatment), measured by the case-mix-adjusted percentage of acute surgery per centre. The primary endpoint was functional outcome at 6 months as rated with the Glasgow Outcome Scale Extended, which was estimated with ordinal regression as a common odds ratio (OR) and adjusted for prespecified confounders. Variation in centre preference was quantified with the median OR (MOR). CENTER-TBI is registered with ClinicalTrials.gov, number NCT02210221, and the Resource Identification Portal (Research Resource Identifier SCR_015582). - Findings - Between Dec 19, 2014 and Dec 17, 2017, 4559 patients with traumatic brain injury were enrolled in CENTER-TBI, of whom 1407 (31%) presented with acute subdural haematoma and were included in our study. Acute surgical evacuation was done in 336 (24%) patients, by craniotomy in 245 (73%) of those patients and by decompressive craniectomy in 91 (27%). Delayed decompressive craniectomy or craniotomy after initial conservative treatment (n=982) occurred in 107 (11%) patients. The percentage of patients who underwent acute surgery ranged from 5·6% to 51·5% (IQR 12·3-35·9) between centres, with a two-times higher probability of receiving acute surgery for an identical patient in one centre versus another centre at random (adjusted MOR for acute surgery 1·8; p<0·0001]). Centre preference for acute surgery over initial conservative treatment was not associated with improvements in functional outcome (common OR per 23·6% [IQR increase] more acute surgery in a centre 0·92, 95% CI 0·77-1·09). - Interpretation - Our findings show that treatment for patients with acute subdural haematoma with similar characteristics differed depending on the treating centre, because of variation in the preferred approach. A treatment strategy preferring an aggressive approach of acute surgical evacuation over initial conservative treatment was not associated with better functional outcome. Therefore, in a patient with acute subdural haematoma for whom a neurosurgeon sees no clear superiority for acute surgery over conservative treatment, initial conservative treatment might be considered. - Funding - The Hersenstichting Nederland (also known as the Dutch Brain Foundation), the European Commission Seventh Framework Programme, the Hannelore Kohl Stiftung (Germany), OneMind (USA), Integra LifeSciences Corporation (USA), and NeuroTrauma Sciences (USA). Gesehen am 25.09.2022 CENTER-TBI Collaboration Group: Cecilia Åkerlund, Krisztina Amrein, Nada Andelic, Lasse Andreassen, Audny Anke, Anna Antoni, Gérard Audibert, Philippe Azouvi, Maria Luisa Azzolini, Ronald Bartels, Pál Barzó [und viele weitere] |
| abstractGer |
Background - Despite being well established, acute surgery in traumatic acute subdural haematoma is based on low-grade evidence. We aimed to compare the effectiveness of a strategy preferring acute surgical evacuation with one preferring initial conservative treatment in acute subdural haematoma. - Methods - We did a prospective, observational, comparative effectiveness study using data from participants enrolled in the Collaborative European Neurotrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) cohort. We included patients with no pre-existing severe neurological disorders who presented with acute subdural haematoma within 24 h of traumatic brain injury. Using an instrumental variable analysis, we compared outcomes between centres according to treatment preference for acute subdural haematoma (acute surgical evacuation or initial conservative treatment), measured by the case-mix-adjusted percentage of acute surgery per centre. The primary endpoint was functional outcome at 6 months as rated with the Glasgow Outcome Scale Extended, which was estimated with ordinal regression as a common odds ratio (OR) and adjusted for prespecified confounders. Variation in centre preference was quantified with the median OR (MOR). CENTER-TBI is registered with ClinicalTrials.gov, number NCT02210221, and the Resource Identification Portal (Research Resource Identifier SCR_015582). - Findings - Between Dec 19, 2014 and Dec 17, 2017, 4559 patients with traumatic brain injury were enrolled in CENTER-TBI, of whom 1407 (31%) presented with acute subdural haematoma and were included in our study. Acute surgical evacuation was done in 336 (24%) patients, by craniotomy in 245 (73%) of those patients and by decompressive craniectomy in 91 (27%). Delayed decompressive craniectomy or craniotomy after initial conservative treatment (n=982) occurred in 107 (11%) patients. The percentage of patients who underwent acute surgery ranged from 5·6% to 51·5% (IQR 12·3-35·9) between centres, with a two-times higher probability of receiving acute surgery for an identical patient in one centre versus another centre at random (adjusted MOR for acute surgery 1·8; p<0·0001]). Centre preference for acute surgery over initial conservative treatment was not associated with improvements in functional outcome (common OR per 23·6% [IQR increase] more acute surgery in a centre 0·92, 95% CI 0·77-1·09). - Interpretation - Our findings show that treatment for patients with acute subdural haematoma with similar characteristics differed depending on the treating centre, because of variation in the preferred approach. A treatment strategy preferring an aggressive approach of acute surgical evacuation over initial conservative treatment was not associated with better functional outcome. Therefore, in a patient with acute subdural haematoma for whom a neurosurgeon sees no clear superiority for acute surgery over conservative treatment, initial conservative treatment might be considered. - Funding - The Hersenstichting Nederland (also known as the Dutch Brain Foundation), the European Commission Seventh Framework Programme, the Hannelore Kohl Stiftung (Germany), OneMind (USA), Integra LifeSciences Corporation (USA), and NeuroTrauma Sciences (USA). Gesehen am 25.09.2022 CENTER-TBI Collaboration Group: Cecilia Åkerlund, Krisztina Amrein, Nada Andelic, Lasse Andreassen, Audny Anke, Anna Antoni, Gérard Audibert, Philippe Azouvi, Maria Luisa Azzolini, Ronald Bartels, Pál Barzó [und viele weitere] |
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Background - Despite being well established, acute surgery in traumatic acute subdural haematoma is based on low-grade evidence. We aimed to compare the effectiveness of a strategy preferring acute surgical evacuation with one preferring initial conservative treatment in acute subdural haematoma. - Methods - We did a prospective, observational, comparative effectiveness study using data from participants enrolled in the Collaborative European Neurotrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) cohort. We included patients with no pre-existing severe neurological disorders who presented with acute subdural haematoma within 24 h of traumatic brain injury. Using an instrumental variable analysis, we compared outcomes between centres according to treatment preference for acute subdural haematoma (acute surgical evacuation or initial conservative treatment), measured by the case-mix-adjusted percentage of acute surgery per centre. The primary endpoint was functional outcome at 6 months as rated with the Glasgow Outcome Scale Extended, which was estimated with ordinal regression as a common odds ratio (OR) and adjusted for prespecified confounders. Variation in centre preference was quantified with the median OR (MOR). CENTER-TBI is registered with ClinicalTrials.gov, number NCT02210221, and the Resource Identification Portal (Research Resource Identifier SCR_015582). - Findings - Between Dec 19, 2014 and Dec 17, 2017, 4559 patients with traumatic brain injury were enrolled in CENTER-TBI, of whom 1407 (31%) presented with acute subdural haematoma and were included in our study. Acute surgical evacuation was done in 336 (24%) patients, by craniotomy in 245 (73%) of those patients and by decompressive craniectomy in 91 (27%). Delayed decompressive craniectomy or craniotomy after initial conservative treatment (n=982) occurred in 107 (11%) patients. The percentage of patients who underwent acute surgery ranged from 5·6% to 51·5% (IQR 12·3-35·9) between centres, with a two-times higher probability of receiving acute surgery for an identical patient in one centre versus another centre at random (adjusted MOR for acute surgery 1·8; p<0·0001]). Centre preference for acute surgery over initial conservative treatment was not associated with improvements in functional outcome (common OR per 23·6% [IQR increase] more acute surgery in a centre 0·92, 95% CI 0·77-1·09). - Interpretation - Our findings show that treatment for patients with acute subdural haematoma with similar characteristics differed depending on the treating centre, because of variation in the preferred approach. A treatment strategy preferring an aggressive approach of acute surgical evacuation over initial conservative treatment was not associated with better functional outcome. Therefore, in a patient with acute subdural haematoma for whom a neurosurgeon sees no clear superiority for acute surgery over conservative treatment, initial conservative treatment might be considered. - Funding - The Hersenstichting Nederland (also known as the Dutch Brain Foundation), the European Commission Seventh Framework Programme, the Hannelore Kohl Stiftung (Germany), OneMind (USA), Integra LifeSciences Corporation (USA), and NeuroTrauma Sciences (USA). Gesehen am 25.09.2022 CENTER-TBI Collaboration Group: Cecilia Åkerlund, Krisztina Amrein, Nada Andelic, Lasse Andreassen, Audny Anke, Anna Antoni, Gérard Audibert, Philippe Azouvi, Maria Luisa Azzolini, Ronald Bartels, Pál Barzó [und viele weitere] |
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Surgery versus conservative treatment for traumatic acute subdural haematoma |
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https://doi.org/10.1016/S1474-4422(22)00166-1 https://www.sciencedirect.com/science/article/pii/S1474442222001661 |
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Lingsma, Hester F Pisică, Dana Singh, Ranjit D Volovici, Victor den Boogert, Hugo F Younsi, Alexander 1985- Peppel, Lianne D Heijenbrok-Kal, Majanka H Ribbers, Gerard M Walchenbach, Robert Menon, David K Hutchinson, Peter Depreitere, Bart Steyerberg, Ewout W Maas, Andrew I R de Ruiter, Godard C W Peul, Wilco C Åkerlund, Cecilia Amrein, Krisztina Andelic, Nada Andreassen, Lasse Anke, Audny Antoni, Anna Audibert, Gérard Azouvi, Philippe Azzolini, Maria Luisa Bartels, Ronald Barzó, Pál Beauvais, Romuald Beer, Ronny Bellander, Bo-Michael Belli, Antonio Benali, Habib Berardino, Maurizio Beretta, Luigi Blaabjerg, Morten Bragge, Peter Brazinova, Alexandra Brinck, Vibeke Brooker, Joanne Brorsson, Camilla Buki, Andras Bullinger, Monika Cabeleira, Manuel Caccioppola, Alessio Calappi, Emiliana Calvi, Maria Rosa Cameron, Peter Carbayo Lozano, Guillermo Carbonara, Marco Castaño-León, Ana M. Cavallo, Simona Chevallard, Giorgio Chieregato, Arturo Citerio, Giuseppe Clusmann, Hans Coburn, Mark Steven Coles, Jonathan Cooper, Jamie D. Correia, Marta Čović, Amra Curry, Nicola Czeiter, Endre Czosnyka, Marek Dahyot-Fizelier, Claire Dark, Paul Dawes, Helen De Keyser, Véronique Degos, Vincent Della Corte, Francesco Đilvesi, Đula Dixit, Abhishek Donoghue, Emma Dreier, Jens Dulière, Guy-Loup Ercole, Ari Esser, Patrick Ezer, Erzsébet Fabricius, Martin Feigin, Valery L. Foks, Kelly Frisvold, Shirin Furmanov, Alex Gagliardo, Pablo Galanaud, Damien Gantner, Dashiell Gao, Guoyi George, Pradeep Ghuysen, Alexandre Giga, Lelde Glocker, Ben Golubović, Jagoš Gomez, Pedro A. Gratz, Johannes Gravesteijn, Benjamin Grossi, Francesca Gruen, Russell L. Gupta, Deepak Haagsma, Juanita A. Haitsma, Iain Helbok, Raimund Helseth, Eirik Horton, Lindsay Huijben, Jilske Jacobs, Bram Jankowski, Stefan Jarrett, Mike Jiang, Ji-yao Johnson, Faye Jones, Kelly Karan, Mladen Kolias, Angelos G. Kompanje, Erwin Kondziella, Daniel Kornaropoulos, Evgenios Koskinen, Lars-Owe Kovács, Noémi Lagares, Alfonso Lanyon, Linda Laureys, Steven Lecky, Fiona Ledoux, Didier Lefering, Rolf Legrand, Valerie Lejeune, Aurelie Levi, Leon Lightfoot, Roger Maegele, Marc Majdan, Marek Manara, Alex Manley, Geoffrey Maréchal, Hugues Martino, Costanza Mattern, Julia McMahon, Catherine Melegh, Béla Menovsky, Tomas Mikolic, Ana Misset, Benoit Muraleedharan, Visakh Murray, Lynnette Nair, Nandesh Negru, Ancuta Nelson, David Newcombe, Virginia Nieboer, Daan Nyirádi, József Oresic, Matej Ortolano, Fabrizio Otesile, Olubukola Palotie, Aarno Parizel, Paul M. Payen, Jean-François Perera, Natascha Perlbarg, Vincent Persona, Paolo Piippo-Karjalainen, Anna Pirinen, Matti Ples, Horia Polinder, Suzanne Pomposo, Inigo Posti, Jussi P. Puybasset, Louis Rădoi, Andreea Ragauskas, Arminas Raj, Rahul Rambadagalla, Malinka Rehorčíková, Veronika Retel Helmrich, Isabel Rhodes, Jonathan Richardson, Sylvia Richter, Sophie Ripatti, Samuli Rocka, Saulius Roe, Cecilie Roise, Olav Rosand, Jonathan Rosenfeld, Jeffrey Rosenlund, Christina Rosenthal, Guy Rossaint, Rolf Rossi, Sandra Rueckert, Daniel Rusnák, Martin Sahuquillo, Juan Sakowitz, Oliver Sanchez-Porras, Renan Sandor, Janos Schäfer, Nadine Schmidt, Silke Schoechl, Herbert Schoonman, Guus Schou, Rico Frederik Schwendenwein, Elisabeth Sewalt, Charlie Skandsen, Toril Smielewski, Peter Sorinola, Abayomi Stamatakis, Emmanuel Stanworth, Simon Kowark, Ana Stevens, Robert Stewart, William Stocchetti, Nino Sundström, Nina Takala, Riikka Tamás, Viktória Tamosuitis, Tomas Taylor, Mark Steven Te Ao, Braden Tenovuo, Olli Theadom, Alice Thomas, Matt Tibboel, Dick Timmers, Marjolijn Tolias, Christos Trapani, Tony Tudora, Cristina Maria Unterberg, Andreas Vajkoczy, Peter Valeinis, Egils Vallance, Shirley Vámos, Zoltán Van der Jagt, Mathieu van der Naalt, Joukje Van der Steen, Gregory van Dijck, Jeroen T. J. M. Van Hecke, Wim van Heugten, Caroline Van Praag, Dominique Van Veen, Ernest van Wijk, Roel Vande Vyvere, Thijs Vargiolu, Alessia Vega, Emmanuel Velt, Kimberley Verheyden, Jan Vespa, Paul M. Vik, Anne Vilcinis, Rimantas von Steinbüchel, Nicole Voormolen, Daphne Vulekovic, Petar Wang, Kevin K. W. Wiegers, Eveline Williams, Guy Wilson, Lindsay Winzeck, Stefan Wolf, Stefan Yang, Zhihui Ylén, Peter Zeiler, Frederick A. Ziverte, Agate Zoerle, Tommaso |
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Lingsma, Hester F Pisică, Dana Singh, Ranjit D Volovici, Victor den Boogert, Hugo F Younsi, Alexander 1985- Peppel, Lianne D Heijenbrok-Kal, Majanka H Ribbers, Gerard M Walchenbach, Robert Menon, David K Hutchinson, Peter Depreitere, Bart Steyerberg, Ewout W Maas, Andrew I R de Ruiter, Godard C W Peul, Wilco C Åkerlund, Cecilia Amrein, Krisztina Andelic, Nada Andreassen, Lasse Anke, Audny Antoni, Anna Audibert, Gérard Azouvi, Philippe Azzolini, Maria Luisa Bartels, Ronald Barzó, Pál Beauvais, Romuald Beer, Ronny Bellander, Bo-Michael Belli, Antonio Benali, Habib Berardino, Maurizio Beretta, Luigi Blaabjerg, Morten Bragge, Peter Brazinova, Alexandra Brinck, Vibeke Brooker, Joanne Brorsson, Camilla Buki, Andras Bullinger, Monika Cabeleira, Manuel Caccioppola, Alessio Calappi, Emiliana Calvi, Maria Rosa Cameron, Peter Carbayo Lozano, Guillermo Carbonara, Marco Castaño-León, Ana M. Cavallo, Simona Chevallard, Giorgio Chieregato, Arturo Citerio, Giuseppe Clusmann, Hans Coburn, Mark Steven Coles, Jonathan Cooper, Jamie D. Correia, Marta Čović, Amra Curry, Nicola Czeiter, Endre Czosnyka, Marek Dahyot-Fizelier, Claire Dark, Paul Dawes, Helen De Keyser, Véronique Degos, Vincent Della Corte, Francesco Đilvesi, Đula Dixit, Abhishek Donoghue, Emma Dreier, Jens Dulière, Guy-Loup Ercole, Ari Esser, Patrick Ezer, Erzsébet Fabricius, Martin Feigin, Valery L. Foks, Kelly Frisvold, Shirin Furmanov, Alex Gagliardo, Pablo Galanaud, Damien Gantner, Dashiell Gao, Guoyi George, Pradeep Ghuysen, Alexandre Giga, Lelde Glocker, Ben Golubović, Jagoš Gomez, Pedro A. Gratz, Johannes Gravesteijn, Benjamin Grossi, Francesca Gruen, Russell L. Gupta, Deepak Haagsma, Juanita A. Haitsma, Iain Helbok, Raimund Helseth, Eirik Horton, Lindsay Huijben, Jilske Jacobs, Bram Jankowski, Stefan Jarrett, Mike Jiang, Ji-yao Johnson, Faye Jones, Kelly Karan, Mladen Kolias, Angelos G. Kompanje, Erwin Kondziella, Daniel Kornaropoulos, Evgenios Koskinen, Lars-Owe Kovács, Noémi Lagares, Alfonso Lanyon, Linda Laureys, Steven Lecky, Fiona Ledoux, Didier Lefering, Rolf Legrand, Valerie Lejeune, Aurelie Levi, Leon Lightfoot, Roger Maegele, Marc Majdan, Marek Manara, Alex Manley, Geoffrey Maréchal, Hugues Martino, Costanza Mattern, Julia McMahon, Catherine Melegh, Béla Menovsky, Tomas Mikolic, Ana Misset, Benoit Muraleedharan, Visakh Murray, Lynnette Nair, Nandesh Negru, Ancuta Nelson, David Newcombe, Virginia Nieboer, Daan Nyirádi, József Oresic, Matej Ortolano, Fabrizio Otesile, Olubukola Palotie, Aarno Parizel, Paul M. Payen, Jean-François Perera, Natascha Perlbarg, Vincent Persona, Paolo Piippo-Karjalainen, Anna Pirinen, Matti Ples, Horia Polinder, Suzanne Pomposo, Inigo Posti, Jussi P. Puybasset, Louis Rădoi, Andreea Ragauskas, Arminas Raj, Rahul Rambadagalla, Malinka Rehorčíková, Veronika Retel Helmrich, Isabel Rhodes, Jonathan Richardson, Sylvia Richter, Sophie Ripatti, Samuli Rocka, Saulius Roe, Cecilie Roise, Olav Rosand, Jonathan Rosenfeld, Jeffrey Rosenlund, Christina Rosenthal, Guy Rossaint, Rolf Rossi, Sandra Rueckert, Daniel Rusnák, Martin Sahuquillo, Juan Sakowitz, Oliver Sanchez-Porras, Renan Sandor, Janos Schäfer, Nadine Schmidt, Silke Schoechl, Herbert Schoonman, Guus Schou, Rico Frederik Schwendenwein, Elisabeth Sewalt, Charlie Skandsen, Toril Smielewski, Peter Sorinola, Abayomi Stamatakis, Emmanuel Stanworth, Simon Kowark, Ana Stevens, Robert Stewart, William Stocchetti, Nino Sundström, Nina Takala, Riikka Tamás, Viktória Tamosuitis, Tomas Taylor, Mark Steven Te Ao, Braden Tenovuo, Olli Theadom, Alice Thomas, Matt Tibboel, Dick Timmers, Marjolijn Tolias, Christos Trapani, Tony Tudora, Cristina Maria Unterberg, Andreas Vajkoczy, Peter Valeinis, Egils Vallance, Shirley Vámos, Zoltán Van der Jagt, Mathieu van der Naalt, Joukje Van der Steen, Gregory van Dijck, Jeroen T. J. M. Van Hecke, Wim van Heugten, Caroline Van Praag, Dominique Van Veen, Ernest van Wijk, Roel Vande Vyvere, Thijs Vargiolu, Alessia Vega, Emmanuel Velt, Kimberley Verheyden, Jan Vespa, Paul M. Vik, Anne Vilcinis, Rimantas von Steinbüchel, Nicole Voormolen, Daphne Vulekovic, Petar Wang, Kevin K. W. Wiegers, Eveline Williams, Guy Wilson, Lindsay Winzeck, Stefan Wolf, Stefan Yang, Zhihui Ylén, Peter Zeiler, Frederick A. Ziverte, Agate Zoerle, Tommaso |
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