An all metasurface-based fiber needle probe for Raman spectroscopy

Optical fiber-based spectroscopy sensors are widely used for industrial and biomedical applications. They normally consist of at least one excitation fiber and one collection fiber. However, the excitation and collection fibers are placed side by side, so the focal spots do not coincide. In addition...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Shuyan Zhang [verfasserIn] Renzhe Bi [verfasserIn] Ruochong Zhang [verfasserIn] Yi Qi [verfasserIn] Rasyiqah Bte Shaik Mohamed Salim [verfasserIn] Malini Olivo [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	metasurface fiber Raman spectroscopy biosensing achromatic

Übergeordnetes Werk:	In: Frontiers in Physics - Frontiers Media S.A., 2014, 10(2022)
Übergeordnetes Werk:	volume:10 ; year:2022

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3389/fphy.2022.1093284

Katalog-ID:	DOAJ00113146X

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520			\|a Optical fiber-based spectroscopy sensors are widely used for industrial and biomedical applications. They normally consist of at least one excitation fiber and one collection fiber. However, the excitation and collection fibers are placed side by side, so the focal spots do not coincide. In addition, Raman probes whose excitation and emission span a wide wavelength range are limited by wavelength-dependent focal length variation, low sensitivity, and bulky size impeding their clinical adoption. To overcome the challenges, we propose an all metasurface integrated fiber solution. The metasurface technology is well suited for this application because it relies on specially designed nanostructures to manipulate light properties in an ultrathin footprint. Here we used our earlier demonstrated dual-wavelength excitation Raman probe as an example. The two excitation fibers at 671 nm and 785 nm feature a hybrid metasurface lens (metalens) including a narrow band pass filter and an off-axis focusing metalens. The collection fiber at 810—910 nm features an achromatic broadband on-axis focusing metalens. Simulation results show that by integrating the metalenses, the focal spots of the excitation beams and the collection beam coincide with a beam size of 4.6 µm, 4.6 µm, and 11.3 µm in the x-, y-, and z-axis, respectively. Moreover, the probe size shrinks by 100 times and becomes a needle probe. The needle probe will enable new applications such as small animal in vivo experiments, medical endoscopy experiments, and neonatal skin analysis for hard-to-reach areas. Furthermore, the proposed solution can be applied to work with any optical fiber-based spectroscopy sensors because the designs can be readily fabricated and put into practical use.
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allfields	10.3389/fphy.2022.1093284 doi (DE-627)DOAJ00113146X (DE-599)DOAJ2429293f3087466fbbe81fb9ae7a82d5 DE-627 ger DE-627 rakwb eng QC1-999 Shuyan Zhang verfasserin aut An all metasurface-based fiber needle probe for Raman spectroscopy 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Optical fiber-based spectroscopy sensors are widely used for industrial and biomedical applications. They normally consist of at least one excitation fiber and one collection fiber. However, the excitation and collection fibers are placed side by side, so the focal spots do not coincide. In addition, Raman probes whose excitation and emission span a wide wavelength range are limited by wavelength-dependent focal length variation, low sensitivity, and bulky size impeding their clinical adoption. To overcome the challenges, we propose an all metasurface integrated fiber solution. The metasurface technology is well suited for this application because it relies on specially designed nanostructures to manipulate light properties in an ultrathin footprint. Here we used our earlier demonstrated dual-wavelength excitation Raman probe as an example. The two excitation fibers at 671 nm and 785 nm feature a hybrid metasurface lens (metalens) including a narrow band pass filter and an off-axis focusing metalens. The collection fiber at 810—910 nm features an achromatic broadband on-axis focusing metalens. Simulation results show that by integrating the metalenses, the focal spots of the excitation beams and the collection beam coincide with a beam size of 4.6 µm, 4.6 µm, and 11.3 µm in the x-, y-, and z-axis, respectively. Moreover, the probe size shrinks by 100 times and becomes a needle probe. The needle probe will enable new applications such as small animal in vivo experiments, medical endoscopy experiments, and neonatal skin analysis for hard-to-reach areas. Furthermore, the proposed solution can be applied to work with any optical fiber-based spectroscopy sensors because the designs can be readily fabricated and put into practical use. metasurface fiber Raman spectroscopy biosensing achromatic Physics Renzhe Bi verfasserin aut Ruochong Zhang verfasserin aut Yi Qi verfasserin aut Rasyiqah Bte Shaik Mohamed Salim verfasserin aut Rasyiqah Bte Shaik Mohamed Salim verfasserin aut Malini Olivo verfasserin aut In Frontiers in Physics Frontiers Media S.A., 2014 10(2022) (DE-627)750371749 (DE-600)2721033-9 2296424X nnns volume:10 year:2022 https://doi.org/10.3389/fphy.2022.1093284 kostenfrei https://doaj.org/article/2429293f3087466fbbe81fb9ae7a82d5 kostenfrei https://www.frontiersin.org/articles/10.3389/fphy.2022.1093284/full kostenfrei https://doaj.org/toc/2296-424X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2022
spelling	10.3389/fphy.2022.1093284 doi (DE-627)DOAJ00113146X (DE-599)DOAJ2429293f3087466fbbe81fb9ae7a82d5 DE-627 ger DE-627 rakwb eng QC1-999 Shuyan Zhang verfasserin aut An all metasurface-based fiber needle probe for Raman spectroscopy 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Optical fiber-based spectroscopy sensors are widely used for industrial and biomedical applications. They normally consist of at least one excitation fiber and one collection fiber. However, the excitation and collection fibers are placed side by side, so the focal spots do not coincide. In addition, Raman probes whose excitation and emission span a wide wavelength range are limited by wavelength-dependent focal length variation, low sensitivity, and bulky size impeding their clinical adoption. To overcome the challenges, we propose an all metasurface integrated fiber solution. The metasurface technology is well suited for this application because it relies on specially designed nanostructures to manipulate light properties in an ultrathin footprint. Here we used our earlier demonstrated dual-wavelength excitation Raman probe as an example. The two excitation fibers at 671 nm and 785 nm feature a hybrid metasurface lens (metalens) including a narrow band pass filter and an off-axis focusing metalens. The collection fiber at 810—910 nm features an achromatic broadband on-axis focusing metalens. Simulation results show that by integrating the metalenses, the focal spots of the excitation beams and the collection beam coincide with a beam size of 4.6 µm, 4.6 µm, and 11.3 µm in the x-, y-, and z-axis, respectively. Moreover, the probe size shrinks by 100 times and becomes a needle probe. The needle probe will enable new applications such as small animal in vivo experiments, medical endoscopy experiments, and neonatal skin analysis for hard-to-reach areas. Furthermore, the proposed solution can be applied to work with any optical fiber-based spectroscopy sensors because the designs can be readily fabricated and put into practical use. metasurface fiber Raman spectroscopy biosensing achromatic Physics Renzhe Bi verfasserin aut Ruochong Zhang verfasserin aut Yi Qi verfasserin aut Rasyiqah Bte Shaik Mohamed Salim verfasserin aut Rasyiqah Bte Shaik Mohamed Salim verfasserin aut Malini Olivo verfasserin aut In Frontiers in Physics Frontiers Media S.A., 2014 10(2022) (DE-627)750371749 (DE-600)2721033-9 2296424X nnns volume:10 year:2022 https://doi.org/10.3389/fphy.2022.1093284 kostenfrei https://doaj.org/article/2429293f3087466fbbe81fb9ae7a82d5 kostenfrei https://www.frontiersin.org/articles/10.3389/fphy.2022.1093284/full kostenfrei https://doaj.org/toc/2296-424X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2022
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allfieldsGer	10.3389/fphy.2022.1093284 doi (DE-627)DOAJ00113146X (DE-599)DOAJ2429293f3087466fbbe81fb9ae7a82d5 DE-627 ger DE-627 rakwb eng QC1-999 Shuyan Zhang verfasserin aut An all metasurface-based fiber needle probe for Raman spectroscopy 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Optical fiber-based spectroscopy sensors are widely used for industrial and biomedical applications. They normally consist of at least one excitation fiber and one collection fiber. However, the excitation and collection fibers are placed side by side, so the focal spots do not coincide. In addition, Raman probes whose excitation and emission span a wide wavelength range are limited by wavelength-dependent focal length variation, low sensitivity, and bulky size impeding their clinical adoption. To overcome the challenges, we propose an all metasurface integrated fiber solution. The metasurface technology is well suited for this application because it relies on specially designed nanostructures to manipulate light properties in an ultrathin footprint. Here we used our earlier demonstrated dual-wavelength excitation Raman probe as an example. The two excitation fibers at 671 nm and 785 nm feature a hybrid metasurface lens (metalens) including a narrow band pass filter and an off-axis focusing metalens. The collection fiber at 810—910 nm features an achromatic broadband on-axis focusing metalens. Simulation results show that by integrating the metalenses, the focal spots of the excitation beams and the collection beam coincide with a beam size of 4.6 µm, 4.6 µm, and 11.3 µm in the x-, y-, and z-axis, respectively. Moreover, the probe size shrinks by 100 times and becomes a needle probe. The needle probe will enable new applications such as small animal in vivo experiments, medical endoscopy experiments, and neonatal skin analysis for hard-to-reach areas. Furthermore, the proposed solution can be applied to work with any optical fiber-based spectroscopy sensors because the designs can be readily fabricated and put into practical use. metasurface fiber Raman spectroscopy biosensing achromatic Physics Renzhe Bi verfasserin aut Ruochong Zhang verfasserin aut Yi Qi verfasserin aut Rasyiqah Bte Shaik Mohamed Salim verfasserin aut Rasyiqah Bte Shaik Mohamed Salim verfasserin aut Malini Olivo verfasserin aut In Frontiers in Physics Frontiers Media S.A., 2014 10(2022) (DE-627)750371749 (DE-600)2721033-9 2296424X nnns volume:10 year:2022 https://doi.org/10.3389/fphy.2022.1093284 kostenfrei https://doaj.org/article/2429293f3087466fbbe81fb9ae7a82d5 kostenfrei https://www.frontiersin.org/articles/10.3389/fphy.2022.1093284/full kostenfrei https://doaj.org/toc/2296-424X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2022
allfieldsSound	10.3389/fphy.2022.1093284 doi (DE-627)DOAJ00113146X (DE-599)DOAJ2429293f3087466fbbe81fb9ae7a82d5 DE-627 ger DE-627 rakwb eng QC1-999 Shuyan Zhang verfasserin aut An all metasurface-based fiber needle probe for Raman spectroscopy 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Optical fiber-based spectroscopy sensors are widely used for industrial and biomedical applications. They normally consist of at least one excitation fiber and one collection fiber. However, the excitation and collection fibers are placed side by side, so the focal spots do not coincide. In addition, Raman probes whose excitation and emission span a wide wavelength range are limited by wavelength-dependent focal length variation, low sensitivity, and bulky size impeding their clinical adoption. To overcome the challenges, we propose an all metasurface integrated fiber solution. The metasurface technology is well suited for this application because it relies on specially designed nanostructures to manipulate light properties in an ultrathin footprint. Here we used our earlier demonstrated dual-wavelength excitation Raman probe as an example. The two excitation fibers at 671 nm and 785 nm feature a hybrid metasurface lens (metalens) including a narrow band pass filter and an off-axis focusing metalens. The collection fiber at 810—910 nm features an achromatic broadband on-axis focusing metalens. Simulation results show that by integrating the metalenses, the focal spots of the excitation beams and the collection beam coincide with a beam size of 4.6 µm, 4.6 µm, and 11.3 µm in the x-, y-, and z-axis, respectively. Moreover, the probe size shrinks by 100 times and becomes a needle probe. The needle probe will enable new applications such as small animal in vivo experiments, medical endoscopy experiments, and neonatal skin analysis for hard-to-reach areas. Furthermore, the proposed solution can be applied to work with any optical fiber-based spectroscopy sensors because the designs can be readily fabricated and put into practical use. metasurface fiber Raman spectroscopy biosensing achromatic Physics Renzhe Bi verfasserin aut Ruochong Zhang verfasserin aut Yi Qi verfasserin aut Rasyiqah Bte Shaik Mohamed Salim verfasserin aut Rasyiqah Bte Shaik Mohamed Salim verfasserin aut Malini Olivo verfasserin aut In Frontiers in Physics Frontiers Media S.A., 2014 10(2022) (DE-627)750371749 (DE-600)2721033-9 2296424X nnns volume:10 year:2022 https://doi.org/10.3389/fphy.2022.1093284 kostenfrei https://doaj.org/article/2429293f3087466fbbe81fb9ae7a82d5 kostenfrei https://www.frontiersin.org/articles/10.3389/fphy.2022.1093284/full kostenfrei https://doaj.org/toc/2296-424X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2022
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callnumber-first	Q - Science
author	Shuyan Zhang
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topic_title	QC1-999 An all metasurface-based fiber needle probe for Raman spectroscopy metasurface fiber Raman spectroscopy biosensing achromatic
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title	An all metasurface-based fiber needle probe for Raman spectroscopy
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title_sort	all metasurface-based fiber needle probe for raman spectroscopy
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title_auth	An all metasurface-based fiber needle probe for Raman spectroscopy
abstract	Optical fiber-based spectroscopy sensors are widely used for industrial and biomedical applications. They normally consist of at least one excitation fiber and one collection fiber. However, the excitation and collection fibers are placed side by side, so the focal spots do not coincide. In addition, Raman probes whose excitation and emission span a wide wavelength range are limited by wavelength-dependent focal length variation, low sensitivity, and bulky size impeding their clinical adoption. To overcome the challenges, we propose an all metasurface integrated fiber solution. The metasurface technology is well suited for this application because it relies on specially designed nanostructures to manipulate light properties in an ultrathin footprint. Here we used our earlier demonstrated dual-wavelength excitation Raman probe as an example. The two excitation fibers at 671 nm and 785 nm feature a hybrid metasurface lens (metalens) including a narrow band pass filter and an off-axis focusing metalens. The collection fiber at 810—910 nm features an achromatic broadband on-axis focusing metalens. Simulation results show that by integrating the metalenses, the focal spots of the excitation beams and the collection beam coincide with a beam size of 4.6 µm, 4.6 µm, and 11.3 µm in the x-, y-, and z-axis, respectively. Moreover, the probe size shrinks by 100 times and becomes a needle probe. The needle probe will enable new applications such as small animal in vivo experiments, medical endoscopy experiments, and neonatal skin analysis for hard-to-reach areas. Furthermore, the proposed solution can be applied to work with any optical fiber-based spectroscopy sensors because the designs can be readily fabricated and put into practical use.
abstractGer	Optical fiber-based spectroscopy sensors are widely used for industrial and biomedical applications. They normally consist of at least one excitation fiber and one collection fiber. However, the excitation and collection fibers are placed side by side, so the focal spots do not coincide. In addition, Raman probes whose excitation and emission span a wide wavelength range are limited by wavelength-dependent focal length variation, low sensitivity, and bulky size impeding their clinical adoption. To overcome the challenges, we propose an all metasurface integrated fiber solution. The metasurface technology is well suited for this application because it relies on specially designed nanostructures to manipulate light properties in an ultrathin footprint. Here we used our earlier demonstrated dual-wavelength excitation Raman probe as an example. The two excitation fibers at 671 nm and 785 nm feature a hybrid metasurface lens (metalens) including a narrow band pass filter and an off-axis focusing metalens. The collection fiber at 810—910 nm features an achromatic broadband on-axis focusing metalens. Simulation results show that by integrating the metalenses, the focal spots of the excitation beams and the collection beam coincide with a beam size of 4.6 µm, 4.6 µm, and 11.3 µm in the x-, y-, and z-axis, respectively. Moreover, the probe size shrinks by 100 times and becomes a needle probe. The needle probe will enable new applications such as small animal in vivo experiments, medical endoscopy experiments, and neonatal skin analysis for hard-to-reach areas. Furthermore, the proposed solution can be applied to work with any optical fiber-based spectroscopy sensors because the designs can be readily fabricated and put into practical use.
abstract_unstemmed	Optical fiber-based spectroscopy sensors are widely used for industrial and biomedical applications. They normally consist of at least one excitation fiber and one collection fiber. However, the excitation and collection fibers are placed side by side, so the focal spots do not coincide. In addition, Raman probes whose excitation and emission span a wide wavelength range are limited by wavelength-dependent focal length variation, low sensitivity, and bulky size impeding their clinical adoption. To overcome the challenges, we propose an all metasurface integrated fiber solution. The metasurface technology is well suited for this application because it relies on specially designed nanostructures to manipulate light properties in an ultrathin footprint. Here we used our earlier demonstrated dual-wavelength excitation Raman probe as an example. The two excitation fibers at 671 nm and 785 nm feature a hybrid metasurface lens (metalens) including a narrow band pass filter and an off-axis focusing metalens. The collection fiber at 810—910 nm features an achromatic broadband on-axis focusing metalens. Simulation results show that by integrating the metalenses, the focal spots of the excitation beams and the collection beam coincide with a beam size of 4.6 µm, 4.6 µm, and 11.3 µm in the x-, y-, and z-axis, respectively. Moreover, the probe size shrinks by 100 times and becomes a needle probe. The needle probe will enable new applications such as small animal in vivo experiments, medical endoscopy experiments, and neonatal skin analysis for hard-to-reach areas. Furthermore, the proposed solution can be applied to work with any optical fiber-based spectroscopy sensors because the designs can be readily fabricated and put into practical use.
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title_short	An all metasurface-based fiber needle probe for Raman spectroscopy
url	https://doi.org/10.3389/fphy.2022.1093284 https://doaj.org/article/2429293f3087466fbbe81fb9ae7a82d5 https://www.frontiersin.org/articles/10.3389/fphy.2022.1093284/full https://doaj.org/toc/2296-424X
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up_date	2024-07-03T18:35:29.966Z
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An all metasurface-based fiber needle probe for Raman spectroscopy

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