Chronic Triple Infection with Hepatitis B, C, and D Viruses in the Republic of Sakha (Yakutia)
The purpose of this work was to study the features of the clinical course of mixed infections with hepatitis B+C+D viruses in the Republic of Sakha (Yakutia) (RS(Y)). Materials and Methods: The incidences of these infections were studied in the infectious disease department of the Yakutsk City Clini...
Ausführliche Beschreibung
Autor*in: |
Lubov I. Petrova [verfasserIn] Snezhana S. Sleptsova [verfasserIn] Maksim N. Andreev [verfasserIn] Nikolai M. Gogolev [verfasserIn] Anastasia N. Petrova [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2018 |
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Übergeordnetes Werk: |
In: International Journal of Biomedicine - International Medical Research and Development Corporation, 2013, 8(2018), 3, Seite 217-219 |
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Übergeordnetes Werk: |
volume:8 ; year:2018 ; number:3 ; pages:217-219 |
Links: |
Link aufrufen |
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DOI / URN: |
10.21103/Article8(3)_OA9 |
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Katalog-ID: |
DOAJ001229656 |
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10.21103/Article8(3)_OA9 doi (DE-627)DOAJ001229656 (DE-599)DOAJ57fec4d1b8e34e329ee514c55240e48a DE-627 ger DE-627 rakwb eng Lubov I. Petrova verfasserin aut Chronic Triple Infection with Hepatitis B, C, and D Viruses in the Republic of Sakha (Yakutia) 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The purpose of this work was to study the features of the clinical course of mixed infections with hepatitis B+C+D viruses in the Republic of Sakha (Yakutia) (RS(Y)). Materials and Methods: The incidences of these infections were studied in the infectious disease department of the Yakutsk City Clinical Hospital. A total of 74 patients with chronic infection with hepatitis B, C, and D viruses were analyzed. The following markers of HBV (HBsAg, HBeAg, anti-HBcIgG, HBV DNA), HCV (anti-HCV) and HDV (anti-HDV, HDV RNA) were detected. According to PCR (n=35), HCV-RNA was detected in 29(82.8%) patients. In 65.8% of cases, HCV-RNA replication was observed in the absence of HDV-DNA. Mono-replication of HBV (HBV-DNA+, HCV-RNA-) was detected in 17.1% patients, mono-replication of HCV (HBV-DNA-, HCV-RNA+) in 65.7% patients and mixed replication of viruses C, D and/or G (HBV-DNA-, HCV-RNA+, HDV-RNA+/HGV-RNA+) in 17.1% patients. Results: The comparison of biochemical parameters of patients with chronic mixed hepatitis showed that more expressed changes are observed with the mixed replication than with the mono-replicative form of hepatitis. chronic mixed hepatitis hepatitis B virus hepatitis C virus hepatitis D virus Medicine R Snezhana S. Sleptsova verfasserin aut Maksim N. Andreev verfasserin aut Nikolai M. Gogolev verfasserin aut Anastasia N. Petrova verfasserin aut In International Journal of Biomedicine International Medical Research and Development Corporation, 2013 8(2018), 3, Seite 217-219 (DE-627)741171996 (DE-600)2710779-6 21580529 nnns volume:8 year:2018 number:3 pages:217-219 https://doi.org/10.21103/Article8(3)_OA9 kostenfrei https://doaj.org/article/57fec4d1b8e34e329ee514c55240e48a kostenfrei http://ijbm.org/articles/IJBM_8(3)_OA9.pdf kostenfrei https://doaj.org/toc/2158-0510 Journal toc kostenfrei https://doaj.org/toc/2158-0529 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2018 3 217-219 |
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10.21103/Article8(3)_OA9 doi (DE-627)DOAJ001229656 (DE-599)DOAJ57fec4d1b8e34e329ee514c55240e48a DE-627 ger DE-627 rakwb eng Lubov I. Petrova verfasserin aut Chronic Triple Infection with Hepatitis B, C, and D Viruses in the Republic of Sakha (Yakutia) 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The purpose of this work was to study the features of the clinical course of mixed infections with hepatitis B+C+D viruses in the Republic of Sakha (Yakutia) (RS(Y)). Materials and Methods: The incidences of these infections were studied in the infectious disease department of the Yakutsk City Clinical Hospital. A total of 74 patients with chronic infection with hepatitis B, C, and D viruses were analyzed. The following markers of HBV (HBsAg, HBeAg, anti-HBcIgG, HBV DNA), HCV (anti-HCV) and HDV (anti-HDV, HDV RNA) were detected. According to PCR (n=35), HCV-RNA was detected in 29(82.8%) patients. In 65.8% of cases, HCV-RNA replication was observed in the absence of HDV-DNA. Mono-replication of HBV (HBV-DNA+, HCV-RNA-) was detected in 17.1% patients, mono-replication of HCV (HBV-DNA-, HCV-RNA+) in 65.7% patients and mixed replication of viruses C, D and/or G (HBV-DNA-, HCV-RNA+, HDV-RNA+/HGV-RNA+) in 17.1% patients. Results: The comparison of biochemical parameters of patients with chronic mixed hepatitis showed that more expressed changes are observed with the mixed replication than with the mono-replicative form of hepatitis. chronic mixed hepatitis hepatitis B virus hepatitis C virus hepatitis D virus Medicine R Snezhana S. Sleptsova verfasserin aut Maksim N. Andreev verfasserin aut Nikolai M. Gogolev verfasserin aut Anastasia N. Petrova verfasserin aut In International Journal of Biomedicine International Medical Research and Development Corporation, 2013 8(2018), 3, Seite 217-219 (DE-627)741171996 (DE-600)2710779-6 21580529 nnns volume:8 year:2018 number:3 pages:217-219 https://doi.org/10.21103/Article8(3)_OA9 kostenfrei https://doaj.org/article/57fec4d1b8e34e329ee514c55240e48a kostenfrei http://ijbm.org/articles/IJBM_8(3)_OA9.pdf kostenfrei https://doaj.org/toc/2158-0510 Journal toc kostenfrei https://doaj.org/toc/2158-0529 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2018 3 217-219 |
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10.21103/Article8(3)_OA9 doi (DE-627)DOAJ001229656 (DE-599)DOAJ57fec4d1b8e34e329ee514c55240e48a DE-627 ger DE-627 rakwb eng Lubov I. Petrova verfasserin aut Chronic Triple Infection with Hepatitis B, C, and D Viruses in the Republic of Sakha (Yakutia) 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The purpose of this work was to study the features of the clinical course of mixed infections with hepatitis B+C+D viruses in the Republic of Sakha (Yakutia) (RS(Y)). Materials and Methods: The incidences of these infections were studied in the infectious disease department of the Yakutsk City Clinical Hospital. A total of 74 patients with chronic infection with hepatitis B, C, and D viruses were analyzed. The following markers of HBV (HBsAg, HBeAg, anti-HBcIgG, HBV DNA), HCV (anti-HCV) and HDV (anti-HDV, HDV RNA) were detected. According to PCR (n=35), HCV-RNA was detected in 29(82.8%) patients. In 65.8% of cases, HCV-RNA replication was observed in the absence of HDV-DNA. Mono-replication of HBV (HBV-DNA+, HCV-RNA-) was detected in 17.1% patients, mono-replication of HCV (HBV-DNA-, HCV-RNA+) in 65.7% patients and mixed replication of viruses C, D and/or G (HBV-DNA-, HCV-RNA+, HDV-RNA+/HGV-RNA+) in 17.1% patients. Results: The comparison of biochemical parameters of patients with chronic mixed hepatitis showed that more expressed changes are observed with the mixed replication than with the mono-replicative form of hepatitis. chronic mixed hepatitis hepatitis B virus hepatitis C virus hepatitis D virus Medicine R Snezhana S. Sleptsova verfasserin aut Maksim N. Andreev verfasserin aut Nikolai M. Gogolev verfasserin aut Anastasia N. Petrova verfasserin aut In International Journal of Biomedicine International Medical Research and Development Corporation, 2013 8(2018), 3, Seite 217-219 (DE-627)741171996 (DE-600)2710779-6 21580529 nnns volume:8 year:2018 number:3 pages:217-219 https://doi.org/10.21103/Article8(3)_OA9 kostenfrei https://doaj.org/article/57fec4d1b8e34e329ee514c55240e48a kostenfrei http://ijbm.org/articles/IJBM_8(3)_OA9.pdf kostenfrei https://doaj.org/toc/2158-0510 Journal toc kostenfrei https://doaj.org/toc/2158-0529 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2018 3 217-219 |
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10.21103/Article8(3)_OA9 doi (DE-627)DOAJ001229656 (DE-599)DOAJ57fec4d1b8e34e329ee514c55240e48a DE-627 ger DE-627 rakwb eng Lubov I. Petrova verfasserin aut Chronic Triple Infection with Hepatitis B, C, and D Viruses in the Republic of Sakha (Yakutia) 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The purpose of this work was to study the features of the clinical course of mixed infections with hepatitis B+C+D viruses in the Republic of Sakha (Yakutia) (RS(Y)). Materials and Methods: The incidences of these infections were studied in the infectious disease department of the Yakutsk City Clinical Hospital. A total of 74 patients with chronic infection with hepatitis B, C, and D viruses were analyzed. The following markers of HBV (HBsAg, HBeAg, anti-HBcIgG, HBV DNA), HCV (anti-HCV) and HDV (anti-HDV, HDV RNA) were detected. According to PCR (n=35), HCV-RNA was detected in 29(82.8%) patients. In 65.8% of cases, HCV-RNA replication was observed in the absence of HDV-DNA. Mono-replication of HBV (HBV-DNA+, HCV-RNA-) was detected in 17.1% patients, mono-replication of HCV (HBV-DNA-, HCV-RNA+) in 65.7% patients and mixed replication of viruses C, D and/or G (HBV-DNA-, HCV-RNA+, HDV-RNA+/HGV-RNA+) in 17.1% patients. Results: The comparison of biochemical parameters of patients with chronic mixed hepatitis showed that more expressed changes are observed with the mixed replication than with the mono-replicative form of hepatitis. chronic mixed hepatitis hepatitis B virus hepatitis C virus hepatitis D virus Medicine R Snezhana S. Sleptsova verfasserin aut Maksim N. Andreev verfasserin aut Nikolai M. Gogolev verfasserin aut Anastasia N. Petrova verfasserin aut In International Journal of Biomedicine International Medical Research and Development Corporation, 2013 8(2018), 3, Seite 217-219 (DE-627)741171996 (DE-600)2710779-6 21580529 nnns volume:8 year:2018 number:3 pages:217-219 https://doi.org/10.21103/Article8(3)_OA9 kostenfrei https://doaj.org/article/57fec4d1b8e34e329ee514c55240e48a kostenfrei http://ijbm.org/articles/IJBM_8(3)_OA9.pdf kostenfrei https://doaj.org/toc/2158-0510 Journal toc kostenfrei https://doaj.org/toc/2158-0529 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2018 3 217-219 |
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10.21103/Article8(3)_OA9 doi (DE-627)DOAJ001229656 (DE-599)DOAJ57fec4d1b8e34e329ee514c55240e48a DE-627 ger DE-627 rakwb eng Lubov I. Petrova verfasserin aut Chronic Triple Infection with Hepatitis B, C, and D Viruses in the Republic of Sakha (Yakutia) 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The purpose of this work was to study the features of the clinical course of mixed infections with hepatitis B+C+D viruses in the Republic of Sakha (Yakutia) (RS(Y)). Materials and Methods: The incidences of these infections were studied in the infectious disease department of the Yakutsk City Clinical Hospital. A total of 74 patients with chronic infection with hepatitis B, C, and D viruses were analyzed. The following markers of HBV (HBsAg, HBeAg, anti-HBcIgG, HBV DNA), HCV (anti-HCV) and HDV (anti-HDV, HDV RNA) were detected. According to PCR (n=35), HCV-RNA was detected in 29(82.8%) patients. In 65.8% of cases, HCV-RNA replication was observed in the absence of HDV-DNA. Mono-replication of HBV (HBV-DNA+, HCV-RNA-) was detected in 17.1% patients, mono-replication of HCV (HBV-DNA-, HCV-RNA+) in 65.7% patients and mixed replication of viruses C, D and/or G (HBV-DNA-, HCV-RNA+, HDV-RNA+/HGV-RNA+) in 17.1% patients. Results: The comparison of biochemical parameters of patients with chronic mixed hepatitis showed that more expressed changes are observed with the mixed replication than with the mono-replicative form of hepatitis. chronic mixed hepatitis hepatitis B virus hepatitis C virus hepatitis D virus Medicine R Snezhana S. Sleptsova verfasserin aut Maksim N. Andreev verfasserin aut Nikolai M. Gogolev verfasserin aut Anastasia N. Petrova verfasserin aut In International Journal of Biomedicine International Medical Research and Development Corporation, 2013 8(2018), 3, Seite 217-219 (DE-627)741171996 (DE-600)2710779-6 21580529 nnns volume:8 year:2018 number:3 pages:217-219 https://doi.org/10.21103/Article8(3)_OA9 kostenfrei https://doaj.org/article/57fec4d1b8e34e329ee514c55240e48a kostenfrei http://ijbm.org/articles/IJBM_8(3)_OA9.pdf kostenfrei https://doaj.org/toc/2158-0510 Journal toc kostenfrei https://doaj.org/toc/2158-0529 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2018 3 217-219 |
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Lubov I. Petrova |
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Chronic Triple Infection with Hepatitis B, C, and D Viruses in the Republic of Sakha (Yakutia) chronic mixed hepatitis hepatitis B virus hepatitis C virus hepatitis D virus |
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Chronic Triple Infection with Hepatitis B, C, and D Viruses in the Republic of Sakha (Yakutia) |
abstract |
The purpose of this work was to study the features of the clinical course of mixed infections with hepatitis B+C+D viruses in the Republic of Sakha (Yakutia) (RS(Y)). Materials and Methods: The incidences of these infections were studied in the infectious disease department of the Yakutsk City Clinical Hospital. A total of 74 patients with chronic infection with hepatitis B, C, and D viruses were analyzed. The following markers of HBV (HBsAg, HBeAg, anti-HBcIgG, HBV DNA), HCV (anti-HCV) and HDV (anti-HDV, HDV RNA) were detected. According to PCR (n=35), HCV-RNA was detected in 29(82.8%) patients. In 65.8% of cases, HCV-RNA replication was observed in the absence of HDV-DNA. Mono-replication of HBV (HBV-DNA+, HCV-RNA-) was detected in 17.1% patients, mono-replication of HCV (HBV-DNA-, HCV-RNA+) in 65.7% patients and mixed replication of viruses C, D and/or G (HBV-DNA-, HCV-RNA+, HDV-RNA+/HGV-RNA+) in 17.1% patients. Results: The comparison of biochemical parameters of patients with chronic mixed hepatitis showed that more expressed changes are observed with the mixed replication than with the mono-replicative form of hepatitis. |
abstractGer |
The purpose of this work was to study the features of the clinical course of mixed infections with hepatitis B+C+D viruses in the Republic of Sakha (Yakutia) (RS(Y)). Materials and Methods: The incidences of these infections were studied in the infectious disease department of the Yakutsk City Clinical Hospital. A total of 74 patients with chronic infection with hepatitis B, C, and D viruses were analyzed. The following markers of HBV (HBsAg, HBeAg, anti-HBcIgG, HBV DNA), HCV (anti-HCV) and HDV (anti-HDV, HDV RNA) were detected. According to PCR (n=35), HCV-RNA was detected in 29(82.8%) patients. In 65.8% of cases, HCV-RNA replication was observed in the absence of HDV-DNA. Mono-replication of HBV (HBV-DNA+, HCV-RNA-) was detected in 17.1% patients, mono-replication of HCV (HBV-DNA-, HCV-RNA+) in 65.7% patients and mixed replication of viruses C, D and/or G (HBV-DNA-, HCV-RNA+, HDV-RNA+/HGV-RNA+) in 17.1% patients. Results: The comparison of biochemical parameters of patients with chronic mixed hepatitis showed that more expressed changes are observed with the mixed replication than with the mono-replicative form of hepatitis. |
abstract_unstemmed |
The purpose of this work was to study the features of the clinical course of mixed infections with hepatitis B+C+D viruses in the Republic of Sakha (Yakutia) (RS(Y)). Materials and Methods: The incidences of these infections were studied in the infectious disease department of the Yakutsk City Clinical Hospital. A total of 74 patients with chronic infection with hepatitis B, C, and D viruses were analyzed. The following markers of HBV (HBsAg, HBeAg, anti-HBcIgG, HBV DNA), HCV (anti-HCV) and HDV (anti-HDV, HDV RNA) were detected. According to PCR (n=35), HCV-RNA was detected in 29(82.8%) patients. In 65.8% of cases, HCV-RNA replication was observed in the absence of HDV-DNA. Mono-replication of HBV (HBV-DNA+, HCV-RNA-) was detected in 17.1% patients, mono-replication of HCV (HBV-DNA-, HCV-RNA+) in 65.7% patients and mixed replication of viruses C, D and/or G (HBV-DNA-, HCV-RNA+, HDV-RNA+/HGV-RNA+) in 17.1% patients. Results: The comparison of biochemical parameters of patients with chronic mixed hepatitis showed that more expressed changes are observed with the mixed replication than with the mono-replicative form of hepatitis. |
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Chronic Triple Infection with Hepatitis B, C, and D Viruses in the Republic of Sakha (Yakutia) |
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