ETIOLOGICAL STUDY OF SEIZURES IN NEONATES

Objective: To determine the incidence and etiology of seizures among neonates admitted to Nursery unit of Hayatabad Medical Complex, Peshawar. Methodology: This descriptive study was conducted at Hayatabad Medical Complex, Peshawar, Pakistan from January to December 2011. During the study period, a...
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Autor*in:	Farid Ullah Shah [verfasserIn] Jehanzeb Khan [verfasserIn] Muhammad Aqeel Khan [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2013

Übergeordnetes Werk:	In: Khyber Medical University Journal - Khyber Medical University, 2018, 5(2013), 1, Seite 9-12
Übergeordnetes Werk:	volume:5 ; year:2013 ; number:1 ; pages:9-12

Links:	Link aufrufen Link aufrufen Journal toc Journal toc

Katalog-ID:	DOAJ001411098

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520			\|a Objective: To determine the incidence and etiology of seizures among neonates admitted to Nursery unit of Hayatabad Medical Complex, Peshawar. Methodology: This descriptive study was conducted at Hayatabad Medical Complex, Peshawar, Pakistan from January to December 2011. During the study period, all admitted neonatal cases were examined and data on neonatal seizures was ascertained. Among admitted neonates, having seizures either at presentation or during their stay in the hospital were investigated for its cause. Cases with clinical diagnosis of neonatal tetanus were excluded from the study. In order to determine the etiology of seizures, metabolic profile including blood glucose, serum calcium and sodium levels and other necessary tests were done in all cases. A proforma was designed comprising detailed history, general physical examination, systemic examination and relevant investigations. Data was recorded for analysis. Results: Seizures were observed in 159/1583 (9.95%) of neonatal admissions and 55.88% neonates had seizures during the first 72 hours of life. Commonest types of seizures observed in this study were subtle (39.6%) followed by tonic (31.4%), clonic (25.10%) and myoclonic (3.70%) seizures. Hypoxic ischemic encephalopathy was found to be the commonest cause (44%) of neonatal seizures, followed by hypoglycemia (18.8%) and hypocalcemia (12.5%). Casesof hypoxic ischemic encephalopathy were associated with higher mortality (42.85%) as compared to cases with metabolic seizures. Conclusion: Neonatal seizures were found in about 10% of neonatal admissions and presented most commonly as subtle type. Birth asphyxia was the commonest etiology of neonatal seizures, followed by the metabolic causes. Key words: Seizures, Etiology, Neonates, Birth Asphyxia, Hypoglycemia, Hypocalcemia.
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allfields	(DE-627)DOAJ001411098 (DE-599)DOAJ0306e34d899842dda55694fb263b506b DE-627 ger DE-627 rakwb eng Farid Ullah Shah verfasserin aut ETIOLOGICAL STUDY OF SEIZURES IN NEONATES 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To determine the incidence and etiology of seizures among neonates admitted to Nursery unit of Hayatabad Medical Complex, Peshawar. Methodology: This descriptive study was conducted at Hayatabad Medical Complex, Peshawar, Pakistan from January to December 2011. During the study period, all admitted neonatal cases were examined and data on neonatal seizures was ascertained. Among admitted neonates, having seizures either at presentation or during their stay in the hospital were investigated for its cause. Cases with clinical diagnosis of neonatal tetanus were excluded from the study. In order to determine the etiology of seizures, metabolic profile including blood glucose, serum calcium and sodium levels and other necessary tests were done in all cases. A proforma was designed comprising detailed history, general physical examination, systemic examination and relevant investigations. Data was recorded for analysis. Results: Seizures were observed in 159/1583 (9.95%) of neonatal admissions and 55.88% neonates had seizures during the first 72 hours of life. Commonest types of seizures observed in this study were subtle (39.6%) followed by tonic (31.4%), clonic (25.10%) and myoclonic (3.70%) seizures. Hypoxic ischemic encephalopathy was found to be the commonest cause (44%) of neonatal seizures, followed by hypoglycemia (18.8%) and hypocalcemia (12.5%). Casesof hypoxic ischemic encephalopathy were associated with higher mortality (42.85%) as compared to cases with metabolic seizures. Conclusion: Neonatal seizures were found in about 10% of neonatal admissions and presented most commonly as subtle type. Birth asphyxia was the commonest etiology of neonatal seizures, followed by the metabolic causes. Key words: Seizures, Etiology, Neonates, Birth Asphyxia, Hypoglycemia, Hypocalcemia. Medicine R Jehanzeb Khan verfasserin aut Muhammad Aqeel Khan verfasserin aut In Khyber Medical University Journal Khyber Medical University, 2018 5(2013), 1, Seite 9-12 (DE-627)739215868 (DE-600)2708145-X 23052651 nnns volume:5 year:2013 number:1 pages:9-12 https://doaj.org/article/0306e34d899842dda55694fb263b506b kostenfrei https://www.kmuj.kmu.edu.pk/article/view/11531 kostenfrei https://doaj.org/toc/2305-2643 Journal toc kostenfrei https://doaj.org/toc/2305-2651 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 5 2013 1 9-12
spelling	(DE-627)DOAJ001411098 (DE-599)DOAJ0306e34d899842dda55694fb263b506b DE-627 ger DE-627 rakwb eng Farid Ullah Shah verfasserin aut ETIOLOGICAL STUDY OF SEIZURES IN NEONATES 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To determine the incidence and etiology of seizures among neonates admitted to Nursery unit of Hayatabad Medical Complex, Peshawar. Methodology: This descriptive study was conducted at Hayatabad Medical Complex, Peshawar, Pakistan from January to December 2011. During the study period, all admitted neonatal cases were examined and data on neonatal seizures was ascertained. Among admitted neonates, having seizures either at presentation or during their stay in the hospital were investigated for its cause. Cases with clinical diagnosis of neonatal tetanus were excluded from the study. In order to determine the etiology of seizures, metabolic profile including blood glucose, serum calcium and sodium levels and other necessary tests were done in all cases. A proforma was designed comprising detailed history, general physical examination, systemic examination and relevant investigations. Data was recorded for analysis. Results: Seizures were observed in 159/1583 (9.95%) of neonatal admissions and 55.88% neonates had seizures during the first 72 hours of life. Commonest types of seizures observed in this study were subtle (39.6%) followed by tonic (31.4%), clonic (25.10%) and myoclonic (3.70%) seizures. Hypoxic ischemic encephalopathy was found to be the commonest cause (44%) of neonatal seizures, followed by hypoglycemia (18.8%) and hypocalcemia (12.5%). Casesof hypoxic ischemic encephalopathy were associated with higher mortality (42.85%) as compared to cases with metabolic seizures. Conclusion: Neonatal seizures were found in about 10% of neonatal admissions and presented most commonly as subtle type. Birth asphyxia was the commonest etiology of neonatal seizures, followed by the metabolic causes. Key words: Seizures, Etiology, Neonates, Birth Asphyxia, Hypoglycemia, Hypocalcemia. Medicine R Jehanzeb Khan verfasserin aut Muhammad Aqeel Khan verfasserin aut In Khyber Medical University Journal Khyber Medical University, 2018 5(2013), 1, Seite 9-12 (DE-627)739215868 (DE-600)2708145-X 23052651 nnns volume:5 year:2013 number:1 pages:9-12 https://doaj.org/article/0306e34d899842dda55694fb263b506b kostenfrei https://www.kmuj.kmu.edu.pk/article/view/11531 kostenfrei https://doaj.org/toc/2305-2643 Journal toc kostenfrei https://doaj.org/toc/2305-2651 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 5 2013 1 9-12
allfields_unstemmed	(DE-627)DOAJ001411098 (DE-599)DOAJ0306e34d899842dda55694fb263b506b DE-627 ger DE-627 rakwb eng Farid Ullah Shah verfasserin aut ETIOLOGICAL STUDY OF SEIZURES IN NEONATES 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To determine the incidence and etiology of seizures among neonates admitted to Nursery unit of Hayatabad Medical Complex, Peshawar. Methodology: This descriptive study was conducted at Hayatabad Medical Complex, Peshawar, Pakistan from January to December 2011. During the study period, all admitted neonatal cases were examined and data on neonatal seizures was ascertained. Among admitted neonates, having seizures either at presentation or during their stay in the hospital were investigated for its cause. Cases with clinical diagnosis of neonatal tetanus were excluded from the study. In order to determine the etiology of seizures, metabolic profile including blood glucose, serum calcium and sodium levels and other necessary tests were done in all cases. A proforma was designed comprising detailed history, general physical examination, systemic examination and relevant investigations. Data was recorded for analysis. Results: Seizures were observed in 159/1583 (9.95%) of neonatal admissions and 55.88% neonates had seizures during the first 72 hours of life. Commonest types of seizures observed in this study were subtle (39.6%) followed by tonic (31.4%), clonic (25.10%) and myoclonic (3.70%) seizures. Hypoxic ischemic encephalopathy was found to be the commonest cause (44%) of neonatal seizures, followed by hypoglycemia (18.8%) and hypocalcemia (12.5%). Casesof hypoxic ischemic encephalopathy were associated with higher mortality (42.85%) as compared to cases with metabolic seizures. Conclusion: Neonatal seizures were found in about 10% of neonatal admissions and presented most commonly as subtle type. Birth asphyxia was the commonest etiology of neonatal seizures, followed by the metabolic causes. Key words: Seizures, Etiology, Neonates, Birth Asphyxia, Hypoglycemia, Hypocalcemia. Medicine R Jehanzeb Khan verfasserin aut Muhammad Aqeel Khan verfasserin aut In Khyber Medical University Journal Khyber Medical University, 2018 5(2013), 1, Seite 9-12 (DE-627)739215868 (DE-600)2708145-X 23052651 nnns volume:5 year:2013 number:1 pages:9-12 https://doaj.org/article/0306e34d899842dda55694fb263b506b kostenfrei https://www.kmuj.kmu.edu.pk/article/view/11531 kostenfrei https://doaj.org/toc/2305-2643 Journal toc kostenfrei https://doaj.org/toc/2305-2651 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 5 2013 1 9-12
allfieldsGer	(DE-627)DOAJ001411098 (DE-599)DOAJ0306e34d899842dda55694fb263b506b DE-627 ger DE-627 rakwb eng Farid Ullah Shah verfasserin aut ETIOLOGICAL STUDY OF SEIZURES IN NEONATES 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To determine the incidence and etiology of seizures among neonates admitted to Nursery unit of Hayatabad Medical Complex, Peshawar. Methodology: This descriptive study was conducted at Hayatabad Medical Complex, Peshawar, Pakistan from January to December 2011. During the study period, all admitted neonatal cases were examined and data on neonatal seizures was ascertained. Among admitted neonates, having seizures either at presentation or during their stay in the hospital were investigated for its cause. Cases with clinical diagnosis of neonatal tetanus were excluded from the study. In order to determine the etiology of seizures, metabolic profile including blood glucose, serum calcium and sodium levels and other necessary tests were done in all cases. A proforma was designed comprising detailed history, general physical examination, systemic examination and relevant investigations. Data was recorded for analysis. Results: Seizures were observed in 159/1583 (9.95%) of neonatal admissions and 55.88% neonates had seizures during the first 72 hours of life. Commonest types of seizures observed in this study were subtle (39.6%) followed by tonic (31.4%), clonic (25.10%) and myoclonic (3.70%) seizures. Hypoxic ischemic encephalopathy was found to be the commonest cause (44%) of neonatal seizures, followed by hypoglycemia (18.8%) and hypocalcemia (12.5%). Casesof hypoxic ischemic encephalopathy were associated with higher mortality (42.85%) as compared to cases with metabolic seizures. Conclusion: Neonatal seizures were found in about 10% of neonatal admissions and presented most commonly as subtle type. Birth asphyxia was the commonest etiology of neonatal seizures, followed by the metabolic causes. Key words: Seizures, Etiology, Neonates, Birth Asphyxia, Hypoglycemia, Hypocalcemia. Medicine R Jehanzeb Khan verfasserin aut Muhammad Aqeel Khan verfasserin aut In Khyber Medical University Journal Khyber Medical University, 2018 5(2013), 1, Seite 9-12 (DE-627)739215868 (DE-600)2708145-X 23052651 nnns volume:5 year:2013 number:1 pages:9-12 https://doaj.org/article/0306e34d899842dda55694fb263b506b kostenfrei https://www.kmuj.kmu.edu.pk/article/view/11531 kostenfrei https://doaj.org/toc/2305-2643 Journal toc kostenfrei https://doaj.org/toc/2305-2651 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 5 2013 1 9-12
allfieldsSound	(DE-627)DOAJ001411098 (DE-599)DOAJ0306e34d899842dda55694fb263b506b DE-627 ger DE-627 rakwb eng Farid Ullah Shah verfasserin aut ETIOLOGICAL STUDY OF SEIZURES IN NEONATES 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: To determine the incidence and etiology of seizures among neonates admitted to Nursery unit of Hayatabad Medical Complex, Peshawar. Methodology: This descriptive study was conducted at Hayatabad Medical Complex, Peshawar, Pakistan from January to December 2011. During the study period, all admitted neonatal cases were examined and data on neonatal seizures was ascertained. Among admitted neonates, having seizures either at presentation or during their stay in the hospital were investigated for its cause. Cases with clinical diagnosis of neonatal tetanus were excluded from the study. In order to determine the etiology of seizures, metabolic profile including blood glucose, serum calcium and sodium levels and other necessary tests were done in all cases. A proforma was designed comprising detailed history, general physical examination, systemic examination and relevant investigations. Data was recorded for analysis. Results: Seizures were observed in 159/1583 (9.95%) of neonatal admissions and 55.88% neonates had seizures during the first 72 hours of life. Commonest types of seizures observed in this study were subtle (39.6%) followed by tonic (31.4%), clonic (25.10%) and myoclonic (3.70%) seizures. Hypoxic ischemic encephalopathy was found to be the commonest cause (44%) of neonatal seizures, followed by hypoglycemia (18.8%) and hypocalcemia (12.5%). Casesof hypoxic ischemic encephalopathy were associated with higher mortality (42.85%) as compared to cases with metabolic seizures. Conclusion: Neonatal seizures were found in about 10% of neonatal admissions and presented most commonly as subtle type. Birth asphyxia was the commonest etiology of neonatal seizures, followed by the metabolic causes. Key words: Seizures, Etiology, Neonates, Birth Asphyxia, Hypoglycemia, Hypocalcemia. Medicine R Jehanzeb Khan verfasserin aut Muhammad Aqeel Khan verfasserin aut In Khyber Medical University Journal Khyber Medical University, 2018 5(2013), 1, Seite 9-12 (DE-627)739215868 (DE-600)2708145-X 23052651 nnns volume:5 year:2013 number:1 pages:9-12 https://doaj.org/article/0306e34d899842dda55694fb263b506b kostenfrei https://www.kmuj.kmu.edu.pk/article/view/11531 kostenfrei https://doaj.org/toc/2305-2643 Journal toc kostenfrei https://doaj.org/toc/2305-2651 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 5 2013 1 9-12
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Commonest types of seizures observed in this study were subtle (39.6%) followed by tonic (31.4%), clonic (25.10%) and myoclonic (3.70%) seizures. Hypoxic ischemic encephalopathy was found to be the commonest cause (44%) of neonatal seizures, followed by hypoglycemia (18.8%) and hypocalcemia (12.5%). Casesof hypoxic ischemic encephalopathy were associated with higher mortality (42.85%) as compared to cases with metabolic seizures. Conclusion: Neonatal seizures were found in about 10% of neonatal admissions and presented most commonly as subtle type. Birth asphyxia was the commonest etiology of neonatal seizures, followed by the metabolic causes. 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author	Farid Ullah Shah
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title	ETIOLOGICAL STUDY OF SEIZURES IN NEONATES
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author_browse	Farid Ullah Shah Jehanzeb Khan Muhammad Aqeel Khan
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title_sort	etiological study of seizures in neonates
title_auth	ETIOLOGICAL STUDY OF SEIZURES IN NEONATES
abstract	Objective: To determine the incidence and etiology of seizures among neonates admitted to Nursery unit of Hayatabad Medical Complex, Peshawar. Methodology: This descriptive study was conducted at Hayatabad Medical Complex, Peshawar, Pakistan from January to December 2011. During the study period, all admitted neonatal cases were examined and data on neonatal seizures was ascertained. Among admitted neonates, having seizures either at presentation or during their stay in the hospital were investigated for its cause. Cases with clinical diagnosis of neonatal tetanus were excluded from the study. In order to determine the etiology of seizures, metabolic profile including blood glucose, serum calcium and sodium levels and other necessary tests were done in all cases. A proforma was designed comprising detailed history, general physical examination, systemic examination and relevant investigations. Data was recorded for analysis. Results: Seizures were observed in 159/1583 (9.95%) of neonatal admissions and 55.88% neonates had seizures during the first 72 hours of life. Commonest types of seizures observed in this study were subtle (39.6%) followed by tonic (31.4%), clonic (25.10%) and myoclonic (3.70%) seizures. Hypoxic ischemic encephalopathy was found to be the commonest cause (44%) of neonatal seizures, followed by hypoglycemia (18.8%) and hypocalcemia (12.5%). Casesof hypoxic ischemic encephalopathy were associated with higher mortality (42.85%) as compared to cases with metabolic seizures. Conclusion: Neonatal seizures were found in about 10% of neonatal admissions and presented most commonly as subtle type. Birth asphyxia was the commonest etiology of neonatal seizures, followed by the metabolic causes. Key words: Seizures, Etiology, Neonates, Birth Asphyxia, Hypoglycemia, Hypocalcemia.
abstractGer	Objective: To determine the incidence and etiology of seizures among neonates admitted to Nursery unit of Hayatabad Medical Complex, Peshawar. Methodology: This descriptive study was conducted at Hayatabad Medical Complex, Peshawar, Pakistan from January to December 2011. During the study period, all admitted neonatal cases were examined and data on neonatal seizures was ascertained. Among admitted neonates, having seizures either at presentation or during their stay in the hospital were investigated for its cause. Cases with clinical diagnosis of neonatal tetanus were excluded from the study. In order to determine the etiology of seizures, metabolic profile including blood glucose, serum calcium and sodium levels and other necessary tests were done in all cases. A proforma was designed comprising detailed history, general physical examination, systemic examination and relevant investigations. Data was recorded for analysis. Results: Seizures were observed in 159/1583 (9.95%) of neonatal admissions and 55.88% neonates had seizures during the first 72 hours of life. Commonest types of seizures observed in this study were subtle (39.6%) followed by tonic (31.4%), clonic (25.10%) and myoclonic (3.70%) seizures. Hypoxic ischemic encephalopathy was found to be the commonest cause (44%) of neonatal seizures, followed by hypoglycemia (18.8%) and hypocalcemia (12.5%). Casesof hypoxic ischemic encephalopathy were associated with higher mortality (42.85%) as compared to cases with metabolic seizures. Conclusion: Neonatal seizures were found in about 10% of neonatal admissions and presented most commonly as subtle type. Birth asphyxia was the commonest etiology of neonatal seizures, followed by the metabolic causes. Key words: Seizures, Etiology, Neonates, Birth Asphyxia, Hypoglycemia, Hypocalcemia.
abstract_unstemmed	Objective: To determine the incidence and etiology of seizures among neonates admitted to Nursery unit of Hayatabad Medical Complex, Peshawar. Methodology: This descriptive study was conducted at Hayatabad Medical Complex, Peshawar, Pakistan from January to December 2011. During the study period, all admitted neonatal cases were examined and data on neonatal seizures was ascertained. Among admitted neonates, having seizures either at presentation or during their stay in the hospital were investigated for its cause. Cases with clinical diagnosis of neonatal tetanus were excluded from the study. In order to determine the etiology of seizures, metabolic profile including blood glucose, serum calcium and sodium levels and other necessary tests were done in all cases. A proforma was designed comprising detailed history, general physical examination, systemic examination and relevant investigations. Data was recorded for analysis. Results: Seizures were observed in 159/1583 (9.95%) of neonatal admissions and 55.88% neonates had seizures during the first 72 hours of life. Commonest types of seizures observed in this study were subtle (39.6%) followed by tonic (31.4%), clonic (25.10%) and myoclonic (3.70%) seizures. Hypoxic ischemic encephalopathy was found to be the commonest cause (44%) of neonatal seizures, followed by hypoglycemia (18.8%) and hypocalcemia (12.5%). Casesof hypoxic ischemic encephalopathy were associated with higher mortality (42.85%) as compared to cases with metabolic seizures. Conclusion: Neonatal seizures were found in about 10% of neonatal admissions and presented most commonly as subtle type. Birth asphyxia was the commonest etiology of neonatal seizures, followed by the metabolic causes. Key words: Seizures, Etiology, Neonates, Birth Asphyxia, Hypoglycemia, Hypocalcemia.
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title_short	ETIOLOGICAL STUDY OF SEIZURES IN NEONATES
url	https://doaj.org/article/0306e34d899842dda55694fb263b506b https://www.kmuj.kmu.edu.pk/article/view/11531 https://doaj.org/toc/2305-2643 https://doaj.org/toc/2305-2651
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