Evaluation and Interpretation of AMH in Female Infertility
Anti-Müllerian hormone (AMH) is a glycoprotein that secreted by the granulosa cells of the pre-antral and antral ovarian follicles that have a diameter <8 mm. By inhibiting both initial recruitments of primordial follicles into primary follicles and also the sensitivity of antral follicles to...
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| Autor*in: |
Şule Atalay Mert [verfasserIn] Berna Dilbaz [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2022 |
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In: Düzce Tıp Fakültesi Dergisi - Duzce University, 2009, 24(2022), Special Issue, Seite 82-85 |
|---|---|
| Übergeordnetes Werk: |
volume:24 ; year:2022 ; number:Special Issue ; pages:82-85 |
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|---|
| DOI / URN: |
10.18678/dtfd.1186131 |
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DOAJ002165430 |
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| 520 | |a Anti-Müllerian hormone (AMH) is a glycoprotein that secreted by the granulosa cells of the pre-antral and antral ovarian follicles that have a diameter <8 mm. By inhibiting both initial recruitments of primordial follicles into primary follicles and also the sensitivity of antral follicles to follicle stimulating hormone (FSH) in cyclic recruitment AMH acts as a “follicular gatekeeper”. AMH is recognized as an early marker of the decline in the follicular pool. Although AMH levels are accepted to be stable all through the menstrual cycle, inter- and intracycle variability are detected in the studies with the highly sensitive automated assays. Besides aging, body mass index, obesity, oral contraceptive use, previous ovarian surgery, chemotherapy, BRCA mutations, and ethnicity play a role on the AMH levels. Polycystic ovary syndrome (PCOS) is related with increased AMH level and thus proposed to be used as a diagnostic criterion. However, there is no universally accepted threshold value for AMH that can be used in the diagnosis of PCOS. AMH levels have also been used for designing an ideal treatment protocol in assisted reproduction. AMH measurements can be utilized for the prediction of poor or hyper ovarian response. The value of AMH levels in the prediction of pregnancy outcome remains controversial. | ||
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10.18678/dtfd.1186131 doi (DE-627)DOAJ002165430 (DE-599)DOAJaa5ca770a6c3477e908e493e09b14cb8 DE-627 ger DE-627 rakwb eng R5-920 Şule Atalay Mert verfasserin aut Evaluation and Interpretation of AMH in Female Infertility 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Anti-Müllerian hormone (AMH) is a glycoprotein that secreted by the granulosa cells of the pre-antral and antral ovarian follicles that have a diameter <8 mm. By inhibiting both initial recruitments of primordial follicles into primary follicles and also the sensitivity of antral follicles to follicle stimulating hormone (FSH) in cyclic recruitment AMH acts as a “follicular gatekeeper”. AMH is recognized as an early marker of the decline in the follicular pool. Although AMH levels are accepted to be stable all through the menstrual cycle, inter- and intracycle variability are detected in the studies with the highly sensitive automated assays. Besides aging, body mass index, obesity, oral contraceptive use, previous ovarian surgery, chemotherapy, BRCA mutations, and ethnicity play a role on the AMH levels. Polycystic ovary syndrome (PCOS) is related with increased AMH level and thus proposed to be used as a diagnostic criterion. However, there is no universally accepted threshold value for AMH that can be used in the diagnosis of PCOS. AMH levels have also been used for designing an ideal treatment protocol in assisted reproduction. AMH measurements can be utilized for the prediction of poor or hyper ovarian response. The value of AMH levels in the prediction of pregnancy outcome remains controversial. anti-müllerian hormone female infertility anti-müllerian hormon kadın infertilite Medicine R Medicine (General) Berna Dilbaz verfasserin aut In Düzce Tıp Fakültesi Dergisi Duzce University, 2009 24(2022), Special Issue, Seite 82-85 (DE-627)1760599271 (DE-600)3068837-1 1307671X nnns volume:24 year:2022 number:Special Issue pages:82-85 https://doi.org/10.18678/dtfd.1186131 kostenfrei https://doaj.org/article/aa5ca770a6c3477e908e493e09b14cb8 kostenfrei https://dergipark.org.tr/en/download/article-file/2696497 kostenfrei https://doaj.org/toc/1307-671X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 24 2022 Special Issue 82-85 |
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10.18678/dtfd.1186131 doi (DE-627)DOAJ002165430 (DE-599)DOAJaa5ca770a6c3477e908e493e09b14cb8 DE-627 ger DE-627 rakwb eng R5-920 Şule Atalay Mert verfasserin aut Evaluation and Interpretation of AMH in Female Infertility 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Anti-Müllerian hormone (AMH) is a glycoprotein that secreted by the granulosa cells of the pre-antral and antral ovarian follicles that have a diameter <8 mm. By inhibiting both initial recruitments of primordial follicles into primary follicles and also the sensitivity of antral follicles to follicle stimulating hormone (FSH) in cyclic recruitment AMH acts as a “follicular gatekeeper”. AMH is recognized as an early marker of the decline in the follicular pool. Although AMH levels are accepted to be stable all through the menstrual cycle, inter- and intracycle variability are detected in the studies with the highly sensitive automated assays. Besides aging, body mass index, obesity, oral contraceptive use, previous ovarian surgery, chemotherapy, BRCA mutations, and ethnicity play a role on the AMH levels. Polycystic ovary syndrome (PCOS) is related with increased AMH level and thus proposed to be used as a diagnostic criterion. However, there is no universally accepted threshold value for AMH that can be used in the diagnosis of PCOS. AMH levels have also been used for designing an ideal treatment protocol in assisted reproduction. AMH measurements can be utilized for the prediction of poor or hyper ovarian response. The value of AMH levels in the prediction of pregnancy outcome remains controversial. anti-müllerian hormone female infertility anti-müllerian hormon kadın infertilite Medicine R Medicine (General) Berna Dilbaz verfasserin aut In Düzce Tıp Fakültesi Dergisi Duzce University, 2009 24(2022), Special Issue, Seite 82-85 (DE-627)1760599271 (DE-600)3068837-1 1307671X nnns volume:24 year:2022 number:Special Issue pages:82-85 https://doi.org/10.18678/dtfd.1186131 kostenfrei https://doaj.org/article/aa5ca770a6c3477e908e493e09b14cb8 kostenfrei https://dergipark.org.tr/en/download/article-file/2696497 kostenfrei https://doaj.org/toc/1307-671X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 24 2022 Special Issue 82-85 |
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Evaluation and Interpretation of AMH in Female Infertility |
| abstract |
Anti-Müllerian hormone (AMH) is a glycoprotein that secreted by the granulosa cells of the pre-antral and antral ovarian follicles that have a diameter <8 mm. By inhibiting both initial recruitments of primordial follicles into primary follicles and also the sensitivity of antral follicles to follicle stimulating hormone (FSH) in cyclic recruitment AMH acts as a “follicular gatekeeper”. AMH is recognized as an early marker of the decline in the follicular pool. Although AMH levels are accepted to be stable all through the menstrual cycle, inter- and intracycle variability are detected in the studies with the highly sensitive automated assays. Besides aging, body mass index, obesity, oral contraceptive use, previous ovarian surgery, chemotherapy, BRCA mutations, and ethnicity play a role on the AMH levels. Polycystic ovary syndrome (PCOS) is related with increased AMH level and thus proposed to be used as a diagnostic criterion. However, there is no universally accepted threshold value for AMH that can be used in the diagnosis of PCOS. AMH levels have also been used for designing an ideal treatment protocol in assisted reproduction. AMH measurements can be utilized for the prediction of poor or hyper ovarian response. The value of AMH levels in the prediction of pregnancy outcome remains controversial. |
| abstractGer |
Anti-Müllerian hormone (AMH) is a glycoprotein that secreted by the granulosa cells of the pre-antral and antral ovarian follicles that have a diameter <8 mm. By inhibiting both initial recruitments of primordial follicles into primary follicles and also the sensitivity of antral follicles to follicle stimulating hormone (FSH) in cyclic recruitment AMH acts as a “follicular gatekeeper”. AMH is recognized as an early marker of the decline in the follicular pool. Although AMH levels are accepted to be stable all through the menstrual cycle, inter- and intracycle variability are detected in the studies with the highly sensitive automated assays. Besides aging, body mass index, obesity, oral contraceptive use, previous ovarian surgery, chemotherapy, BRCA mutations, and ethnicity play a role on the AMH levels. Polycystic ovary syndrome (PCOS) is related with increased AMH level and thus proposed to be used as a diagnostic criterion. However, there is no universally accepted threshold value for AMH that can be used in the diagnosis of PCOS. AMH levels have also been used for designing an ideal treatment protocol in assisted reproduction. AMH measurements can be utilized for the prediction of poor or hyper ovarian response. The value of AMH levels in the prediction of pregnancy outcome remains controversial. |
| abstract_unstemmed |
Anti-Müllerian hormone (AMH) is a glycoprotein that secreted by the granulosa cells of the pre-antral and antral ovarian follicles that have a diameter <8 mm. By inhibiting both initial recruitments of primordial follicles into primary follicles and also the sensitivity of antral follicles to follicle stimulating hormone (FSH) in cyclic recruitment AMH acts as a “follicular gatekeeper”. AMH is recognized as an early marker of the decline in the follicular pool. Although AMH levels are accepted to be stable all through the menstrual cycle, inter- and intracycle variability are detected in the studies with the highly sensitive automated assays. Besides aging, body mass index, obesity, oral contraceptive use, previous ovarian surgery, chemotherapy, BRCA mutations, and ethnicity play a role on the AMH levels. Polycystic ovary syndrome (PCOS) is related with increased AMH level and thus proposed to be used as a diagnostic criterion. However, there is no universally accepted threshold value for AMH that can be used in the diagnosis of PCOS. AMH levels have also been used for designing an ideal treatment protocol in assisted reproduction. AMH measurements can be utilized for the prediction of poor or hyper ovarian response. The value of AMH levels in the prediction of pregnancy outcome remains controversial. |
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Special Issue |
| title_short |
Evaluation and Interpretation of AMH in Female Infertility |
| url |
https://doi.org/10.18678/dtfd.1186131 https://doaj.org/article/aa5ca770a6c3477e908e493e09b14cb8 https://dergipark.org.tr/en/download/article-file/2696497 https://doaj.org/toc/1307-671X |
| remote_bool |
true |
| author2 |
Berna Dilbaz |
| author2Str |
Berna Dilbaz |
| ppnlink |
1760599271 |
| callnumber-subject |
R - General Medicine |
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c |
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false |
| doi_str |
10.18678/dtfd.1186131 |
| callnumber-a |
R5-920 |
| up_date |
2024-07-04T00:08:57.160Z |
| _version_ |
1803604970347429888 |
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| score |
7.401991 |