Stereotactic Arrhythmia Radioablation as a Novel Treatment Approach for Cardiac Arrhythmias: Facts and Limitations

Stereotactic ablative radiotherapy (SABR) is highly focused radiation therapy that targets well-demarcated, limited-volume malignant or benign tumors with high accuracy and precision using image guidance. Stereotactic arrhythmia radioablation (STAR) applies SABR to treat cardiac arrhythmias, includi...
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Gespeichert in:

Autor*in:	Marina Chalkia [verfasserIn] Vassilis Kouloulias [verfasserIn] Dimitris Tousoulis [verfasserIn] Spyridon Deftereos [verfasserIn] Dimitris Tsiachris [verfasserIn] Dimitrios Vrachatis [verfasserIn] Kalliopi Platoni [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	ventricular tachycardia atrial fibrillation cardiac arrhythmias radioablation stereotactic radiotherapy stereotactic body radiation therapy

Übergeordnetes Werk:	In: Biomedicines - MDPI AG, 2014, 9(2021), 10, p 1461
Übergeordnetes Werk:	volume:9 ; year:2021 ; number:10, p 1461

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/biomedicines9101461

Katalog-ID:	DOAJ003869180

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allfieldsSound	10.3390/biomedicines9101461 doi (DE-627)DOAJ003869180 (DE-599)DOAJ6e7442cd403c4caa9c1af62dd9157c06 DE-627 ger DE-627 rakwb eng QH301-705.5 Marina Chalkia verfasserin aut Stereotactic Arrhythmia Radioablation as a Novel Treatment Approach for Cardiac Arrhythmias: Facts and Limitations 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Stereotactic ablative radiotherapy (SABR) is highly focused radiation therapy that targets well-demarcated, limited-volume malignant or benign tumors with high accuracy and precision using image guidance. Stereotactic arrhythmia radioablation (STAR) applies SABR to treat cardiac arrhythmias, including ventricular tachycardia (VT) and atrial fibrillation (AF), and has recently been a focus in research. Clinical studies have demonstrated electrophysiologic conduction blockade and histologic fibrosis after STAR, which provides a proof of principle for its potential for treating arrhythmias. This review will present the basic STAR principles, available clinical study outcomes, and how the technique has evolved since the first pre-clinical study. In addition to the clinical workflow, focus will be given on the process for stereotactic radiotherapy Quality Assurance (QA) tests, as well as the need for establishing a standardized QA protocol. Future implications and potential courses of research will also be discussed. ventricular tachycardia atrial fibrillation cardiac arrhythmias radioablation stereotactic radiotherapy stereotactic body radiation therapy Biology (General) Vassilis Kouloulias verfasserin aut Dimitris Tousoulis verfasserin aut Spyridon Deftereos verfasserin aut Dimitris Tsiachris verfasserin aut Dimitrios Vrachatis verfasserin aut Kalliopi Platoni verfasserin aut In Biomedicines MDPI AG, 2014 9(2021), 10, p 1461 (DE-627)750370483 (DE-600)2720867-9 22279059 nnns volume:9 year:2021 number:10, p 1461 https://doi.org/10.3390/biomedicines9101461 kostenfrei https://doaj.org/article/6e7442cd403c4caa9c1af62dd9157c06 kostenfrei https://www.mdpi.com/2227-9059/9/10/1461 kostenfrei https://doaj.org/toc/2227-9059 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2021 10, p 1461
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source	In Biomedicines 9(2021), 10, p 1461 volume:9 year:2021 number:10, p 1461
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topic_facet	ventricular tachycardia atrial fibrillation cardiac arrhythmias radioablation stereotactic radiotherapy stereotactic body radiation therapy Biology (General)
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authorswithroles_txt_mv	Marina Chalkia @@aut@@ Vassilis Kouloulias @@aut@@ Dimitris Tousoulis @@aut@@ Spyridon Deftereos @@aut@@ Dimitris Tsiachris @@aut@@ Dimitrios Vrachatis @@aut@@ Kalliopi Platoni @@aut@@
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author	Marina Chalkia
spellingShingle	Marina Chalkia misc QH301-705.5 misc ventricular tachycardia misc atrial fibrillation misc cardiac arrhythmias misc radioablation misc stereotactic radiotherapy misc stereotactic body radiation therapy misc Biology (General) Stereotactic Arrhythmia Radioablation as a Novel Treatment Approach for Cardiac Arrhythmias: Facts and Limitations
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topic_title	QH301-705.5 Stereotactic Arrhythmia Radioablation as a Novel Treatment Approach for Cardiac Arrhythmias: Facts and Limitations ventricular tachycardia atrial fibrillation cardiac arrhythmias radioablation stereotactic radiotherapy stereotactic body radiation therapy
topic	misc QH301-705.5 misc ventricular tachycardia misc atrial fibrillation misc cardiac arrhythmias misc radioablation misc stereotactic radiotherapy misc stereotactic body radiation therapy misc Biology (General)
topic_unstemmed	misc QH301-705.5 misc ventricular tachycardia misc atrial fibrillation misc cardiac arrhythmias misc radioablation misc stereotactic radiotherapy misc stereotactic body radiation therapy misc Biology (General)
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title	Stereotactic Arrhythmia Radioablation as a Novel Treatment Approach for Cardiac Arrhythmias: Facts and Limitations
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title_sort	stereotactic arrhythmia radioablation as a novel treatment approach for cardiac arrhythmias: facts and limitations
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title_auth	Stereotactic Arrhythmia Radioablation as a Novel Treatment Approach for Cardiac Arrhythmias: Facts and Limitations
abstract	Stereotactic ablative radiotherapy (SABR) is highly focused radiation therapy that targets well-demarcated, limited-volume malignant or benign tumors with high accuracy and precision using image guidance. Stereotactic arrhythmia radioablation (STAR) applies SABR to treat cardiac arrhythmias, including ventricular tachycardia (VT) and atrial fibrillation (AF), and has recently been a focus in research. Clinical studies have demonstrated electrophysiologic conduction blockade and histologic fibrosis after STAR, which provides a proof of principle for its potential for treating arrhythmias. This review will present the basic STAR principles, available clinical study outcomes, and how the technique has evolved since the first pre-clinical study. In addition to the clinical workflow, focus will be given on the process for stereotactic radiotherapy Quality Assurance (QA) tests, as well as the need for establishing a standardized QA protocol. Future implications and potential courses of research will also be discussed.
abstractGer	Stereotactic ablative radiotherapy (SABR) is highly focused radiation therapy that targets well-demarcated, limited-volume malignant or benign tumors with high accuracy and precision using image guidance. Stereotactic arrhythmia radioablation (STAR) applies SABR to treat cardiac arrhythmias, including ventricular tachycardia (VT) and atrial fibrillation (AF), and has recently been a focus in research. Clinical studies have demonstrated electrophysiologic conduction blockade and histologic fibrosis after STAR, which provides a proof of principle for its potential for treating arrhythmias. This review will present the basic STAR principles, available clinical study outcomes, and how the technique has evolved since the first pre-clinical study. In addition to the clinical workflow, focus will be given on the process for stereotactic radiotherapy Quality Assurance (QA) tests, as well as the need for establishing a standardized QA protocol. Future implications and potential courses of research will also be discussed.
abstract_unstemmed	Stereotactic ablative radiotherapy (SABR) is highly focused radiation therapy that targets well-demarcated, limited-volume malignant or benign tumors with high accuracy and precision using image guidance. Stereotactic arrhythmia radioablation (STAR) applies SABR to treat cardiac arrhythmias, including ventricular tachycardia (VT) and atrial fibrillation (AF), and has recently been a focus in research. Clinical studies have demonstrated electrophysiologic conduction blockade and histologic fibrosis after STAR, which provides a proof of principle for its potential for treating arrhythmias. This review will present the basic STAR principles, available clinical study outcomes, and how the technique has evolved since the first pre-clinical study. In addition to the clinical workflow, focus will be given on the process for stereotactic radiotherapy Quality Assurance (QA) tests, as well as the need for establishing a standardized QA protocol. Future implications and potential courses of research will also be discussed.
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title_short	Stereotactic Arrhythmia Radioablation as a Novel Treatment Approach for Cardiac Arrhythmias: Facts and Limitations
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