Safety and efficacy of ROVABIO® SPIKY (endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase) as a feed additive for all major and minor poultry species

Abstract ROVABIO® SPIKY is a preparation of endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase that is authorised as a feed additive for chickens and turkeys for fattening, chickens reared for laying, turkeys reared for breeding, minor poultry species for fattening and reared for laying. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP Panel) issued two opinions on this additive. Safety aspects regarding the use of this additive in feed have been previously established. The Panel concluded that the additive is safe for the consumers and the environment and that the additive is not irritant to the skin or eyes but should be considered a potential skin sensitiser and potentially harmful if inhaled. The Panel considered that these conclusions are still valid for the current application. The current application covered the use of the additive in all poultry species at the dose of 1,100 U xylanase and 760 U glucanase per kg feed. In previous assessments, the Panel concluded that the additive is safe and efficacious under the proposed conditions of use in chickens and turkeys for fattening or raised for laying/breeding and to minor poultry species for fattening or raised for laying/breeding. In order to support the safety for laying animals, the applicant provided a tolerance trial in laying hens from which the Panel concluded that the additive is safe for laying hens at the recommended dose. The safety established in laying hens is considered to apply also to breeding hens and can be extrapolated to minor poultry species for laying. Regarding the efficacy the additive increased the metabolisable energy content of the diets in one trial and the performance of the laying hens in two trials at the recommended dose. Therefore, the FEEDAP Panel concluded that the additive has the potential to be efficacious in laying hens. This conclusion applies also to breeding hens and can be extrapolated to include all minor poultry species for laying. Ausführliche Beschreibung

Gespeichert in:

Autor*in:	EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2016

Schlagwörter:	zootechnical additive digestibility enhancers endo‐1,4‐beta‐xylanase endo‐1,3(4)‐beta‐glucanase, poultry

Übergeordnetes Werk:	In: EFSA Journal - Wiley, 2018, 14(2016), 6, Seite n/a-n/a
Übergeordnetes Werk:	volume:14 ; year:2016 ; number:6 ; pages:n/a-n/a

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.2903/j.efsa.2016.4510

Katalog-ID:	DOAJ004312015

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allfields	10.2903/j.efsa.2016.4510 doi (DE-627)DOAJ004312015 (DE-599)DOAJ819f7e365f474289bee7bbb172c6b943 DE-627 ger DE-627 rakwb eng TX341-641 TP1-1185 EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) verfasserin aut Safety and efficacy of ROVABIO® SPIKY (endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase) as a feed additive for all major and minor poultry species 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract ROVABIO® SPIKY is a preparation of endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase that is authorised as a feed additive for chickens and turkeys for fattening, chickens reared for laying, turkeys reared for breeding, minor poultry species for fattening and reared for laying. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP Panel) issued two opinions on this additive. Safety aspects regarding the use of this additive in feed have been previously established. The Panel concluded that the additive is safe for the consumers and the environment and that the additive is not irritant to the skin or eyes but should be considered a potential skin sensitiser and potentially harmful if inhaled. The Panel considered that these conclusions are still valid for the current application. The current application covered the use of the additive in all poultry species at the dose of 1,100 U xylanase and 760 U glucanase per kg feed. In previous assessments, the Panel concluded that the additive is safe and efficacious under the proposed conditions of use in chickens and turkeys for fattening or raised for laying/breeding and to minor poultry species for fattening or raised for laying/breeding. In order to support the safety for laying animals, the applicant provided a tolerance trial in laying hens from which the Panel concluded that the additive is safe for laying hens at the recommended dose. The safety established in laying hens is considered to apply also to breeding hens and can be extrapolated to minor poultry species for laying. Regarding the efficacy the additive increased the metabolisable energy content of the diets in one trial and the performance of the laying hens in two trials at the recommended dose. Therefore, the FEEDAP Panel concluded that the additive has the potential to be efficacious in laying hens. This conclusion applies also to breeding hens and can be extrapolated to include all minor poultry species for laying. zootechnical additive digestibility enhancers endo‐1,4‐beta‐xylanase endo‐1,3(4)‐beta‐glucanase, poultry Nutrition. Foods and food supply Chemical technology In EFSA Journal Wiley, 2018 14(2016), 6, Seite n/a-n/a (DE-627)618834982 (DE-600)2540248-1 18314732 nnns volume:14 year:2016 number:6 pages:n/a-n/a https://doi.org/10.2903/j.efsa.2016.4510 kostenfrei https://doaj.org/article/819f7e365f474289bee7bbb172c6b943 kostenfrei https://doi.org/10.2903/j.efsa.2016.4510 kostenfrei https://doaj.org/toc/1831-4732 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_235 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2016 6 n/a-n/a
spelling	10.2903/j.efsa.2016.4510 doi (DE-627)DOAJ004312015 (DE-599)DOAJ819f7e365f474289bee7bbb172c6b943 DE-627 ger DE-627 rakwb eng TX341-641 TP1-1185 EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) verfasserin aut Safety and efficacy of ROVABIO® SPIKY (endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase) as a feed additive for all major and minor poultry species 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract ROVABIO® SPIKY is a preparation of endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase that is authorised as a feed additive for chickens and turkeys for fattening, chickens reared for laying, turkeys reared for breeding, minor poultry species for fattening and reared for laying. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP Panel) issued two opinions on this additive. Safety aspects regarding the use of this additive in feed have been previously established. The Panel concluded that the additive is safe for the consumers and the environment and that the additive is not irritant to the skin or eyes but should be considered a potential skin sensitiser and potentially harmful if inhaled. The Panel considered that these conclusions are still valid for the current application. The current application covered the use of the additive in all poultry species at the dose of 1,100 U xylanase and 760 U glucanase per kg feed. In previous assessments, the Panel concluded that the additive is safe and efficacious under the proposed conditions of use in chickens and turkeys for fattening or raised for laying/breeding and to minor poultry species for fattening or raised for laying/breeding. In order to support the safety for laying animals, the applicant provided a tolerance trial in laying hens from which the Panel concluded that the additive is safe for laying hens at the recommended dose. The safety established in laying hens is considered to apply also to breeding hens and can be extrapolated to minor poultry species for laying. Regarding the efficacy the additive increased the metabolisable energy content of the diets in one trial and the performance of the laying hens in two trials at the recommended dose. Therefore, the FEEDAP Panel concluded that the additive has the potential to be efficacious in laying hens. This conclusion applies also to breeding hens and can be extrapolated to include all minor poultry species for laying. zootechnical additive digestibility enhancers endo‐1,4‐beta‐xylanase endo‐1,3(4)‐beta‐glucanase, poultry Nutrition. Foods and food supply Chemical technology In EFSA Journal Wiley, 2018 14(2016), 6, Seite n/a-n/a (DE-627)618834982 (DE-600)2540248-1 18314732 nnns volume:14 year:2016 number:6 pages:n/a-n/a https://doi.org/10.2903/j.efsa.2016.4510 kostenfrei https://doaj.org/article/819f7e365f474289bee7bbb172c6b943 kostenfrei https://doi.org/10.2903/j.efsa.2016.4510 kostenfrei https://doaj.org/toc/1831-4732 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_235 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2016 6 n/a-n/a
allfields_unstemmed	10.2903/j.efsa.2016.4510 doi (DE-627)DOAJ004312015 (DE-599)DOAJ819f7e365f474289bee7bbb172c6b943 DE-627 ger DE-627 rakwb eng TX341-641 TP1-1185 EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) verfasserin aut Safety and efficacy of ROVABIO® SPIKY (endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase) as a feed additive for all major and minor poultry species 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract ROVABIO® SPIKY is a preparation of endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase that is authorised as a feed additive for chickens and turkeys for fattening, chickens reared for laying, turkeys reared for breeding, minor poultry species for fattening and reared for laying. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP Panel) issued two opinions on this additive. Safety aspects regarding the use of this additive in feed have been previously established. The Panel concluded that the additive is safe for the consumers and the environment and that the additive is not irritant to the skin or eyes but should be considered a potential skin sensitiser and potentially harmful if inhaled. The Panel considered that these conclusions are still valid for the current application. The current application covered the use of the additive in all poultry species at the dose of 1,100 U xylanase and 760 U glucanase per kg feed. In previous assessments, the Panel concluded that the additive is safe and efficacious under the proposed conditions of use in chickens and turkeys for fattening or raised for laying/breeding and to minor poultry species for fattening or raised for laying/breeding. In order to support the safety for laying animals, the applicant provided a tolerance trial in laying hens from which the Panel concluded that the additive is safe for laying hens at the recommended dose. The safety established in laying hens is considered to apply also to breeding hens and can be extrapolated to minor poultry species for laying. Regarding the efficacy the additive increased the metabolisable energy content of the diets in one trial and the performance of the laying hens in two trials at the recommended dose. Therefore, the FEEDAP Panel concluded that the additive has the potential to be efficacious in laying hens. This conclusion applies also to breeding hens and can be extrapolated to include all minor poultry species for laying. zootechnical additive digestibility enhancers endo‐1,4‐beta‐xylanase endo‐1,3(4)‐beta‐glucanase, poultry Nutrition. Foods and food supply Chemical technology In EFSA Journal Wiley, 2018 14(2016), 6, Seite n/a-n/a (DE-627)618834982 (DE-600)2540248-1 18314732 nnns volume:14 year:2016 number:6 pages:n/a-n/a https://doi.org/10.2903/j.efsa.2016.4510 kostenfrei https://doaj.org/article/819f7e365f474289bee7bbb172c6b943 kostenfrei https://doi.org/10.2903/j.efsa.2016.4510 kostenfrei https://doaj.org/toc/1831-4732 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_235 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2016 6 n/a-n/a
allfieldsGer	10.2903/j.efsa.2016.4510 doi (DE-627)DOAJ004312015 (DE-599)DOAJ819f7e365f474289bee7bbb172c6b943 DE-627 ger DE-627 rakwb eng TX341-641 TP1-1185 EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) verfasserin aut Safety and efficacy of ROVABIO® SPIKY (endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase) as a feed additive for all major and minor poultry species 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract ROVABIO® SPIKY is a preparation of endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase that is authorised as a feed additive for chickens and turkeys for fattening, chickens reared for laying, turkeys reared for breeding, minor poultry species for fattening and reared for laying. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP Panel) issued two opinions on this additive. Safety aspects regarding the use of this additive in feed have been previously established. The Panel concluded that the additive is safe for the consumers and the environment and that the additive is not irritant to the skin or eyes but should be considered a potential skin sensitiser and potentially harmful if inhaled. The Panel considered that these conclusions are still valid for the current application. The current application covered the use of the additive in all poultry species at the dose of 1,100 U xylanase and 760 U glucanase per kg feed. In previous assessments, the Panel concluded that the additive is safe and efficacious under the proposed conditions of use in chickens and turkeys for fattening or raised for laying/breeding and to minor poultry species for fattening or raised for laying/breeding. In order to support the safety for laying animals, the applicant provided a tolerance trial in laying hens from which the Panel concluded that the additive is safe for laying hens at the recommended dose. The safety established in laying hens is considered to apply also to breeding hens and can be extrapolated to minor poultry species for laying. Regarding the efficacy the additive increased the metabolisable energy content of the diets in one trial and the performance of the laying hens in two trials at the recommended dose. Therefore, the FEEDAP Panel concluded that the additive has the potential to be efficacious in laying hens. This conclusion applies also to breeding hens and can be extrapolated to include all minor poultry species for laying. zootechnical additive digestibility enhancers endo‐1,4‐beta‐xylanase endo‐1,3(4)‐beta‐glucanase, poultry Nutrition. Foods and food supply Chemical technology In EFSA Journal Wiley, 2018 14(2016), 6, Seite n/a-n/a (DE-627)618834982 (DE-600)2540248-1 18314732 nnns volume:14 year:2016 number:6 pages:n/a-n/a https://doi.org/10.2903/j.efsa.2016.4510 kostenfrei https://doaj.org/article/819f7e365f474289bee7bbb172c6b943 kostenfrei https://doi.org/10.2903/j.efsa.2016.4510 kostenfrei https://doaj.org/toc/1831-4732 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_235 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2016 6 n/a-n/a
allfieldsSound	10.2903/j.efsa.2016.4510 doi (DE-627)DOAJ004312015 (DE-599)DOAJ819f7e365f474289bee7bbb172c6b943 DE-627 ger DE-627 rakwb eng TX341-641 TP1-1185 EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) verfasserin aut Safety and efficacy of ROVABIO® SPIKY (endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase) as a feed additive for all major and minor poultry species 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract ROVABIO® SPIKY is a preparation of endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase that is authorised as a feed additive for chickens and turkeys for fattening, chickens reared for laying, turkeys reared for breeding, minor poultry species for fattening and reared for laying. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP Panel) issued two opinions on this additive. Safety aspects regarding the use of this additive in feed have been previously established. The Panel concluded that the additive is safe for the consumers and the environment and that the additive is not irritant to the skin or eyes but should be considered a potential skin sensitiser and potentially harmful if inhaled. The Panel considered that these conclusions are still valid for the current application. The current application covered the use of the additive in all poultry species at the dose of 1,100 U xylanase and 760 U glucanase per kg feed. In previous assessments, the Panel concluded that the additive is safe and efficacious under the proposed conditions of use in chickens and turkeys for fattening or raised for laying/breeding and to minor poultry species for fattening or raised for laying/breeding. In order to support the safety for laying animals, the applicant provided a tolerance trial in laying hens from which the Panel concluded that the additive is safe for laying hens at the recommended dose. The safety established in laying hens is considered to apply also to breeding hens and can be extrapolated to minor poultry species for laying. Regarding the efficacy the additive increased the metabolisable energy content of the diets in one trial and the performance of the laying hens in two trials at the recommended dose. Therefore, the FEEDAP Panel concluded that the additive has the potential to be efficacious in laying hens. This conclusion applies also to breeding hens and can be extrapolated to include all minor poultry species for laying. zootechnical additive digestibility enhancers endo‐1,4‐beta‐xylanase endo‐1,3(4)‐beta‐glucanase, poultry Nutrition. Foods and food supply Chemical technology In EFSA Journal Wiley, 2018 14(2016), 6, Seite n/a-n/a (DE-627)618834982 (DE-600)2540248-1 18314732 nnns volume:14 year:2016 number:6 pages:n/a-n/a https://doi.org/10.2903/j.efsa.2016.4510 kostenfrei https://doaj.org/article/819f7e365f474289bee7bbb172c6b943 kostenfrei https://doi.org/10.2903/j.efsa.2016.4510 kostenfrei https://doaj.org/toc/1831-4732 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_235 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2016 6 n/a-n/a
language	English
source	In EFSA Journal 14(2016), 6, Seite n/a-n/a volume:14 year:2016 number:6 pages:n/a-n/a
sourceStr	In EFSA Journal 14(2016), 6, Seite n/a-n/a volume:14 year:2016 number:6 pages:n/a-n/a
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	zootechnical additive digestibility enhancers endo‐1,4‐beta‐xylanase endo‐1,3(4)‐beta‐glucanase, poultry Nutrition. Foods and food supply Chemical technology
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container_title	EFSA Journal
authorswithroles_txt_mv	EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) @@aut@@
publishDateDaySort_date	2016-01-01T00:00:00Z
hierarchy_top_id	618834982
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language_de	englisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ004312015</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230309183337.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230225s2016 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.2903/j.efsa.2016.4510</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ004312015</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ819f7e365f474289bee7bbb172c6b943</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">TX341-641</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">TP1-1185</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Safety and efficacy of ROVABIO® SPIKY (endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase) as a feed additive for all major and minor poultry species</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2016</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract ROVABIO® SPIKY is a preparation of endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase that is authorised as a feed additive for chickens and turkeys for fattening, chickens reared for laying, turkeys reared for breeding, minor poultry species for fattening and reared for laying. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP Panel) issued two opinions on this additive. Safety aspects regarding the use of this additive in feed have been previously established. The Panel concluded that the additive is safe for the consumers and the environment and that the additive is not irritant to the skin or eyes but should be considered a potential skin sensitiser and potentially harmful if inhaled. The Panel considered that these conclusions are still valid for the current application. The current application covered the use of the additive in all poultry species at the dose of 1,100 U xylanase and 760 U glucanase per kg feed. In previous assessments, the Panel concluded that the additive is safe and efficacious under the proposed conditions of use in chickens and turkeys for fattening or raised for laying/breeding and to minor poultry species for fattening or raised for laying/breeding. In order to support the safety for laying animals, the applicant provided a tolerance trial in laying hens from which the Panel concluded that the additive is safe for laying hens at the recommended dose. The safety established in laying hens is considered to apply also to breeding hens and can be extrapolated to minor poultry species for laying. Regarding the efficacy the additive increased the metabolisable energy content of the diets in one trial and the performance of the laying hens in two trials at the recommended dose. Therefore, the FEEDAP Panel concluded that the additive has the potential to be efficacious in laying hens. 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callnumber-first	T - Technology
author	EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
spellingShingle	EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) misc TX341-641 misc TP1-1185 misc zootechnical additive misc digestibility enhancers misc endo‐1,4‐beta‐xylanase misc endo‐1,3(4)‐beta‐glucanase, poultry misc Nutrition. Foods and food supply misc Chemical technology Safety and efficacy of ROVABIO® SPIKY (endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase) as a feed additive for all major and minor poultry species
authorStr	EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
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topic_title	TX341-641 TP1-1185 Safety and efficacy of ROVABIO® SPIKY (endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase) as a feed additive for all major and minor poultry species zootechnical additive digestibility enhancers endo‐1,4‐beta‐xylanase endo‐1,3(4)‐beta‐glucanase, poultry
topic	misc TX341-641 misc TP1-1185 misc zootechnical additive misc digestibility enhancers misc endo‐1,4‐beta‐xylanase misc endo‐1,3(4)‐beta‐glucanase, poultry misc Nutrition. Foods and food supply misc Chemical technology
topic_unstemmed	misc TX341-641 misc TP1-1185 misc zootechnical additive misc digestibility enhancers misc endo‐1,4‐beta‐xylanase misc endo‐1,3(4)‐beta‐glucanase, poultry misc Nutrition. Foods and food supply misc Chemical technology
topic_browse	misc TX341-641 misc TP1-1185 misc zootechnical additive misc digestibility enhancers misc endo‐1,4‐beta‐xylanase misc endo‐1,3(4)‐beta‐glucanase, poultry misc Nutrition. Foods and food supply misc Chemical technology
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title	Safety and efficacy of ROVABIO® SPIKY (endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase) as a feed additive for all major and minor poultry species
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title_full	Safety and efficacy of ROVABIO® SPIKY (endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase) as a feed additive for all major and minor poultry species
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doi_str_mv	10.2903/j.efsa.2016.4510
title_sort	safety and efficacy of rovabio® spiky (endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase) as a feed additive for all major and minor poultry species
callnumber	TX341-641
title_auth	Safety and efficacy of ROVABIO® SPIKY (endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase) as a feed additive for all major and minor poultry species
abstract	Abstract ROVABIO® SPIKY is a preparation of endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase that is authorised as a feed additive for chickens and turkeys for fattening, chickens reared for laying, turkeys reared for breeding, minor poultry species for fattening and reared for laying. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP Panel) issued two opinions on this additive. Safety aspects regarding the use of this additive in feed have been previously established. The Panel concluded that the additive is safe for the consumers and the environment and that the additive is not irritant to the skin or eyes but should be considered a potential skin sensitiser and potentially harmful if inhaled. The Panel considered that these conclusions are still valid for the current application. The current application covered the use of the additive in all poultry species at the dose of 1,100 U xylanase and 760 U glucanase per kg feed. In previous assessments, the Panel concluded that the additive is safe and efficacious under the proposed conditions of use in chickens and turkeys for fattening or raised for laying/breeding and to minor poultry species for fattening or raised for laying/breeding. In order to support the safety for laying animals, the applicant provided a tolerance trial in laying hens from which the Panel concluded that the additive is safe for laying hens at the recommended dose. The safety established in laying hens is considered to apply also to breeding hens and can be extrapolated to minor poultry species for laying. Regarding the efficacy the additive increased the metabolisable energy content of the diets in one trial and the performance of the laying hens in two trials at the recommended dose. Therefore, the FEEDAP Panel concluded that the additive has the potential to be efficacious in laying hens. This conclusion applies also to breeding hens and can be extrapolated to include all minor poultry species for laying.
abstractGer	Abstract ROVABIO® SPIKY is a preparation of endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase that is authorised as a feed additive for chickens and turkeys for fattening, chickens reared for laying, turkeys reared for breeding, minor poultry species for fattening and reared for laying. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP Panel) issued two opinions on this additive. Safety aspects regarding the use of this additive in feed have been previously established. The Panel concluded that the additive is safe for the consumers and the environment and that the additive is not irritant to the skin or eyes but should be considered a potential skin sensitiser and potentially harmful if inhaled. The Panel considered that these conclusions are still valid for the current application. The current application covered the use of the additive in all poultry species at the dose of 1,100 U xylanase and 760 U glucanase per kg feed. In previous assessments, the Panel concluded that the additive is safe and efficacious under the proposed conditions of use in chickens and turkeys for fattening or raised for laying/breeding and to minor poultry species for fattening or raised for laying/breeding. In order to support the safety for laying animals, the applicant provided a tolerance trial in laying hens from which the Panel concluded that the additive is safe for laying hens at the recommended dose. The safety established in laying hens is considered to apply also to breeding hens and can be extrapolated to minor poultry species for laying. Regarding the efficacy the additive increased the metabolisable energy content of the diets in one trial and the performance of the laying hens in two trials at the recommended dose. Therefore, the FEEDAP Panel concluded that the additive has the potential to be efficacious in laying hens. This conclusion applies also to breeding hens and can be extrapolated to include all minor poultry species for laying.
abstract_unstemmed	Abstract ROVABIO® SPIKY is a preparation of endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase that is authorised as a feed additive for chickens and turkeys for fattening, chickens reared for laying, turkeys reared for breeding, minor poultry species for fattening and reared for laying. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP Panel) issued two opinions on this additive. Safety aspects regarding the use of this additive in feed have been previously established. The Panel concluded that the additive is safe for the consumers and the environment and that the additive is not irritant to the skin or eyes but should be considered a potential skin sensitiser and potentially harmful if inhaled. The Panel considered that these conclusions are still valid for the current application. The current application covered the use of the additive in all poultry species at the dose of 1,100 U xylanase and 760 U glucanase per kg feed. In previous assessments, the Panel concluded that the additive is safe and efficacious under the proposed conditions of use in chickens and turkeys for fattening or raised for laying/breeding and to minor poultry species for fattening or raised for laying/breeding. In order to support the safety for laying animals, the applicant provided a tolerance trial in laying hens from which the Panel concluded that the additive is safe for laying hens at the recommended dose. The safety established in laying hens is considered to apply also to breeding hens and can be extrapolated to minor poultry species for laying. Regarding the efficacy the additive increased the metabolisable energy content of the diets in one trial and the performance of the laying hens in two trials at the recommended dose. Therefore, the FEEDAP Panel concluded that the additive has the potential to be efficacious in laying hens. This conclusion applies also to breeding hens and can be extrapolated to include all minor poultry species for laying.
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title_short	Safety and efficacy of ROVABIO® SPIKY (endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase) as a feed additive for all major and minor poultry species
url	https://doi.org/10.2903/j.efsa.2016.4510 https://doaj.org/article/819f7e365f474289bee7bbb172c6b943 https://doaj.org/toc/1831-4732
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up_date	2024-07-03T23:07:12.828Z
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fullrecord_marcxml	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ004312015</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230309183337.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230225s2016 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.2903/j.efsa.2016.4510</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ004312015</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ819f7e365f474289bee7bbb172c6b943</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">TX341-641</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">TP1-1185</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Safety and efficacy of ROVABIO® SPIKY (endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase) as a feed additive for all major and minor poultry species</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2016</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract ROVABIO® SPIKY is a preparation of endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase that is authorised as a feed additive for chickens and turkeys for fattening, chickens reared for laying, turkeys reared for breeding, minor poultry species for fattening and reared for laying. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP Panel) issued two opinions on this additive. Safety aspects regarding the use of this additive in feed have been previously established. The Panel concluded that the additive is safe for the consumers and the environment and that the additive is not irritant to the skin or eyes but should be considered a potential skin sensitiser and potentially harmful if inhaled. The Panel considered that these conclusions are still valid for the current application. The current application covered the use of the additive in all poultry species at the dose of 1,100 U xylanase and 760 U glucanase per kg feed. In previous assessments, the Panel concluded that the additive is safe and efficacious under the proposed conditions of use in chickens and turkeys for fattening or raised for laying/breeding and to minor poultry species for fattening or raised for laying/breeding. In order to support the safety for laying animals, the applicant provided a tolerance trial in laying hens from which the Panel concluded that the additive is safe for laying hens at the recommended dose. The safety established in laying hens is considered to apply also to breeding hens and can be extrapolated to minor poultry species for laying. Regarding the efficacy the additive increased the metabolisable energy content of the diets in one trial and the performance of the laying hens in two trials at the recommended dose. Therefore, the FEEDAP Panel concluded that the additive has the potential to be efficacious in laying hens. 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Safety and efficacy of ROVABIO® SPIKY (endo‐1,4‐beta‐xylanase and endo‐1,3(4)‐beta‐glucanase) as a feed additive for all major and minor poultry species

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