A Patient with Giant Rippled-Pattern Sebaceoma in the Occipital Region

A 72-year-old male visited a nearby hospital with a large tumor in his occipital region, which had existed since 20 years. Since malignant tumor was suspected, he was referred to our department. At the initial consultation, an elastic-hard, yellow-brown, sessile tumor, measuring 8 × 7 × 5 cm and wit...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Masayuki Takahashi [verfasserIn] Masaru Arima [verfasserIn] Yohei Iwata [verfasserIn] Kayoko Suzuki [verfasserIn] Yoshikazu Mizoguchi [verfasserIn] Makoto Kuroda [verfasserIn] Kayoko Matsunaga [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2016

Schlagwörter:	Giant sebaceoma Occipital region Rippled pattern

Übergeordnetes Werk:	In: Case Reports in Dermatology - Karger Publishers, 2009, 8(2016), 2, Seite 107-111
Übergeordnetes Werk:	volume:8 ; year:2016 ; number:2 ; pages:107-111

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1159/000445935

Katalog-ID:	DOAJ00510985X

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520			\|a A 72-year-old male visited a nearby hospital with a large tumor in his occipital region, which had existed since 20 years. Since malignant tumor was suspected, he was referred to our department. At the initial consultation, an elastic-hard, yellow-brown, sessile tumor, measuring 8 × 7 × 5 cm and with a flat surface, was observed in the occipital region. The tumor was resected and covered with artificial dermis. Histopathologically, the lesion was composed of basal-cell-like cells with nest formation in the dermis. A rippled pattern, or the single-line arrangement of tumor cells involving the stroma, was present. In addition, some tumor clusters revealed the differentiation to sebaceous glands, and these cells were positive for cytokeratin (AE1/AE3) and epithelial membrane antigen, which is consistent with the staining of sebaceous glands. On the contrary, tumor cells were negative for epithelial antigen (Ber-EP4), and Ki67 (MIB1) index was 5% or lower. Therefore, we diagnosed the tumor as rippled-pattern sebaceoma and not as basal cell carcinoma. Although this case was quite unique in its large size, immunostaining was useful for the definite diagnosis.
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allfieldsSound	10.1159/000445935 doi (DE-627)DOAJ00510985X (DE-599)DOAJfc910b7eb82d4e6288e82aeffded35b6 DE-627 ger DE-627 rakwb eng RL1-803 Masayuki Takahashi verfasserin aut A Patient with Giant Rippled-Pattern Sebaceoma in the Occipital Region 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A 72-year-old male visited a nearby hospital with a large tumor in his occipital region, which had existed since 20 years. Since malignant tumor was suspected, he was referred to our department. At the initial consultation, an elastic-hard, yellow-brown, sessile tumor, measuring 8 × 7 × 5 cm and with a flat surface, was observed in the occipital region. The tumor was resected and covered with artificial dermis. Histopathologically, the lesion was composed of basal-cell-like cells with nest formation in the dermis. A rippled pattern, or the single-line arrangement of tumor cells involving the stroma, was present. In addition, some tumor clusters revealed the differentiation to sebaceous glands, and these cells were positive for cytokeratin (AE1/AE3) and epithelial membrane antigen, which is consistent with the staining of sebaceous glands. On the contrary, tumor cells were negative for epithelial antigen (Ber-EP4), and Ki67 (MIB1) index was 5% or lower. Therefore, we diagnosed the tumor as rippled-pattern sebaceoma and not as basal cell carcinoma. Although this case was quite unique in its large size, immunostaining was useful for the definite diagnosis. Giant sebaceoma Occipital region Rippled pattern Dermatology Masaru Arima verfasserin aut Yohei Iwata verfasserin aut Kayoko Suzuki verfasserin aut Yoshikazu Mizoguchi verfasserin aut Makoto Kuroda verfasserin aut Kayoko Matsunaga verfasserin aut In Case Reports in Dermatology Karger Publishers, 2009 8(2016), 2, Seite 107-111 (DE-627)60521266X (DE-600)2505300-0 16626567 nnns volume:8 year:2016 number:2 pages:107-111 https://doi.org/10.1159/000445935 kostenfrei https://doaj.org/article/fc910b7eb82d4e6288e82aeffded35b6 kostenfrei http://www.karger.com/Article/FullText/445935 kostenfrei https://doaj.org/toc/1662-6567 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2018 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2016 2 107-111
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authorswithroles_txt_mv	Masayuki Takahashi @@aut@@ Masaru Arima @@aut@@ Yohei Iwata @@aut@@ Kayoko Suzuki @@aut@@ Yoshikazu Mizoguchi @@aut@@ Makoto Kuroda @@aut@@ Kayoko Matsunaga @@aut@@
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callnumber-first	R - Medicine
author	Masayuki Takahashi
spellingShingle	Masayuki Takahashi misc RL1-803 misc Giant sebaceoma misc Occipital region misc Rippled pattern misc Dermatology A Patient with Giant Rippled-Pattern Sebaceoma in the Occipital Region
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topic_title	RL1-803 A Patient with Giant Rippled-Pattern Sebaceoma in the Occipital Region Giant sebaceoma Occipital region Rippled pattern
topic	misc RL1-803 misc Giant sebaceoma misc Occipital region misc Rippled pattern misc Dermatology
topic_unstemmed	misc RL1-803 misc Giant sebaceoma misc Occipital region misc Rippled pattern misc Dermatology
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title	A Patient with Giant Rippled-Pattern Sebaceoma in the Occipital Region
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title_full	A Patient with Giant Rippled-Pattern Sebaceoma in the Occipital Region
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author_browse	Masayuki Takahashi Masaru Arima Yohei Iwata Kayoko Suzuki Yoshikazu Mizoguchi Makoto Kuroda Kayoko Matsunaga
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title_sort	patient with giant rippled-pattern sebaceoma in the occipital region
callnumber	RL1-803
title_auth	A Patient with Giant Rippled-Pattern Sebaceoma in the Occipital Region
abstract	A 72-year-old male visited a nearby hospital with a large tumor in his occipital region, which had existed since 20 years. Since malignant tumor was suspected, he was referred to our department. At the initial consultation, an elastic-hard, yellow-brown, sessile tumor, measuring 8 × 7 × 5 cm and with a flat surface, was observed in the occipital region. The tumor was resected and covered with artificial dermis. Histopathologically, the lesion was composed of basal-cell-like cells with nest formation in the dermis. A rippled pattern, or the single-line arrangement of tumor cells involving the stroma, was present. In addition, some tumor clusters revealed the differentiation to sebaceous glands, and these cells were positive for cytokeratin (AE1/AE3) and epithelial membrane antigen, which is consistent with the staining of sebaceous glands. On the contrary, tumor cells were negative for epithelial antigen (Ber-EP4), and Ki67 (MIB1) index was 5% or lower. Therefore, we diagnosed the tumor as rippled-pattern sebaceoma and not as basal cell carcinoma. Although this case was quite unique in its large size, immunostaining was useful for the definite diagnosis.
abstractGer	A 72-year-old male visited a nearby hospital with a large tumor in his occipital region, which had existed since 20 years. Since malignant tumor was suspected, he was referred to our department. At the initial consultation, an elastic-hard, yellow-brown, sessile tumor, measuring 8 × 7 × 5 cm and with a flat surface, was observed in the occipital region. The tumor was resected and covered with artificial dermis. Histopathologically, the lesion was composed of basal-cell-like cells with nest formation in the dermis. A rippled pattern, or the single-line arrangement of tumor cells involving the stroma, was present. In addition, some tumor clusters revealed the differentiation to sebaceous glands, and these cells were positive for cytokeratin (AE1/AE3) and epithelial membrane antigen, which is consistent with the staining of sebaceous glands. On the contrary, tumor cells were negative for epithelial antigen (Ber-EP4), and Ki67 (MIB1) index was 5% or lower. Therefore, we diagnosed the tumor as rippled-pattern sebaceoma and not as basal cell carcinoma. Although this case was quite unique in its large size, immunostaining was useful for the definite diagnosis.
abstract_unstemmed	A 72-year-old male visited a nearby hospital with a large tumor in his occipital region, which had existed since 20 years. Since malignant tumor was suspected, he was referred to our department. At the initial consultation, an elastic-hard, yellow-brown, sessile tumor, measuring 8 × 7 × 5 cm and with a flat surface, was observed in the occipital region. The tumor was resected and covered with artificial dermis. Histopathologically, the lesion was composed of basal-cell-like cells with nest formation in the dermis. A rippled pattern, or the single-line arrangement of tumor cells involving the stroma, was present. In addition, some tumor clusters revealed the differentiation to sebaceous glands, and these cells were positive for cytokeratin (AE1/AE3) and epithelial membrane antigen, which is consistent with the staining of sebaceous glands. On the contrary, tumor cells were negative for epithelial antigen (Ber-EP4), and Ki67 (MIB1) index was 5% or lower. Therefore, we diagnosed the tumor as rippled-pattern sebaceoma and not as basal cell carcinoma. Although this case was quite unique in its large size, immunostaining was useful for the definite diagnosis.
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title_short	A Patient with Giant Rippled-Pattern Sebaceoma in the Occipital Region
url	https://doi.org/10.1159/000445935 https://doaj.org/article/fc910b7eb82d4e6288e82aeffded35b6 http://www.karger.com/Article/FullText/445935 https://doaj.org/toc/1662-6567
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author2	Masaru Arima Yohei Iwata Kayoko Suzuki Yoshikazu Mizoguchi Makoto Kuroda Kayoko Matsunaga
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up_date	2024-07-04T02:20:54.519Z
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A Patient with Giant Rippled-Pattern Sebaceoma in the Occipital Region

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