Enhancement of signal-to-noise ratio for fluorescence endoscope image based on fast digital lock-in algorithm

In this paper, the signal-to-noise ratios (SNR) of two image channels were enhanced with the fast digital lock-in algorithm. In order to simultaneously improve the quality of white and fluorescence images obtained by fluorescence endoscope, and improve the SNR to achieve a better image processing ef...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Huiquan Wang [verfasserIn] Meng Hu [verfasserIn] Fang Xia [verfasserIn] Meng Guo [verfasserIn] Shengzhao Zhang [verfasserIn] Zhe Zhao [verfasserIn] Guang Han [verfasserIn] Jinhai Wang [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	fluorescence endoscope tumour fast digital lock-in algorithm image snr

Übergeordnetes Werk:	In: Royal Society Open Science - The Royal Society, 2015, 8(2021), 3
Übergeordnetes Werk:	volume:8 ; year:2021 ; number:3

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1098/rsos.200779

Katalog-ID:	DOAJ005495385

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allfields	10.1098/rsos.200779 doi (DE-627)DOAJ005495385 (DE-599)DOAJec5a75c1ae7340bcb479f4bdc58c533b DE-627 ger DE-627 rakwb eng Huiquan Wang verfasserin aut Enhancement of signal-to-noise ratio for fluorescence endoscope image based on fast digital lock-in algorithm 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier In this paper, the signal-to-noise ratios (SNR) of two image channels were enhanced with the fast digital lock-in algorithm. In order to simultaneously improve the quality of white and fluorescence images obtained by fluorescence endoscope, and improve the SNR to achieve a better image processing effect, two sources of white light and near-infrared light of a fluorescence endoscope were modulated, then the acquired images were demodulated into white and fluorescence images. A fluorescent endoscope experimental platform was setup to acquire endoscopic images of a target dyed by indocyanine green. The experimental results showed that the SNR of white and fluorescent images without the lock-in algorithm were 36.56 dB and 33.47 dB, respectively. However, with the lock-in algorithm, the SNR of white and fluorescent images were 39.54 dB and 35.70 dB, respectively. The SNR of white and fluorescent images was increased by 8.2% and 6.7%, respectively, by appling the digital lock-in algorithm. Therefore, this novel fluorescence endoscope based on the fast digital lock-in algorithm can rapidly and simultaneously obtain two-channel images of white light and fluorescence, effectively enhance the SNR of white and fluorescent images, and improve the imaging quality. fluorescence endoscope tumour fast digital lock-in algorithm image snr Science Q Meng Hu verfasserin aut Fang Xia verfasserin aut Meng Guo verfasserin aut Shengzhao Zhang verfasserin aut Zhe Zhao verfasserin aut Guang Han verfasserin aut Jinhai Wang verfasserin aut In Royal Society Open Science The Royal Society, 2015 8(2021), 3 (DE-627)798561173 (DE-600)2787755-3 20545703 nnns volume:8 year:2021 number:3 https://doi.org/10.1098/rsos.200779 kostenfrei https://doaj.org/article/ec5a75c1ae7340bcb479f4bdc58c533b kostenfrei https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.200779 kostenfrei https://doaj.org/toc/2054-5703 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2005 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2021 3
spelling	10.1098/rsos.200779 doi (DE-627)DOAJ005495385 (DE-599)DOAJec5a75c1ae7340bcb479f4bdc58c533b DE-627 ger DE-627 rakwb eng Huiquan Wang verfasserin aut Enhancement of signal-to-noise ratio for fluorescence endoscope image based on fast digital lock-in algorithm 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier In this paper, the signal-to-noise ratios (SNR) of two image channels were enhanced with the fast digital lock-in algorithm. In order to simultaneously improve the quality of white and fluorescence images obtained by fluorescence endoscope, and improve the SNR to achieve a better image processing effect, two sources of white light and near-infrared light of a fluorescence endoscope were modulated, then the acquired images were demodulated into white and fluorescence images. A fluorescent endoscope experimental platform was setup to acquire endoscopic images of a target dyed by indocyanine green. The experimental results showed that the SNR of white and fluorescent images without the lock-in algorithm were 36.56 dB and 33.47 dB, respectively. However, with the lock-in algorithm, the SNR of white and fluorescent images were 39.54 dB and 35.70 dB, respectively. The SNR of white and fluorescent images was increased by 8.2% and 6.7%, respectively, by appling the digital lock-in algorithm. Therefore, this novel fluorescence endoscope based on the fast digital lock-in algorithm can rapidly and simultaneously obtain two-channel images of white light and fluorescence, effectively enhance the SNR of white and fluorescent images, and improve the imaging quality. fluorescence endoscope tumour fast digital lock-in algorithm image snr Science Q Meng Hu verfasserin aut Fang Xia verfasserin aut Meng Guo verfasserin aut Shengzhao Zhang verfasserin aut Zhe Zhao verfasserin aut Guang Han verfasserin aut Jinhai Wang verfasserin aut In Royal Society Open Science The Royal Society, 2015 8(2021), 3 (DE-627)798561173 (DE-600)2787755-3 20545703 nnns volume:8 year:2021 number:3 https://doi.org/10.1098/rsos.200779 kostenfrei https://doaj.org/article/ec5a75c1ae7340bcb479f4bdc58c533b kostenfrei https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.200779 kostenfrei https://doaj.org/toc/2054-5703 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2005 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2021 3
allfields_unstemmed	10.1098/rsos.200779 doi (DE-627)DOAJ005495385 (DE-599)DOAJec5a75c1ae7340bcb479f4bdc58c533b DE-627 ger DE-627 rakwb eng Huiquan Wang verfasserin aut Enhancement of signal-to-noise ratio for fluorescence endoscope image based on fast digital lock-in algorithm 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier In this paper, the signal-to-noise ratios (SNR) of two image channels were enhanced with the fast digital lock-in algorithm. In order to simultaneously improve the quality of white and fluorescence images obtained by fluorescence endoscope, and improve the SNR to achieve a better image processing effect, two sources of white light and near-infrared light of a fluorescence endoscope were modulated, then the acquired images were demodulated into white and fluorescence images. A fluorescent endoscope experimental platform was setup to acquire endoscopic images of a target dyed by indocyanine green. The experimental results showed that the SNR of white and fluorescent images without the lock-in algorithm were 36.56 dB and 33.47 dB, respectively. However, with the lock-in algorithm, the SNR of white and fluorescent images were 39.54 dB and 35.70 dB, respectively. The SNR of white and fluorescent images was increased by 8.2% and 6.7%, respectively, by appling the digital lock-in algorithm. Therefore, this novel fluorescence endoscope based on the fast digital lock-in algorithm can rapidly and simultaneously obtain two-channel images of white light and fluorescence, effectively enhance the SNR of white and fluorescent images, and improve the imaging quality. fluorescence endoscope tumour fast digital lock-in algorithm image snr Science Q Meng Hu verfasserin aut Fang Xia verfasserin aut Meng Guo verfasserin aut Shengzhao Zhang verfasserin aut Zhe Zhao verfasserin aut Guang Han verfasserin aut Jinhai Wang verfasserin aut In Royal Society Open Science The Royal Society, 2015 8(2021), 3 (DE-627)798561173 (DE-600)2787755-3 20545703 nnns volume:8 year:2021 number:3 https://doi.org/10.1098/rsos.200779 kostenfrei https://doaj.org/article/ec5a75c1ae7340bcb479f4bdc58c533b kostenfrei https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.200779 kostenfrei https://doaj.org/toc/2054-5703 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2005 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2021 3
allfieldsGer	10.1098/rsos.200779 doi (DE-627)DOAJ005495385 (DE-599)DOAJec5a75c1ae7340bcb479f4bdc58c533b DE-627 ger DE-627 rakwb eng Huiquan Wang verfasserin aut Enhancement of signal-to-noise ratio for fluorescence endoscope image based on fast digital lock-in algorithm 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier In this paper, the signal-to-noise ratios (SNR) of two image channels were enhanced with the fast digital lock-in algorithm. In order to simultaneously improve the quality of white and fluorescence images obtained by fluorescence endoscope, and improve the SNR to achieve a better image processing effect, two sources of white light and near-infrared light of a fluorescence endoscope were modulated, then the acquired images were demodulated into white and fluorescence images. A fluorescent endoscope experimental platform was setup to acquire endoscopic images of a target dyed by indocyanine green. The experimental results showed that the SNR of white and fluorescent images without the lock-in algorithm were 36.56 dB and 33.47 dB, respectively. However, with the lock-in algorithm, the SNR of white and fluorescent images were 39.54 dB and 35.70 dB, respectively. The SNR of white and fluorescent images was increased by 8.2% and 6.7%, respectively, by appling the digital lock-in algorithm. Therefore, this novel fluorescence endoscope based on the fast digital lock-in algorithm can rapidly and simultaneously obtain two-channel images of white light and fluorescence, effectively enhance the SNR of white and fluorescent images, and improve the imaging quality. fluorescence endoscope tumour fast digital lock-in algorithm image snr Science Q Meng Hu verfasserin aut Fang Xia verfasserin aut Meng Guo verfasserin aut Shengzhao Zhang verfasserin aut Zhe Zhao verfasserin aut Guang Han verfasserin aut Jinhai Wang verfasserin aut In Royal Society Open Science The Royal Society, 2015 8(2021), 3 (DE-627)798561173 (DE-600)2787755-3 20545703 nnns volume:8 year:2021 number:3 https://doi.org/10.1098/rsos.200779 kostenfrei https://doaj.org/article/ec5a75c1ae7340bcb479f4bdc58c533b kostenfrei https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.200779 kostenfrei https://doaj.org/toc/2054-5703 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2005 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2021 3
allfieldsSound	10.1098/rsos.200779 doi (DE-627)DOAJ005495385 (DE-599)DOAJec5a75c1ae7340bcb479f4bdc58c533b DE-627 ger DE-627 rakwb eng Huiquan Wang verfasserin aut Enhancement of signal-to-noise ratio for fluorescence endoscope image based on fast digital lock-in algorithm 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier In this paper, the signal-to-noise ratios (SNR) of two image channels were enhanced with the fast digital lock-in algorithm. In order to simultaneously improve the quality of white and fluorescence images obtained by fluorescence endoscope, and improve the SNR to achieve a better image processing effect, two sources of white light and near-infrared light of a fluorescence endoscope were modulated, then the acquired images were demodulated into white and fluorescence images. A fluorescent endoscope experimental platform was setup to acquire endoscopic images of a target dyed by indocyanine green. The experimental results showed that the SNR of white and fluorescent images without the lock-in algorithm were 36.56 dB and 33.47 dB, respectively. However, with the lock-in algorithm, the SNR of white and fluorescent images were 39.54 dB and 35.70 dB, respectively. The SNR of white and fluorescent images was increased by 8.2% and 6.7%, respectively, by appling the digital lock-in algorithm. Therefore, this novel fluorescence endoscope based on the fast digital lock-in algorithm can rapidly and simultaneously obtain two-channel images of white light and fluorescence, effectively enhance the SNR of white and fluorescent images, and improve the imaging quality. fluorescence endoscope tumour fast digital lock-in algorithm image snr Science Q Meng Hu verfasserin aut Fang Xia verfasserin aut Meng Guo verfasserin aut Shengzhao Zhang verfasserin aut Zhe Zhao verfasserin aut Guang Han verfasserin aut Jinhai Wang verfasserin aut In Royal Society Open Science The Royal Society, 2015 8(2021), 3 (DE-627)798561173 (DE-600)2787755-3 20545703 nnns volume:8 year:2021 number:3 https://doi.org/10.1098/rsos.200779 kostenfrei https://doaj.org/article/ec5a75c1ae7340bcb479f4bdc58c533b kostenfrei https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.200779 kostenfrei https://doaj.org/toc/2054-5703 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2005 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2021 3
language	English
source	In Royal Society Open Science 8(2021), 3 volume:8 year:2021 number:3
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institution	findex.gbv.de
topic_facet	fluorescence endoscope tumour fast digital lock-in algorithm image snr Science Q
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container_title	Royal Society Open Science
authorswithroles_txt_mv	Huiquan Wang @@aut@@ Meng Hu @@aut@@ Fang Xia @@aut@@ Meng Guo @@aut@@ Shengzhao Zhang @@aut@@ Zhe Zhao @@aut@@ Guang Han @@aut@@ Jinhai Wang @@aut@@
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author	Huiquan Wang
spellingShingle	Huiquan Wang misc fluorescence endoscope misc tumour misc fast digital lock-in algorithm misc image snr misc Science misc Q Enhancement of signal-to-noise ratio for fluorescence endoscope image based on fast digital lock-in algorithm
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topic_title	Enhancement of signal-to-noise ratio for fluorescence endoscope image based on fast digital lock-in algorithm fluorescence endoscope tumour fast digital lock-in algorithm image snr
topic	misc fluorescence endoscope misc tumour misc fast digital lock-in algorithm misc image snr misc Science misc Q
topic_unstemmed	misc fluorescence endoscope misc tumour misc fast digital lock-in algorithm misc image snr misc Science misc Q
topic_browse	misc fluorescence endoscope misc tumour misc fast digital lock-in algorithm misc image snr misc Science misc Q
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title	Enhancement of signal-to-noise ratio for fluorescence endoscope image based on fast digital lock-in algorithm
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title_full	Enhancement of signal-to-noise ratio for fluorescence endoscope image based on fast digital lock-in algorithm
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author_browse	Huiquan Wang Meng Hu Fang Xia Meng Guo Shengzhao Zhang Zhe Zhao Guang Han Jinhai Wang
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title_sort	enhancement of signal-to-noise ratio for fluorescence endoscope image based on fast digital lock-in algorithm
title_auth	Enhancement of signal-to-noise ratio for fluorescence endoscope image based on fast digital lock-in algorithm
abstract	In this paper, the signal-to-noise ratios (SNR) of two image channels were enhanced with the fast digital lock-in algorithm. In order to simultaneously improve the quality of white and fluorescence images obtained by fluorescence endoscope, and improve the SNR to achieve a better image processing effect, two sources of white light and near-infrared light of a fluorescence endoscope were modulated, then the acquired images were demodulated into white and fluorescence images. A fluorescent endoscope experimental platform was setup to acquire endoscopic images of a target dyed by indocyanine green. The experimental results showed that the SNR of white and fluorescent images without the lock-in algorithm were 36.56 dB and 33.47 dB, respectively. However, with the lock-in algorithm, the SNR of white and fluorescent images were 39.54 dB and 35.70 dB, respectively. The SNR of white and fluorescent images was increased by 8.2% and 6.7%, respectively, by appling the digital lock-in algorithm. Therefore, this novel fluorescence endoscope based on the fast digital lock-in algorithm can rapidly and simultaneously obtain two-channel images of white light and fluorescence, effectively enhance the SNR of white and fluorescent images, and improve the imaging quality.
abstractGer	In this paper, the signal-to-noise ratios (SNR) of two image channels were enhanced with the fast digital lock-in algorithm. In order to simultaneously improve the quality of white and fluorescence images obtained by fluorescence endoscope, and improve the SNR to achieve a better image processing effect, two sources of white light and near-infrared light of a fluorescence endoscope were modulated, then the acquired images were demodulated into white and fluorescence images. A fluorescent endoscope experimental platform was setup to acquire endoscopic images of a target dyed by indocyanine green. The experimental results showed that the SNR of white and fluorescent images without the lock-in algorithm were 36.56 dB and 33.47 dB, respectively. However, with the lock-in algorithm, the SNR of white and fluorescent images were 39.54 dB and 35.70 dB, respectively. The SNR of white and fluorescent images was increased by 8.2% and 6.7%, respectively, by appling the digital lock-in algorithm. Therefore, this novel fluorescence endoscope based on the fast digital lock-in algorithm can rapidly and simultaneously obtain two-channel images of white light and fluorescence, effectively enhance the SNR of white and fluorescent images, and improve the imaging quality.
abstract_unstemmed	In this paper, the signal-to-noise ratios (SNR) of two image channels were enhanced with the fast digital lock-in algorithm. In order to simultaneously improve the quality of white and fluorescence images obtained by fluorescence endoscope, and improve the SNR to achieve a better image processing effect, two sources of white light and near-infrared light of a fluorescence endoscope were modulated, then the acquired images were demodulated into white and fluorescence images. A fluorescent endoscope experimental platform was setup to acquire endoscopic images of a target dyed by indocyanine green. The experimental results showed that the SNR of white and fluorescent images without the lock-in algorithm were 36.56 dB and 33.47 dB, respectively. However, with the lock-in algorithm, the SNR of white and fluorescent images were 39.54 dB and 35.70 dB, respectively. The SNR of white and fluorescent images was increased by 8.2% and 6.7%, respectively, by appling the digital lock-in algorithm. Therefore, this novel fluorescence endoscope based on the fast digital lock-in algorithm can rapidly and simultaneously obtain two-channel images of white light and fluorescence, effectively enhance the SNR of white and fluorescent images, and improve the imaging quality.
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title_short	Enhancement of signal-to-noise ratio for fluorescence endoscope image based on fast digital lock-in algorithm
url	https://doi.org/10.1098/rsos.200779 https://doaj.org/article/ec5a75c1ae7340bcb479f4bdc58c533b https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.200779 https://doaj.org/toc/2054-5703
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author2	Meng Hu Fang Xia Meng Guo Shengzhao Zhang Zhe Zhao Guang Han Jinhai Wang
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up_date	2024-07-03T15:22:14.411Z
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Enhancement of signal-to-noise ratio for fluorescence endoscope image based on fast digital lock-in algorithm

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