Cynometra cauliflora L.: An indigenous tropical fruit tree in Malaysia bearing essential oils and their biological activities
Cynometra cauliflora L., locally known as “nam-nam” or “katak puru-puru” in Malaysia is belonging to the Fabaceae family. The tree is native to Malaysia and has been used traditionally as folk medicine. Limited works have been conducted on C. cauliflora regarding its chemical composition. In view of...
Ausführliche Beschreibung
Autor*in: |
Benedict Anak Samling [verfasserIn] Zaini Assim [verfasserIn] Woei-Yenn Tong [verfasserIn] Chean-Ring Leong [verfasserIn] Syarifah Ab Rashid [verfasserIn] Nik Nur Syazni Nik Mohamed Kamal [verfasserIn] Musthahimah Muhamad [verfasserIn] Wen-Nee Tan [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2021 |
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Schlagwörter: |
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Übergeordnetes Werk: |
In: Arabian Journal of Chemistry - Elsevier, 2016, 14(2021), 9, Seite 103302- |
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Übergeordnetes Werk: |
volume:14 ; year:2021 ; number:9 ; pages:103302- |
Links: |
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DOI / URN: |
10.1016/j.arabjc.2021.103302 |
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Katalog-ID: |
DOAJ006217257 |
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520 | |a Cynometra cauliflora L., locally known as “nam-nam” or “katak puru-puru” in Malaysia is belonging to the Fabaceae family. The tree is native to Malaysia and has been used traditionally as folk medicine. Limited works have been conducted on C. cauliflora regarding its chemical composition. In view of this, the present study aimed to identify the essential oil (EO) composition of the leaf, twig and fruit of C. cauliflora and evaluate their antioxidant, antimicrobial and cytotoxic activities. EOs obtained from different parts of the tree were analyzed using capillary GC and GC/MS. Twenty-six, seventeen and fifty constituents were identified in the leaf, twig and fruit EOs of C. cauliflora. Results demonstrated the dominance of monoterpenes hydrocarbons in the leaf oil and oxygenated monoterpenes in the twig oil. On the contrary, fruit oil was abundant in oxygenated sesquiterpenes. Different chemical profiles were found in different parts of EOs which have contributed to varied biological activities. Twig oil (IC50 37.12 ± 2.84 µg/mL) showed better antioxidant power than the leaf (IC50 207.17 ± 2.95 µg/mL) and fruit oils (IC50 461.88 ± 12.61 µg/mL) in DPPH assay. Additionally, twig oil inhibited an entire range of microorganisms tested with inhibition zones ranging 10.3 ± 0.4 to 29.7 ± 0.4 mm. The twig oil displayed low MIC and MBC values against Staphylococcus aureus (MIC 125.0 µg/mL; MBC 250.0 µg/mL) and MRSA (MIC 125.0 µg/mL; MBC 250.0 µg/mL). In in vitro MTT assay, twig oil showed anti-proliferative effects against human breast cancer MCF-7 cells. | ||
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10.1016/j.arabjc.2021.103302 doi (DE-627)DOAJ006217257 (DE-599)DOAJd0d012b226984a80bbf31892e5300f31 DE-627 ger DE-627 rakwb eng QD1-999 Benedict Anak Samling verfasserin aut Cynometra cauliflora L.: An indigenous tropical fruit tree in Malaysia bearing essential oils and their biological activities 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Cynometra cauliflora L., locally known as “nam-nam” or “katak puru-puru” in Malaysia is belonging to the Fabaceae family. The tree is native to Malaysia and has been used traditionally as folk medicine. Limited works have been conducted on C. cauliflora regarding its chemical composition. In view of this, the present study aimed to identify the essential oil (EO) composition of the leaf, twig and fruit of C. cauliflora and evaluate their antioxidant, antimicrobial and cytotoxic activities. EOs obtained from different parts of the tree were analyzed using capillary GC and GC/MS. Twenty-six, seventeen and fifty constituents were identified in the leaf, twig and fruit EOs of C. cauliflora. Results demonstrated the dominance of monoterpenes hydrocarbons in the leaf oil and oxygenated monoterpenes in the twig oil. On the contrary, fruit oil was abundant in oxygenated sesquiterpenes. Different chemical profiles were found in different parts of EOs which have contributed to varied biological activities. Twig oil (IC50 37.12 ± 2.84 µg/mL) showed better antioxidant power than the leaf (IC50 207.17 ± 2.95 µg/mL) and fruit oils (IC50 461.88 ± 12.61 µg/mL) in DPPH assay. Additionally, twig oil inhibited an entire range of microorganisms tested with inhibition zones ranging 10.3 ± 0.4 to 29.7 ± 0.4 mm. The twig oil displayed low MIC and MBC values against Staphylococcus aureus (MIC 125.0 µg/mL; MBC 250.0 µg/mL) and MRSA (MIC 125.0 µg/mL; MBC 250.0 µg/mL). In in vitro MTT assay, twig oil showed anti-proliferative effects against human breast cancer MCF-7 cells. Cynometra cauliflora Fabaceae Nam-nam Antimicrobial Antioxidant Cytotoxicity Chemistry Zaini Assim verfasserin aut Woei-Yenn Tong verfasserin aut Chean-Ring Leong verfasserin aut Syarifah Ab Rashid verfasserin aut Nik Nur Syazni Nik Mohamed Kamal verfasserin aut Musthahimah Muhamad verfasserin aut Wen-Nee Tan verfasserin aut In Arabian Journal of Chemistry Elsevier, 2016 14(2021), 9, Seite 103302- (DE-627)609401564 (DE-600)2515214-2 18785352 nnns volume:14 year:2021 number:9 pages:103302- https://doi.org/10.1016/j.arabjc.2021.103302 kostenfrei https://doaj.org/article/d0d012b226984a80bbf31892e5300f31 kostenfrei http://www.sciencedirect.com/science/article/pii/S1878535221003178 kostenfrei https://doaj.org/toc/1878-5352 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 14 2021 9 103302- |
spelling |
10.1016/j.arabjc.2021.103302 doi (DE-627)DOAJ006217257 (DE-599)DOAJd0d012b226984a80bbf31892e5300f31 DE-627 ger DE-627 rakwb eng QD1-999 Benedict Anak Samling verfasserin aut Cynometra cauliflora L.: An indigenous tropical fruit tree in Malaysia bearing essential oils and their biological activities 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Cynometra cauliflora L., locally known as “nam-nam” or “katak puru-puru” in Malaysia is belonging to the Fabaceae family. The tree is native to Malaysia and has been used traditionally as folk medicine. Limited works have been conducted on C. cauliflora regarding its chemical composition. In view of this, the present study aimed to identify the essential oil (EO) composition of the leaf, twig and fruit of C. cauliflora and evaluate their antioxidant, antimicrobial and cytotoxic activities. EOs obtained from different parts of the tree were analyzed using capillary GC and GC/MS. Twenty-six, seventeen and fifty constituents were identified in the leaf, twig and fruit EOs of C. cauliflora. Results demonstrated the dominance of monoterpenes hydrocarbons in the leaf oil and oxygenated monoterpenes in the twig oil. On the contrary, fruit oil was abundant in oxygenated sesquiterpenes. Different chemical profiles were found in different parts of EOs which have contributed to varied biological activities. Twig oil (IC50 37.12 ± 2.84 µg/mL) showed better antioxidant power than the leaf (IC50 207.17 ± 2.95 µg/mL) and fruit oils (IC50 461.88 ± 12.61 µg/mL) in DPPH assay. Additionally, twig oil inhibited an entire range of microorganisms tested with inhibition zones ranging 10.3 ± 0.4 to 29.7 ± 0.4 mm. The twig oil displayed low MIC and MBC values against Staphylococcus aureus (MIC 125.0 µg/mL; MBC 250.0 µg/mL) and MRSA (MIC 125.0 µg/mL; MBC 250.0 µg/mL). In in vitro MTT assay, twig oil showed anti-proliferative effects against human breast cancer MCF-7 cells. Cynometra cauliflora Fabaceae Nam-nam Antimicrobial Antioxidant Cytotoxicity Chemistry Zaini Assim verfasserin aut Woei-Yenn Tong verfasserin aut Chean-Ring Leong verfasserin aut Syarifah Ab Rashid verfasserin aut Nik Nur Syazni Nik Mohamed Kamal verfasserin aut Musthahimah Muhamad verfasserin aut Wen-Nee Tan verfasserin aut In Arabian Journal of Chemistry Elsevier, 2016 14(2021), 9, Seite 103302- (DE-627)609401564 (DE-600)2515214-2 18785352 nnns volume:14 year:2021 number:9 pages:103302- https://doi.org/10.1016/j.arabjc.2021.103302 kostenfrei https://doaj.org/article/d0d012b226984a80bbf31892e5300f31 kostenfrei http://www.sciencedirect.com/science/article/pii/S1878535221003178 kostenfrei https://doaj.org/toc/1878-5352 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 14 2021 9 103302- |
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10.1016/j.arabjc.2021.103302 doi (DE-627)DOAJ006217257 (DE-599)DOAJd0d012b226984a80bbf31892e5300f31 DE-627 ger DE-627 rakwb eng QD1-999 Benedict Anak Samling verfasserin aut Cynometra cauliflora L.: An indigenous tropical fruit tree in Malaysia bearing essential oils and their biological activities 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Cynometra cauliflora L., locally known as “nam-nam” or “katak puru-puru” in Malaysia is belonging to the Fabaceae family. The tree is native to Malaysia and has been used traditionally as folk medicine. Limited works have been conducted on C. cauliflora regarding its chemical composition. In view of this, the present study aimed to identify the essential oil (EO) composition of the leaf, twig and fruit of C. cauliflora and evaluate their antioxidant, antimicrobial and cytotoxic activities. EOs obtained from different parts of the tree were analyzed using capillary GC and GC/MS. Twenty-six, seventeen and fifty constituents were identified in the leaf, twig and fruit EOs of C. cauliflora. Results demonstrated the dominance of monoterpenes hydrocarbons in the leaf oil and oxygenated monoterpenes in the twig oil. On the contrary, fruit oil was abundant in oxygenated sesquiterpenes. Different chemical profiles were found in different parts of EOs which have contributed to varied biological activities. Twig oil (IC50 37.12 ± 2.84 µg/mL) showed better antioxidant power than the leaf (IC50 207.17 ± 2.95 µg/mL) and fruit oils (IC50 461.88 ± 12.61 µg/mL) in DPPH assay. Additionally, twig oil inhibited an entire range of microorganisms tested with inhibition zones ranging 10.3 ± 0.4 to 29.7 ± 0.4 mm. The twig oil displayed low MIC and MBC values against Staphylococcus aureus (MIC 125.0 µg/mL; MBC 250.0 µg/mL) and MRSA (MIC 125.0 µg/mL; MBC 250.0 µg/mL). In in vitro MTT assay, twig oil showed anti-proliferative effects against human breast cancer MCF-7 cells. Cynometra cauliflora Fabaceae Nam-nam Antimicrobial Antioxidant Cytotoxicity Chemistry Zaini Assim verfasserin aut Woei-Yenn Tong verfasserin aut Chean-Ring Leong verfasserin aut Syarifah Ab Rashid verfasserin aut Nik Nur Syazni Nik Mohamed Kamal verfasserin aut Musthahimah Muhamad verfasserin aut Wen-Nee Tan verfasserin aut In Arabian Journal of Chemistry Elsevier, 2016 14(2021), 9, Seite 103302- (DE-627)609401564 (DE-600)2515214-2 18785352 nnns volume:14 year:2021 number:9 pages:103302- https://doi.org/10.1016/j.arabjc.2021.103302 kostenfrei https://doaj.org/article/d0d012b226984a80bbf31892e5300f31 kostenfrei http://www.sciencedirect.com/science/article/pii/S1878535221003178 kostenfrei https://doaj.org/toc/1878-5352 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 14 2021 9 103302- |
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10.1016/j.arabjc.2021.103302 doi (DE-627)DOAJ006217257 (DE-599)DOAJd0d012b226984a80bbf31892e5300f31 DE-627 ger DE-627 rakwb eng QD1-999 Benedict Anak Samling verfasserin aut Cynometra cauliflora L.: An indigenous tropical fruit tree in Malaysia bearing essential oils and their biological activities 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Cynometra cauliflora L., locally known as “nam-nam” or “katak puru-puru” in Malaysia is belonging to the Fabaceae family. The tree is native to Malaysia and has been used traditionally as folk medicine. Limited works have been conducted on C. cauliflora regarding its chemical composition. In view of this, the present study aimed to identify the essential oil (EO) composition of the leaf, twig and fruit of C. cauliflora and evaluate their antioxidant, antimicrobial and cytotoxic activities. EOs obtained from different parts of the tree were analyzed using capillary GC and GC/MS. Twenty-six, seventeen and fifty constituents were identified in the leaf, twig and fruit EOs of C. cauliflora. Results demonstrated the dominance of monoterpenes hydrocarbons in the leaf oil and oxygenated monoterpenes in the twig oil. On the contrary, fruit oil was abundant in oxygenated sesquiterpenes. Different chemical profiles were found in different parts of EOs which have contributed to varied biological activities. Twig oil (IC50 37.12 ± 2.84 µg/mL) showed better antioxidant power than the leaf (IC50 207.17 ± 2.95 µg/mL) and fruit oils (IC50 461.88 ± 12.61 µg/mL) in DPPH assay. Additionally, twig oil inhibited an entire range of microorganisms tested with inhibition zones ranging 10.3 ± 0.4 to 29.7 ± 0.4 mm. The twig oil displayed low MIC and MBC values against Staphylococcus aureus (MIC 125.0 µg/mL; MBC 250.0 µg/mL) and MRSA (MIC 125.0 µg/mL; MBC 250.0 µg/mL). In in vitro MTT assay, twig oil showed anti-proliferative effects against human breast cancer MCF-7 cells. Cynometra cauliflora Fabaceae Nam-nam Antimicrobial Antioxidant Cytotoxicity Chemistry Zaini Assim verfasserin aut Woei-Yenn Tong verfasserin aut Chean-Ring Leong verfasserin aut Syarifah Ab Rashid verfasserin aut Nik Nur Syazni Nik Mohamed Kamal verfasserin aut Musthahimah Muhamad verfasserin aut Wen-Nee Tan verfasserin aut In Arabian Journal of Chemistry Elsevier, 2016 14(2021), 9, Seite 103302- (DE-627)609401564 (DE-600)2515214-2 18785352 nnns volume:14 year:2021 number:9 pages:103302- https://doi.org/10.1016/j.arabjc.2021.103302 kostenfrei https://doaj.org/article/d0d012b226984a80bbf31892e5300f31 kostenfrei http://www.sciencedirect.com/science/article/pii/S1878535221003178 kostenfrei https://doaj.org/toc/1878-5352 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 14 2021 9 103302- |
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10.1016/j.arabjc.2021.103302 doi (DE-627)DOAJ006217257 (DE-599)DOAJd0d012b226984a80bbf31892e5300f31 DE-627 ger DE-627 rakwb eng QD1-999 Benedict Anak Samling verfasserin aut Cynometra cauliflora L.: An indigenous tropical fruit tree in Malaysia bearing essential oils and their biological activities 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Cynometra cauliflora L., locally known as “nam-nam” or “katak puru-puru” in Malaysia is belonging to the Fabaceae family. The tree is native to Malaysia and has been used traditionally as folk medicine. Limited works have been conducted on C. cauliflora regarding its chemical composition. In view of this, the present study aimed to identify the essential oil (EO) composition of the leaf, twig and fruit of C. cauliflora and evaluate their antioxidant, antimicrobial and cytotoxic activities. EOs obtained from different parts of the tree were analyzed using capillary GC and GC/MS. Twenty-six, seventeen and fifty constituents were identified in the leaf, twig and fruit EOs of C. cauliflora. Results demonstrated the dominance of monoterpenes hydrocarbons in the leaf oil and oxygenated monoterpenes in the twig oil. On the contrary, fruit oil was abundant in oxygenated sesquiterpenes. Different chemical profiles were found in different parts of EOs which have contributed to varied biological activities. Twig oil (IC50 37.12 ± 2.84 µg/mL) showed better antioxidant power than the leaf (IC50 207.17 ± 2.95 µg/mL) and fruit oils (IC50 461.88 ± 12.61 µg/mL) in DPPH assay. Additionally, twig oil inhibited an entire range of microorganisms tested with inhibition zones ranging 10.3 ± 0.4 to 29.7 ± 0.4 mm. The twig oil displayed low MIC and MBC values against Staphylococcus aureus (MIC 125.0 µg/mL; MBC 250.0 µg/mL) and MRSA (MIC 125.0 µg/mL; MBC 250.0 µg/mL). In in vitro MTT assay, twig oil showed anti-proliferative effects against human breast cancer MCF-7 cells. Cynometra cauliflora Fabaceae Nam-nam Antimicrobial Antioxidant Cytotoxicity Chemistry Zaini Assim verfasserin aut Woei-Yenn Tong verfasserin aut Chean-Ring Leong verfasserin aut Syarifah Ab Rashid verfasserin aut Nik Nur Syazni Nik Mohamed Kamal verfasserin aut Musthahimah Muhamad verfasserin aut Wen-Nee Tan verfasserin aut In Arabian Journal of Chemistry Elsevier, 2016 14(2021), 9, Seite 103302- (DE-627)609401564 (DE-600)2515214-2 18785352 nnns volume:14 year:2021 number:9 pages:103302- https://doi.org/10.1016/j.arabjc.2021.103302 kostenfrei https://doaj.org/article/d0d012b226984a80bbf31892e5300f31 kostenfrei http://www.sciencedirect.com/science/article/pii/S1878535221003178 kostenfrei https://doaj.org/toc/1878-5352 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 14 2021 9 103302- |
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cynometra cauliflora l.: an indigenous tropical fruit tree in malaysia bearing essential oils and their biological activities |
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Cynometra cauliflora L.: An indigenous tropical fruit tree in Malaysia bearing essential oils and their biological activities |
abstract |
Cynometra cauliflora L., locally known as “nam-nam” or “katak puru-puru” in Malaysia is belonging to the Fabaceae family. The tree is native to Malaysia and has been used traditionally as folk medicine. Limited works have been conducted on C. cauliflora regarding its chemical composition. In view of this, the present study aimed to identify the essential oil (EO) composition of the leaf, twig and fruit of C. cauliflora and evaluate their antioxidant, antimicrobial and cytotoxic activities. EOs obtained from different parts of the tree were analyzed using capillary GC and GC/MS. Twenty-six, seventeen and fifty constituents were identified in the leaf, twig and fruit EOs of C. cauliflora. Results demonstrated the dominance of monoterpenes hydrocarbons in the leaf oil and oxygenated monoterpenes in the twig oil. On the contrary, fruit oil was abundant in oxygenated sesquiterpenes. Different chemical profiles were found in different parts of EOs which have contributed to varied biological activities. Twig oil (IC50 37.12 ± 2.84 µg/mL) showed better antioxidant power than the leaf (IC50 207.17 ± 2.95 µg/mL) and fruit oils (IC50 461.88 ± 12.61 µg/mL) in DPPH assay. Additionally, twig oil inhibited an entire range of microorganisms tested with inhibition zones ranging 10.3 ± 0.4 to 29.7 ± 0.4 mm. The twig oil displayed low MIC and MBC values against Staphylococcus aureus (MIC 125.0 µg/mL; MBC 250.0 µg/mL) and MRSA (MIC 125.0 µg/mL; MBC 250.0 µg/mL). In in vitro MTT assay, twig oil showed anti-proliferative effects against human breast cancer MCF-7 cells. |
abstractGer |
Cynometra cauliflora L., locally known as “nam-nam” or “katak puru-puru” in Malaysia is belonging to the Fabaceae family. The tree is native to Malaysia and has been used traditionally as folk medicine. Limited works have been conducted on C. cauliflora regarding its chemical composition. In view of this, the present study aimed to identify the essential oil (EO) composition of the leaf, twig and fruit of C. cauliflora and evaluate their antioxidant, antimicrobial and cytotoxic activities. EOs obtained from different parts of the tree were analyzed using capillary GC and GC/MS. Twenty-six, seventeen and fifty constituents were identified in the leaf, twig and fruit EOs of C. cauliflora. Results demonstrated the dominance of monoterpenes hydrocarbons in the leaf oil and oxygenated monoterpenes in the twig oil. On the contrary, fruit oil was abundant in oxygenated sesquiterpenes. Different chemical profiles were found in different parts of EOs which have contributed to varied biological activities. Twig oil (IC50 37.12 ± 2.84 µg/mL) showed better antioxidant power than the leaf (IC50 207.17 ± 2.95 µg/mL) and fruit oils (IC50 461.88 ± 12.61 µg/mL) in DPPH assay. Additionally, twig oil inhibited an entire range of microorganisms tested with inhibition zones ranging 10.3 ± 0.4 to 29.7 ± 0.4 mm. The twig oil displayed low MIC and MBC values against Staphylococcus aureus (MIC 125.0 µg/mL; MBC 250.0 µg/mL) and MRSA (MIC 125.0 µg/mL; MBC 250.0 µg/mL). In in vitro MTT assay, twig oil showed anti-proliferative effects against human breast cancer MCF-7 cells. |
abstract_unstemmed |
Cynometra cauliflora L., locally known as “nam-nam” or “katak puru-puru” in Malaysia is belonging to the Fabaceae family. The tree is native to Malaysia and has been used traditionally as folk medicine. Limited works have been conducted on C. cauliflora regarding its chemical composition. In view of this, the present study aimed to identify the essential oil (EO) composition of the leaf, twig and fruit of C. cauliflora and evaluate their antioxidant, antimicrobial and cytotoxic activities. EOs obtained from different parts of the tree were analyzed using capillary GC and GC/MS. Twenty-six, seventeen and fifty constituents were identified in the leaf, twig and fruit EOs of C. cauliflora. Results demonstrated the dominance of monoterpenes hydrocarbons in the leaf oil and oxygenated monoterpenes in the twig oil. On the contrary, fruit oil was abundant in oxygenated sesquiterpenes. Different chemical profiles were found in different parts of EOs which have contributed to varied biological activities. Twig oil (IC50 37.12 ± 2.84 µg/mL) showed better antioxidant power than the leaf (IC50 207.17 ± 2.95 µg/mL) and fruit oils (IC50 461.88 ± 12.61 µg/mL) in DPPH assay. Additionally, twig oil inhibited an entire range of microorganisms tested with inhibition zones ranging 10.3 ± 0.4 to 29.7 ± 0.4 mm. The twig oil displayed low MIC and MBC values against Staphylococcus aureus (MIC 125.0 µg/mL; MBC 250.0 µg/mL) and MRSA (MIC 125.0 µg/mL; MBC 250.0 µg/mL). In in vitro MTT assay, twig oil showed anti-proliferative effects against human breast cancer MCF-7 cells. |
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Cynometra cauliflora L.: An indigenous tropical fruit tree in Malaysia bearing essential oils and their biological activities |
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Twig oil (IC50 37.12 ± 2.84 µg/mL) showed better antioxidant power than the leaf (IC50 207.17 ± 2.95 µg/mL) and fruit oils (IC50 461.88 ± 12.61 µg/mL) in DPPH assay. Additionally, twig oil inhibited an entire range of microorganisms tested with inhibition zones ranging 10.3 ± 0.4 to 29.7 ± 0.4 mm. The twig oil displayed low MIC and MBC values against Staphylococcus aureus (MIC 125.0 µg/mL; MBC 250.0 µg/mL) and MRSA (MIC 125.0 µg/mL; MBC 250.0 µg/mL). 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