Resveratrol and SIRT1: Antiaging Cornerstones for Oocytes?

It is well-known that there is an enormous variability in the aging-related decline of oocytes’ quantity and their developmental competence among mammalian species. The implication of female germline aging is profound from the perspective of evolutionary conservation of the aging mechanism, a topic...
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Gespeichert in:

Autor*in:	Arkadiusz Grzeczka [verfasserIn] Paweł Kordowitzki [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	sirtuins SIRT1 oocyte maturation resveratrol metaphase II aging

Übergeordnetes Werk:	In: Nutrients - MDPI AG, 2009, 14(2022), 23, p 5101
Übergeordnetes Werk:	volume:14 ; year:2022 ; number:23, p 5101

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/nu14235101

Katalog-ID:	DOAJ006696864

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spelling	10.3390/nu14235101 doi (DE-627)DOAJ006696864 (DE-599)DOAJ3f783d6921d34244becf5c8a2771f76f DE-627 ger DE-627 rakwb eng TX341-641 Arkadiusz Grzeczka verfasserin aut Resveratrol and SIRT1: Antiaging Cornerstones for Oocytes? 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier It is well-known that there is an enormous variability in the aging-related decline of oocytes’ quantity and their developmental competence among mammalian species. The implication of female germline aging is profound from the perspective of evolutionary conservation of the aging mechanism, a topic of continuous and widespread interest that has yet to be fully addressed for the mammalian oocyte. There is a certain need to develop novel antiaging strategies to delay or slow down aging, or even to reverse the aging phenotype in the oocyte. In the past two decades, several antioxidants have been tested for this purpose. Resveratrol is one of these latter-mentioned compounds, which has shown anti-inflammatory and antiaging properties in a dose-dependent manner. Interestingly, resveratrol appears to enhance the activity of so-called Sirtuin 1, too. Therefore, the aim of this review is to summarize and discuss the latest findings related to resveratrol, Sirtuin 1, and their crosstalk and influence on the mammalian oocyte to elucidate the question of whether these factors can delay or slow down reproductive aging. sirtuins SIRT1 oocyte maturation resveratrol metaphase II aging Nutrition. Foods and food supply Paweł Kordowitzki verfasserin aut In Nutrients MDPI AG, 2009 14(2022), 23, p 5101 (DE-627)610604155 (DE-600)2518386-2 20726643 nnns volume:14 year:2022 number:23, p 5101 https://doi.org/10.3390/nu14235101 kostenfrei https://doaj.org/article/3f783d6921d34244becf5c8a2771f76f kostenfrei https://www.mdpi.com/2072-6643/14/23/5101 kostenfrei https://doaj.org/toc/2072-6643 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2022 23, p 5101
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allfieldsGer	10.3390/nu14235101 doi (DE-627)DOAJ006696864 (DE-599)DOAJ3f783d6921d34244becf5c8a2771f76f DE-627 ger DE-627 rakwb eng TX341-641 Arkadiusz Grzeczka verfasserin aut Resveratrol and SIRT1: Antiaging Cornerstones for Oocytes? 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier It is well-known that there is an enormous variability in the aging-related decline of oocytes’ quantity and their developmental competence among mammalian species. The implication of female germline aging is profound from the perspective of evolutionary conservation of the aging mechanism, a topic of continuous and widespread interest that has yet to be fully addressed for the mammalian oocyte. There is a certain need to develop novel antiaging strategies to delay or slow down aging, or even to reverse the aging phenotype in the oocyte. In the past two decades, several antioxidants have been tested for this purpose. Resveratrol is one of these latter-mentioned compounds, which has shown anti-inflammatory and antiaging properties in a dose-dependent manner. Interestingly, resveratrol appears to enhance the activity of so-called Sirtuin 1, too. Therefore, the aim of this review is to summarize and discuss the latest findings related to resveratrol, Sirtuin 1, and their crosstalk and influence on the mammalian oocyte to elucidate the question of whether these factors can delay or slow down reproductive aging. sirtuins SIRT1 oocyte maturation resveratrol metaphase II aging Nutrition. Foods and food supply Paweł Kordowitzki verfasserin aut In Nutrients MDPI AG, 2009 14(2022), 23, p 5101 (DE-627)610604155 (DE-600)2518386-2 20726643 nnns volume:14 year:2022 number:23, p 5101 https://doi.org/10.3390/nu14235101 kostenfrei https://doaj.org/article/3f783d6921d34244becf5c8a2771f76f kostenfrei https://www.mdpi.com/2072-6643/14/23/5101 kostenfrei https://doaj.org/toc/2072-6643 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2022 23, p 5101
allfieldsSound	10.3390/nu14235101 doi (DE-627)DOAJ006696864 (DE-599)DOAJ3f783d6921d34244becf5c8a2771f76f DE-627 ger DE-627 rakwb eng TX341-641 Arkadiusz Grzeczka verfasserin aut Resveratrol and SIRT1: Antiaging Cornerstones for Oocytes? 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier It is well-known that there is an enormous variability in the aging-related decline of oocytes’ quantity and their developmental competence among mammalian species. The implication of female germline aging is profound from the perspective of evolutionary conservation of the aging mechanism, a topic of continuous and widespread interest that has yet to be fully addressed for the mammalian oocyte. There is a certain need to develop novel antiaging strategies to delay or slow down aging, or even to reverse the aging phenotype in the oocyte. In the past two decades, several antioxidants have been tested for this purpose. Resveratrol is one of these latter-mentioned compounds, which has shown anti-inflammatory and antiaging properties in a dose-dependent manner. Interestingly, resveratrol appears to enhance the activity of so-called Sirtuin 1, too. Therefore, the aim of this review is to summarize and discuss the latest findings related to resveratrol, Sirtuin 1, and their crosstalk and influence on the mammalian oocyte to elucidate the question of whether these factors can delay or slow down reproductive aging. sirtuins SIRT1 oocyte maturation resveratrol metaphase II aging Nutrition. Foods and food supply Paweł Kordowitzki verfasserin aut In Nutrients MDPI AG, 2009 14(2022), 23, p 5101 (DE-627)610604155 (DE-600)2518386-2 20726643 nnns volume:14 year:2022 number:23, p 5101 https://doi.org/10.3390/nu14235101 kostenfrei https://doaj.org/article/3f783d6921d34244becf5c8a2771f76f kostenfrei https://www.mdpi.com/2072-6643/14/23/5101 kostenfrei https://doaj.org/toc/2072-6643 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2022 23, p 5101
language	English
source	In Nutrients 14(2022), 23, p 5101 volume:14 year:2022 number:23, p 5101
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topic_facet	sirtuins SIRT1 oocyte maturation resveratrol metaphase II aging Nutrition. Foods and food supply
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container_title	Nutrients
authorswithroles_txt_mv	Arkadiusz Grzeczka @@aut@@ Paweł Kordowitzki @@aut@@
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author	Arkadiusz Grzeczka
spellingShingle	Arkadiusz Grzeczka misc TX341-641 misc sirtuins misc SIRT1 misc oocyte maturation misc resveratrol misc metaphase II misc aging misc Nutrition. Foods and food supply Resveratrol and SIRT1: Antiaging Cornerstones for Oocytes?
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topic_title	TX341-641 Resveratrol and SIRT1: Antiaging Cornerstones for Oocytes? sirtuins SIRT1 oocyte maturation resveratrol metaphase II aging
topic	misc TX341-641 misc sirtuins misc SIRT1 misc oocyte maturation misc resveratrol misc metaphase II misc aging misc Nutrition. Foods and food supply
topic_unstemmed	misc TX341-641 misc sirtuins misc SIRT1 misc oocyte maturation misc resveratrol misc metaphase II misc aging misc Nutrition. Foods and food supply
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title	Resveratrol and SIRT1: Antiaging Cornerstones for Oocytes?
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title_sort	resveratrol and sirt1: antiaging cornerstones for oocytes?
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title_auth	Resveratrol and SIRT1: Antiaging Cornerstones for Oocytes?
abstract	It is well-known that there is an enormous variability in the aging-related decline of oocytes’ quantity and their developmental competence among mammalian species. The implication of female germline aging is profound from the perspective of evolutionary conservation of the aging mechanism, a topic of continuous and widespread interest that has yet to be fully addressed for the mammalian oocyte. There is a certain need to develop novel antiaging strategies to delay or slow down aging, or even to reverse the aging phenotype in the oocyte. In the past two decades, several antioxidants have been tested for this purpose. Resveratrol is one of these latter-mentioned compounds, which has shown anti-inflammatory and antiaging properties in a dose-dependent manner. Interestingly, resveratrol appears to enhance the activity of so-called Sirtuin 1, too. Therefore, the aim of this review is to summarize and discuss the latest findings related to resveratrol, Sirtuin 1, and their crosstalk and influence on the mammalian oocyte to elucidate the question of whether these factors can delay or slow down reproductive aging.
abstractGer	It is well-known that there is an enormous variability in the aging-related decline of oocytes’ quantity and their developmental competence among mammalian species. The implication of female germline aging is profound from the perspective of evolutionary conservation of the aging mechanism, a topic of continuous and widespread interest that has yet to be fully addressed for the mammalian oocyte. There is a certain need to develop novel antiaging strategies to delay or slow down aging, or even to reverse the aging phenotype in the oocyte. In the past two decades, several antioxidants have been tested for this purpose. Resveratrol is one of these latter-mentioned compounds, which has shown anti-inflammatory and antiaging properties in a dose-dependent manner. Interestingly, resveratrol appears to enhance the activity of so-called Sirtuin 1, too. Therefore, the aim of this review is to summarize and discuss the latest findings related to resveratrol, Sirtuin 1, and their crosstalk and influence on the mammalian oocyte to elucidate the question of whether these factors can delay or slow down reproductive aging.
abstract_unstemmed	It is well-known that there is an enormous variability in the aging-related decline of oocytes’ quantity and their developmental competence among mammalian species. The implication of female germline aging is profound from the perspective of evolutionary conservation of the aging mechanism, a topic of continuous and widespread interest that has yet to be fully addressed for the mammalian oocyte. There is a certain need to develop novel antiaging strategies to delay or slow down aging, or even to reverse the aging phenotype in the oocyte. In the past two decades, several antioxidants have been tested for this purpose. Resveratrol is one of these latter-mentioned compounds, which has shown anti-inflammatory and antiaging properties in a dose-dependent manner. Interestingly, resveratrol appears to enhance the activity of so-called Sirtuin 1, too. Therefore, the aim of this review is to summarize and discuss the latest findings related to resveratrol, Sirtuin 1, and their crosstalk and influence on the mammalian oocyte to elucidate the question of whether these factors can delay or slow down reproductive aging.
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title_short	Resveratrol and SIRT1: Antiaging Cornerstones for Oocytes?
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