Behçet's disease: Clinical and demographic associations
AIM: To comparatively study the clinical manifestations, sexual and HLA-B51 associations in patients with Behçet's disease (BD) in two ethnic groups/MATERIAL AND METHODS: The authors examined 143 patients with the valid diagnosis of BD who were divided into 2 groups: 1) 85 patients, the dweller...
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| Autor*in: |
Z S Alekberova [verfasserIn] F I Izmailova [verfasserIn] M T Kudaev [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Russisch |
| Erschienen: |
2013 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
In: Терапевтический архив - "Consilium Medicum" Publishing house, 2018, 85(2013), 5, Seite 48-52 |
|---|---|
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volume:85 ; year:2013 ; number:5 ; pages:48-52 |
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DOAJ007792751 |
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| 520 | |a AIM: To comparatively study the clinical manifestations, sexual and HLA-B51 associations in patients with Behçet's disease (BD) in two ethnic groups/MATERIAL AND METHODS: The authors examined 143 patients with the valid diagnosis of BD who were divided into 2 groups: 1) 85 patients, the dwellers of Dagestan (a multiethnic cohort), 63 men and 22 women (mean age 29±7.4 years); 2) 58 Russian men and women (mean age 33±11.7 years)/RESULTS: Two major criteria for BD, such as aphthous stomatitis and external genital ulcers, were found with the same frequency. Panuveitis and angiitis of the retina were diagnosed more frequently in the Dagestani population with BD than in the Russians. Out of the minor criteria for BD, the incidence of lower limb deep venous thrombosis was 23% for the Dagestanis versus 3% for the Russians. Arterial thromboses and pulmonary artery aneurysms became causes of death in 4 in 5 men aged 19-23 years from their Dagestani ancestry. HLA B51 (B marker) was found in the dwellers of Dagestan: in 70% of the men and 40% of the women who had BD/CONCLUSION: BD runs a more severe course in male patients and is characterized by severe eye diseases and the systematic pattern of the process at young age. Gender-specific and genetic aspects call for further comparative investigations on large ethnic patient cohorts of other ancestries. | ||
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(DE-627)DOAJ007792751 (DE-599)DOAJ493c22916cf342378159d3bd6f27213a DE-627 ger DE-627 rakwb rus Z S Alekberova verfasserin aut Behçet's disease: Clinical and demographic associations 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier AIM: To comparatively study the clinical manifestations, sexual and HLA-B51 associations in patients with Behçet's disease (BD) in two ethnic groups/MATERIAL AND METHODS: The authors examined 143 patients with the valid diagnosis of BD who were divided into 2 groups: 1) 85 patients, the dwellers of Dagestan (a multiethnic cohort), 63 men and 22 women (mean age 29±7.4 years); 2) 58 Russian men and women (mean age 33±11.7 years)/RESULTS: Two major criteria for BD, such as aphthous stomatitis and external genital ulcers, were found with the same frequency. Panuveitis and angiitis of the retina were diagnosed more frequently in the Dagestani population with BD than in the Russians. Out of the minor criteria for BD, the incidence of lower limb deep venous thrombosis was 23% for the Dagestanis versus 3% for the Russians. Arterial thromboses and pulmonary artery aneurysms became causes of death in 4 in 5 men aged 19-23 years from their Dagestani ancestry. HLA B51 (B marker) was found in the dwellers of Dagestan: in 70% of the men and 40% of the women who had BD/CONCLUSION: BD runs a more severe course in male patients and is characterized by severe eye diseases and the systematic pattern of the process at young age. Gender-specific and genetic aspects call for further comparative investigations on large ethnic patient cohorts of other ancestries. behçet's disease ethnicity demographic indicators clinical polymorphism hla-b51 Medicine R F I Izmailova verfasserin aut M T Kudaev verfasserin aut In Терапевтический архив "Consilium Medicum" Publishing house, 2018 85(2013), 5, Seite 48-52 (DE-627)1760620270 23095342 nnns volume:85 year:2013 number:5 pages:48-52 https://doaj.org/article/493c22916cf342378159d3bd6f27213a kostenfrei https://ter-arkhiv.ru/0040-3660/article/view/31277 kostenfrei https://doaj.org/toc/0040-3660 Journal toc kostenfrei https://doaj.org/toc/2309-5342 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA AR 85 2013 5 48-52 |
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(DE-627)DOAJ007792751 (DE-599)DOAJ493c22916cf342378159d3bd6f27213a DE-627 ger DE-627 rakwb rus Z S Alekberova verfasserin aut Behçet's disease: Clinical and demographic associations 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier AIM: To comparatively study the clinical manifestations, sexual and HLA-B51 associations in patients with Behçet's disease (BD) in two ethnic groups/MATERIAL AND METHODS: The authors examined 143 patients with the valid diagnosis of BD who were divided into 2 groups: 1) 85 patients, the dwellers of Dagestan (a multiethnic cohort), 63 men and 22 women (mean age 29±7.4 years); 2) 58 Russian men and women (mean age 33±11.7 years)/RESULTS: Two major criteria for BD, such as aphthous stomatitis and external genital ulcers, were found with the same frequency. Panuveitis and angiitis of the retina were diagnosed more frequently in the Dagestani population with BD than in the Russians. Out of the minor criteria for BD, the incidence of lower limb deep venous thrombosis was 23% for the Dagestanis versus 3% for the Russians. Arterial thromboses and pulmonary artery aneurysms became causes of death in 4 in 5 men aged 19-23 years from their Dagestani ancestry. HLA B51 (B marker) was found in the dwellers of Dagestan: in 70% of the men and 40% of the women who had BD/CONCLUSION: BD runs a more severe course in male patients and is characterized by severe eye diseases and the systematic pattern of the process at young age. Gender-specific and genetic aspects call for further comparative investigations on large ethnic patient cohorts of other ancestries. behçet's disease ethnicity demographic indicators clinical polymorphism hla-b51 Medicine R F I Izmailova verfasserin aut M T Kudaev verfasserin aut In Терапевтический архив "Consilium Medicum" Publishing house, 2018 85(2013), 5, Seite 48-52 (DE-627)1760620270 23095342 nnns volume:85 year:2013 number:5 pages:48-52 https://doaj.org/article/493c22916cf342378159d3bd6f27213a kostenfrei https://ter-arkhiv.ru/0040-3660/article/view/31277 kostenfrei https://doaj.org/toc/0040-3660 Journal toc kostenfrei https://doaj.org/toc/2309-5342 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA AR 85 2013 5 48-52 |
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(DE-627)DOAJ007792751 (DE-599)DOAJ493c22916cf342378159d3bd6f27213a DE-627 ger DE-627 rakwb rus Z S Alekberova verfasserin aut Behçet's disease: Clinical and demographic associations 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier AIM: To comparatively study the clinical manifestations, sexual and HLA-B51 associations in patients with Behçet's disease (BD) in two ethnic groups/MATERIAL AND METHODS: The authors examined 143 patients with the valid diagnosis of BD who were divided into 2 groups: 1) 85 patients, the dwellers of Dagestan (a multiethnic cohort), 63 men and 22 women (mean age 29±7.4 years); 2) 58 Russian men and women (mean age 33±11.7 years)/RESULTS: Two major criteria for BD, such as aphthous stomatitis and external genital ulcers, were found with the same frequency. Panuveitis and angiitis of the retina were diagnosed more frequently in the Dagestani population with BD than in the Russians. Out of the minor criteria for BD, the incidence of lower limb deep venous thrombosis was 23% for the Dagestanis versus 3% for the Russians. Arterial thromboses and pulmonary artery aneurysms became causes of death in 4 in 5 men aged 19-23 years from their Dagestani ancestry. HLA B51 (B marker) was found in the dwellers of Dagestan: in 70% of the men and 40% of the women who had BD/CONCLUSION: BD runs a more severe course in male patients and is characterized by severe eye diseases and the systematic pattern of the process at young age. Gender-specific and genetic aspects call for further comparative investigations on large ethnic patient cohorts of other ancestries. behçet's disease ethnicity demographic indicators clinical polymorphism hla-b51 Medicine R F I Izmailova verfasserin aut M T Kudaev verfasserin aut In Терапевтический архив "Consilium Medicum" Publishing house, 2018 85(2013), 5, Seite 48-52 (DE-627)1760620270 23095342 nnns volume:85 year:2013 number:5 pages:48-52 https://doaj.org/article/493c22916cf342378159d3bd6f27213a kostenfrei https://ter-arkhiv.ru/0040-3660/article/view/31277 kostenfrei https://doaj.org/toc/0040-3660 Journal toc kostenfrei https://doaj.org/toc/2309-5342 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA AR 85 2013 5 48-52 |
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(DE-627)DOAJ007792751 (DE-599)DOAJ493c22916cf342378159d3bd6f27213a DE-627 ger DE-627 rakwb rus Z S Alekberova verfasserin aut Behçet's disease: Clinical and demographic associations 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier AIM: To comparatively study the clinical manifestations, sexual and HLA-B51 associations in patients with Behçet's disease (BD) in two ethnic groups/MATERIAL AND METHODS: The authors examined 143 patients with the valid diagnosis of BD who were divided into 2 groups: 1) 85 patients, the dwellers of Dagestan (a multiethnic cohort), 63 men and 22 women (mean age 29±7.4 years); 2) 58 Russian men and women (mean age 33±11.7 years)/RESULTS: Two major criteria for BD, such as aphthous stomatitis and external genital ulcers, were found with the same frequency. Panuveitis and angiitis of the retina were diagnosed more frequently in the Dagestani population with BD than in the Russians. Out of the minor criteria for BD, the incidence of lower limb deep venous thrombosis was 23% for the Dagestanis versus 3% for the Russians. Arterial thromboses and pulmonary artery aneurysms became causes of death in 4 in 5 men aged 19-23 years from their Dagestani ancestry. HLA B51 (B marker) was found in the dwellers of Dagestan: in 70% of the men and 40% of the women who had BD/CONCLUSION: BD runs a more severe course in male patients and is characterized by severe eye diseases and the systematic pattern of the process at young age. Gender-specific and genetic aspects call for further comparative investigations on large ethnic patient cohorts of other ancestries. behçet's disease ethnicity demographic indicators clinical polymorphism hla-b51 Medicine R F I Izmailova verfasserin aut M T Kudaev verfasserin aut In Терапевтический архив "Consilium Medicum" Publishing house, 2018 85(2013), 5, Seite 48-52 (DE-627)1760620270 23095342 nnns volume:85 year:2013 number:5 pages:48-52 https://doaj.org/article/493c22916cf342378159d3bd6f27213a kostenfrei https://ter-arkhiv.ru/0040-3660/article/view/31277 kostenfrei https://doaj.org/toc/0040-3660 Journal toc kostenfrei https://doaj.org/toc/2309-5342 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA AR 85 2013 5 48-52 |
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(DE-627)DOAJ007792751 (DE-599)DOAJ493c22916cf342378159d3bd6f27213a DE-627 ger DE-627 rakwb rus Z S Alekberova verfasserin aut Behçet's disease: Clinical and demographic associations 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier AIM: To comparatively study the clinical manifestations, sexual and HLA-B51 associations in patients with Behçet's disease (BD) in two ethnic groups/MATERIAL AND METHODS: The authors examined 143 patients with the valid diagnosis of BD who were divided into 2 groups: 1) 85 patients, the dwellers of Dagestan (a multiethnic cohort), 63 men and 22 women (mean age 29±7.4 years); 2) 58 Russian men and women (mean age 33±11.7 years)/RESULTS: Two major criteria for BD, such as aphthous stomatitis and external genital ulcers, were found with the same frequency. Panuveitis and angiitis of the retina were diagnosed more frequently in the Dagestani population with BD than in the Russians. Out of the minor criteria for BD, the incidence of lower limb deep venous thrombosis was 23% for the Dagestanis versus 3% for the Russians. Arterial thromboses and pulmonary artery aneurysms became causes of death in 4 in 5 men aged 19-23 years from their Dagestani ancestry. HLA B51 (B marker) was found in the dwellers of Dagestan: in 70% of the men and 40% of the women who had BD/CONCLUSION: BD runs a more severe course in male patients and is characterized by severe eye diseases and the systematic pattern of the process at young age. Gender-specific and genetic aspects call for further comparative investigations on large ethnic patient cohorts of other ancestries. behçet's disease ethnicity demographic indicators clinical polymorphism hla-b51 Medicine R F I Izmailova verfasserin aut M T Kudaev verfasserin aut In Терапевтический архив "Consilium Medicum" Publishing house, 2018 85(2013), 5, Seite 48-52 (DE-627)1760620270 23095342 nnns volume:85 year:2013 number:5 pages:48-52 https://doaj.org/article/493c22916cf342378159d3bd6f27213a kostenfrei https://ter-arkhiv.ru/0040-3660/article/view/31277 kostenfrei https://doaj.org/toc/0040-3660 Journal toc kostenfrei https://doaj.org/toc/2309-5342 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA AR 85 2013 5 48-52 |
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Behçet's disease: Clinical and demographic associations |
| abstract |
AIM: To comparatively study the clinical manifestations, sexual and HLA-B51 associations in patients with Behçet's disease (BD) in two ethnic groups/MATERIAL AND METHODS: The authors examined 143 patients with the valid diagnosis of BD who were divided into 2 groups: 1) 85 patients, the dwellers of Dagestan (a multiethnic cohort), 63 men and 22 women (mean age 29±7.4 years); 2) 58 Russian men and women (mean age 33±11.7 years)/RESULTS: Two major criteria for BD, such as aphthous stomatitis and external genital ulcers, were found with the same frequency. Panuveitis and angiitis of the retina were diagnosed more frequently in the Dagestani population with BD than in the Russians. Out of the minor criteria for BD, the incidence of lower limb deep venous thrombosis was 23% for the Dagestanis versus 3% for the Russians. Arterial thromboses and pulmonary artery aneurysms became causes of death in 4 in 5 men aged 19-23 years from their Dagestani ancestry. HLA B51 (B marker) was found in the dwellers of Dagestan: in 70% of the men and 40% of the women who had BD/CONCLUSION: BD runs a more severe course in male patients and is characterized by severe eye diseases and the systematic pattern of the process at young age. Gender-specific and genetic aspects call for further comparative investigations on large ethnic patient cohorts of other ancestries. |
| abstractGer |
AIM: To comparatively study the clinical manifestations, sexual and HLA-B51 associations in patients with Behçet's disease (BD) in two ethnic groups/MATERIAL AND METHODS: The authors examined 143 patients with the valid diagnosis of BD who were divided into 2 groups: 1) 85 patients, the dwellers of Dagestan (a multiethnic cohort), 63 men and 22 women (mean age 29±7.4 years); 2) 58 Russian men and women (mean age 33±11.7 years)/RESULTS: Two major criteria for BD, such as aphthous stomatitis and external genital ulcers, were found with the same frequency. Panuveitis and angiitis of the retina were diagnosed more frequently in the Dagestani population with BD than in the Russians. Out of the minor criteria for BD, the incidence of lower limb deep venous thrombosis was 23% for the Dagestanis versus 3% for the Russians. Arterial thromboses and pulmonary artery aneurysms became causes of death in 4 in 5 men aged 19-23 years from their Dagestani ancestry. HLA B51 (B marker) was found in the dwellers of Dagestan: in 70% of the men and 40% of the women who had BD/CONCLUSION: BD runs a more severe course in male patients and is characterized by severe eye diseases and the systematic pattern of the process at young age. Gender-specific and genetic aspects call for further comparative investigations on large ethnic patient cohorts of other ancestries. |
| abstract_unstemmed |
AIM: To comparatively study the clinical manifestations, sexual and HLA-B51 associations in patients with Behçet's disease (BD) in two ethnic groups/MATERIAL AND METHODS: The authors examined 143 patients with the valid diagnosis of BD who were divided into 2 groups: 1) 85 patients, the dwellers of Dagestan (a multiethnic cohort), 63 men and 22 women (mean age 29±7.4 years); 2) 58 Russian men and women (mean age 33±11.7 years)/RESULTS: Two major criteria for BD, such as aphthous stomatitis and external genital ulcers, were found with the same frequency. Panuveitis and angiitis of the retina were diagnosed more frequently in the Dagestani population with BD than in the Russians. Out of the minor criteria for BD, the incidence of lower limb deep venous thrombosis was 23% for the Dagestanis versus 3% for the Russians. Arterial thromboses and pulmonary artery aneurysms became causes of death in 4 in 5 men aged 19-23 years from their Dagestani ancestry. HLA B51 (B marker) was found in the dwellers of Dagestan: in 70% of the men and 40% of the women who had BD/CONCLUSION: BD runs a more severe course in male patients and is characterized by severe eye diseases and the systematic pattern of the process at young age. Gender-specific and genetic aspects call for further comparative investigations on large ethnic patient cohorts of other ancestries. |
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Behçet's disease: Clinical and demographic associations |
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https://doaj.org/article/493c22916cf342378159d3bd6f27213a https://ter-arkhiv.ru/0040-3660/article/view/31277 https://doaj.org/toc/0040-3660 https://doaj.org/toc/2309-5342 |
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F I Izmailova M T Kudaev |
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2024-07-03T14:08:36.993Z |
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