Impact of COVID-19 Pandemic on Sleep Quality, Stress Level and Health-Related Quality of Life—A Large Prospective Cohort Study on Adult Danes

The everyday lives of Danish inhabitants have been affected by the COVID-19 pandemic, e.g., by social distancing, which was employed by the government in March 2020 to prevent the spread of SARS-CoV-2. Moreover, the pandemic has entailed economic consequences for many people. This study aims to asse...
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Autor*in:	Maria Didriksen [verfasserIn] Thomas Werge [verfasserIn] Janna Nissen [verfasserIn] Michael Schwinn [verfasserIn] Erik Sørensen [verfasserIn] Kaspar R. Nielsen [verfasserIn] Mie T. Bruun [verfasserIn] Karina Banasik [verfasserIn] Thomas F. Hansen [verfasserIn] Christian Erikstrup [verfasserIn] Sisse R. Ostrowski [verfasserIn] Poul J. Jennum [verfasserIn] Henrik Hjalgrim [verfasserIn] Henrik Ullum [verfasserIn] Ole B. Pedersen [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	COVID-19 pandemic epidemiology public health mental health sleep

Übergeordnetes Werk:	In: International Journal of Environmental Research and Public Health - MDPI AG, 2005, 18(2021), 7610, p 7610
Übergeordnetes Werk:	volume:18 ; year:2021 ; number:7610, p 7610

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.3390/ijerph18147610

Katalog-ID:	DOAJ008138982

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allfields	10.3390/ijerph18147610 doi (DE-627)DOAJ008138982 (DE-599)DOAJ95408a8000a44094a2e2447094cfd350 DE-627 ger DE-627 rakwb eng Maria Didriksen verfasserin aut Impact of COVID-19 Pandemic on Sleep Quality, Stress Level and Health-Related Quality of Life—A Large Prospective Cohort Study on Adult Danes 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The everyday lives of Danish inhabitants have been affected by the COVID-19 pandemic, e.g., by social distancing, which was employed by the government in March 2020 to prevent the spread of SARS-CoV-2. Moreover, the pandemic has entailed economic consequences for many people. This study aims to assess changes in physical and mental health-related quality of life (MCS, PCS), in stress levels, and quality of sleep during the COVID-19 pandemic and to identify factors that impact such changes, using a prospective national cohort study including 26,453 participants from the Danish Blood Donor Study who answered a health questionnaire before the pandemic and during the pandemic. Descriptive statistics, multivariable linear and multinomial logistic regression analyses were applied. A worsening of MCS and quality of sleep was found, and an overall decrease in stress levels was observed. PCS was decreased in men and slightly increased in women. The extent of health changes was mainly affected by changes in job situation, type of job, previous use of anti-depressive medication and the participants’ level of personal stamina. Thus, living under the unusual circumstances that persisted during the COVID-19 pandemic has had a negative impact on the health of the general population. This may, in time, constitute a public health problem. COVID-19 pandemic epidemiology public health mental health sleep Medicine R Thomas Werge verfasserin aut Janna Nissen verfasserin aut Michael Schwinn verfasserin aut Erik Sørensen verfasserin aut Kaspar R. Nielsen verfasserin aut Mie T. Bruun verfasserin aut Karina Banasik verfasserin aut Thomas F. Hansen verfasserin aut Christian Erikstrup verfasserin aut Sisse R. Ostrowski verfasserin aut Poul J. Jennum verfasserin aut Henrik Hjalgrim verfasserin aut Henrik Ullum verfasserin aut Ole B. Pedersen verfasserin aut In International Journal of Environmental Research and Public Health MDPI AG, 2005 18(2021), 7610, p 7610 (DE-627)477992463 (DE-600)2175195-X 16604601 nnns volume:18 year:2021 number:7610, p 7610 https://doi.org/10.3390/ijerph18147610 kostenfrei https://doaj.org/article/95408a8000a44094a2e2447094cfd350 kostenfrei https://www.mdpi.com/1660-4601/18/14/7610 kostenfrei https://doaj.org/toc/1661-7827 Journal toc kostenfrei https://doaj.org/toc/1660-4601 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2153 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 18 2021 7610, p 7610
spelling	10.3390/ijerph18147610 doi (DE-627)DOAJ008138982 (DE-599)DOAJ95408a8000a44094a2e2447094cfd350 DE-627 ger DE-627 rakwb eng Maria Didriksen verfasserin aut Impact of COVID-19 Pandemic on Sleep Quality, Stress Level and Health-Related Quality of Life—A Large Prospective Cohort Study on Adult Danes 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The everyday lives of Danish inhabitants have been affected by the COVID-19 pandemic, e.g., by social distancing, which was employed by the government in March 2020 to prevent the spread of SARS-CoV-2. Moreover, the pandemic has entailed economic consequences for many people. This study aims to assess changes in physical and mental health-related quality of life (MCS, PCS), in stress levels, and quality of sleep during the COVID-19 pandemic and to identify factors that impact such changes, using a prospective national cohort study including 26,453 participants from the Danish Blood Donor Study who answered a health questionnaire before the pandemic and during the pandemic. Descriptive statistics, multivariable linear and multinomial logistic regression analyses were applied. A worsening of MCS and quality of sleep was found, and an overall decrease in stress levels was observed. PCS was decreased in men and slightly increased in women. The extent of health changes was mainly affected by changes in job situation, type of job, previous use of anti-depressive medication and the participants’ level of personal stamina. Thus, living under the unusual circumstances that persisted during the COVID-19 pandemic has had a negative impact on the health of the general population. This may, in time, constitute a public health problem. COVID-19 pandemic epidemiology public health mental health sleep Medicine R Thomas Werge verfasserin aut Janna Nissen verfasserin aut Michael Schwinn verfasserin aut Erik Sørensen verfasserin aut Kaspar R. Nielsen verfasserin aut Mie T. Bruun verfasserin aut Karina Banasik verfasserin aut Thomas F. Hansen verfasserin aut Christian Erikstrup verfasserin aut Sisse R. Ostrowski verfasserin aut Poul J. Jennum verfasserin aut Henrik Hjalgrim verfasserin aut Henrik Ullum verfasserin aut Ole B. Pedersen verfasserin aut In International Journal of Environmental Research and Public Health MDPI AG, 2005 18(2021), 7610, p 7610 (DE-627)477992463 (DE-600)2175195-X 16604601 nnns volume:18 year:2021 number:7610, p 7610 https://doi.org/10.3390/ijerph18147610 kostenfrei https://doaj.org/article/95408a8000a44094a2e2447094cfd350 kostenfrei https://www.mdpi.com/1660-4601/18/14/7610 kostenfrei https://doaj.org/toc/1661-7827 Journal toc kostenfrei https://doaj.org/toc/1660-4601 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2153 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 18 2021 7610, p 7610
allfields_unstemmed	10.3390/ijerph18147610 doi (DE-627)DOAJ008138982 (DE-599)DOAJ95408a8000a44094a2e2447094cfd350 DE-627 ger DE-627 rakwb eng Maria Didriksen verfasserin aut Impact of COVID-19 Pandemic on Sleep Quality, Stress Level and Health-Related Quality of Life—A Large Prospective Cohort Study on Adult Danes 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The everyday lives of Danish inhabitants have been affected by the COVID-19 pandemic, e.g., by social distancing, which was employed by the government in March 2020 to prevent the spread of SARS-CoV-2. Moreover, the pandemic has entailed economic consequences for many people. This study aims to assess changes in physical and mental health-related quality of life (MCS, PCS), in stress levels, and quality of sleep during the COVID-19 pandemic and to identify factors that impact such changes, using a prospective national cohort study including 26,453 participants from the Danish Blood Donor Study who answered a health questionnaire before the pandemic and during the pandemic. Descriptive statistics, multivariable linear and multinomial logistic regression analyses were applied. A worsening of MCS and quality of sleep was found, and an overall decrease in stress levels was observed. PCS was decreased in men and slightly increased in women. The extent of health changes was mainly affected by changes in job situation, type of job, previous use of anti-depressive medication and the participants’ level of personal stamina. Thus, living under the unusual circumstances that persisted during the COVID-19 pandemic has had a negative impact on the health of the general population. This may, in time, constitute a public health problem. COVID-19 pandemic epidemiology public health mental health sleep Medicine R Thomas Werge verfasserin aut Janna Nissen verfasserin aut Michael Schwinn verfasserin aut Erik Sørensen verfasserin aut Kaspar R. Nielsen verfasserin aut Mie T. Bruun verfasserin aut Karina Banasik verfasserin aut Thomas F. Hansen verfasserin aut Christian Erikstrup verfasserin aut Sisse R. Ostrowski verfasserin aut Poul J. Jennum verfasserin aut Henrik Hjalgrim verfasserin aut Henrik Ullum verfasserin aut Ole B. Pedersen verfasserin aut In International Journal of Environmental Research and Public Health MDPI AG, 2005 18(2021), 7610, p 7610 (DE-627)477992463 (DE-600)2175195-X 16604601 nnns volume:18 year:2021 number:7610, p 7610 https://doi.org/10.3390/ijerph18147610 kostenfrei https://doaj.org/article/95408a8000a44094a2e2447094cfd350 kostenfrei https://www.mdpi.com/1660-4601/18/14/7610 kostenfrei https://doaj.org/toc/1661-7827 Journal toc kostenfrei https://doaj.org/toc/1660-4601 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2153 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 18 2021 7610, p 7610
allfieldsGer	10.3390/ijerph18147610 doi (DE-627)DOAJ008138982 (DE-599)DOAJ95408a8000a44094a2e2447094cfd350 DE-627 ger DE-627 rakwb eng Maria Didriksen verfasserin aut Impact of COVID-19 Pandemic on Sleep Quality, Stress Level and Health-Related Quality of Life—A Large Prospective Cohort Study on Adult Danes 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The everyday lives of Danish inhabitants have been affected by the COVID-19 pandemic, e.g., by social distancing, which was employed by the government in March 2020 to prevent the spread of SARS-CoV-2. Moreover, the pandemic has entailed economic consequences for many people. This study aims to assess changes in physical and mental health-related quality of life (MCS, PCS), in stress levels, and quality of sleep during the COVID-19 pandemic and to identify factors that impact such changes, using a prospective national cohort study including 26,453 participants from the Danish Blood Donor Study who answered a health questionnaire before the pandemic and during the pandemic. Descriptive statistics, multivariable linear and multinomial logistic regression analyses were applied. A worsening of MCS and quality of sleep was found, and an overall decrease in stress levels was observed. PCS was decreased in men and slightly increased in women. The extent of health changes was mainly affected by changes in job situation, type of job, previous use of anti-depressive medication and the participants’ level of personal stamina. Thus, living under the unusual circumstances that persisted during the COVID-19 pandemic has had a negative impact on the health of the general population. This may, in time, constitute a public health problem. COVID-19 pandemic epidemiology public health mental health sleep Medicine R Thomas Werge verfasserin aut Janna Nissen verfasserin aut Michael Schwinn verfasserin aut Erik Sørensen verfasserin aut Kaspar R. Nielsen verfasserin aut Mie T. Bruun verfasserin aut Karina Banasik verfasserin aut Thomas F. Hansen verfasserin aut Christian Erikstrup verfasserin aut Sisse R. Ostrowski verfasserin aut Poul J. Jennum verfasserin aut Henrik Hjalgrim verfasserin aut Henrik Ullum verfasserin aut Ole B. Pedersen verfasserin aut In International Journal of Environmental Research and Public Health MDPI AG, 2005 18(2021), 7610, p 7610 (DE-627)477992463 (DE-600)2175195-X 16604601 nnns volume:18 year:2021 number:7610, p 7610 https://doi.org/10.3390/ijerph18147610 kostenfrei https://doaj.org/article/95408a8000a44094a2e2447094cfd350 kostenfrei https://www.mdpi.com/1660-4601/18/14/7610 kostenfrei https://doaj.org/toc/1661-7827 Journal toc kostenfrei https://doaj.org/toc/1660-4601 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2153 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 18 2021 7610, p 7610
allfieldsSound	10.3390/ijerph18147610 doi (DE-627)DOAJ008138982 (DE-599)DOAJ95408a8000a44094a2e2447094cfd350 DE-627 ger DE-627 rakwb eng Maria Didriksen verfasserin aut Impact of COVID-19 Pandemic on Sleep Quality, Stress Level and Health-Related Quality of Life—A Large Prospective Cohort Study on Adult Danes 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The everyday lives of Danish inhabitants have been affected by the COVID-19 pandemic, e.g., by social distancing, which was employed by the government in March 2020 to prevent the spread of SARS-CoV-2. Moreover, the pandemic has entailed economic consequences for many people. This study aims to assess changes in physical and mental health-related quality of life (MCS, PCS), in stress levels, and quality of sleep during the COVID-19 pandemic and to identify factors that impact such changes, using a prospective national cohort study including 26,453 participants from the Danish Blood Donor Study who answered a health questionnaire before the pandemic and during the pandemic. Descriptive statistics, multivariable linear and multinomial logistic regression analyses were applied. A worsening of MCS and quality of sleep was found, and an overall decrease in stress levels was observed. PCS was decreased in men and slightly increased in women. The extent of health changes was mainly affected by changes in job situation, type of job, previous use of anti-depressive medication and the participants’ level of personal stamina. Thus, living under the unusual circumstances that persisted during the COVID-19 pandemic has had a negative impact on the health of the general population. This may, in time, constitute a public health problem. COVID-19 pandemic epidemiology public health mental health sleep Medicine R Thomas Werge verfasserin aut Janna Nissen verfasserin aut Michael Schwinn verfasserin aut Erik Sørensen verfasserin aut Kaspar R. Nielsen verfasserin aut Mie T. Bruun verfasserin aut Karina Banasik verfasserin aut Thomas F. Hansen verfasserin aut Christian Erikstrup verfasserin aut Sisse R. Ostrowski verfasserin aut Poul J. Jennum verfasserin aut Henrik Hjalgrim verfasserin aut Henrik Ullum verfasserin aut Ole B. Pedersen verfasserin aut In International Journal of Environmental Research and Public Health MDPI AG, 2005 18(2021), 7610, p 7610 (DE-627)477992463 (DE-600)2175195-X 16604601 nnns volume:18 year:2021 number:7610, p 7610 https://doi.org/10.3390/ijerph18147610 kostenfrei https://doaj.org/article/95408a8000a44094a2e2447094cfd350 kostenfrei https://www.mdpi.com/1660-4601/18/14/7610 kostenfrei https://doaj.org/toc/1661-7827 Journal toc kostenfrei https://doaj.org/toc/1660-4601 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2153 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 18 2021 7610, p 7610
language	English
source	In International Journal of Environmental Research and Public Health 18(2021), 7610, p 7610 volume:18 year:2021 number:7610, p 7610
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author	Maria Didriksen
spellingShingle	Maria Didriksen misc COVID-19 misc pandemic misc epidemiology misc public health misc mental health misc sleep misc Medicine misc R Impact of COVID-19 Pandemic on Sleep Quality, Stress Level and Health-Related Quality of Life—A Large Prospective Cohort Study on Adult Danes
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title_auth	Impact of COVID-19 Pandemic on Sleep Quality, Stress Level and Health-Related Quality of Life—A Large Prospective Cohort Study on Adult Danes
abstract	The everyday lives of Danish inhabitants have been affected by the COVID-19 pandemic, e.g., by social distancing, which was employed by the government in March 2020 to prevent the spread of SARS-CoV-2. Moreover, the pandemic has entailed economic consequences for many people. This study aims to assess changes in physical and mental health-related quality of life (MCS, PCS), in stress levels, and quality of sleep during the COVID-19 pandemic and to identify factors that impact such changes, using a prospective national cohort study including 26,453 participants from the Danish Blood Donor Study who answered a health questionnaire before the pandemic and during the pandemic. Descriptive statistics, multivariable linear and multinomial logistic regression analyses were applied. A worsening of MCS and quality of sleep was found, and an overall decrease in stress levels was observed. PCS was decreased in men and slightly increased in women. The extent of health changes was mainly affected by changes in job situation, type of job, previous use of anti-depressive medication and the participants’ level of personal stamina. Thus, living under the unusual circumstances that persisted during the COVID-19 pandemic has had a negative impact on the health of the general population. This may, in time, constitute a public health problem.
abstractGer	The everyday lives of Danish inhabitants have been affected by the COVID-19 pandemic, e.g., by social distancing, which was employed by the government in March 2020 to prevent the spread of SARS-CoV-2. Moreover, the pandemic has entailed economic consequences for many people. This study aims to assess changes in physical and mental health-related quality of life (MCS, PCS), in stress levels, and quality of sleep during the COVID-19 pandemic and to identify factors that impact such changes, using a prospective national cohort study including 26,453 participants from the Danish Blood Donor Study who answered a health questionnaire before the pandemic and during the pandemic. Descriptive statistics, multivariable linear and multinomial logistic regression analyses were applied. A worsening of MCS and quality of sleep was found, and an overall decrease in stress levels was observed. PCS was decreased in men and slightly increased in women. The extent of health changes was mainly affected by changes in job situation, type of job, previous use of anti-depressive medication and the participants’ level of personal stamina. Thus, living under the unusual circumstances that persisted during the COVID-19 pandemic has had a negative impact on the health of the general population. This may, in time, constitute a public health problem.
abstract_unstemmed	The everyday lives of Danish inhabitants have been affected by the COVID-19 pandemic, e.g., by social distancing, which was employed by the government in March 2020 to prevent the spread of SARS-CoV-2. Moreover, the pandemic has entailed economic consequences for many people. This study aims to assess changes in physical and mental health-related quality of life (MCS, PCS), in stress levels, and quality of sleep during the COVID-19 pandemic and to identify factors that impact such changes, using a prospective national cohort study including 26,453 participants from the Danish Blood Donor Study who answered a health questionnaire before the pandemic and during the pandemic. Descriptive statistics, multivariable linear and multinomial logistic regression analyses were applied. A worsening of MCS and quality of sleep was found, and an overall decrease in stress levels was observed. PCS was decreased in men and slightly increased in women. The extent of health changes was mainly affected by changes in job situation, type of job, previous use of anti-depressive medication and the participants’ level of personal stamina. Thus, living under the unusual circumstances that persisted during the COVID-19 pandemic has had a negative impact on the health of the general population. This may, in time, constitute a public health problem.
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Moreover, the pandemic has entailed economic consequences for many people. This study aims to assess changes in physical and mental health-related quality of life (MCS, PCS), in stress levels, and quality of sleep during the COVID-19 pandemic and to identify factors that impact such changes, using a prospective national cohort study including 26,453 participants from the Danish Blood Donor Study who answered a health questionnaire before the pandemic and during the pandemic. Descriptive statistics, multivariable linear and multinomial logistic regression analyses were applied. A worsening of MCS and quality of sleep was found, and an overall decrease in stress levels was observed. PCS was decreased in men and slightly increased in women. The extent of health changes was mainly affected by changes in job situation, type of job, previous use of anti-depressive medication and the participants’ level of personal stamina. Thus, living under the unusual circumstances that persisted during the COVID-19 pandemic has had a negative impact on the health of the general population. 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Impact of COVID-19 Pandemic on Sleep Quality, Stress Level and Health-Related Quality of Life—A Large Prospective Cohort Study on Adult Danes

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