Macrolide-Lincosamide-Streptogramin B Resistance Phenotypes in Methicillin Resistant Staphylococcus aureus Strains Isolated from Patients in Intensive Care Units
Introduction: In this study, we aimed to evaluate the macrolide-lincosamide-streptogramin B resistance phenotypes of methicillin-resistant Staphylococcus aureus strains isolated from patients in intensive care units (ICUs). Materials and Methods: A total of 50 MRSA strains isolated from clinical sam...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Laser Şanal [verfasserIn] Salih Cesur [verfasserIn] Hatice Uludağ Altun [verfasserIn] Neziha Yılmaz [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch ; Türkisch |
| Erschienen: |
2017 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
In: Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi - Bilimsel Tip Yayinevi, 2018, 22(2017), 1, Seite 29-33 |
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| Übergeordnetes Werk: |
volume:22 ; year:2017 ; number:1 ; pages:29-33 |
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Link aufrufen |
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| DOI / URN: |
10.5578/flora.58638 |
|---|
| Katalog-ID: |
DOAJ008267685 |
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| 520 | |a Introduction: In this study, we aimed to evaluate the macrolide-lincosamide-streptogramin B resistance phenotypes of methicillin-resistant Staphylococcus aureus strains isolated from patients in intensive care units (ICUs). Materials and Methods: A total of 50 MRSA strains isolated from clinical samples (45 blood, 5 tracheal aspirate) of patients in ICUs between 2013-2016 were included into the study. MLSB resistant phenotypes were investigated by D test method using erythromycin (15 μg Oxoid, UK) and clindamycin (2 μg Oxoid, UK) disks. Detecting resistance for both erythromycin and clindamycin were defined as constitutive MLSB (cMLSB), a flattening of the inhibition zone around the clindamycin disk proximal to the erythromycin disk (producing a zone of inhibition shaped like the letter D) as inducible MLSB (iMLSB), non-existence of D zone despite erythromycin resistance and clindamycin susceptibility as MSB, erythromycin and clindamycin susceptible strains as S phenotype. Results: Of all the 50 MRSA strains tested, resistance rates for erythromycin and clindamycin were as 84% and 48%, respectively. Among all tested strains, cMLSB, iMLSB and MSB resistance rates were detected as 57.1%, 35.7% and 7.1%, respectively. Eight strains were susceptible for both erythromycin and clindamycin and defined as S phenotype. Conclusion: iMLSB resistance in staphylococci can be detected easily in the microbiology laboratory by D test, which is an inexpensive but reliable method, by using clindamycin and erythromycin disks. Performing D test routinely in erythromycin resistant staphylococci strains and determining iMLSB resistance will prevent the inappropriate usage of clindamycin and will therefore play an important role in the prevention of treatment failures. | ||
| 650 | 4 | |a Macrolide-lincosamide-streptogramin B | |
| 650 | 4 | |a Resistance phenotypes | |
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| 700 | 0 | |a Hatice Uludağ Altun |e verfasserin |4 aut | |
| 700 | 0 | |a Neziha Yılmaz |e verfasserin |4 aut | |
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10.5578/flora.58638 doi (DE-627)DOAJ008267685 (DE-599)DOAJd1910ec955f042a6ba70b790d81bb589 DE-627 ger DE-627 rakwb eng tur RC109-216 QR1-502 Laser Şanal verfasserin aut Macrolide-Lincosamide-Streptogramin B Resistance Phenotypes in Methicillin Resistant Staphylococcus aureus Strains Isolated from Patients in Intensive Care Units 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: In this study, we aimed to evaluate the macrolide-lincosamide-streptogramin B resistance phenotypes of methicillin-resistant Staphylococcus aureus strains isolated from patients in intensive care units (ICUs). Materials and Methods: A total of 50 MRSA strains isolated from clinical samples (45 blood, 5 tracheal aspirate) of patients in ICUs between 2013-2016 were included into the study. MLSB resistant phenotypes were investigated by D test method using erythromycin (15 μg Oxoid, UK) and clindamycin (2 μg Oxoid, UK) disks. Detecting resistance for both erythromycin and clindamycin were defined as constitutive MLSB (cMLSB), a flattening of the inhibition zone around the clindamycin disk proximal to the erythromycin disk (producing a zone of inhibition shaped like the letter D) as inducible MLSB (iMLSB), non-existence of D zone despite erythromycin resistance and clindamycin susceptibility as MSB, erythromycin and clindamycin susceptible strains as S phenotype. Results: Of all the 50 MRSA strains tested, resistance rates for erythromycin and clindamycin were as 84% and 48%, respectively. Among all tested strains, cMLSB, iMLSB and MSB resistance rates were detected as 57.1%, 35.7% and 7.1%, respectively. Eight strains were susceptible for both erythromycin and clindamycin and defined as S phenotype. Conclusion: iMLSB resistance in staphylococci can be detected easily in the microbiology laboratory by D test, which is an inexpensive but reliable method, by using clindamycin and erythromycin disks. Performing D test routinely in erythromycin resistant staphylococci strains and determining iMLSB resistance will prevent the inappropriate usage of clindamycin and will therefore play an important role in the prevention of treatment failures. Macrolide-lincosamide-streptogramin B Resistance phenotypes Staphylococcus aureus Infectious and parasitic diseases Microbiology Salih Cesur verfasserin aut Hatice Uludağ Altun verfasserin aut Neziha Yılmaz verfasserin aut In Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi Bilimsel Tip Yayinevi, 2018 22(2017), 1, Seite 29-33 (DE-627)176059993X 1300932X nnns volume:22 year:2017 number:1 pages:29-33 https://doi.org/10.5578/flora.58638 kostenfrei https://doaj.org/article/d1910ec955f042a6ba70b790d81bb589 kostenfrei http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2017-22-01-029-033.pdf kostenfrei https://doaj.org/toc/1300-932X Journal toc kostenfrei https://doaj.org/toc/1300-932X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 22 2017 1 29-33 |
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10.5578/flora.58638 doi (DE-627)DOAJ008267685 (DE-599)DOAJd1910ec955f042a6ba70b790d81bb589 DE-627 ger DE-627 rakwb eng tur RC109-216 QR1-502 Laser Şanal verfasserin aut Macrolide-Lincosamide-Streptogramin B Resistance Phenotypes in Methicillin Resistant Staphylococcus aureus Strains Isolated from Patients in Intensive Care Units 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: In this study, we aimed to evaluate the macrolide-lincosamide-streptogramin B resistance phenotypes of methicillin-resistant Staphylococcus aureus strains isolated from patients in intensive care units (ICUs). Materials and Methods: A total of 50 MRSA strains isolated from clinical samples (45 blood, 5 tracheal aspirate) of patients in ICUs between 2013-2016 were included into the study. MLSB resistant phenotypes were investigated by D test method using erythromycin (15 μg Oxoid, UK) and clindamycin (2 μg Oxoid, UK) disks. Detecting resistance for both erythromycin and clindamycin were defined as constitutive MLSB (cMLSB), a flattening of the inhibition zone around the clindamycin disk proximal to the erythromycin disk (producing a zone of inhibition shaped like the letter D) as inducible MLSB (iMLSB), non-existence of D zone despite erythromycin resistance and clindamycin susceptibility as MSB, erythromycin and clindamycin susceptible strains as S phenotype. Results: Of all the 50 MRSA strains tested, resistance rates for erythromycin and clindamycin were as 84% and 48%, respectively. Among all tested strains, cMLSB, iMLSB and MSB resistance rates were detected as 57.1%, 35.7% and 7.1%, respectively. Eight strains were susceptible for both erythromycin and clindamycin and defined as S phenotype. Conclusion: iMLSB resistance in staphylococci can be detected easily in the microbiology laboratory by D test, which is an inexpensive but reliable method, by using clindamycin and erythromycin disks. Performing D test routinely in erythromycin resistant staphylococci strains and determining iMLSB resistance will prevent the inappropriate usage of clindamycin and will therefore play an important role in the prevention of treatment failures. Macrolide-lincosamide-streptogramin B Resistance phenotypes Staphylococcus aureus Infectious and parasitic diseases Microbiology Salih Cesur verfasserin aut Hatice Uludağ Altun verfasserin aut Neziha Yılmaz verfasserin aut In Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi Bilimsel Tip Yayinevi, 2018 22(2017), 1, Seite 29-33 (DE-627)176059993X 1300932X nnns volume:22 year:2017 number:1 pages:29-33 https://doi.org/10.5578/flora.58638 kostenfrei https://doaj.org/article/d1910ec955f042a6ba70b790d81bb589 kostenfrei http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2017-22-01-029-033.pdf kostenfrei https://doaj.org/toc/1300-932X Journal toc kostenfrei https://doaj.org/toc/1300-932X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 22 2017 1 29-33 |
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10.5578/flora.58638 doi (DE-627)DOAJ008267685 (DE-599)DOAJd1910ec955f042a6ba70b790d81bb589 DE-627 ger DE-627 rakwb eng tur RC109-216 QR1-502 Laser Şanal verfasserin aut Macrolide-Lincosamide-Streptogramin B Resistance Phenotypes in Methicillin Resistant Staphylococcus aureus Strains Isolated from Patients in Intensive Care Units 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: In this study, we aimed to evaluate the macrolide-lincosamide-streptogramin B resistance phenotypes of methicillin-resistant Staphylococcus aureus strains isolated from patients in intensive care units (ICUs). Materials and Methods: A total of 50 MRSA strains isolated from clinical samples (45 blood, 5 tracheal aspirate) of patients in ICUs between 2013-2016 were included into the study. MLSB resistant phenotypes were investigated by D test method using erythromycin (15 μg Oxoid, UK) and clindamycin (2 μg Oxoid, UK) disks. Detecting resistance for both erythromycin and clindamycin were defined as constitutive MLSB (cMLSB), a flattening of the inhibition zone around the clindamycin disk proximal to the erythromycin disk (producing a zone of inhibition shaped like the letter D) as inducible MLSB (iMLSB), non-existence of D zone despite erythromycin resistance and clindamycin susceptibility as MSB, erythromycin and clindamycin susceptible strains as S phenotype. Results: Of all the 50 MRSA strains tested, resistance rates for erythromycin and clindamycin were as 84% and 48%, respectively. Among all tested strains, cMLSB, iMLSB and MSB resistance rates were detected as 57.1%, 35.7% and 7.1%, respectively. Eight strains were susceptible for both erythromycin and clindamycin and defined as S phenotype. Conclusion: iMLSB resistance in staphylococci can be detected easily in the microbiology laboratory by D test, which is an inexpensive but reliable method, by using clindamycin and erythromycin disks. Performing D test routinely in erythromycin resistant staphylococci strains and determining iMLSB resistance will prevent the inappropriate usage of clindamycin and will therefore play an important role in the prevention of treatment failures. Macrolide-lincosamide-streptogramin B Resistance phenotypes Staphylococcus aureus Infectious and parasitic diseases Microbiology Salih Cesur verfasserin aut Hatice Uludağ Altun verfasserin aut Neziha Yılmaz verfasserin aut In Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi Bilimsel Tip Yayinevi, 2018 22(2017), 1, Seite 29-33 (DE-627)176059993X 1300932X nnns volume:22 year:2017 number:1 pages:29-33 https://doi.org/10.5578/flora.58638 kostenfrei https://doaj.org/article/d1910ec955f042a6ba70b790d81bb589 kostenfrei http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2017-22-01-029-033.pdf kostenfrei https://doaj.org/toc/1300-932X Journal toc kostenfrei https://doaj.org/toc/1300-932X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 22 2017 1 29-33 |
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10.5578/flora.58638 doi (DE-627)DOAJ008267685 (DE-599)DOAJd1910ec955f042a6ba70b790d81bb589 DE-627 ger DE-627 rakwb eng tur RC109-216 QR1-502 Laser Şanal verfasserin aut Macrolide-Lincosamide-Streptogramin B Resistance Phenotypes in Methicillin Resistant Staphylococcus aureus Strains Isolated from Patients in Intensive Care Units 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: In this study, we aimed to evaluate the macrolide-lincosamide-streptogramin B resistance phenotypes of methicillin-resistant Staphylococcus aureus strains isolated from patients in intensive care units (ICUs). Materials and Methods: A total of 50 MRSA strains isolated from clinical samples (45 blood, 5 tracheal aspirate) of patients in ICUs between 2013-2016 were included into the study. MLSB resistant phenotypes were investigated by D test method using erythromycin (15 μg Oxoid, UK) and clindamycin (2 μg Oxoid, UK) disks. Detecting resistance for both erythromycin and clindamycin were defined as constitutive MLSB (cMLSB), a flattening of the inhibition zone around the clindamycin disk proximal to the erythromycin disk (producing a zone of inhibition shaped like the letter D) as inducible MLSB (iMLSB), non-existence of D zone despite erythromycin resistance and clindamycin susceptibility as MSB, erythromycin and clindamycin susceptible strains as S phenotype. Results: Of all the 50 MRSA strains tested, resistance rates for erythromycin and clindamycin were as 84% and 48%, respectively. Among all tested strains, cMLSB, iMLSB and MSB resistance rates were detected as 57.1%, 35.7% and 7.1%, respectively. Eight strains were susceptible for both erythromycin and clindamycin and defined as S phenotype. Conclusion: iMLSB resistance in staphylococci can be detected easily in the microbiology laboratory by D test, which is an inexpensive but reliable method, by using clindamycin and erythromycin disks. Performing D test routinely in erythromycin resistant staphylococci strains and determining iMLSB resistance will prevent the inappropriate usage of clindamycin and will therefore play an important role in the prevention of treatment failures. Macrolide-lincosamide-streptogramin B Resistance phenotypes Staphylococcus aureus Infectious and parasitic diseases Microbiology Salih Cesur verfasserin aut Hatice Uludağ Altun verfasserin aut Neziha Yılmaz verfasserin aut In Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi Bilimsel Tip Yayinevi, 2018 22(2017), 1, Seite 29-33 (DE-627)176059993X 1300932X nnns volume:22 year:2017 number:1 pages:29-33 https://doi.org/10.5578/flora.58638 kostenfrei https://doaj.org/article/d1910ec955f042a6ba70b790d81bb589 kostenfrei http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2017-22-01-029-033.pdf kostenfrei https://doaj.org/toc/1300-932X Journal toc kostenfrei https://doaj.org/toc/1300-932X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 22 2017 1 29-33 |
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10.5578/flora.58638 doi (DE-627)DOAJ008267685 (DE-599)DOAJd1910ec955f042a6ba70b790d81bb589 DE-627 ger DE-627 rakwb eng tur RC109-216 QR1-502 Laser Şanal verfasserin aut Macrolide-Lincosamide-Streptogramin B Resistance Phenotypes in Methicillin Resistant Staphylococcus aureus Strains Isolated from Patients in Intensive Care Units 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: In this study, we aimed to evaluate the macrolide-lincosamide-streptogramin B resistance phenotypes of methicillin-resistant Staphylococcus aureus strains isolated from patients in intensive care units (ICUs). Materials and Methods: A total of 50 MRSA strains isolated from clinical samples (45 blood, 5 tracheal aspirate) of patients in ICUs between 2013-2016 were included into the study. MLSB resistant phenotypes were investigated by D test method using erythromycin (15 μg Oxoid, UK) and clindamycin (2 μg Oxoid, UK) disks. Detecting resistance for both erythromycin and clindamycin were defined as constitutive MLSB (cMLSB), a flattening of the inhibition zone around the clindamycin disk proximal to the erythromycin disk (producing a zone of inhibition shaped like the letter D) as inducible MLSB (iMLSB), non-existence of D zone despite erythromycin resistance and clindamycin susceptibility as MSB, erythromycin and clindamycin susceptible strains as S phenotype. Results: Of all the 50 MRSA strains tested, resistance rates for erythromycin and clindamycin were as 84% and 48%, respectively. Among all tested strains, cMLSB, iMLSB and MSB resistance rates were detected as 57.1%, 35.7% and 7.1%, respectively. Eight strains were susceptible for both erythromycin and clindamycin and defined as S phenotype. Conclusion: iMLSB resistance in staphylococci can be detected easily in the microbiology laboratory by D test, which is an inexpensive but reliable method, by using clindamycin and erythromycin disks. Performing D test routinely in erythromycin resistant staphylococci strains and determining iMLSB resistance will prevent the inappropriate usage of clindamycin and will therefore play an important role in the prevention of treatment failures. Macrolide-lincosamide-streptogramin B Resistance phenotypes Staphylococcus aureus Infectious and parasitic diseases Microbiology Salih Cesur verfasserin aut Hatice Uludağ Altun verfasserin aut Neziha Yılmaz verfasserin aut In Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi Bilimsel Tip Yayinevi, 2018 22(2017), 1, Seite 29-33 (DE-627)176059993X 1300932X nnns volume:22 year:2017 number:1 pages:29-33 https://doi.org/10.5578/flora.58638 kostenfrei https://doaj.org/article/d1910ec955f042a6ba70b790d81bb589 kostenfrei http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2017-22-01-029-033.pdf kostenfrei https://doaj.org/toc/1300-932X Journal toc kostenfrei https://doaj.org/toc/1300-932X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 22 2017 1 29-33 |
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In Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi 22(2017), 1, Seite 29-33 volume:22 year:2017 number:1 pages:29-33 |
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Materials and Methods: A total of 50 MRSA strains isolated from clinical samples (45 blood, 5 tracheal aspirate) of patients in ICUs between 2013-2016 were included into the study. MLSB resistant phenotypes were investigated by D test method using erythromycin (15 μg Oxoid, UK) and clindamycin (2 μg Oxoid, UK) disks. Detecting resistance for both erythromycin and clindamycin were defined as constitutive MLSB (cMLSB), a flattening of the inhibition zone around the clindamycin disk proximal to the erythromycin disk (producing a zone of inhibition shaped like the letter D) as inducible MLSB (iMLSB), non-existence of D zone despite erythromycin resistance and clindamycin susceptibility as MSB, erythromycin and clindamycin susceptible strains as S phenotype. Results: Of all the 50 MRSA strains tested, resistance rates for erythromycin and clindamycin were as 84% and 48%, respectively. Among all tested strains, cMLSB, iMLSB and MSB resistance rates were detected as 57.1%, 35.7% and 7.1%, respectively. Eight strains were susceptible for both erythromycin and clindamycin and defined as S phenotype. Conclusion: iMLSB resistance in staphylococci can be detected easily in the microbiology laboratory by D test, which is an inexpensive but reliable method, by using clindamycin and erythromycin disks. 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macrolide-lincosamide-streptogramin b resistance phenotypes in methicillin resistant staphylococcus aureus strains isolated from patients in intensive care units |
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Macrolide-Lincosamide-Streptogramin B Resistance Phenotypes in Methicillin Resistant Staphylococcus aureus Strains Isolated from Patients in Intensive Care Units |
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Introduction: In this study, we aimed to evaluate the macrolide-lincosamide-streptogramin B resistance phenotypes of methicillin-resistant Staphylococcus aureus strains isolated from patients in intensive care units (ICUs). Materials and Methods: A total of 50 MRSA strains isolated from clinical samples (45 blood, 5 tracheal aspirate) of patients in ICUs between 2013-2016 were included into the study. MLSB resistant phenotypes were investigated by D test method using erythromycin (15 μg Oxoid, UK) and clindamycin (2 μg Oxoid, UK) disks. Detecting resistance for both erythromycin and clindamycin were defined as constitutive MLSB (cMLSB), a flattening of the inhibition zone around the clindamycin disk proximal to the erythromycin disk (producing a zone of inhibition shaped like the letter D) as inducible MLSB (iMLSB), non-existence of D zone despite erythromycin resistance and clindamycin susceptibility as MSB, erythromycin and clindamycin susceptible strains as S phenotype. Results: Of all the 50 MRSA strains tested, resistance rates for erythromycin and clindamycin were as 84% and 48%, respectively. Among all tested strains, cMLSB, iMLSB and MSB resistance rates were detected as 57.1%, 35.7% and 7.1%, respectively. Eight strains were susceptible for both erythromycin and clindamycin and defined as S phenotype. Conclusion: iMLSB resistance in staphylococci can be detected easily in the microbiology laboratory by D test, which is an inexpensive but reliable method, by using clindamycin and erythromycin disks. Performing D test routinely in erythromycin resistant staphylococci strains and determining iMLSB resistance will prevent the inappropriate usage of clindamycin and will therefore play an important role in the prevention of treatment failures. |
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Introduction: In this study, we aimed to evaluate the macrolide-lincosamide-streptogramin B resistance phenotypes of methicillin-resistant Staphylococcus aureus strains isolated from patients in intensive care units (ICUs). Materials and Methods: A total of 50 MRSA strains isolated from clinical samples (45 blood, 5 tracheal aspirate) of patients in ICUs between 2013-2016 were included into the study. MLSB resistant phenotypes were investigated by D test method using erythromycin (15 μg Oxoid, UK) and clindamycin (2 μg Oxoid, UK) disks. Detecting resistance for both erythromycin and clindamycin were defined as constitutive MLSB (cMLSB), a flattening of the inhibition zone around the clindamycin disk proximal to the erythromycin disk (producing a zone of inhibition shaped like the letter D) as inducible MLSB (iMLSB), non-existence of D zone despite erythromycin resistance and clindamycin susceptibility as MSB, erythromycin and clindamycin susceptible strains as S phenotype. Results: Of all the 50 MRSA strains tested, resistance rates for erythromycin and clindamycin were as 84% and 48%, respectively. Among all tested strains, cMLSB, iMLSB and MSB resistance rates were detected as 57.1%, 35.7% and 7.1%, respectively. Eight strains were susceptible for both erythromycin and clindamycin and defined as S phenotype. Conclusion: iMLSB resistance in staphylococci can be detected easily in the microbiology laboratory by D test, which is an inexpensive but reliable method, by using clindamycin and erythromycin disks. Performing D test routinely in erythromycin resistant staphylococci strains and determining iMLSB resistance will prevent the inappropriate usage of clindamycin and will therefore play an important role in the prevention of treatment failures. |
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Introduction: In this study, we aimed to evaluate the macrolide-lincosamide-streptogramin B resistance phenotypes of methicillin-resistant Staphylococcus aureus strains isolated from patients in intensive care units (ICUs). Materials and Methods: A total of 50 MRSA strains isolated from clinical samples (45 blood, 5 tracheal aspirate) of patients in ICUs between 2013-2016 were included into the study. MLSB resistant phenotypes were investigated by D test method using erythromycin (15 μg Oxoid, UK) and clindamycin (2 μg Oxoid, UK) disks. Detecting resistance for both erythromycin and clindamycin were defined as constitutive MLSB (cMLSB), a flattening of the inhibition zone around the clindamycin disk proximal to the erythromycin disk (producing a zone of inhibition shaped like the letter D) as inducible MLSB (iMLSB), non-existence of D zone despite erythromycin resistance and clindamycin susceptibility as MSB, erythromycin and clindamycin susceptible strains as S phenotype. Results: Of all the 50 MRSA strains tested, resistance rates for erythromycin and clindamycin were as 84% and 48%, respectively. Among all tested strains, cMLSB, iMLSB and MSB resistance rates were detected as 57.1%, 35.7% and 7.1%, respectively. Eight strains were susceptible for both erythromycin and clindamycin and defined as S phenotype. Conclusion: iMLSB resistance in staphylococci can be detected easily in the microbiology laboratory by D test, which is an inexpensive but reliable method, by using clindamycin and erythromycin disks. Performing D test routinely in erythromycin resistant staphylococci strains and determining iMLSB resistance will prevent the inappropriate usage of clindamycin and will therefore play an important role in the prevention of treatment failures. |
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