Duration of Implantable Cardiac Monitoring and Detection of Atrial Fibrillation in Ischemic Stroke Patients: A Systematic Review and Meta-Analysis
Background and Purpose Current guidelines do not provide firm directions on atrial fibrillation (AF) screening after ischemic stroke (IS). We sought to investigate the association of implantable cardiac monitoring (ICM) duration with the yield of AF detection in IS patients. Methods We included stud...
Ausführliche Beschreibung
Autor*in: |
Georgios Tsivgoulis [verfasserIn] Aristeidis H. Katsanos [verfasserIn] Martin Köhrmann [verfasserIn] Valeria Caso [verfasserIn] Fabienne Perren [verfasserIn] Lina Palaiodimou [verfasserIn] Spyridon Deftereos [verfasserIn] Sotirios Giannopoulos [verfasserIn] John Ellul [verfasserIn] Christos Krogias [verfasserIn] Dimitris Mavridis [verfasserIn] Sokratis Triantafyllou [verfasserIn] Anne W. Alexandrov [verfasserIn] Peter D. Schellinger [verfasserIn] Andrei V. Alexandrov [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
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2019 |
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In: Journal of Stroke - Korean Stroke Society, 2020, 21(2019), 3, Seite 302-311 |
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Übergeordnetes Werk: |
volume:21 ; year:2019 ; number:3 ; pages:302-311 |
Links: |
Link aufrufen |
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DOI / URN: |
10.5853/jos.2019.01067 |
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Katalog-ID: |
DOAJ008452512 |
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520 | |a Background and Purpose Current guidelines do not provide firm directions on atrial fibrillation (AF) screening after ischemic stroke (IS). We sought to investigate the association of implantable cardiac monitoring (ICM) duration with the yield of AF detection in IS patients. Methods We included studies reporting AF detection rates by ICM in IS patients with negative initial AF screening. We excluded studies reporting prolonged cardiac monitoring with devices other than ICM, not providing AF detection rates or monitoring duration, and reporting overlapping data for the same population. The random-effects model was used for all pooled estimates and meta-regression analyses. Results We included 28 studies (4,531 patients, mean age 65 years). In meta-regression analyses, the proportion of AF detection by ICM was independently associated with monitoring duration (coefficient=0.015; 95% confidence interval [CI], 0.005 to 0.024) and mean patient age (coefficient=0.009; 95% CI, 0.003 to 0.015). No associations were detected with other patient characteristics, including IS subtype (cryptogenic vs. embolic stroke of undetermined source) or time from IS onset to CM implantation. In subgroup analyses, significant differences (P<0.001) in the AF detection rates were found for ICM duration (<6 months: 5% [95% CI, 3% to 6%]; ≥6 and ≤12 months: 21% [95% CI, 16% to 25%]; <12 and ≤24 months: 26% [95% CI, 22% to 31%]; <24 months: 34% [95% CI, 29% to 39%]). Conclusions Extended duration of ICM monitoring and increased patient age are factors that substantially increase AF detection in IS patients with initial negative AF screening. | ||
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10.5853/jos.2019.01067 doi (DE-627)DOAJ008452512 (DE-599)DOAJ705a7b54db6a4a8ea08d97b2a3e9cff1 DE-627 ger DE-627 rakwb eng RC666-701 Georgios Tsivgoulis verfasserin aut Duration of Implantable Cardiac Monitoring and Detection of Atrial Fibrillation in Ischemic Stroke Patients: A Systematic Review and Meta-Analysis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background and Purpose Current guidelines do not provide firm directions on atrial fibrillation (AF) screening after ischemic stroke (IS). We sought to investigate the association of implantable cardiac monitoring (ICM) duration with the yield of AF detection in IS patients. Methods We included studies reporting AF detection rates by ICM in IS patients with negative initial AF screening. We excluded studies reporting prolonged cardiac monitoring with devices other than ICM, not providing AF detection rates or monitoring duration, and reporting overlapping data for the same population. The random-effects model was used for all pooled estimates and meta-regression analyses. Results We included 28 studies (4,531 patients, mean age 65 years). In meta-regression analyses, the proportion of AF detection by ICM was independently associated with monitoring duration (coefficient=0.015; 95% confidence interval [CI], 0.005 to 0.024) and mean patient age (coefficient=0.009; 95% CI, 0.003 to 0.015). No associations were detected with other patient characteristics, including IS subtype (cryptogenic vs. embolic stroke of undetermined source) or time from IS onset to CM implantation. In subgroup analyses, significant differences (P<0.001) in the AF detection rates were found for ICM duration (<6 months: 5% [95% CI, 3% to 6%]; ≥6 and ≤12 months: 21% [95% CI, 16% to 25%]; <12 and ≤24 months: 26% [95% CI, 22% to 31%]; <24 months: 34% [95% CI, 29% to 39%]). Conclusions Extended duration of ICM monitoring and increased patient age are factors that substantially increase AF detection in IS patients with initial negative AF screening. atrial fibrillation stroke monitoring meta-analysis Diseases of the circulatory (Cardiovascular) system Aristeidis H. Katsanos verfasserin aut Martin Köhrmann verfasserin aut Valeria Caso verfasserin aut Fabienne Perren verfasserin aut Lina Palaiodimou verfasserin aut Spyridon Deftereos verfasserin aut Sotirios Giannopoulos verfasserin aut John Ellul verfasserin aut Christos Krogias verfasserin aut Dimitris Mavridis verfasserin aut Sokratis Triantafyllou verfasserin aut Anne W. Alexandrov verfasserin aut Peter D. Schellinger verfasserin aut Andrei V. Alexandrov verfasserin aut In Journal of Stroke Korean Stroke Society, 2020 21(2019), 3, Seite 302-311 (DE-627)820686573 (DE-600)2814366-8 22876405 nnns volume:21 year:2019 number:3 pages:302-311 https://doi.org/10.5853/jos.2019.01067 kostenfrei https://doaj.org/article/705a7b54db6a4a8ea08d97b2a3e9cff1 kostenfrei http://www.j-stroke.org/upload/pdf/jos-2019-01067.pdf kostenfrei https://doaj.org/toc/2287-6391 Journal toc kostenfrei https://doaj.org/toc/2287-6405 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21 2019 3 302-311 |
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10.5853/jos.2019.01067 doi (DE-627)DOAJ008452512 (DE-599)DOAJ705a7b54db6a4a8ea08d97b2a3e9cff1 DE-627 ger DE-627 rakwb eng RC666-701 Georgios Tsivgoulis verfasserin aut Duration of Implantable Cardiac Monitoring and Detection of Atrial Fibrillation in Ischemic Stroke Patients: A Systematic Review and Meta-Analysis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background and Purpose Current guidelines do not provide firm directions on atrial fibrillation (AF) screening after ischemic stroke (IS). We sought to investigate the association of implantable cardiac monitoring (ICM) duration with the yield of AF detection in IS patients. Methods We included studies reporting AF detection rates by ICM in IS patients with negative initial AF screening. We excluded studies reporting prolonged cardiac monitoring with devices other than ICM, not providing AF detection rates or monitoring duration, and reporting overlapping data for the same population. The random-effects model was used for all pooled estimates and meta-regression analyses. Results We included 28 studies (4,531 patients, mean age 65 years). In meta-regression analyses, the proportion of AF detection by ICM was independently associated with monitoring duration (coefficient=0.015; 95% confidence interval [CI], 0.005 to 0.024) and mean patient age (coefficient=0.009; 95% CI, 0.003 to 0.015). No associations were detected with other patient characteristics, including IS subtype (cryptogenic vs. embolic stroke of undetermined source) or time from IS onset to CM implantation. In subgroup analyses, significant differences (P<0.001) in the AF detection rates were found for ICM duration (<6 months: 5% [95% CI, 3% to 6%]; ≥6 and ≤12 months: 21% [95% CI, 16% to 25%]; <12 and ≤24 months: 26% [95% CI, 22% to 31%]; <24 months: 34% [95% CI, 29% to 39%]). Conclusions Extended duration of ICM monitoring and increased patient age are factors that substantially increase AF detection in IS patients with initial negative AF screening. atrial fibrillation stroke monitoring meta-analysis Diseases of the circulatory (Cardiovascular) system Aristeidis H. Katsanos verfasserin aut Martin Köhrmann verfasserin aut Valeria Caso verfasserin aut Fabienne Perren verfasserin aut Lina Palaiodimou verfasserin aut Spyridon Deftereos verfasserin aut Sotirios Giannopoulos verfasserin aut John Ellul verfasserin aut Christos Krogias verfasserin aut Dimitris Mavridis verfasserin aut Sokratis Triantafyllou verfasserin aut Anne W. Alexandrov verfasserin aut Peter D. Schellinger verfasserin aut Andrei V. Alexandrov verfasserin aut In Journal of Stroke Korean Stroke Society, 2020 21(2019), 3, Seite 302-311 (DE-627)820686573 (DE-600)2814366-8 22876405 nnns volume:21 year:2019 number:3 pages:302-311 https://doi.org/10.5853/jos.2019.01067 kostenfrei https://doaj.org/article/705a7b54db6a4a8ea08d97b2a3e9cff1 kostenfrei http://www.j-stroke.org/upload/pdf/jos-2019-01067.pdf kostenfrei https://doaj.org/toc/2287-6391 Journal toc kostenfrei https://doaj.org/toc/2287-6405 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21 2019 3 302-311 |
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10.5853/jos.2019.01067 doi (DE-627)DOAJ008452512 (DE-599)DOAJ705a7b54db6a4a8ea08d97b2a3e9cff1 DE-627 ger DE-627 rakwb eng RC666-701 Georgios Tsivgoulis verfasserin aut Duration of Implantable Cardiac Monitoring and Detection of Atrial Fibrillation in Ischemic Stroke Patients: A Systematic Review and Meta-Analysis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background and Purpose Current guidelines do not provide firm directions on atrial fibrillation (AF) screening after ischemic stroke (IS). We sought to investigate the association of implantable cardiac monitoring (ICM) duration with the yield of AF detection in IS patients. Methods We included studies reporting AF detection rates by ICM in IS patients with negative initial AF screening. We excluded studies reporting prolonged cardiac monitoring with devices other than ICM, not providing AF detection rates or monitoring duration, and reporting overlapping data for the same population. The random-effects model was used for all pooled estimates and meta-regression analyses. Results We included 28 studies (4,531 patients, mean age 65 years). In meta-regression analyses, the proportion of AF detection by ICM was independently associated with monitoring duration (coefficient=0.015; 95% confidence interval [CI], 0.005 to 0.024) and mean patient age (coefficient=0.009; 95% CI, 0.003 to 0.015). No associations were detected with other patient characteristics, including IS subtype (cryptogenic vs. embolic stroke of undetermined source) or time from IS onset to CM implantation. In subgroup analyses, significant differences (P<0.001) in the AF detection rates were found for ICM duration (<6 months: 5% [95% CI, 3% to 6%]; ≥6 and ≤12 months: 21% [95% CI, 16% to 25%]; <12 and ≤24 months: 26% [95% CI, 22% to 31%]; <24 months: 34% [95% CI, 29% to 39%]). Conclusions Extended duration of ICM monitoring and increased patient age are factors that substantially increase AF detection in IS patients with initial negative AF screening. atrial fibrillation stroke monitoring meta-analysis Diseases of the circulatory (Cardiovascular) system Aristeidis H. Katsanos verfasserin aut Martin Köhrmann verfasserin aut Valeria Caso verfasserin aut Fabienne Perren verfasserin aut Lina Palaiodimou verfasserin aut Spyridon Deftereos verfasserin aut Sotirios Giannopoulos verfasserin aut John Ellul verfasserin aut Christos Krogias verfasserin aut Dimitris Mavridis verfasserin aut Sokratis Triantafyllou verfasserin aut Anne W. Alexandrov verfasserin aut Peter D. Schellinger verfasserin aut Andrei V. Alexandrov verfasserin aut In Journal of Stroke Korean Stroke Society, 2020 21(2019), 3, Seite 302-311 (DE-627)820686573 (DE-600)2814366-8 22876405 nnns volume:21 year:2019 number:3 pages:302-311 https://doi.org/10.5853/jos.2019.01067 kostenfrei https://doaj.org/article/705a7b54db6a4a8ea08d97b2a3e9cff1 kostenfrei http://www.j-stroke.org/upload/pdf/jos-2019-01067.pdf kostenfrei https://doaj.org/toc/2287-6391 Journal toc kostenfrei https://doaj.org/toc/2287-6405 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21 2019 3 302-311 |
allfieldsGer |
10.5853/jos.2019.01067 doi (DE-627)DOAJ008452512 (DE-599)DOAJ705a7b54db6a4a8ea08d97b2a3e9cff1 DE-627 ger DE-627 rakwb eng RC666-701 Georgios Tsivgoulis verfasserin aut Duration of Implantable Cardiac Monitoring and Detection of Atrial Fibrillation in Ischemic Stroke Patients: A Systematic Review and Meta-Analysis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background and Purpose Current guidelines do not provide firm directions on atrial fibrillation (AF) screening after ischemic stroke (IS). We sought to investigate the association of implantable cardiac monitoring (ICM) duration with the yield of AF detection in IS patients. Methods We included studies reporting AF detection rates by ICM in IS patients with negative initial AF screening. We excluded studies reporting prolonged cardiac monitoring with devices other than ICM, not providing AF detection rates or monitoring duration, and reporting overlapping data for the same population. The random-effects model was used for all pooled estimates and meta-regression analyses. Results We included 28 studies (4,531 patients, mean age 65 years). In meta-regression analyses, the proportion of AF detection by ICM was independently associated with monitoring duration (coefficient=0.015; 95% confidence interval [CI], 0.005 to 0.024) and mean patient age (coefficient=0.009; 95% CI, 0.003 to 0.015). No associations were detected with other patient characteristics, including IS subtype (cryptogenic vs. embolic stroke of undetermined source) or time from IS onset to CM implantation. In subgroup analyses, significant differences (P<0.001) in the AF detection rates were found for ICM duration (<6 months: 5% [95% CI, 3% to 6%]; ≥6 and ≤12 months: 21% [95% CI, 16% to 25%]; <12 and ≤24 months: 26% [95% CI, 22% to 31%]; <24 months: 34% [95% CI, 29% to 39%]). Conclusions Extended duration of ICM monitoring and increased patient age are factors that substantially increase AF detection in IS patients with initial negative AF screening. atrial fibrillation stroke monitoring meta-analysis Diseases of the circulatory (Cardiovascular) system Aristeidis H. Katsanos verfasserin aut Martin Köhrmann verfasserin aut Valeria Caso verfasserin aut Fabienne Perren verfasserin aut Lina Palaiodimou verfasserin aut Spyridon Deftereos verfasserin aut Sotirios Giannopoulos verfasserin aut John Ellul verfasserin aut Christos Krogias verfasserin aut Dimitris Mavridis verfasserin aut Sokratis Triantafyllou verfasserin aut Anne W. Alexandrov verfasserin aut Peter D. Schellinger verfasserin aut Andrei V. Alexandrov verfasserin aut In Journal of Stroke Korean Stroke Society, 2020 21(2019), 3, Seite 302-311 (DE-627)820686573 (DE-600)2814366-8 22876405 nnns volume:21 year:2019 number:3 pages:302-311 https://doi.org/10.5853/jos.2019.01067 kostenfrei https://doaj.org/article/705a7b54db6a4a8ea08d97b2a3e9cff1 kostenfrei http://www.j-stroke.org/upload/pdf/jos-2019-01067.pdf kostenfrei https://doaj.org/toc/2287-6391 Journal toc kostenfrei https://doaj.org/toc/2287-6405 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21 2019 3 302-311 |
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10.5853/jos.2019.01067 doi (DE-627)DOAJ008452512 (DE-599)DOAJ705a7b54db6a4a8ea08d97b2a3e9cff1 DE-627 ger DE-627 rakwb eng RC666-701 Georgios Tsivgoulis verfasserin aut Duration of Implantable Cardiac Monitoring and Detection of Atrial Fibrillation in Ischemic Stroke Patients: A Systematic Review and Meta-Analysis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background and Purpose Current guidelines do not provide firm directions on atrial fibrillation (AF) screening after ischemic stroke (IS). We sought to investigate the association of implantable cardiac monitoring (ICM) duration with the yield of AF detection in IS patients. Methods We included studies reporting AF detection rates by ICM in IS patients with negative initial AF screening. We excluded studies reporting prolonged cardiac monitoring with devices other than ICM, not providing AF detection rates or monitoring duration, and reporting overlapping data for the same population. The random-effects model was used for all pooled estimates and meta-regression analyses. Results We included 28 studies (4,531 patients, mean age 65 years). In meta-regression analyses, the proportion of AF detection by ICM was independently associated with monitoring duration (coefficient=0.015; 95% confidence interval [CI], 0.005 to 0.024) and mean patient age (coefficient=0.009; 95% CI, 0.003 to 0.015). No associations were detected with other patient characteristics, including IS subtype (cryptogenic vs. embolic stroke of undetermined source) or time from IS onset to CM implantation. In subgroup analyses, significant differences (P<0.001) in the AF detection rates were found for ICM duration (<6 months: 5% [95% CI, 3% to 6%]; ≥6 and ≤12 months: 21% [95% CI, 16% to 25%]; <12 and ≤24 months: 26% [95% CI, 22% to 31%]; <24 months: 34% [95% CI, 29% to 39%]). Conclusions Extended duration of ICM monitoring and increased patient age are factors that substantially increase AF detection in IS patients with initial negative AF screening. atrial fibrillation stroke monitoring meta-analysis Diseases of the circulatory (Cardiovascular) system Aristeidis H. Katsanos verfasserin aut Martin Köhrmann verfasserin aut Valeria Caso verfasserin aut Fabienne Perren verfasserin aut Lina Palaiodimou verfasserin aut Spyridon Deftereos verfasserin aut Sotirios Giannopoulos verfasserin aut John Ellul verfasserin aut Christos Krogias verfasserin aut Dimitris Mavridis verfasserin aut Sokratis Triantafyllou verfasserin aut Anne W. Alexandrov verfasserin aut Peter D. Schellinger verfasserin aut Andrei V. Alexandrov verfasserin aut In Journal of Stroke Korean Stroke Society, 2020 21(2019), 3, Seite 302-311 (DE-627)820686573 (DE-600)2814366-8 22876405 nnns volume:21 year:2019 number:3 pages:302-311 https://doi.org/10.5853/jos.2019.01067 kostenfrei https://doaj.org/article/705a7b54db6a4a8ea08d97b2a3e9cff1 kostenfrei http://www.j-stroke.org/upload/pdf/jos-2019-01067.pdf kostenfrei https://doaj.org/toc/2287-6391 Journal toc kostenfrei https://doaj.org/toc/2287-6405 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21 2019 3 302-311 |
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Georgios Tsivgoulis @@aut@@ Aristeidis H. Katsanos @@aut@@ Martin Köhrmann @@aut@@ Valeria Caso @@aut@@ Fabienne Perren @@aut@@ Lina Palaiodimou @@aut@@ Spyridon Deftereos @@aut@@ Sotirios Giannopoulos @@aut@@ John Ellul @@aut@@ Christos Krogias @@aut@@ Dimitris Mavridis @@aut@@ Sokratis Triantafyllou @@aut@@ Anne W. Alexandrov @@aut@@ Peter D. Schellinger @@aut@@ Andrei V. Alexandrov @@aut@@ |
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Georgios Tsivgoulis Aristeidis H. Katsanos Martin Köhrmann Valeria Caso Fabienne Perren Lina Palaiodimou Spyridon Deftereos Sotirios Giannopoulos John Ellul Christos Krogias Dimitris Mavridis Sokratis Triantafyllou Anne W. Alexandrov Peter D. Schellinger Andrei V. Alexandrov |
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duration of implantable cardiac monitoring and detection of atrial fibrillation in ischemic stroke patients: a systematic review and meta-analysis |
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Duration of Implantable Cardiac Monitoring and Detection of Atrial Fibrillation in Ischemic Stroke Patients: A Systematic Review and Meta-Analysis |
abstract |
Background and Purpose Current guidelines do not provide firm directions on atrial fibrillation (AF) screening after ischemic stroke (IS). We sought to investigate the association of implantable cardiac monitoring (ICM) duration with the yield of AF detection in IS patients. Methods We included studies reporting AF detection rates by ICM in IS patients with negative initial AF screening. We excluded studies reporting prolonged cardiac monitoring with devices other than ICM, not providing AF detection rates or monitoring duration, and reporting overlapping data for the same population. The random-effects model was used for all pooled estimates and meta-regression analyses. Results We included 28 studies (4,531 patients, mean age 65 years). In meta-regression analyses, the proportion of AF detection by ICM was independently associated with monitoring duration (coefficient=0.015; 95% confidence interval [CI], 0.005 to 0.024) and mean patient age (coefficient=0.009; 95% CI, 0.003 to 0.015). No associations were detected with other patient characteristics, including IS subtype (cryptogenic vs. embolic stroke of undetermined source) or time from IS onset to CM implantation. In subgroup analyses, significant differences (P<0.001) in the AF detection rates were found for ICM duration (<6 months: 5% [95% CI, 3% to 6%]; ≥6 and ≤12 months: 21% [95% CI, 16% to 25%]; <12 and ≤24 months: 26% [95% CI, 22% to 31%]; <24 months: 34% [95% CI, 29% to 39%]). Conclusions Extended duration of ICM monitoring and increased patient age are factors that substantially increase AF detection in IS patients with initial negative AF screening. |
abstractGer |
Background and Purpose Current guidelines do not provide firm directions on atrial fibrillation (AF) screening after ischemic stroke (IS). We sought to investigate the association of implantable cardiac monitoring (ICM) duration with the yield of AF detection in IS patients. Methods We included studies reporting AF detection rates by ICM in IS patients with negative initial AF screening. We excluded studies reporting prolonged cardiac monitoring with devices other than ICM, not providing AF detection rates or monitoring duration, and reporting overlapping data for the same population. The random-effects model was used for all pooled estimates and meta-regression analyses. Results We included 28 studies (4,531 patients, mean age 65 years). In meta-regression analyses, the proportion of AF detection by ICM was independently associated with monitoring duration (coefficient=0.015; 95% confidence interval [CI], 0.005 to 0.024) and mean patient age (coefficient=0.009; 95% CI, 0.003 to 0.015). No associations were detected with other patient characteristics, including IS subtype (cryptogenic vs. embolic stroke of undetermined source) or time from IS onset to CM implantation. In subgroup analyses, significant differences (P<0.001) in the AF detection rates were found for ICM duration (<6 months: 5% [95% CI, 3% to 6%]; ≥6 and ≤12 months: 21% [95% CI, 16% to 25%]; <12 and ≤24 months: 26% [95% CI, 22% to 31%]; <24 months: 34% [95% CI, 29% to 39%]). Conclusions Extended duration of ICM monitoring and increased patient age are factors that substantially increase AF detection in IS patients with initial negative AF screening. |
abstract_unstemmed |
Background and Purpose Current guidelines do not provide firm directions on atrial fibrillation (AF) screening after ischemic stroke (IS). We sought to investigate the association of implantable cardiac monitoring (ICM) duration with the yield of AF detection in IS patients. Methods We included studies reporting AF detection rates by ICM in IS patients with negative initial AF screening. We excluded studies reporting prolonged cardiac monitoring with devices other than ICM, not providing AF detection rates or monitoring duration, and reporting overlapping data for the same population. The random-effects model was used for all pooled estimates and meta-regression analyses. Results We included 28 studies (4,531 patients, mean age 65 years). In meta-regression analyses, the proportion of AF detection by ICM was independently associated with monitoring duration (coefficient=0.015; 95% confidence interval [CI], 0.005 to 0.024) and mean patient age (coefficient=0.009; 95% CI, 0.003 to 0.015). No associations were detected with other patient characteristics, including IS subtype (cryptogenic vs. embolic stroke of undetermined source) or time from IS onset to CM implantation. In subgroup analyses, significant differences (P<0.001) in the AF detection rates were found for ICM duration (<6 months: 5% [95% CI, 3% to 6%]; ≥6 and ≤12 months: 21% [95% CI, 16% to 25%]; <12 and ≤24 months: 26% [95% CI, 22% to 31%]; <24 months: 34% [95% CI, 29% to 39%]). Conclusions Extended duration of ICM monitoring and increased patient age are factors that substantially increase AF detection in IS patients with initial negative AF screening. |
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Duration of Implantable Cardiac Monitoring and Detection of Atrial Fibrillation in Ischemic Stroke Patients: A Systematic Review and Meta-Analysis |
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