TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue

White adipose tissue can undergo a process of beiging and acquire functional characteristics similar to brown adipose tissue, including the ability to dissipate energy via uncoupled respiration. Here, Velazquez-Villegas et al. show that activation of the bile acid membrane receptor, TGR5, leads to w...
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Autor*in:	Laura A. Velazquez-Villegas [verfasserIn] Alessia Perino [verfasserIn] Vera Lemos [verfasserIn] Marika Zietak [verfasserIn] Mitsunori Nomura [verfasserIn] Thijs Willem Hendrik Pols [verfasserIn] Kristina Schoonjans [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2018

Übergeordnetes Werk:	In: Nature Communications - Nature Portfolio, 2016, 9(2018), 1, Seite 13
Übergeordnetes Werk:	volume:9 ; year:2018 ; number:1 ; pages:13

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1038/s41467-017-02068-0

Katalog-ID:	DOAJ008522707

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author	Laura A. Velazquez-Villegas
spellingShingle	Laura A. Velazquez-Villegas misc Science misc Q TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue
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topic_title	TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue
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title	TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue
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title_full	TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue
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author_browse	Laura A. Velazquez-Villegas Alessia Perino Vera Lemos Marika Zietak Mitsunori Nomura Thijs Willem Hendrik Pols Kristina Schoonjans
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title_sort	tgr5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue
title_auth	TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue
abstract	White adipose tissue can undergo a process of beiging and acquire functional characteristics similar to brown adipose tissue, including the ability to dissipate energy via uncoupled respiration. Here, Velazquez-Villegas et al. show that activation of the bile acid membrane receptor, TGR5, leads to white adipocyte beiging by promoting mitochondrial fission.
abstractGer	White adipose tissue can undergo a process of beiging and acquire functional characteristics similar to brown adipose tissue, including the ability to dissipate energy via uncoupled respiration. Here, Velazquez-Villegas et al. show that activation of the bile acid membrane receptor, TGR5, leads to white adipocyte beiging by promoting mitochondrial fission.
abstract_unstemmed	White adipose tissue can undergo a process of beiging and acquire functional characteristics similar to brown adipose tissue, including the ability to dissipate energy via uncoupled respiration. Here, Velazquez-Villegas et al. show that activation of the bile acid membrane receptor, TGR5, leads to white adipocyte beiging by promoting mitochondrial fission.
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title_short	TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue
url	https://doi.org/10.1038/s41467-017-02068-0 https://doaj.org/article/bce118ad1a8c4d168d327a80b1fb7582 https://doaj.org/toc/2041-1723
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