Hepatic arginase 2 (Arg2) is sufficient to convey the therapeutic metabolic effects of fasting

Fasting is known for its beneficial effects on obesity and diabetes-related health complications. Here Zhang et al. show that fasting induces expression of arginase-2 (Arg2) in the liver, and that hepatic Arg2, by suppressing the expression of the regulator of G-protein signalling 16, recapitulates...
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Autor*in:	Yiming Zhang [verfasserIn] Cassandra B. Higgins [verfasserIn] Hannah M. Fortune [verfasserIn] Phillip Chen [verfasserIn] Alicyn I. Stothard [verfasserIn] Allyson L. Mayer [verfasserIn] Benjamin M. Swarts [verfasserIn] Brian J. DeBosch [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Übergeordnetes Werk:	In: Nature Communications - Nature Portfolio, 2016, 10(2019), 1, Seite 16
Übergeordnetes Werk:	volume:10 ; year:2019 ; number:1 ; pages:16

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1038/s41467-019-09642-8

Katalog-ID:	DOAJ008973423

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author	Yiming Zhang
spellingShingle	Yiming Zhang misc Science misc Q Hepatic arginase 2 (Arg2) is sufficient to convey the therapeutic metabolic effects of fasting
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topic_title	Hepatic arginase 2 (Arg2) is sufficient to convey the therapeutic metabolic effects of fasting
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title	Hepatic arginase 2 (Arg2) is sufficient to convey the therapeutic metabolic effects of fasting
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author_browse	Yiming Zhang Cassandra B. Higgins Hannah M. Fortune Phillip Chen Alicyn I. Stothard Allyson L. Mayer Benjamin M. Swarts Brian J. DeBosch
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title_sort	hepatic arginase 2 (arg2) is sufficient to convey the therapeutic metabolic effects of fasting
title_auth	Hepatic arginase 2 (Arg2) is sufficient to convey the therapeutic metabolic effects of fasting
abstract	Fasting is known for its beneficial effects on obesity and diabetes-related health complications. Here Zhang et al. show that fasting induces expression of arginase-2 (Arg2) in the liver, and that hepatic Arg2, by suppressing the expression of the regulator of G-protein signalling 16, recapitulates the positive effects of fasting in obesity and diabetes.
abstractGer	Fasting is known for its beneficial effects on obesity and diabetes-related health complications. Here Zhang et al. show that fasting induces expression of arginase-2 (Arg2) in the liver, and that hepatic Arg2, by suppressing the expression of the regulator of G-protein signalling 16, recapitulates the positive effects of fasting in obesity and diabetes.
abstract_unstemmed	Fasting is known for its beneficial effects on obesity and diabetes-related health complications. Here Zhang et al. show that fasting induces expression of arginase-2 (Arg2) in the liver, and that hepatic Arg2, by suppressing the expression of the regulator of G-protein signalling 16, recapitulates the positive effects of fasting in obesity and diabetes.
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title_short	Hepatic arginase 2 (Arg2) is sufficient to convey the therapeutic metabolic effects of fasting
url	https://doi.org/10.1038/s41467-019-09642-8 https://doaj.org/article/954749bafaf0425d8c21a4c09fdcf947 https://doaj.org/toc/2041-1723
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