Post-radiation epithelioid angiosarcoma of the bladder: A true pathological diagnostic challenge
Primary angiosarcomas of the bladder are rare tumors of middle-aged and elderly men that typically present with advanced disease. The association of angiosarcoma with therapeutic radiation has been described. Microscopically it consists of atypical anastomosing vascular channels. It is not uncommon...
Ausführliche Beschreibung
Autor*in: |
Filosa Alessandra [verfasserIn] Collina Guido [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2020 |
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Übergeordnetes Werk: |
In: Human Pathology: Case Reports - Elsevier, 2016, 22(2020), Seite 200430- |
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Übergeordnetes Werk: |
volume:22 ; year:2020 ; pages:200430- |
Links: |
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DOI / URN: |
10.1016/j.ehpc.2020.200430 |
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Katalog-ID: |
DOAJ009025227 |
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10.1016/j.ehpc.2020.200430 doi (DE-627)DOAJ009025227 (DE-599)DOAJb3aa5d8cc4f84aeeba1efd0eda8b96fc DE-627 ger DE-627 rakwb eng RB1-214 Filosa Alessandra verfasserin aut Post-radiation epithelioid angiosarcoma of the bladder: A true pathological diagnostic challenge 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Primary angiosarcomas of the bladder are rare tumors of middle-aged and elderly men that typically present with advanced disease. The association of angiosarcoma with therapeutic radiation has been described. Microscopically it consists of atypical anastomosing vascular channels. It is not uncommon for this tumor to dedifferentiate and form sheets of primitive cells, spindle cells and epithelioid cells. Awareness of the histopathologic spectrum of angiosarcoma is important for the correct diagnosis. Immunohistochemical positivity for vascular markers, including CD31, CD34, ERG, and factor VIII is essential. We report a case of bladder angiosarcoma arisen after pelvic irradiation for prostate carcinoma and diagnosed after a bone marrow trephine biopsy. Radiation therapy Epithelioid angiosarcoma Pathology Collina Guido verfasserin aut In Human Pathology: Case Reports Elsevier, 2016 22(2020), Seite 200430- (DE-627)835590143 (DE-600)2834872-2 22143300 nnns volume:22 year:2020 pages:200430- https://doi.org/10.1016/j.ehpc.2020.200430 kostenfrei https://doaj.org/article/b3aa5d8cc4f84aeeba1efd0eda8b96fc kostenfrei http://www.sciencedirect.com/science/article/pii/S2214330020300791 kostenfrei https://doaj.org/toc/2214-3300 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 22 2020 200430- |
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Primary angiosarcomas of the bladder are rare tumors of middle-aged and elderly men that typically present with advanced disease. The association of angiosarcoma with therapeutic radiation has been described. Microscopically it consists of atypical anastomosing vascular channels. It is not uncommon for this tumor to dedifferentiate and form sheets of primitive cells, spindle cells and epithelioid cells. Awareness of the histopathologic spectrum of angiosarcoma is important for the correct diagnosis. Immunohistochemical positivity for vascular markers, including CD31, CD34, ERG, and factor VIII is essential. We report a case of bladder angiosarcoma arisen after pelvic irradiation for prostate carcinoma and diagnosed after a bone marrow trephine biopsy. |
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Primary angiosarcomas of the bladder are rare tumors of middle-aged and elderly men that typically present with advanced disease. The association of angiosarcoma with therapeutic radiation has been described. Microscopically it consists of atypical anastomosing vascular channels. It is not uncommon for this tumor to dedifferentiate and form sheets of primitive cells, spindle cells and epithelioid cells. Awareness of the histopathologic spectrum of angiosarcoma is important for the correct diagnosis. Immunohistochemical positivity for vascular markers, including CD31, CD34, ERG, and factor VIII is essential. We report a case of bladder angiosarcoma arisen after pelvic irradiation for prostate carcinoma and diagnosed after a bone marrow trephine biopsy. |
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Primary angiosarcomas of the bladder are rare tumors of middle-aged and elderly men that typically present with advanced disease. The association of angiosarcoma with therapeutic radiation has been described. Microscopically it consists of atypical anastomosing vascular channels. It is not uncommon for this tumor to dedifferentiate and form sheets of primitive cells, spindle cells and epithelioid cells. Awareness of the histopathologic spectrum of angiosarcoma is important for the correct diagnosis. Immunohistochemical positivity for vascular markers, including CD31, CD34, ERG, and factor VIII is essential. We report a case of bladder angiosarcoma arisen after pelvic irradiation for prostate carcinoma and diagnosed after a bone marrow trephine biopsy. |
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