Synchronous invasive or preinvasive bronchial lesions detected by autofluorescence bronchoscopy in patients with lung cancer

Objectives: In support with field cancerization theory, some patients with lung cancer (LC) will also have synchronous invasive or pre-invasive bronchial lesions. In this cross sectional – analytic study autofluorescence bronchoscopy (AFB) was used to assess the prevalence of synchronous lesions in...
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Gespeichert in:

Autor*in:	Mohamed Alaa Rashad Mahmoud [verfasserIn] Ali Abdel-azim [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2013

Schlagwörter:	Lung cancer Synchronous Preinvasive bronchial lesions

Übergeordnetes Werk:	In: Egyptian Journal of Chest Disease and Tuberculosis - Wolters Kluwer Medknow Publications, 2016, 62(2013), 4, Seite 713-716
Übergeordnetes Werk:	volume:62 ; year:2013 ; number:4 ; pages:713-716

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1016/j.ejcdt.2013.08.013

Katalog-ID:	DOAJ009303499

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520			\|a Objectives: In support with field cancerization theory, some patients with lung cancer (LC) will also have synchronous invasive or pre-invasive bronchial lesions. In this cross sectional – analytic study autofluorescence bronchoscopy (AFB) was used to assess the prevalence of synchronous lesions in patients with LC. Materials and methods: All patients with abnormal sputum cytology underwent white light and AFB. From 335 patients with abnormal sputum cytology referred for AFB, lung cancer was detected in 91 patients (89 male and 2 female) of age (mean ± SD), 67 ± 8 years. 77 had squamous cell carcinoma (SqCC), 13 had adenocarcinoma and one patient with small cell lung cancer (SCLC). Results: Synchronous lesions detected in 26 (29%) patients, 25 (33%) of patients with SqCC, one with adenocarcinoma, no synchronous lesion detected in one patient with SCLC. The most severe detected synchronous lesion was adenocarcinoma in one patient, Carcinoma insitu (CIS) in 4 patients, severe dysplasia in 3 patients, moderate dysplasia in 10 patients, and mild dysplasia in 8 patients. Synchronous lesions were more frequently detected in current smokers (35%), than in ex-smokers (20%) and non-smokers (15%). Conclusion: Synchronous preinvasive lesions are frequent in patients with LC and AFB should be included in pre-operative evaluation of these patients.
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language	English
source	In Egyptian Journal of Chest Disease and Tuberculosis 62(2013), 4, Seite 713-716 volume:62 year:2013 number:4 pages:713-716
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callnumber-first	R - Medicine
author	Mohamed Alaa Rashad Mahmoud
spellingShingle	Mohamed Alaa Rashad Mahmoud misc RC705-779 misc Lung cancer misc Synchronous misc Preinvasive bronchial lesions misc Diseases of the respiratory system Synchronous invasive or preinvasive bronchial lesions detected by autofluorescence bronchoscopy in patients with lung cancer
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topic_title	RC705-779 Synchronous invasive or preinvasive bronchial lesions detected by autofluorescence bronchoscopy in patients with lung cancer Lung cancer Synchronous Preinvasive bronchial lesions
topic	misc RC705-779 misc Lung cancer misc Synchronous misc Preinvasive bronchial lesions misc Diseases of the respiratory system
topic_unstemmed	misc RC705-779 misc Lung cancer misc Synchronous misc Preinvasive bronchial lesions misc Diseases of the respiratory system
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title	Synchronous invasive or preinvasive bronchial lesions detected by autofluorescence bronchoscopy in patients with lung cancer
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title_full	Synchronous invasive or preinvasive bronchial lesions detected by autofluorescence bronchoscopy in patients with lung cancer
author_sort	Mohamed Alaa Rashad Mahmoud
journal	Egyptian Journal of Chest Disease and Tuberculosis
journalStr	Egyptian Journal of Chest Disease and Tuberculosis
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author_browse	Mohamed Alaa Rashad Mahmoud Ali Abdel-azim
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author-letter	Mohamed Alaa Rashad Mahmoud
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title_sort	synchronous invasive or preinvasive bronchial lesions detected by autofluorescence bronchoscopy in patients with lung cancer
callnumber	RC705-779
title_auth	Synchronous invasive or preinvasive bronchial lesions detected by autofluorescence bronchoscopy in patients with lung cancer
abstract	Objectives: In support with field cancerization theory, some patients with lung cancer (LC) will also have synchronous invasive or pre-invasive bronchial lesions. In this cross sectional – analytic study autofluorescence bronchoscopy (AFB) was used to assess the prevalence of synchronous lesions in patients with LC. Materials and methods: All patients with abnormal sputum cytology underwent white light and AFB. From 335 patients with abnormal sputum cytology referred for AFB, lung cancer was detected in 91 patients (89 male and 2 female) of age (mean ± SD), 67 ± 8 years. 77 had squamous cell carcinoma (SqCC), 13 had adenocarcinoma and one patient with small cell lung cancer (SCLC). Results: Synchronous lesions detected in 26 (29%) patients, 25 (33%) of patients with SqCC, one with adenocarcinoma, no synchronous lesion detected in one patient with SCLC. The most severe detected synchronous lesion was adenocarcinoma in one patient, Carcinoma insitu (CIS) in 4 patients, severe dysplasia in 3 patients, moderate dysplasia in 10 patients, and mild dysplasia in 8 patients. Synchronous lesions were more frequently detected in current smokers (35%), than in ex-smokers (20%) and non-smokers (15%). Conclusion: Synchronous preinvasive lesions are frequent in patients with LC and AFB should be included in pre-operative evaluation of these patients.
abstractGer	Objectives: In support with field cancerization theory, some patients with lung cancer (LC) will also have synchronous invasive or pre-invasive bronchial lesions. In this cross sectional – analytic study autofluorescence bronchoscopy (AFB) was used to assess the prevalence of synchronous lesions in patients with LC. Materials and methods: All patients with abnormal sputum cytology underwent white light and AFB. From 335 patients with abnormal sputum cytology referred for AFB, lung cancer was detected in 91 patients (89 male and 2 female) of age (mean ± SD), 67 ± 8 years. 77 had squamous cell carcinoma (SqCC), 13 had adenocarcinoma and one patient with small cell lung cancer (SCLC). Results: Synchronous lesions detected in 26 (29%) patients, 25 (33%) of patients with SqCC, one with adenocarcinoma, no synchronous lesion detected in one patient with SCLC. The most severe detected synchronous lesion was adenocarcinoma in one patient, Carcinoma insitu (CIS) in 4 patients, severe dysplasia in 3 patients, moderate dysplasia in 10 patients, and mild dysplasia in 8 patients. Synchronous lesions were more frequently detected in current smokers (35%), than in ex-smokers (20%) and non-smokers (15%). Conclusion: Synchronous preinvasive lesions are frequent in patients with LC and AFB should be included in pre-operative evaluation of these patients.
abstract_unstemmed	Objectives: In support with field cancerization theory, some patients with lung cancer (LC) will also have synchronous invasive or pre-invasive bronchial lesions. In this cross sectional – analytic study autofluorescence bronchoscopy (AFB) was used to assess the prevalence of synchronous lesions in patients with LC. Materials and methods: All patients with abnormal sputum cytology underwent white light and AFB. From 335 patients with abnormal sputum cytology referred for AFB, lung cancer was detected in 91 patients (89 male and 2 female) of age (mean ± SD), 67 ± 8 years. 77 had squamous cell carcinoma (SqCC), 13 had adenocarcinoma and one patient with small cell lung cancer (SCLC). Results: Synchronous lesions detected in 26 (29%) patients, 25 (33%) of patients with SqCC, one with adenocarcinoma, no synchronous lesion detected in one patient with SCLC. The most severe detected synchronous lesion was adenocarcinoma in one patient, Carcinoma insitu (CIS) in 4 patients, severe dysplasia in 3 patients, moderate dysplasia in 10 patients, and mild dysplasia in 8 patients. Synchronous lesions were more frequently detected in current smokers (35%), than in ex-smokers (20%) and non-smokers (15%). Conclusion: Synchronous preinvasive lesions are frequent in patients with LC and AFB should be included in pre-operative evaluation of these patients.
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title_short	Synchronous invasive or preinvasive bronchial lesions detected by autofluorescence bronchoscopy in patients with lung cancer
url	https://doi.org/10.1016/j.ejcdt.2013.08.013 https://doaj.org/article/3c75b0bfdd764164b3f1a6729a19526d http://www.sciencedirect.com/science/article/pii/S0422763813001891 https://doaj.org/toc/0422-7638
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up_date	2024-07-03T23:01:26.627Z
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Synchronous invasive or preinvasive bronchial lesions detected by autofluorescence bronchoscopy in patients with lung cancer

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