Curative effect of intravitreal injection of Conbercept on BRVO-ME and influencing factors of best corrected visual acuity after treatment

AIM: To analyze curative effect of intravitreal injection of conbercept on branch retinal vein occlusion(BRVO)with macular edema(ME)and influencing factors of best corrected visual acuity(BCVA)after treatment. <p<METHODS: The clinical efficacy of 194 patients 194 eyes with BRVO-ME who underwen...
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Autor*in:	Jian-Zhi Qiao [verfasserIn] Li Liang [verfasserIn] Hong-Zhou Sun [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Schlagwörter:	conbercept intravitreal injection branch retinal vein occlusion macular edema best corrected visual acuity

Übergeordnetes Werk:	In: Guoji Yanke Zazhi - Press of International Journal of Ophthalmology (IJO PRESS), 2017, 19(2019), 8, Seite 1365-1369
Übergeordnetes Werk:	volume:19 ; year:2019 ; number:8 ; pages:1365-1369

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.3980/j.issn.1672-5123.2019.8.23

Katalog-ID:	DOAJ009338411

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520			\|a AIM: To analyze curative effect of intravitreal injection of conbercept on branch retinal vein occlusion(BRVO)with macular edema(ME)and influencing factors of best corrected visual acuity(BCVA)after treatment. <p<METHODS: The clinical efficacy of 194 patients 194 eyes with BRVO-ME who underwent intravitreal injection of conbercept in the hospital from January 2016 to January 2018 were evaluated. The influencing factors of BCVA after treatment were analyzed by multivariate Logistic regression analysis.<p<RESULTS: The minimum resolution angular logarithm(LogMAR)vision of BCVA and retinal thickness(CMT)of macular fovea of the patients were significantly decreased compared with those before treatment. Although CMT showed a recovery trend at some time nodes, BCVA and CMT at any time point were significantly lower than those before treatment(<i<P</i<<0.05). Multiariable Logistic regression analysis showed that BRVO-ME-ischemic type, type of the ME-hybrid, ELM integrity-missing, missing IS/OS are affected patients with BRVO-ME the vitreous cavity of independent risk factors for compaq heap of injection effect, and the longer the course of the disease and the axial length, BCVA before treatment is higher, the vitreous cavity of treated by injection of compaq heap for the higher risk.<p<CONCLUSION: The curative effect of intravitreal injection of Conbercept is significant on BRVO-ME and safety is good. The poor BCVA recovery in some patients is effected by disease course, BRVO-ME types and other factors. The above factors should be fully evaluated before treatment and active response should be performed, for further optimizing the curative effect.
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653		0	\|a Ophthalmology
700	0		\|a Li Liang \|e verfasserin \|4 aut
700	0		\|a Hong-Zhou Sun \|e verfasserin \|4 aut
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allfields	10.3980/j.issn.1672-5123.2019.8.23 doi (DE-627)DOAJ009338411 (DE-599)DOAJd271b4ba6daf4932a345094c8d873185 DE-627 ger DE-627 rakwb eng RE1-994 Jian-Zhi Qiao verfasserin aut Curative effect of intravitreal injection of Conbercept on BRVO-ME and influencing factors of best corrected visual acuity after treatment 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier AIM: To analyze curative effect of intravitreal injection of conbercept on branch retinal vein occlusion(BRVO)with macular edema(ME)and influencing factors of best corrected visual acuity(BCVA)after treatment. <p<METHODS: The clinical efficacy of 194 patients 194 eyes with BRVO-ME who underwent intravitreal injection of conbercept in the hospital from January 2016 to January 2018 were evaluated. The influencing factors of BCVA after treatment were analyzed by multivariate Logistic regression analysis.<p<RESULTS: The minimum resolution angular logarithm(LogMAR)vision of BCVA and retinal thickness(CMT)of macular fovea of the patients were significantly decreased compared with those before treatment. Although CMT showed a recovery trend at some time nodes, BCVA and CMT at any time point were significantly lower than those before treatment(<i<P</i<<0.05). Multiariable Logistic regression analysis showed that BRVO-ME-ischemic type, type of the ME-hybrid, ELM integrity-missing, missing IS/OS are affected patients with BRVO-ME the vitreous cavity of independent risk factors for compaq heap of injection effect, and the longer the course of the disease and the axial length, BCVA before treatment is higher, the vitreous cavity of treated by injection of compaq heap for the higher risk.<p<CONCLUSION: The curative effect of intravitreal injection of Conbercept is significant on BRVO-ME and safety is good. The poor BCVA recovery in some patients is effected by disease course, BRVO-ME types and other factors. The above factors should be fully evaluated before treatment and active response should be performed, for further optimizing the curative effect. conbercept intravitreal injection branch retinal vein occlusion macular edema best corrected visual acuity Ophthalmology Li Liang verfasserin aut Hong-Zhou Sun verfasserin aut In Guoji Yanke Zazhi Press of International Journal of Ophthalmology (IJO PRESS), 2017 19(2019), 8, Seite 1365-1369 (DE-627)1680946854 16725123 nnns volume:19 year:2019 number:8 pages:1365-1369 https://doi.org/10.3980/j.issn.1672-5123.2019.8.23 kostenfrei https://doaj.org/article/d271b4ba6daf4932a345094c8d873185 kostenfrei http://ies.ijo.cn/cn_publish/2019/8/201908023.pdf kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_2817 AR 19 2019 8 1365-1369
spelling	10.3980/j.issn.1672-5123.2019.8.23 doi (DE-627)DOAJ009338411 (DE-599)DOAJd271b4ba6daf4932a345094c8d873185 DE-627 ger DE-627 rakwb eng RE1-994 Jian-Zhi Qiao verfasserin aut Curative effect of intravitreal injection of Conbercept on BRVO-ME and influencing factors of best corrected visual acuity after treatment 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier AIM: To analyze curative effect of intravitreal injection of conbercept on branch retinal vein occlusion(BRVO)with macular edema(ME)and influencing factors of best corrected visual acuity(BCVA)after treatment. <p<METHODS: The clinical efficacy of 194 patients 194 eyes with BRVO-ME who underwent intravitreal injection of conbercept in the hospital from January 2016 to January 2018 were evaluated. The influencing factors of BCVA after treatment were analyzed by multivariate Logistic regression analysis.<p<RESULTS: The minimum resolution angular logarithm(LogMAR)vision of BCVA and retinal thickness(CMT)of macular fovea of the patients were significantly decreased compared with those before treatment. Although CMT showed a recovery trend at some time nodes, BCVA and CMT at any time point were significantly lower than those before treatment(<i<P</i<<0.05). Multiariable Logistic regression analysis showed that BRVO-ME-ischemic type, type of the ME-hybrid, ELM integrity-missing, missing IS/OS are affected patients with BRVO-ME the vitreous cavity of independent risk factors for compaq heap of injection effect, and the longer the course of the disease and the axial length, BCVA before treatment is higher, the vitreous cavity of treated by injection of compaq heap for the higher risk.<p<CONCLUSION: The curative effect of intravitreal injection of Conbercept is significant on BRVO-ME and safety is good. The poor BCVA recovery in some patients is effected by disease course, BRVO-ME types and other factors. The above factors should be fully evaluated before treatment and active response should be performed, for further optimizing the curative effect. conbercept intravitreal injection branch retinal vein occlusion macular edema best corrected visual acuity Ophthalmology Li Liang verfasserin aut Hong-Zhou Sun verfasserin aut In Guoji Yanke Zazhi Press of International Journal of Ophthalmology (IJO PRESS), 2017 19(2019), 8, Seite 1365-1369 (DE-627)1680946854 16725123 nnns volume:19 year:2019 number:8 pages:1365-1369 https://doi.org/10.3980/j.issn.1672-5123.2019.8.23 kostenfrei https://doaj.org/article/d271b4ba6daf4932a345094c8d873185 kostenfrei http://ies.ijo.cn/cn_publish/2019/8/201908023.pdf kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_2817 AR 19 2019 8 1365-1369
allfields_unstemmed	10.3980/j.issn.1672-5123.2019.8.23 doi (DE-627)DOAJ009338411 (DE-599)DOAJd271b4ba6daf4932a345094c8d873185 DE-627 ger DE-627 rakwb eng RE1-994 Jian-Zhi Qiao verfasserin aut Curative effect of intravitreal injection of Conbercept on BRVO-ME and influencing factors of best corrected visual acuity after treatment 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier AIM: To analyze curative effect of intravitreal injection of conbercept on branch retinal vein occlusion(BRVO)with macular edema(ME)and influencing factors of best corrected visual acuity(BCVA)after treatment. <p<METHODS: The clinical efficacy of 194 patients 194 eyes with BRVO-ME who underwent intravitreal injection of conbercept in the hospital from January 2016 to January 2018 were evaluated. The influencing factors of BCVA after treatment were analyzed by multivariate Logistic regression analysis.<p<RESULTS: The minimum resolution angular logarithm(LogMAR)vision of BCVA and retinal thickness(CMT)of macular fovea of the patients were significantly decreased compared with those before treatment. Although CMT showed a recovery trend at some time nodes, BCVA and CMT at any time point were significantly lower than those before treatment(<i<P</i<<0.05). Multiariable Logistic regression analysis showed that BRVO-ME-ischemic type, type of the ME-hybrid, ELM integrity-missing, missing IS/OS are affected patients with BRVO-ME the vitreous cavity of independent risk factors for compaq heap of injection effect, and the longer the course of the disease and the axial length, BCVA before treatment is higher, the vitreous cavity of treated by injection of compaq heap for the higher risk.<p<CONCLUSION: The curative effect of intravitreal injection of Conbercept is significant on BRVO-ME and safety is good. The poor BCVA recovery in some patients is effected by disease course, BRVO-ME types and other factors. The above factors should be fully evaluated before treatment and active response should be performed, for further optimizing the curative effect. conbercept intravitreal injection branch retinal vein occlusion macular edema best corrected visual acuity Ophthalmology Li Liang verfasserin aut Hong-Zhou Sun verfasserin aut In Guoji Yanke Zazhi Press of International Journal of Ophthalmology (IJO PRESS), 2017 19(2019), 8, Seite 1365-1369 (DE-627)1680946854 16725123 nnns volume:19 year:2019 number:8 pages:1365-1369 https://doi.org/10.3980/j.issn.1672-5123.2019.8.23 kostenfrei https://doaj.org/article/d271b4ba6daf4932a345094c8d873185 kostenfrei http://ies.ijo.cn/cn_publish/2019/8/201908023.pdf kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_2817 AR 19 2019 8 1365-1369
allfieldsGer	10.3980/j.issn.1672-5123.2019.8.23 doi (DE-627)DOAJ009338411 (DE-599)DOAJd271b4ba6daf4932a345094c8d873185 DE-627 ger DE-627 rakwb eng RE1-994 Jian-Zhi Qiao verfasserin aut Curative effect of intravitreal injection of Conbercept on BRVO-ME and influencing factors of best corrected visual acuity after treatment 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier AIM: To analyze curative effect of intravitreal injection of conbercept on branch retinal vein occlusion(BRVO)with macular edema(ME)and influencing factors of best corrected visual acuity(BCVA)after treatment. <p<METHODS: The clinical efficacy of 194 patients 194 eyes with BRVO-ME who underwent intravitreal injection of conbercept in the hospital from January 2016 to January 2018 were evaluated. The influencing factors of BCVA after treatment were analyzed by multivariate Logistic regression analysis.<p<RESULTS: The minimum resolution angular logarithm(LogMAR)vision of BCVA and retinal thickness(CMT)of macular fovea of the patients were significantly decreased compared with those before treatment. Although CMT showed a recovery trend at some time nodes, BCVA and CMT at any time point were significantly lower than those before treatment(<i<P</i<<0.05). Multiariable Logistic regression analysis showed that BRVO-ME-ischemic type, type of the ME-hybrid, ELM integrity-missing, missing IS/OS are affected patients with BRVO-ME the vitreous cavity of independent risk factors for compaq heap of injection effect, and the longer the course of the disease and the axial length, BCVA before treatment is higher, the vitreous cavity of treated by injection of compaq heap for the higher risk.<p<CONCLUSION: The curative effect of intravitreal injection of Conbercept is significant on BRVO-ME and safety is good. The poor BCVA recovery in some patients is effected by disease course, BRVO-ME types and other factors. The above factors should be fully evaluated before treatment and active response should be performed, for further optimizing the curative effect. conbercept intravitreal injection branch retinal vein occlusion macular edema best corrected visual acuity Ophthalmology Li Liang verfasserin aut Hong-Zhou Sun verfasserin aut In Guoji Yanke Zazhi Press of International Journal of Ophthalmology (IJO PRESS), 2017 19(2019), 8, Seite 1365-1369 (DE-627)1680946854 16725123 nnns volume:19 year:2019 number:8 pages:1365-1369 https://doi.org/10.3980/j.issn.1672-5123.2019.8.23 kostenfrei https://doaj.org/article/d271b4ba6daf4932a345094c8d873185 kostenfrei http://ies.ijo.cn/cn_publish/2019/8/201908023.pdf kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_2817 AR 19 2019 8 1365-1369
allfieldsSound	10.3980/j.issn.1672-5123.2019.8.23 doi (DE-627)DOAJ009338411 (DE-599)DOAJd271b4ba6daf4932a345094c8d873185 DE-627 ger DE-627 rakwb eng RE1-994 Jian-Zhi Qiao verfasserin aut Curative effect of intravitreal injection of Conbercept on BRVO-ME and influencing factors of best corrected visual acuity after treatment 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier AIM: To analyze curative effect of intravitreal injection of conbercept on branch retinal vein occlusion(BRVO)with macular edema(ME)and influencing factors of best corrected visual acuity(BCVA)after treatment. <p<METHODS: The clinical efficacy of 194 patients 194 eyes with BRVO-ME who underwent intravitreal injection of conbercept in the hospital from January 2016 to January 2018 were evaluated. The influencing factors of BCVA after treatment were analyzed by multivariate Logistic regression analysis.<p<RESULTS: The minimum resolution angular logarithm(LogMAR)vision of BCVA and retinal thickness(CMT)of macular fovea of the patients were significantly decreased compared with those before treatment. Although CMT showed a recovery trend at some time nodes, BCVA and CMT at any time point were significantly lower than those before treatment(<i<P</i<<0.05). Multiariable Logistic regression analysis showed that BRVO-ME-ischemic type, type of the ME-hybrid, ELM integrity-missing, missing IS/OS are affected patients with BRVO-ME the vitreous cavity of independent risk factors for compaq heap of injection effect, and the longer the course of the disease and the axial length, BCVA before treatment is higher, the vitreous cavity of treated by injection of compaq heap for the higher risk.<p<CONCLUSION: The curative effect of intravitreal injection of Conbercept is significant on BRVO-ME and safety is good. The poor BCVA recovery in some patients is effected by disease course, BRVO-ME types and other factors. The above factors should be fully evaluated before treatment and active response should be performed, for further optimizing the curative effect. conbercept intravitreal injection branch retinal vein occlusion macular edema best corrected visual acuity Ophthalmology Li Liang verfasserin aut Hong-Zhou Sun verfasserin aut In Guoji Yanke Zazhi Press of International Journal of Ophthalmology (IJO PRESS), 2017 19(2019), 8, Seite 1365-1369 (DE-627)1680946854 16725123 nnns volume:19 year:2019 number:8 pages:1365-1369 https://doi.org/10.3980/j.issn.1672-5123.2019.8.23 kostenfrei https://doaj.org/article/d271b4ba6daf4932a345094c8d873185 kostenfrei http://ies.ijo.cn/cn_publish/2019/8/201908023.pdf kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_2817 AR 19 2019 8 1365-1369
language	English
source	In Guoji Yanke Zazhi 19(2019), 8, Seite 1365-1369 volume:19 year:2019 number:8 pages:1365-1369
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institution	findex.gbv.de
topic_facet	conbercept intravitreal injection branch retinal vein occlusion macular edema best corrected visual acuity Ophthalmology
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container_title	Guoji Yanke Zazhi
authorswithroles_txt_mv	Jian-Zhi Qiao @@aut@@ Li Liang @@aut@@ Hong-Zhou Sun @@aut@@
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callnumber-first	R - Medicine
author	Jian-Zhi Qiao
spellingShingle	Jian-Zhi Qiao misc RE1-994 misc conbercept misc intravitreal injection misc branch retinal vein occlusion misc macular edema misc best corrected visual acuity misc Ophthalmology Curative effect of intravitreal injection of Conbercept on BRVO-ME and influencing factors of best corrected visual acuity after treatment
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topic_title	RE1-994 Curative effect of intravitreal injection of Conbercept on BRVO-ME and influencing factors of best corrected visual acuity after treatment conbercept intravitreal injection branch retinal vein occlusion macular edema best corrected visual acuity
topic	misc RE1-994 misc conbercept misc intravitreal injection misc branch retinal vein occlusion misc macular edema misc best corrected visual acuity misc Ophthalmology
topic_unstemmed	misc RE1-994 misc conbercept misc intravitreal injection misc branch retinal vein occlusion misc macular edema misc best corrected visual acuity misc Ophthalmology
topic_browse	misc RE1-994 misc conbercept misc intravitreal injection misc branch retinal vein occlusion misc macular edema misc best corrected visual acuity misc Ophthalmology
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title	Curative effect of intravitreal injection of Conbercept on BRVO-ME and influencing factors of best corrected visual acuity after treatment
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title_full	Curative effect of intravitreal injection of Conbercept on BRVO-ME and influencing factors of best corrected visual acuity after treatment
author_sort	Jian-Zhi Qiao
journal	Guoji Yanke Zazhi
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author_browse	Jian-Zhi Qiao Li Liang Hong-Zhou Sun
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author-letter	Jian-Zhi Qiao
doi_str_mv	10.3980/j.issn.1672-5123.2019.8.23
author2-role	verfasserin
title_sort	curative effect of intravitreal injection of conbercept on brvo-me and influencing factors of best corrected visual acuity after treatment
callnumber	RE1-994
title_auth	Curative effect of intravitreal injection of Conbercept on BRVO-ME and influencing factors of best corrected visual acuity after treatment
abstract	AIM: To analyze curative effect of intravitreal injection of conbercept on branch retinal vein occlusion(BRVO)with macular edema(ME)and influencing factors of best corrected visual acuity(BCVA)after treatment. <p<METHODS: The clinical efficacy of 194 patients 194 eyes with BRVO-ME who underwent intravitreal injection of conbercept in the hospital from January 2016 to January 2018 were evaluated. The influencing factors of BCVA after treatment were analyzed by multivariate Logistic regression analysis.<p<RESULTS: The minimum resolution angular logarithm(LogMAR)vision of BCVA and retinal thickness(CMT)of macular fovea of the patients were significantly decreased compared with those before treatment. Although CMT showed a recovery trend at some time nodes, BCVA and CMT at any time point were significantly lower than those before treatment(<i<P</i<<0.05). Multiariable Logistic regression analysis showed that BRVO-ME-ischemic type, type of the ME-hybrid, ELM integrity-missing, missing IS/OS are affected patients with BRVO-ME the vitreous cavity of independent risk factors for compaq heap of injection effect, and the longer the course of the disease and the axial length, BCVA before treatment is higher, the vitreous cavity of treated by injection of compaq heap for the higher risk.<p<CONCLUSION: The curative effect of intravitreal injection of Conbercept is significant on BRVO-ME and safety is good. The poor BCVA recovery in some patients is effected by disease course, BRVO-ME types and other factors. The above factors should be fully evaluated before treatment and active response should be performed, for further optimizing the curative effect.
abstractGer	AIM: To analyze curative effect of intravitreal injection of conbercept on branch retinal vein occlusion(BRVO)with macular edema(ME)and influencing factors of best corrected visual acuity(BCVA)after treatment. <p<METHODS: The clinical efficacy of 194 patients 194 eyes with BRVO-ME who underwent intravitreal injection of conbercept in the hospital from January 2016 to January 2018 were evaluated. The influencing factors of BCVA after treatment were analyzed by multivariate Logistic regression analysis.<p<RESULTS: The minimum resolution angular logarithm(LogMAR)vision of BCVA and retinal thickness(CMT)of macular fovea of the patients were significantly decreased compared with those before treatment. Although CMT showed a recovery trend at some time nodes, BCVA and CMT at any time point were significantly lower than those before treatment(<i<P</i<<0.05). Multiariable Logistic regression analysis showed that BRVO-ME-ischemic type, type of the ME-hybrid, ELM integrity-missing, missing IS/OS are affected patients with BRVO-ME the vitreous cavity of independent risk factors for compaq heap of injection effect, and the longer the course of the disease and the axial length, BCVA before treatment is higher, the vitreous cavity of treated by injection of compaq heap for the higher risk.<p<CONCLUSION: The curative effect of intravitreal injection of Conbercept is significant on BRVO-ME and safety is good. The poor BCVA recovery in some patients is effected by disease course, BRVO-ME types and other factors. The above factors should be fully evaluated before treatment and active response should be performed, for further optimizing the curative effect.
abstract_unstemmed	AIM: To analyze curative effect of intravitreal injection of conbercept on branch retinal vein occlusion(BRVO)with macular edema(ME)and influencing factors of best corrected visual acuity(BCVA)after treatment. <p<METHODS: The clinical efficacy of 194 patients 194 eyes with BRVO-ME who underwent intravitreal injection of conbercept in the hospital from January 2016 to January 2018 were evaluated. The influencing factors of BCVA after treatment were analyzed by multivariate Logistic regression analysis.<p<RESULTS: The minimum resolution angular logarithm(LogMAR)vision of BCVA and retinal thickness(CMT)of macular fovea of the patients were significantly decreased compared with those before treatment. Although CMT showed a recovery trend at some time nodes, BCVA and CMT at any time point were significantly lower than those before treatment(<i<P</i<<0.05). Multiariable Logistic regression analysis showed that BRVO-ME-ischemic type, type of the ME-hybrid, ELM integrity-missing, missing IS/OS are affected patients with BRVO-ME the vitreous cavity of independent risk factors for compaq heap of injection effect, and the longer the course of the disease and the axial length, BCVA before treatment is higher, the vitreous cavity of treated by injection of compaq heap for the higher risk.<p<CONCLUSION: The curative effect of intravitreal injection of Conbercept is significant on BRVO-ME and safety is good. The poor BCVA recovery in some patients is effected by disease course, BRVO-ME types and other factors. The above factors should be fully evaluated before treatment and active response should be performed, for further optimizing the curative effect.
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title_short	Curative effect of intravitreal injection of Conbercept on BRVO-ME and influencing factors of best corrected visual acuity after treatment
url	https://doi.org/10.3980/j.issn.1672-5123.2019.8.23 https://doaj.org/article/d271b4ba6daf4932a345094c8d873185 http://ies.ijo.cn/cn_publish/2019/8/201908023.pdf https://doaj.org/toc/1672-5123
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doi_str	10.3980/j.issn.1672-5123.2019.8.23
callnumber-a	RE1-994
up_date	2024-07-03T23:11:32.436Z
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