Early multifocal electroretinography findings after intravitreal Conbercept in the treatment of wet age-related macular degeneration
AIM: To evaluate the early changes of retinal function in patients with wet age-related macular degeneration(ARMD)after intravitreal Conbercept treatment by multifocal electroretinography(mfERG). <p<METHODS: Wet ARMD patients diagnosed by fundus fluorescein angiography and received intravitrea...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Ding-Guo Huang [verfasserIn] Jian-Long Zheng [verfasserIn] Guo-Qiao Lin [verfasserIn] Wei-Qi Chen [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2018 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
In: Guoji Yanke Zazhi - Press of International Journal of Ophthalmology (IJO PRESS), 2017, 18(2018), 9, Seite 1692-1695 |
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| Übergeordnetes Werk: |
volume:18 ; year:2018 ; number:9 ; pages:1692-1695 |
| Links: |
Link aufrufen |
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| DOI / URN: |
10.3980/j.issn.1672-5123.2018.9.31 |
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| Katalog-ID: |
DOAJ009766774 |
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| 245 | 1 | 0 | |a Early multifocal electroretinography findings after intravitreal Conbercept in the treatment of wet age-related macular degeneration |
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| 520 | |a AIM: To evaluate the early changes of retinal function in patients with wet age-related macular degeneration(ARMD)after intravitreal Conbercept treatment by multifocal electroretinography(mfERG). <p<METHODS: Wet ARMD patients diagnosed by fundus fluorescein angiography and received intravitreal injection of Conbercept(0.05mL/0.5mg)were included. Best corrected visual acuity(BCVA), incubation of N1, P1 and amplitude of P1 in mfERG test were recorded before and 1mo after treatment. <p<RESULTS: Twenty patients(20 eyes)were enrolled in total. The mean BCVA was 0.80±0.48 LogMAR at baseline and improved to 0.65±0.50 LogMAR after treatment(<i<P</i<<0.001). Mean P1 amplitude density of the mfERG Ring 1 increased from 39.59±16.60nV/deg<sup<2</sup< to 53.81±20.41nV/deg<sup<2</sup<(<i<P</i<=0.006). The change in visual acuity was positively correlated with the change in P1 amplitude density of Ring 1(<i<r</i<=-0.776, <i<P</i<<0.001). <p<CONCLUSION: Intravitreal conbercept injection can improve the central retinal function of wet ARMD patients in the short term. | ||
| 650 | 4 | |a multifocal electroretinography | |
| 650 | 4 | |a conbercept | |
| 650 | 4 | |a wet age-related macular degeneration | |
| 653 | 0 | |a Ophthalmology | |
| 700 | 0 | |a Jian-Long Zheng |e verfasserin |4 aut | |
| 700 | 0 | |a Guo-Qiao Lin |e verfasserin |4 aut | |
| 700 | 0 | |a Wei-Qi Chen |e verfasserin |4 aut | |
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10.3980/j.issn.1672-5123.2018.9.31 doi (DE-627)DOAJ009766774 (DE-599)DOAJ84c364a7cfe9494aa94eacc510e69478 DE-627 ger DE-627 rakwb eng RE1-994 Ding-Guo Huang verfasserin aut Early multifocal electroretinography findings after intravitreal Conbercept in the treatment of wet age-related macular degeneration 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier AIM: To evaluate the early changes of retinal function in patients with wet age-related macular degeneration(ARMD)after intravitreal Conbercept treatment by multifocal electroretinography(mfERG). <p<METHODS: Wet ARMD patients diagnosed by fundus fluorescein angiography and received intravitreal injection of Conbercept(0.05mL/0.5mg)were included. Best corrected visual acuity(BCVA), incubation of N1, P1 and amplitude of P1 in mfERG test were recorded before and 1mo after treatment. <p<RESULTS: Twenty patients(20 eyes)were enrolled in total. The mean BCVA was 0.80±0.48 LogMAR at baseline and improved to 0.65±0.50 LogMAR after treatment(<i<P</i<<0.001). Mean P1 amplitude density of the mfERG Ring 1 increased from 39.59±16.60nV/deg<sup<2</sup< to 53.81±20.41nV/deg<sup<2</sup<(<i<P</i<=0.006). The change in visual acuity was positively correlated with the change in P1 amplitude density of Ring 1(<i<r</i<=-0.776, <i<P</i<<0.001). <p<CONCLUSION: Intravitreal conbercept injection can improve the central retinal function of wet ARMD patients in the short term. multifocal electroretinography conbercept wet age-related macular degeneration Ophthalmology Jian-Long Zheng verfasserin aut Guo-Qiao Lin verfasserin aut Wei-Qi Chen verfasserin aut In Guoji Yanke Zazhi Press of International Journal of Ophthalmology (IJO PRESS), 2017 18(2018), 9, Seite 1692-1695 (DE-627)1680946854 16725123 nnns volume:18 year:2018 number:9 pages:1692-1695 https://doi.org/10.3980/j.issn.1672-5123.2018.9.31 kostenfrei https://doaj.org/article/84c364a7cfe9494aa94eacc510e69478 kostenfrei http://ies.ijo.cn/cn_publish/2018/9/201809031.pdf kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_2817 AR 18 2018 9 1692-1695 |
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10.3980/j.issn.1672-5123.2018.9.31 doi (DE-627)DOAJ009766774 (DE-599)DOAJ84c364a7cfe9494aa94eacc510e69478 DE-627 ger DE-627 rakwb eng RE1-994 Ding-Guo Huang verfasserin aut Early multifocal electroretinography findings after intravitreal Conbercept in the treatment of wet age-related macular degeneration 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier AIM: To evaluate the early changes of retinal function in patients with wet age-related macular degeneration(ARMD)after intravitreal Conbercept treatment by multifocal electroretinography(mfERG). <p<METHODS: Wet ARMD patients diagnosed by fundus fluorescein angiography and received intravitreal injection of Conbercept(0.05mL/0.5mg)were included. Best corrected visual acuity(BCVA), incubation of N1, P1 and amplitude of P1 in mfERG test were recorded before and 1mo after treatment. <p<RESULTS: Twenty patients(20 eyes)were enrolled in total. The mean BCVA was 0.80±0.48 LogMAR at baseline and improved to 0.65±0.50 LogMAR after treatment(<i<P</i<<0.001). Mean P1 amplitude density of the mfERG Ring 1 increased from 39.59±16.60nV/deg<sup<2</sup< to 53.81±20.41nV/deg<sup<2</sup<(<i<P</i<=0.006). The change in visual acuity was positively correlated with the change in P1 amplitude density of Ring 1(<i<r</i<=-0.776, <i<P</i<<0.001). <p<CONCLUSION: Intravitreal conbercept injection can improve the central retinal function of wet ARMD patients in the short term. multifocal electroretinography conbercept wet age-related macular degeneration Ophthalmology Jian-Long Zheng verfasserin aut Guo-Qiao Lin verfasserin aut Wei-Qi Chen verfasserin aut In Guoji Yanke Zazhi Press of International Journal of Ophthalmology (IJO PRESS), 2017 18(2018), 9, Seite 1692-1695 (DE-627)1680946854 16725123 nnns volume:18 year:2018 number:9 pages:1692-1695 https://doi.org/10.3980/j.issn.1672-5123.2018.9.31 kostenfrei https://doaj.org/article/84c364a7cfe9494aa94eacc510e69478 kostenfrei http://ies.ijo.cn/cn_publish/2018/9/201809031.pdf kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_2817 AR 18 2018 9 1692-1695 |
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10.3980/j.issn.1672-5123.2018.9.31 doi (DE-627)DOAJ009766774 (DE-599)DOAJ84c364a7cfe9494aa94eacc510e69478 DE-627 ger DE-627 rakwb eng RE1-994 Ding-Guo Huang verfasserin aut Early multifocal electroretinography findings after intravitreal Conbercept in the treatment of wet age-related macular degeneration 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier AIM: To evaluate the early changes of retinal function in patients with wet age-related macular degeneration(ARMD)after intravitreal Conbercept treatment by multifocal electroretinography(mfERG). <p<METHODS: Wet ARMD patients diagnosed by fundus fluorescein angiography and received intravitreal injection of Conbercept(0.05mL/0.5mg)were included. Best corrected visual acuity(BCVA), incubation of N1, P1 and amplitude of P1 in mfERG test were recorded before and 1mo after treatment. <p<RESULTS: Twenty patients(20 eyes)were enrolled in total. The mean BCVA was 0.80±0.48 LogMAR at baseline and improved to 0.65±0.50 LogMAR after treatment(<i<P</i<<0.001). Mean P1 amplitude density of the mfERG Ring 1 increased from 39.59±16.60nV/deg<sup<2</sup< to 53.81±20.41nV/deg<sup<2</sup<(<i<P</i<=0.006). The change in visual acuity was positively correlated with the change in P1 amplitude density of Ring 1(<i<r</i<=-0.776, <i<P</i<<0.001). <p<CONCLUSION: Intravitreal conbercept injection can improve the central retinal function of wet ARMD patients in the short term. multifocal electroretinography conbercept wet age-related macular degeneration Ophthalmology Jian-Long Zheng verfasserin aut Guo-Qiao Lin verfasserin aut Wei-Qi Chen verfasserin aut In Guoji Yanke Zazhi Press of International Journal of Ophthalmology (IJO PRESS), 2017 18(2018), 9, Seite 1692-1695 (DE-627)1680946854 16725123 nnns volume:18 year:2018 number:9 pages:1692-1695 https://doi.org/10.3980/j.issn.1672-5123.2018.9.31 kostenfrei https://doaj.org/article/84c364a7cfe9494aa94eacc510e69478 kostenfrei http://ies.ijo.cn/cn_publish/2018/9/201809031.pdf kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_2817 AR 18 2018 9 1692-1695 |
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10.3980/j.issn.1672-5123.2018.9.31 doi (DE-627)DOAJ009766774 (DE-599)DOAJ84c364a7cfe9494aa94eacc510e69478 DE-627 ger DE-627 rakwb eng RE1-994 Ding-Guo Huang verfasserin aut Early multifocal electroretinography findings after intravitreal Conbercept in the treatment of wet age-related macular degeneration 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier AIM: To evaluate the early changes of retinal function in patients with wet age-related macular degeneration(ARMD)after intravitreal Conbercept treatment by multifocal electroretinography(mfERG). <p<METHODS: Wet ARMD patients diagnosed by fundus fluorescein angiography and received intravitreal injection of Conbercept(0.05mL/0.5mg)were included. Best corrected visual acuity(BCVA), incubation of N1, P1 and amplitude of P1 in mfERG test were recorded before and 1mo after treatment. <p<RESULTS: Twenty patients(20 eyes)were enrolled in total. The mean BCVA was 0.80±0.48 LogMAR at baseline and improved to 0.65±0.50 LogMAR after treatment(<i<P</i<<0.001). Mean P1 amplitude density of the mfERG Ring 1 increased from 39.59±16.60nV/deg<sup<2</sup< to 53.81±20.41nV/deg<sup<2</sup<(<i<P</i<=0.006). The change in visual acuity was positively correlated with the change in P1 amplitude density of Ring 1(<i<r</i<=-0.776, <i<P</i<<0.001). <p<CONCLUSION: Intravitreal conbercept injection can improve the central retinal function of wet ARMD patients in the short term. multifocal electroretinography conbercept wet age-related macular degeneration Ophthalmology Jian-Long Zheng verfasserin aut Guo-Qiao Lin verfasserin aut Wei-Qi Chen verfasserin aut In Guoji Yanke Zazhi Press of International Journal of Ophthalmology (IJO PRESS), 2017 18(2018), 9, Seite 1692-1695 (DE-627)1680946854 16725123 nnns volume:18 year:2018 number:9 pages:1692-1695 https://doi.org/10.3980/j.issn.1672-5123.2018.9.31 kostenfrei https://doaj.org/article/84c364a7cfe9494aa94eacc510e69478 kostenfrei http://ies.ijo.cn/cn_publish/2018/9/201809031.pdf kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_2817 AR 18 2018 9 1692-1695 |
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10.3980/j.issn.1672-5123.2018.9.31 doi (DE-627)DOAJ009766774 (DE-599)DOAJ84c364a7cfe9494aa94eacc510e69478 DE-627 ger DE-627 rakwb eng RE1-994 Ding-Guo Huang verfasserin aut Early multifocal electroretinography findings after intravitreal Conbercept in the treatment of wet age-related macular degeneration 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier AIM: To evaluate the early changes of retinal function in patients with wet age-related macular degeneration(ARMD)after intravitreal Conbercept treatment by multifocal electroretinography(mfERG). <p<METHODS: Wet ARMD patients diagnosed by fundus fluorescein angiography and received intravitreal injection of Conbercept(0.05mL/0.5mg)were included. Best corrected visual acuity(BCVA), incubation of N1, P1 and amplitude of P1 in mfERG test were recorded before and 1mo after treatment. <p<RESULTS: Twenty patients(20 eyes)were enrolled in total. The mean BCVA was 0.80±0.48 LogMAR at baseline and improved to 0.65±0.50 LogMAR after treatment(<i<P</i<<0.001). Mean P1 amplitude density of the mfERG Ring 1 increased from 39.59±16.60nV/deg<sup<2</sup< to 53.81±20.41nV/deg<sup<2</sup<(<i<P</i<=0.006). The change in visual acuity was positively correlated with the change in P1 amplitude density of Ring 1(<i<r</i<=-0.776, <i<P</i<<0.001). <p<CONCLUSION: Intravitreal conbercept injection can improve the central retinal function of wet ARMD patients in the short term. multifocal electroretinography conbercept wet age-related macular degeneration Ophthalmology Jian-Long Zheng verfasserin aut Guo-Qiao Lin verfasserin aut Wei-Qi Chen verfasserin aut In Guoji Yanke Zazhi Press of International Journal of Ophthalmology (IJO PRESS), 2017 18(2018), 9, Seite 1692-1695 (DE-627)1680946854 16725123 nnns volume:18 year:2018 number:9 pages:1692-1695 https://doi.org/10.3980/j.issn.1672-5123.2018.9.31 kostenfrei https://doaj.org/article/84c364a7cfe9494aa94eacc510e69478 kostenfrei http://ies.ijo.cn/cn_publish/2018/9/201809031.pdf kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_2817 AR 18 2018 9 1692-1695 |
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Ding-Guo Huang |
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Ding-Guo Huang misc RE1-994 misc multifocal electroretinography misc conbercept misc wet age-related macular degeneration misc Ophthalmology Early multifocal electroretinography findings after intravitreal Conbercept in the treatment of wet age-related macular degeneration |
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RE1-994 Early multifocal electroretinography findings after intravitreal Conbercept in the treatment of wet age-related macular degeneration multifocal electroretinography conbercept wet age-related macular degeneration |
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Early multifocal electroretinography findings after intravitreal Conbercept in the treatment of wet age-related macular degeneration |
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Early multifocal electroretinography findings after intravitreal Conbercept in the treatment of wet age-related macular degeneration |
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Ding-Guo Huang |
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Guoji Yanke Zazhi |
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Ding-Guo Huang Jian-Long Zheng Guo-Qiao Lin Wei-Qi Chen |
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10.3980/j.issn.1672-5123.2018.9.31 |
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early multifocal electroretinography findings after intravitreal conbercept in the treatment of wet age-related macular degeneration |
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RE1-994 |
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Early multifocal electroretinography findings after intravitreal Conbercept in the treatment of wet age-related macular degeneration |
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AIM: To evaluate the early changes of retinal function in patients with wet age-related macular degeneration(ARMD)after intravitreal Conbercept treatment by multifocal electroretinography(mfERG). <p<METHODS: Wet ARMD patients diagnosed by fundus fluorescein angiography and received intravitreal injection of Conbercept(0.05mL/0.5mg)were included. Best corrected visual acuity(BCVA), incubation of N1, P1 and amplitude of P1 in mfERG test were recorded before and 1mo after treatment. <p<RESULTS: Twenty patients(20 eyes)were enrolled in total. The mean BCVA was 0.80±0.48 LogMAR at baseline and improved to 0.65±0.50 LogMAR after treatment(<i<P</i<<0.001). Mean P1 amplitude density of the mfERG Ring 1 increased from 39.59±16.60nV/deg<sup<2</sup< to 53.81±20.41nV/deg<sup<2</sup<(<i<P</i<=0.006). The change in visual acuity was positively correlated with the change in P1 amplitude density of Ring 1(<i<r</i<=-0.776, <i<P</i<<0.001). <p<CONCLUSION: Intravitreal conbercept injection can improve the central retinal function of wet ARMD patients in the short term. |
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AIM: To evaluate the early changes of retinal function in patients with wet age-related macular degeneration(ARMD)after intravitreal Conbercept treatment by multifocal electroretinography(mfERG). <p<METHODS: Wet ARMD patients diagnosed by fundus fluorescein angiography and received intravitreal injection of Conbercept(0.05mL/0.5mg)were included. Best corrected visual acuity(BCVA), incubation of N1, P1 and amplitude of P1 in mfERG test were recorded before and 1mo after treatment. <p<RESULTS: Twenty patients(20 eyes)were enrolled in total. The mean BCVA was 0.80±0.48 LogMAR at baseline and improved to 0.65±0.50 LogMAR after treatment(<i<P</i<<0.001). Mean P1 amplitude density of the mfERG Ring 1 increased from 39.59±16.60nV/deg<sup<2</sup< to 53.81±20.41nV/deg<sup<2</sup<(<i<P</i<=0.006). The change in visual acuity was positively correlated with the change in P1 amplitude density of Ring 1(<i<r</i<=-0.776, <i<P</i<<0.001). <p<CONCLUSION: Intravitreal conbercept injection can improve the central retinal function of wet ARMD patients in the short term. |
| abstract_unstemmed |
AIM: To evaluate the early changes of retinal function in patients with wet age-related macular degeneration(ARMD)after intravitreal Conbercept treatment by multifocal electroretinography(mfERG). <p<METHODS: Wet ARMD patients diagnosed by fundus fluorescein angiography and received intravitreal injection of Conbercept(0.05mL/0.5mg)were included. Best corrected visual acuity(BCVA), incubation of N1, P1 and amplitude of P1 in mfERG test were recorded before and 1mo after treatment. <p<RESULTS: Twenty patients(20 eyes)were enrolled in total. The mean BCVA was 0.80±0.48 LogMAR at baseline and improved to 0.65±0.50 LogMAR after treatment(<i<P</i<<0.001). Mean P1 amplitude density of the mfERG Ring 1 increased from 39.59±16.60nV/deg<sup<2</sup< to 53.81±20.41nV/deg<sup<2</sup<(<i<P</i<=0.006). The change in visual acuity was positively correlated with the change in P1 amplitude density of Ring 1(<i<r</i<=-0.776, <i<P</i<<0.001). <p<CONCLUSION: Intravitreal conbercept injection can improve the central retinal function of wet ARMD patients in the short term. |
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Early multifocal electroretinography findings after intravitreal Conbercept in the treatment of wet age-related macular degeneration |
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https://doi.org/10.3980/j.issn.1672-5123.2018.9.31 https://doaj.org/article/84c364a7cfe9494aa94eacc510e69478 http://ies.ijo.cn/cn_publish/2018/9/201809031.pdf https://doaj.org/toc/1672-5123 |
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