Diffuse large B-cell lymphoma of non-germinal center type of the buttock
Primary lymphoma of soft tissue is very rare. An 80-year-old man presented with a right buttock tumor measuring 5 × 5 × 4 cm. Tumorectomy was performed. The tumor was located in the fascia and subcutaneous tissue, and encapsulated by a thin capsule. Histologically, the tumor showed atypical lymphoid...
Ausführliche Beschreibung
Autor*in: |
Tadashi Terada, MD, PhD [verfasserIn] |
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Englisch |
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2016 |
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In: Human Pathology: Case Reports - Elsevier, 2016, 3(2016), C, Seite 27-29 |
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Übergeordnetes Werk: |
volume:3 ; year:2016 ; number:C ; pages:27-29 |
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DOI / URN: |
10.1016/j.ehpc.2014.11.006 |
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520 | |a Primary lymphoma of soft tissue is very rare. An 80-year-old man presented with a right buttock tumor measuring 5 × 5 × 4 cm. Tumorectomy was performed. The tumor was located in the fascia and subcutaneous tissue, and encapsulated by a thin capsule. Histologically, the tumor showed atypical lymphoid cell proliferation. Immunohistochemically, the tumor cells were positive for CD45, CD20, CD79a, and CD138. The Ki-67 labeling was 90%. In contrast, they were negative for pancytokeratins, epithelial membrane antigen, CD10, MUM1, bcl-6, cyclin D1, CD3, CD30, CD45RO, TdT, CD56, S100 protein, HMB45, chromogranin, α-smooth muscle actin, and desmin. A diagnosis of diffuse large B-cell lymphoma (DLBCL) of soft tissue was made. The subtype of DLBCL is non-germinal center type (non-GC). Systemic investigation using various imaging modalities including CT, MRI and Ga-scintigraphy revealed small nodular lesions up to 1 mm in the lungs and liver. However, biopsies of these locations were not performed because of his old age. The nodular lesions of the liver and lungs were small in diameter (up to 1 cm), and it is strongly likely that the buttock tumor is primary. The patient was treated by R-CHOP chemotherapy and radiation. He was referred to another specialized hospital for his will. | ||
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10.1016/j.ehpc.2014.11.006 doi (DE-627)DOAJ009787933 (DE-599)DOAJda3fdce027b549598b1b4bfcb31689a9 DE-627 ger DE-627 rakwb eng RB1-214 Tadashi Terada, MD, PhD verfasserin aut Diffuse large B-cell lymphoma of non-germinal center type of the buttock 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Primary lymphoma of soft tissue is very rare. An 80-year-old man presented with a right buttock tumor measuring 5 × 5 × 4 cm. Tumorectomy was performed. The tumor was located in the fascia and subcutaneous tissue, and encapsulated by a thin capsule. Histologically, the tumor showed atypical lymphoid cell proliferation. Immunohistochemically, the tumor cells were positive for CD45, CD20, CD79a, and CD138. The Ki-67 labeling was 90%. In contrast, they were negative for pancytokeratins, epithelial membrane antigen, CD10, MUM1, bcl-6, cyclin D1, CD3, CD30, CD45RO, TdT, CD56, S100 protein, HMB45, chromogranin, α-smooth muscle actin, and desmin. A diagnosis of diffuse large B-cell lymphoma (DLBCL) of soft tissue was made. The subtype of DLBCL is non-germinal center type (non-GC). Systemic investigation using various imaging modalities including CT, MRI and Ga-scintigraphy revealed small nodular lesions up to 1 mm in the lungs and liver. However, biopsies of these locations were not performed because of his old age. The nodular lesions of the liver and lungs were small in diameter (up to 1 cm), and it is strongly likely that the buttock tumor is primary. The patient was treated by R-CHOP chemotherapy and radiation. He was referred to another specialized hospital for his will. Lymphoma Soft tissue Histopathology Pathology In Human Pathology: Case Reports Elsevier, 2016 3(2016), C, Seite 27-29 (DE-627)835590143 (DE-600)2834872-2 22143300 nnns volume:3 year:2016 number:C pages:27-29 https://doi.org/10.1016/j.ehpc.2014.11.006 kostenfrei https://doaj.org/article/da3fdce027b549598b1b4bfcb31689a9 kostenfrei http://www.sciencedirect.com/science/article/pii/S221433001420071X kostenfrei https://doaj.org/toc/2214-3300 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 3 2016 C 27-29 |
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10.1016/j.ehpc.2014.11.006 doi (DE-627)DOAJ009787933 (DE-599)DOAJda3fdce027b549598b1b4bfcb31689a9 DE-627 ger DE-627 rakwb eng RB1-214 Tadashi Terada, MD, PhD verfasserin aut Diffuse large B-cell lymphoma of non-germinal center type of the buttock 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Primary lymphoma of soft tissue is very rare. An 80-year-old man presented with a right buttock tumor measuring 5 × 5 × 4 cm. Tumorectomy was performed. The tumor was located in the fascia and subcutaneous tissue, and encapsulated by a thin capsule. Histologically, the tumor showed atypical lymphoid cell proliferation. Immunohistochemically, the tumor cells were positive for CD45, CD20, CD79a, and CD138. The Ki-67 labeling was 90%. In contrast, they were negative for pancytokeratins, epithelial membrane antigen, CD10, MUM1, bcl-6, cyclin D1, CD3, CD30, CD45RO, TdT, CD56, S100 protein, HMB45, chromogranin, α-smooth muscle actin, and desmin. A diagnosis of diffuse large B-cell lymphoma (DLBCL) of soft tissue was made. The subtype of DLBCL is non-germinal center type (non-GC). Systemic investigation using various imaging modalities including CT, MRI and Ga-scintigraphy revealed small nodular lesions up to 1 mm in the lungs and liver. However, biopsies of these locations were not performed because of his old age. The nodular lesions of the liver and lungs were small in diameter (up to 1 cm), and it is strongly likely that the buttock tumor is primary. The patient was treated by R-CHOP chemotherapy and radiation. He was referred to another specialized hospital for his will. Lymphoma Soft tissue Histopathology Pathology In Human Pathology: Case Reports Elsevier, 2016 3(2016), C, Seite 27-29 (DE-627)835590143 (DE-600)2834872-2 22143300 nnns volume:3 year:2016 number:C pages:27-29 https://doi.org/10.1016/j.ehpc.2014.11.006 kostenfrei https://doaj.org/article/da3fdce027b549598b1b4bfcb31689a9 kostenfrei http://www.sciencedirect.com/science/article/pii/S221433001420071X kostenfrei https://doaj.org/toc/2214-3300 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 3 2016 C 27-29 |
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10.1016/j.ehpc.2014.11.006 doi (DE-627)DOAJ009787933 (DE-599)DOAJda3fdce027b549598b1b4bfcb31689a9 DE-627 ger DE-627 rakwb eng RB1-214 Tadashi Terada, MD, PhD verfasserin aut Diffuse large B-cell lymphoma of non-germinal center type of the buttock 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Primary lymphoma of soft tissue is very rare. An 80-year-old man presented with a right buttock tumor measuring 5 × 5 × 4 cm. Tumorectomy was performed. The tumor was located in the fascia and subcutaneous tissue, and encapsulated by a thin capsule. Histologically, the tumor showed atypical lymphoid cell proliferation. Immunohistochemically, the tumor cells were positive for CD45, CD20, CD79a, and CD138. The Ki-67 labeling was 90%. In contrast, they were negative for pancytokeratins, epithelial membrane antigen, CD10, MUM1, bcl-6, cyclin D1, CD3, CD30, CD45RO, TdT, CD56, S100 protein, HMB45, chromogranin, α-smooth muscle actin, and desmin. A diagnosis of diffuse large B-cell lymphoma (DLBCL) of soft tissue was made. The subtype of DLBCL is non-germinal center type (non-GC). Systemic investigation using various imaging modalities including CT, MRI and Ga-scintigraphy revealed small nodular lesions up to 1 mm in the lungs and liver. However, biopsies of these locations were not performed because of his old age. The nodular lesions of the liver and lungs were small in diameter (up to 1 cm), and it is strongly likely that the buttock tumor is primary. The patient was treated by R-CHOP chemotherapy and radiation. He was referred to another specialized hospital for his will. Lymphoma Soft tissue Histopathology Pathology In Human Pathology: Case Reports Elsevier, 2016 3(2016), C, Seite 27-29 (DE-627)835590143 (DE-600)2834872-2 22143300 nnns volume:3 year:2016 number:C pages:27-29 https://doi.org/10.1016/j.ehpc.2014.11.006 kostenfrei https://doaj.org/article/da3fdce027b549598b1b4bfcb31689a9 kostenfrei http://www.sciencedirect.com/science/article/pii/S221433001420071X kostenfrei https://doaj.org/toc/2214-3300 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 3 2016 C 27-29 |
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10.1016/j.ehpc.2014.11.006 doi (DE-627)DOAJ009787933 (DE-599)DOAJda3fdce027b549598b1b4bfcb31689a9 DE-627 ger DE-627 rakwb eng RB1-214 Tadashi Terada, MD, PhD verfasserin aut Diffuse large B-cell lymphoma of non-germinal center type of the buttock 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Primary lymphoma of soft tissue is very rare. An 80-year-old man presented with a right buttock tumor measuring 5 × 5 × 4 cm. Tumorectomy was performed. The tumor was located in the fascia and subcutaneous tissue, and encapsulated by a thin capsule. Histologically, the tumor showed atypical lymphoid cell proliferation. Immunohistochemically, the tumor cells were positive for CD45, CD20, CD79a, and CD138. The Ki-67 labeling was 90%. In contrast, they were negative for pancytokeratins, epithelial membrane antigen, CD10, MUM1, bcl-6, cyclin D1, CD3, CD30, CD45RO, TdT, CD56, S100 protein, HMB45, chromogranin, α-smooth muscle actin, and desmin. A diagnosis of diffuse large B-cell lymphoma (DLBCL) of soft tissue was made. The subtype of DLBCL is non-germinal center type (non-GC). Systemic investigation using various imaging modalities including CT, MRI and Ga-scintigraphy revealed small nodular lesions up to 1 mm in the lungs and liver. However, biopsies of these locations were not performed because of his old age. The nodular lesions of the liver and lungs were small in diameter (up to 1 cm), and it is strongly likely that the buttock tumor is primary. The patient was treated by R-CHOP chemotherapy and radiation. He was referred to another specialized hospital for his will. Lymphoma Soft tissue Histopathology Pathology In Human Pathology: Case Reports Elsevier, 2016 3(2016), C, Seite 27-29 (DE-627)835590143 (DE-600)2834872-2 22143300 nnns volume:3 year:2016 number:C pages:27-29 https://doi.org/10.1016/j.ehpc.2014.11.006 kostenfrei https://doaj.org/article/da3fdce027b549598b1b4bfcb31689a9 kostenfrei http://www.sciencedirect.com/science/article/pii/S221433001420071X kostenfrei https://doaj.org/toc/2214-3300 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 3 2016 C 27-29 |
allfieldsSound |
10.1016/j.ehpc.2014.11.006 doi (DE-627)DOAJ009787933 (DE-599)DOAJda3fdce027b549598b1b4bfcb31689a9 DE-627 ger DE-627 rakwb eng RB1-214 Tadashi Terada, MD, PhD verfasserin aut Diffuse large B-cell lymphoma of non-germinal center type of the buttock 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Primary lymphoma of soft tissue is very rare. An 80-year-old man presented with a right buttock tumor measuring 5 × 5 × 4 cm. Tumorectomy was performed. The tumor was located in the fascia and subcutaneous tissue, and encapsulated by a thin capsule. Histologically, the tumor showed atypical lymphoid cell proliferation. Immunohistochemically, the tumor cells were positive for CD45, CD20, CD79a, and CD138. The Ki-67 labeling was 90%. In contrast, they were negative for pancytokeratins, epithelial membrane antigen, CD10, MUM1, bcl-6, cyclin D1, CD3, CD30, CD45RO, TdT, CD56, S100 protein, HMB45, chromogranin, α-smooth muscle actin, and desmin. A diagnosis of diffuse large B-cell lymphoma (DLBCL) of soft tissue was made. The subtype of DLBCL is non-germinal center type (non-GC). Systemic investigation using various imaging modalities including CT, MRI and Ga-scintigraphy revealed small nodular lesions up to 1 mm in the lungs and liver. However, biopsies of these locations were not performed because of his old age. The nodular lesions of the liver and lungs were small in diameter (up to 1 cm), and it is strongly likely that the buttock tumor is primary. The patient was treated by R-CHOP chemotherapy and radiation. He was referred to another specialized hospital for his will. Lymphoma Soft tissue Histopathology Pathology In Human Pathology: Case Reports Elsevier, 2016 3(2016), C, Seite 27-29 (DE-627)835590143 (DE-600)2834872-2 22143300 nnns volume:3 year:2016 number:C pages:27-29 https://doi.org/10.1016/j.ehpc.2014.11.006 kostenfrei https://doaj.org/article/da3fdce027b549598b1b4bfcb31689a9 kostenfrei http://www.sciencedirect.com/science/article/pii/S221433001420071X kostenfrei https://doaj.org/toc/2214-3300 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 3 2016 C 27-29 |
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Primary lymphoma of soft tissue is very rare. An 80-year-old man presented with a right buttock tumor measuring 5 × 5 × 4 cm. Tumorectomy was performed. The tumor was located in the fascia and subcutaneous tissue, and encapsulated by a thin capsule. Histologically, the tumor showed atypical lymphoid cell proliferation. Immunohistochemically, the tumor cells were positive for CD45, CD20, CD79a, and CD138. The Ki-67 labeling was 90%. In contrast, they were negative for pancytokeratins, epithelial membrane antigen, CD10, MUM1, bcl-6, cyclin D1, CD3, CD30, CD45RO, TdT, CD56, S100 protein, HMB45, chromogranin, α-smooth muscle actin, and desmin. A diagnosis of diffuse large B-cell lymphoma (DLBCL) of soft tissue was made. The subtype of DLBCL is non-germinal center type (non-GC). Systemic investigation using various imaging modalities including CT, MRI and Ga-scintigraphy revealed small nodular lesions up to 1 mm in the lungs and liver. However, biopsies of these locations were not performed because of his old age. The nodular lesions of the liver and lungs were small in diameter (up to 1 cm), and it is strongly likely that the buttock tumor is primary. The patient was treated by R-CHOP chemotherapy and radiation. He was referred to another specialized hospital for his will. |
abstractGer |
Primary lymphoma of soft tissue is very rare. An 80-year-old man presented with a right buttock tumor measuring 5 × 5 × 4 cm. Tumorectomy was performed. The tumor was located in the fascia and subcutaneous tissue, and encapsulated by a thin capsule. Histologically, the tumor showed atypical lymphoid cell proliferation. Immunohistochemically, the tumor cells were positive for CD45, CD20, CD79a, and CD138. The Ki-67 labeling was 90%. In contrast, they were negative for pancytokeratins, epithelial membrane antigen, CD10, MUM1, bcl-6, cyclin D1, CD3, CD30, CD45RO, TdT, CD56, S100 protein, HMB45, chromogranin, α-smooth muscle actin, and desmin. A diagnosis of diffuse large B-cell lymphoma (DLBCL) of soft tissue was made. The subtype of DLBCL is non-germinal center type (non-GC). Systemic investigation using various imaging modalities including CT, MRI and Ga-scintigraphy revealed small nodular lesions up to 1 mm in the lungs and liver. However, biopsies of these locations were not performed because of his old age. The nodular lesions of the liver and lungs were small in diameter (up to 1 cm), and it is strongly likely that the buttock tumor is primary. The patient was treated by R-CHOP chemotherapy and radiation. He was referred to another specialized hospital for his will. |
abstract_unstemmed |
Primary lymphoma of soft tissue is very rare. An 80-year-old man presented with a right buttock tumor measuring 5 × 5 × 4 cm. Tumorectomy was performed. The tumor was located in the fascia and subcutaneous tissue, and encapsulated by a thin capsule. Histologically, the tumor showed atypical lymphoid cell proliferation. Immunohistochemically, the tumor cells were positive for CD45, CD20, CD79a, and CD138. The Ki-67 labeling was 90%. In contrast, they were negative for pancytokeratins, epithelial membrane antigen, CD10, MUM1, bcl-6, cyclin D1, CD3, CD30, CD45RO, TdT, CD56, S100 protein, HMB45, chromogranin, α-smooth muscle actin, and desmin. A diagnosis of diffuse large B-cell lymphoma (DLBCL) of soft tissue was made. The subtype of DLBCL is non-germinal center type (non-GC). Systemic investigation using various imaging modalities including CT, MRI and Ga-scintigraphy revealed small nodular lesions up to 1 mm in the lungs and liver. However, biopsies of these locations were not performed because of his old age. The nodular lesions of the liver and lungs were small in diameter (up to 1 cm), and it is strongly likely that the buttock tumor is primary. The patient was treated by R-CHOP chemotherapy and radiation. He was referred to another specialized hospital for his will. |
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