Phenolic Plant Extracts Versus Penicillin G: In Vitro Susceptibility of <em<Staphylococcus aureus</em< Isolated from Bovine Mastitis

Antibiotics are the elective drugs in bovine mastitis (BM) treatment, despite their low rates of efficiency and effectiveness and increasing risk of pathogen resistance. In this sense, it is urgent to discover new and effective antimicrobial agents to apply in BM control and even treatment. Plant ex...
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Gespeichert in:

Autor*in:	Fernanda Gomes [verfasserIn] Maria Elisa Rodrigues [verfasserIn] Natália Martins [verfasserIn] Isabel C.F.R. Ferreira [verfasserIn] Mariana Henriques [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Schlagwörter:	bovine mastitis penicillin G

Übergeordnetes Werk:	In: Pharmaceuticals - MDPI AG, 2005, 12(2019), 3, p 128
Übergeordnetes Werk:	volume:12 ; year:2019 ; number:3, p 128

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/ph12030128

Katalog-ID:	DOAJ010355022

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520			\|a Antibiotics are the elective drugs in bovine mastitis (BM) treatment, despite their low rates of efficiency and effectiveness and increasing risk of pathogen resistance. In this sense, it is urgent to discover new and effective antimicrobial agents to apply in BM control and even treatment. Plant extracts have been widely recognized as a rich source of phytochemicals with antimicrobial potential. Thus, the present work aims to compare the bioactivity of <i<Eucalyptus globulus</i< and <i<Juglans regia</i< extracts against <i<Staphylococcus aureus</i< bovine mastitis strains with penicillin G. At non-toxic concentrations, <i<E. globulus</i< exerted a bacteriostatic effect in planktonic cells and <i<J. regia</i< had no antimicrobial activity. Penicillin G, at minimum inhibitory concentration (MIC), demonstrated bactericidal activity, but just for <i<S. aureus</i< 3, 5, 6 and ATCC 25923, while the other strains seem to have acquired resistance. On the other hand, <i<E. globulus</i< and penicillin G in combination demonstrated synergy, being the most effective approach against <i<S. aureus</i< 1, 2 and 4. Thus, penicillin alone and in combination with <i<E. globulus</i< or <i<J. regia</i< seems to be promissory strategies to control bovine mastitis infections.
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allfields	10.3390/ph12030128 doi (DE-627)DOAJ010355022 (DE-599)DOAJ833c9f10256a408f97f4fce16929cee9 DE-627 ger DE-627 rakwb eng RS1-441 Fernanda Gomes verfasserin aut Phenolic Plant Extracts Versus Penicillin G: In Vitro Susceptibility of <em<Staphylococcus aureus</em< Isolated from Bovine Mastitis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Antibiotics are the elective drugs in bovine mastitis (BM) treatment, despite their low rates of efficiency and effectiveness and increasing risk of pathogen resistance. In this sense, it is urgent to discover new and effective antimicrobial agents to apply in BM control and even treatment. Plant extracts have been widely recognized as a rich source of phytochemicals with antimicrobial potential. Thus, the present work aims to compare the bioactivity of <i<Eucalyptus globulus</i< and <i<Juglans regia</i< extracts against <i<Staphylococcus aureus</i< bovine mastitis strains with penicillin G. At non-toxic concentrations, <i<E. globulus</i< exerted a bacteriostatic effect in planktonic cells and <i<J. regia</i< had no antimicrobial activity. Penicillin G, at minimum inhibitory concentration (MIC), demonstrated bactericidal activity, but just for <i<S. aureus</i< 3, 5, 6 and ATCC 25923, while the other strains seem to have acquired resistance. On the other hand, <i<E. globulus</i< and penicillin G in combination demonstrated synergy, being the most effective approach against <i<S. aureus</i< 1, 2 and 4. Thus, penicillin alone and in combination with <i<E. globulus</i< or <i<J. regia</i< seems to be promissory strategies to control bovine mastitis infections. bovine mastitis <i<Eucalyptus globulus</i< Labill. <i<Juglans regia</i< L. penicillin G <i<Staphylococcus aureus</i< Medicine R Pharmacy and materia medica Maria Elisa Rodrigues verfasserin aut Natália Martins verfasserin aut Isabel C.F.R. Ferreira verfasserin aut Mariana Henriques verfasserin aut In Pharmaceuticals MDPI AG, 2005 12(2019), 3, p 128 (DE-627)491437528 (DE-600)2193542-7 14248247 nnns volume:12 year:2019 number:3, p 128 https://doi.org/10.3390/ph12030128 kostenfrei https://doaj.org/article/833c9f10256a408f97f4fce16929cee9 kostenfrei https://www.mdpi.com/1424-8247/12/3/128 kostenfrei https://doaj.org/toc/1424-8247 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2019 3, p 128
spelling	10.3390/ph12030128 doi (DE-627)DOAJ010355022 (DE-599)DOAJ833c9f10256a408f97f4fce16929cee9 DE-627 ger DE-627 rakwb eng RS1-441 Fernanda Gomes verfasserin aut Phenolic Plant Extracts Versus Penicillin G: In Vitro Susceptibility of <em<Staphylococcus aureus</em< Isolated from Bovine Mastitis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Antibiotics are the elective drugs in bovine mastitis (BM) treatment, despite their low rates of efficiency and effectiveness and increasing risk of pathogen resistance. In this sense, it is urgent to discover new and effective antimicrobial agents to apply in BM control and even treatment. Plant extracts have been widely recognized as a rich source of phytochemicals with antimicrobial potential. Thus, the present work aims to compare the bioactivity of <i<Eucalyptus globulus</i< and <i<Juglans regia</i< extracts against <i<Staphylococcus aureus</i< bovine mastitis strains with penicillin G. At non-toxic concentrations, <i<E. globulus</i< exerted a bacteriostatic effect in planktonic cells and <i<J. regia</i< had no antimicrobial activity. Penicillin G, at minimum inhibitory concentration (MIC), demonstrated bactericidal activity, but just for <i<S. aureus</i< 3, 5, 6 and ATCC 25923, while the other strains seem to have acquired resistance. On the other hand, <i<E. globulus</i< and penicillin G in combination demonstrated synergy, being the most effective approach against <i<S. aureus</i< 1, 2 and 4. Thus, penicillin alone and in combination with <i<E. globulus</i< or <i<J. regia</i< seems to be promissory strategies to control bovine mastitis infections. bovine mastitis <i<Eucalyptus globulus</i< Labill. <i<Juglans regia</i< L. penicillin G <i<Staphylococcus aureus</i< Medicine R Pharmacy and materia medica Maria Elisa Rodrigues verfasserin aut Natália Martins verfasserin aut Isabel C.F.R. Ferreira verfasserin aut Mariana Henriques verfasserin aut In Pharmaceuticals MDPI AG, 2005 12(2019), 3, p 128 (DE-627)491437528 (DE-600)2193542-7 14248247 nnns volume:12 year:2019 number:3, p 128 https://doi.org/10.3390/ph12030128 kostenfrei https://doaj.org/article/833c9f10256a408f97f4fce16929cee9 kostenfrei https://www.mdpi.com/1424-8247/12/3/128 kostenfrei https://doaj.org/toc/1424-8247 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2019 3, p 128
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allfieldsSound	10.3390/ph12030128 doi (DE-627)DOAJ010355022 (DE-599)DOAJ833c9f10256a408f97f4fce16929cee9 DE-627 ger DE-627 rakwb eng RS1-441 Fernanda Gomes verfasserin aut Phenolic Plant Extracts Versus Penicillin G: In Vitro Susceptibility of <em<Staphylococcus aureus</em< Isolated from Bovine Mastitis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Antibiotics are the elective drugs in bovine mastitis (BM) treatment, despite their low rates of efficiency and effectiveness and increasing risk of pathogen resistance. In this sense, it is urgent to discover new and effective antimicrobial agents to apply in BM control and even treatment. Plant extracts have been widely recognized as a rich source of phytochemicals with antimicrobial potential. Thus, the present work aims to compare the bioactivity of <i<Eucalyptus globulus</i< and <i<Juglans regia</i< extracts against <i<Staphylococcus aureus</i< bovine mastitis strains with penicillin G. At non-toxic concentrations, <i<E. globulus</i< exerted a bacteriostatic effect in planktonic cells and <i<J. regia</i< had no antimicrobial activity. Penicillin G, at minimum inhibitory concentration (MIC), demonstrated bactericidal activity, but just for <i<S. aureus</i< 3, 5, 6 and ATCC 25923, while the other strains seem to have acquired resistance. On the other hand, <i<E. globulus</i< and penicillin G in combination demonstrated synergy, being the most effective approach against <i<S. aureus</i< 1, 2 and 4. Thus, penicillin alone and in combination with <i<E. globulus</i< or <i<J. regia</i< seems to be promissory strategies to control bovine mastitis infections. bovine mastitis <i<Eucalyptus globulus</i< Labill. <i<Juglans regia</i< L. penicillin G <i<Staphylococcus aureus</i< Medicine R Pharmacy and materia medica Maria Elisa Rodrigues verfasserin aut Natália Martins verfasserin aut Isabel C.F.R. Ferreira verfasserin aut Mariana Henriques verfasserin aut In Pharmaceuticals MDPI AG, 2005 12(2019), 3, p 128 (DE-627)491437528 (DE-600)2193542-7 14248247 nnns volume:12 year:2019 number:3, p 128 https://doi.org/10.3390/ph12030128 kostenfrei https://doaj.org/article/833c9f10256a408f97f4fce16929cee9 kostenfrei https://www.mdpi.com/1424-8247/12/3/128 kostenfrei https://doaj.org/toc/1424-8247 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2019 3, p 128
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topic_facet	bovine mastitis <i<Eucalyptus globulus</i< Labill. <i<Juglans regia</i< L. penicillin G <i<Staphylococcus aureus</i< Medicine R Pharmacy and materia medica
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authorswithroles_txt_mv	Fernanda Gomes @@aut@@ Maria Elisa Rodrigues @@aut@@ Natália Martins @@aut@@ Isabel C.F.R. Ferreira @@aut@@ Mariana Henriques @@aut@@
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callnumber-first	R - Medicine
author	Fernanda Gomes
spellingShingle	Fernanda Gomes misc RS1-441 misc bovine mastitis misc <i<Eucalyptus globulus</i< Labill. misc <i<Juglans regia</i< L. misc penicillin G misc <i<Staphylococcus aureus</i< misc Medicine misc R misc Pharmacy and materia medica Phenolic Plant Extracts Versus Penicillin G: In Vitro Susceptibility of <em<Staphylococcus aureus</em< Isolated from Bovine Mastitis
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topic_title	RS1-441 Phenolic Plant Extracts Versus Penicillin G: In Vitro Susceptibility of <em<Staphylococcus aureus</em< Isolated from Bovine Mastitis bovine mastitis <i<Eucalyptus globulus</i< Labill <i<Juglans regia</i< L. penicillin G <i<Staphylococcus aureus</i<
topic	misc RS1-441 misc bovine mastitis misc <i<Eucalyptus globulus</i< Labill. misc <i<Juglans regia</i< L. misc penicillin G misc <i<Staphylococcus aureus</i< misc Medicine misc R misc Pharmacy and materia medica
topic_unstemmed	misc RS1-441 misc bovine mastitis misc <i<Eucalyptus globulus</i< Labill. misc <i<Juglans regia</i< L. misc penicillin G misc <i<Staphylococcus aureus</i< misc Medicine misc R misc Pharmacy and materia medica
topic_browse	misc RS1-441 misc bovine mastitis misc <i<Eucalyptus globulus</i< Labill. misc <i<Juglans regia</i< L. misc penicillin G misc <i<Staphylococcus aureus</i< misc Medicine misc R misc Pharmacy and materia medica
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title	Phenolic Plant Extracts Versus Penicillin G: In Vitro Susceptibility of <em<Staphylococcus aureus</em< Isolated from Bovine Mastitis
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title_full	Phenolic Plant Extracts Versus Penicillin G: In Vitro Susceptibility of <em<Staphylococcus aureus</em< Isolated from Bovine Mastitis
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author_browse	Fernanda Gomes Maria Elisa Rodrigues Natália Martins Isabel C.F.R. Ferreira Mariana Henriques
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title_sort	phenolic plant extracts versus penicillin g: in vitro susceptibility of <em<staphylococcus aureus</em< isolated from bovine mastitis
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title_auth	Phenolic Plant Extracts Versus Penicillin G: In Vitro Susceptibility of <em<Staphylococcus aureus</em< Isolated from Bovine Mastitis
abstract	Antibiotics are the elective drugs in bovine mastitis (BM) treatment, despite their low rates of efficiency and effectiveness and increasing risk of pathogen resistance. In this sense, it is urgent to discover new and effective antimicrobial agents to apply in BM control and even treatment. Plant extracts have been widely recognized as a rich source of phytochemicals with antimicrobial potential. Thus, the present work aims to compare the bioactivity of <i<Eucalyptus globulus</i< and <i<Juglans regia</i< extracts against <i<Staphylococcus aureus</i< bovine mastitis strains with penicillin G. At non-toxic concentrations, <i<E. globulus</i< exerted a bacteriostatic effect in planktonic cells and <i<J. regia</i< had no antimicrobial activity. Penicillin G, at minimum inhibitory concentration (MIC), demonstrated bactericidal activity, but just for <i<S. aureus</i< 3, 5, 6 and ATCC 25923, while the other strains seem to have acquired resistance. On the other hand, <i<E. globulus</i< and penicillin G in combination demonstrated synergy, being the most effective approach against <i<S. aureus</i< 1, 2 and 4. Thus, penicillin alone and in combination with <i<E. globulus</i< or <i<J. regia</i< seems to be promissory strategies to control bovine mastitis infections.
abstractGer	Antibiotics are the elective drugs in bovine mastitis (BM) treatment, despite their low rates of efficiency and effectiveness and increasing risk of pathogen resistance. In this sense, it is urgent to discover new and effective antimicrobial agents to apply in BM control and even treatment. Plant extracts have been widely recognized as a rich source of phytochemicals with antimicrobial potential. Thus, the present work aims to compare the bioactivity of <i<Eucalyptus globulus</i< and <i<Juglans regia</i< extracts against <i<Staphylococcus aureus</i< bovine mastitis strains with penicillin G. At non-toxic concentrations, <i<E. globulus</i< exerted a bacteriostatic effect in planktonic cells and <i<J. regia</i< had no antimicrobial activity. Penicillin G, at minimum inhibitory concentration (MIC), demonstrated bactericidal activity, but just for <i<S. aureus</i< 3, 5, 6 and ATCC 25923, while the other strains seem to have acquired resistance. On the other hand, <i<E. globulus</i< and penicillin G in combination demonstrated synergy, being the most effective approach against <i<S. aureus</i< 1, 2 and 4. Thus, penicillin alone and in combination with <i<E. globulus</i< or <i<J. regia</i< seems to be promissory strategies to control bovine mastitis infections.
abstract_unstemmed	Antibiotics are the elective drugs in bovine mastitis (BM) treatment, despite their low rates of efficiency and effectiveness and increasing risk of pathogen resistance. In this sense, it is urgent to discover new and effective antimicrobial agents to apply in BM control and even treatment. Plant extracts have been widely recognized as a rich source of phytochemicals with antimicrobial potential. Thus, the present work aims to compare the bioactivity of <i<Eucalyptus globulus</i< and <i<Juglans regia</i< extracts against <i<Staphylococcus aureus</i< bovine mastitis strains with penicillin G. At non-toxic concentrations, <i<E. globulus</i< exerted a bacteriostatic effect in planktonic cells and <i<J. regia</i< had no antimicrobial activity. Penicillin G, at minimum inhibitory concentration (MIC), demonstrated bactericidal activity, but just for <i<S. aureus</i< 3, 5, 6 and ATCC 25923, while the other strains seem to have acquired resistance. On the other hand, <i<E. globulus</i< and penicillin G in combination demonstrated synergy, being the most effective approach against <i<S. aureus</i< 1, 2 and 4. Thus, penicillin alone and in combination with <i<E. globulus</i< or <i<J. regia</i< seems to be promissory strategies to control bovine mastitis infections.
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title_short	Phenolic Plant Extracts Versus Penicillin G: In Vitro Susceptibility of <em<Staphylococcus aureus</em< Isolated from Bovine Mastitis
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In this sense, it is urgent to discover new and effective antimicrobial agents to apply in BM control and even treatment. Plant extracts have been widely recognized as a rich source of phytochemicals with antimicrobial potential. Thus, the present work aims to compare the bioactivity of <i<Eucalyptus globulus</i< and <i<Juglans regia</i< extracts against <i<Staphylococcus aureus</i< bovine mastitis strains with penicillin G. At non-toxic concentrations, <i<E. globulus</i< exerted a bacteriostatic effect in planktonic cells and <i<J. regia</i< had no antimicrobial activity. Penicillin G, at minimum inhibitory concentration (MIC), demonstrated bactericidal activity, but just for <i<S. aureus</i< 3, 5, 6 and ATCC 25923, while the other strains seem to have acquired resistance. On the other hand, <i<E. globulus</i< and penicillin G in combination demonstrated synergy, being the most effective approach against <i<S. aureus</i< 1, 2 and 4. 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Phenolic Plant Extracts Versus Penicillin G: In Vitro Susceptibility of <em<Staphylococcus aureus</em< Isolated from Bovine Mastitis

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