Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India

Context: Recent advances in neonatology have influenced the incidence and severity of ROP in a dichotomous fashion. Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthwei...
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Autor*in:	Krishna A Rao [verfasserIn] Jayashree Purkayastha [verfasserIn] Manali Hazarika [verfasserIn] Raghuvamsi Chaitra [verfasserIn] K Mithun Adith [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2013

Schlagwörter:	Anterior segment parameter pars plana vitrectomy pentacam silicone oil injection Astigmatism cataract surgery toric lens toric intraocular lens Amblyopia anisometropia occlusion recurrence visual acuity Cortical visual impairment flash visual evoked potentials periventricular leucomalacia stimulation frequency in visual evoked potentials visual evoked potentials Cytomegalovirus retinitis cytomegalovirus retinitis retinal detachment cytomegalovirus highly active antiretroviral therapy Incidence postnatal weight gain retinopathy of prematurity risk factors weight gain proportion

Übergeordnetes Werk:	In: Indian Journal of Ophthalmology - Wolters Kluwer Medknow Publications, 2005, 61(2013), 11, Seite 640-644
Übergeordnetes Werk:	volume:61 ; year:2013 ; number:11 ; pages:640-644

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.4103/0301-4738.119347

Katalog-ID:	DOAJ010749896

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245	1	0	\|a Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India
264		1	\|c 2013
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520			\|a Context: Recent advances in neonatology have influenced the incidence and severity of ROP in a dichotomous fashion. Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthweight < 1500g and/or gestational age ≤ 32 weeks and also those with gestational age < 32 weeks, with birthweight between 1500-2000 g, who were at risk for ROP were selected. Weight gain proportion was measured as weight at 6 weeks minus birthweight divided by birthweight. Statistical Analysis: Univariate and multivariate logistic regression. Results: Incidence of any ROP was 21.6% while severe ROP was 6.7%. Prenatal factors like multiple gestation (P = 0.510) and antenatal steroids (P = 0.104) were not significantly associated with ROP. On multivariate analysis, postnatal factors like weight at birth < 1250 g (P = 0.01) and gestational age between 31-32 weeks (P = 0.02) were independent risk factors for any ROP, while intraventricular hemorrhage (P = 0.03) was the only independent risk factor for severe ROP. Mean birthweight of infants with severe ROP was 1056 μ 207 g (P = 0.004), which was significantly low. After logistic regression, the mean weight gain proportion at 6 weeks, of those neonates with severe ROP was 30%. Conclusions: Low birthweight and prematurity were the most important risk factors for developing any ROP, while intraventricular hemorrhage was the independent risk factor for developing severe ROP. The mean postnatal weight gain at 6 weeks was not statistically significant in neonates with severe ROP.
650		4	\|a Anterior segment parameter
650		4	\|a pars plana vitrectomy
650		4	\|a pentacam
650		4	\|a silicone oil injection
650		4	\|a Astigmatism
650		4	\|a cataract surgery
650		4	\|a toric lens
650		4	\|a toric intraocular lens
650		4	\|a Amblyopia
650		4	\|a anisometropia
650		4	\|a occlusion
650		4	\|a recurrence
650		4	\|a visual acuity
650		4	\|a Cortical visual impairment
650		4	\|a flash visual evoked potentials
650		4	\|a periventricular leucomalacia
650		4	\|a stimulation frequency in visual evoked potentials
650		4	\|a visual evoked potentials
650		4	\|a Cytomegalovirus retinitis
650		4	\|a cytomegalovirus retinitis retinal detachment
650		4	\|a cytomegalovirus
650		4	\|a highly active antiretroviral therapy
650		4	\|a Incidence
650		4	\|a postnatal weight gain
650		4	\|a retinopathy of prematurity
650		4	\|a risk factors
650		4	\|a weight gain proportion
653		0	\|a Ophthalmology
700	0		\|a Jayashree Purkayastha \|e verfasserin \|4 aut
700	0		\|a Manali Hazarika \|e verfasserin \|4 aut
700	0		\|a Raghuvamsi Chaitra \|e verfasserin \|4 aut
700	0		\|a K Mithun Adith \|e verfasserin \|4 aut
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allfields	10.4103/0301-4738.119347 doi (DE-627)DOAJ010749896 (DE-599)DOAJeb584feafb6345818c6a8b36d96dbd8a DE-627 ger DE-627 rakwb eng RE1-994 Krishna A Rao verfasserin aut Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Context: Recent advances in neonatology have influenced the incidence and severity of ROP in a dichotomous fashion. Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthweight < 1500g and/or gestational age ≤ 32 weeks and also those with gestational age < 32 weeks, with birthweight between 1500-2000 g, who were at risk for ROP were selected. Weight gain proportion was measured as weight at 6 weeks minus birthweight divided by birthweight. Statistical Analysis: Univariate and multivariate logistic regression. Results: Incidence of any ROP was 21.6% while severe ROP was 6.7%. Prenatal factors like multiple gestation (P = 0.510) and antenatal steroids (P = 0.104) were not significantly associated with ROP. On multivariate analysis, postnatal factors like weight at birth < 1250 g (P = 0.01) and gestational age between 31-32 weeks (P = 0.02) were independent risk factors for any ROP, while intraventricular hemorrhage (P = 0.03) was the only independent risk factor for severe ROP. Mean birthweight of infants with severe ROP was 1056 μ 207 g (P = 0.004), which was significantly low. After logistic regression, the mean weight gain proportion at 6 weeks, of those neonates with severe ROP was 30%. Conclusions: Low birthweight and prematurity were the most important risk factors for developing any ROP, while intraventricular hemorrhage was the independent risk factor for developing severe ROP. The mean postnatal weight gain at 6 weeks was not statistically significant in neonates with severe ROP. Anterior segment parameter pars plana vitrectomy pentacam silicone oil injection Astigmatism cataract surgery toric lens toric intraocular lens Amblyopia anisometropia occlusion recurrence visual acuity Cortical visual impairment flash visual evoked potentials periventricular leucomalacia stimulation frequency in visual evoked potentials visual evoked potentials Cytomegalovirus retinitis cytomegalovirus retinitis retinal detachment cytomegalovirus highly active antiretroviral therapy Incidence postnatal weight gain retinopathy of prematurity risk factors weight gain proportion Ophthalmology Jayashree Purkayastha verfasserin aut Manali Hazarika verfasserin aut Raghuvamsi Chaitra verfasserin aut K Mithun Adith verfasserin aut In Indian Journal of Ophthalmology Wolters Kluwer Medknow Publications, 2005 61(2013), 11, Seite 640-644 (DE-627)485243563 (DE-600)2185999-1 19983689 nnns volume:61 year:2013 number:11 pages:640-644 https://doi.org/10.4103/0301-4738.119347 kostenfrei https://doaj.org/article/eb584feafb6345818c6a8b36d96dbd8a kostenfrei http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=11;spage=640;epage=644;aulast=Rao kostenfrei https://doaj.org/toc/0301-4738 Journal toc kostenfrei https://doaj.org/toc/1998-3689 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 61 2013 11 640-644
spelling	10.4103/0301-4738.119347 doi (DE-627)DOAJ010749896 (DE-599)DOAJeb584feafb6345818c6a8b36d96dbd8a DE-627 ger DE-627 rakwb eng RE1-994 Krishna A Rao verfasserin aut Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Context: Recent advances in neonatology have influenced the incidence and severity of ROP in a dichotomous fashion. Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthweight < 1500g and/or gestational age ≤ 32 weeks and also those with gestational age < 32 weeks, with birthweight between 1500-2000 g, who were at risk for ROP were selected. Weight gain proportion was measured as weight at 6 weeks minus birthweight divided by birthweight. Statistical Analysis: Univariate and multivariate logistic regression. Results: Incidence of any ROP was 21.6% while severe ROP was 6.7%. Prenatal factors like multiple gestation (P = 0.510) and antenatal steroids (P = 0.104) were not significantly associated with ROP. On multivariate analysis, postnatal factors like weight at birth < 1250 g (P = 0.01) and gestational age between 31-32 weeks (P = 0.02) were independent risk factors for any ROP, while intraventricular hemorrhage (P = 0.03) was the only independent risk factor for severe ROP. Mean birthweight of infants with severe ROP was 1056 μ 207 g (P = 0.004), which was significantly low. After logistic regression, the mean weight gain proportion at 6 weeks, of those neonates with severe ROP was 30%. Conclusions: Low birthweight and prematurity were the most important risk factors for developing any ROP, while intraventricular hemorrhage was the independent risk factor for developing severe ROP. The mean postnatal weight gain at 6 weeks was not statistically significant in neonates with severe ROP. Anterior segment parameter pars plana vitrectomy pentacam silicone oil injection Astigmatism cataract surgery toric lens toric intraocular lens Amblyopia anisometropia occlusion recurrence visual acuity Cortical visual impairment flash visual evoked potentials periventricular leucomalacia stimulation frequency in visual evoked potentials visual evoked potentials Cytomegalovirus retinitis cytomegalovirus retinitis retinal detachment cytomegalovirus highly active antiretroviral therapy Incidence postnatal weight gain retinopathy of prematurity risk factors weight gain proportion Ophthalmology Jayashree Purkayastha verfasserin aut Manali Hazarika verfasserin aut Raghuvamsi Chaitra verfasserin aut K Mithun Adith verfasserin aut In Indian Journal of Ophthalmology Wolters Kluwer Medknow Publications, 2005 61(2013), 11, Seite 640-644 (DE-627)485243563 (DE-600)2185999-1 19983689 nnns volume:61 year:2013 number:11 pages:640-644 https://doi.org/10.4103/0301-4738.119347 kostenfrei https://doaj.org/article/eb584feafb6345818c6a8b36d96dbd8a kostenfrei http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=11;spage=640;epage=644;aulast=Rao kostenfrei https://doaj.org/toc/0301-4738 Journal toc kostenfrei https://doaj.org/toc/1998-3689 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 61 2013 11 640-644
allfields_unstemmed	10.4103/0301-4738.119347 doi (DE-627)DOAJ010749896 (DE-599)DOAJeb584feafb6345818c6a8b36d96dbd8a DE-627 ger DE-627 rakwb eng RE1-994 Krishna A Rao verfasserin aut Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Context: Recent advances in neonatology have influenced the incidence and severity of ROP in a dichotomous fashion. Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthweight < 1500g and/or gestational age ≤ 32 weeks and also those with gestational age < 32 weeks, with birthweight between 1500-2000 g, who were at risk for ROP were selected. Weight gain proportion was measured as weight at 6 weeks minus birthweight divided by birthweight. Statistical Analysis: Univariate and multivariate logistic regression. Results: Incidence of any ROP was 21.6% while severe ROP was 6.7%. Prenatal factors like multiple gestation (P = 0.510) and antenatal steroids (P = 0.104) were not significantly associated with ROP. On multivariate analysis, postnatal factors like weight at birth < 1250 g (P = 0.01) and gestational age between 31-32 weeks (P = 0.02) were independent risk factors for any ROP, while intraventricular hemorrhage (P = 0.03) was the only independent risk factor for severe ROP. Mean birthweight of infants with severe ROP was 1056 μ 207 g (P = 0.004), which was significantly low. After logistic regression, the mean weight gain proportion at 6 weeks, of those neonates with severe ROP was 30%. Conclusions: Low birthweight and prematurity were the most important risk factors for developing any ROP, while intraventricular hemorrhage was the independent risk factor for developing severe ROP. The mean postnatal weight gain at 6 weeks was not statistically significant in neonates with severe ROP. Anterior segment parameter pars plana vitrectomy pentacam silicone oil injection Astigmatism cataract surgery toric lens toric intraocular lens Amblyopia anisometropia occlusion recurrence visual acuity Cortical visual impairment flash visual evoked potentials periventricular leucomalacia stimulation frequency in visual evoked potentials visual evoked potentials Cytomegalovirus retinitis cytomegalovirus retinitis retinal detachment cytomegalovirus highly active antiretroviral therapy Incidence postnatal weight gain retinopathy of prematurity risk factors weight gain proportion Ophthalmology Jayashree Purkayastha verfasserin aut Manali Hazarika verfasserin aut Raghuvamsi Chaitra verfasserin aut K Mithun Adith verfasserin aut In Indian Journal of Ophthalmology Wolters Kluwer Medknow Publications, 2005 61(2013), 11, Seite 640-644 (DE-627)485243563 (DE-600)2185999-1 19983689 nnns volume:61 year:2013 number:11 pages:640-644 https://doi.org/10.4103/0301-4738.119347 kostenfrei https://doaj.org/article/eb584feafb6345818c6a8b36d96dbd8a kostenfrei http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=11;spage=640;epage=644;aulast=Rao kostenfrei https://doaj.org/toc/0301-4738 Journal toc kostenfrei https://doaj.org/toc/1998-3689 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 61 2013 11 640-644
allfieldsGer	10.4103/0301-4738.119347 doi (DE-627)DOAJ010749896 (DE-599)DOAJeb584feafb6345818c6a8b36d96dbd8a DE-627 ger DE-627 rakwb eng RE1-994 Krishna A Rao verfasserin aut Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Context: Recent advances in neonatology have influenced the incidence and severity of ROP in a dichotomous fashion. Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthweight < 1500g and/or gestational age ≤ 32 weeks and also those with gestational age < 32 weeks, with birthweight between 1500-2000 g, who were at risk for ROP were selected. Weight gain proportion was measured as weight at 6 weeks minus birthweight divided by birthweight. Statistical Analysis: Univariate and multivariate logistic regression. Results: Incidence of any ROP was 21.6% while severe ROP was 6.7%. Prenatal factors like multiple gestation (P = 0.510) and antenatal steroids (P = 0.104) were not significantly associated with ROP. On multivariate analysis, postnatal factors like weight at birth < 1250 g (P = 0.01) and gestational age between 31-32 weeks (P = 0.02) were independent risk factors for any ROP, while intraventricular hemorrhage (P = 0.03) was the only independent risk factor for severe ROP. Mean birthweight of infants with severe ROP was 1056 μ 207 g (P = 0.004), which was significantly low. After logistic regression, the mean weight gain proportion at 6 weeks, of those neonates with severe ROP was 30%. Conclusions: Low birthweight and prematurity were the most important risk factors for developing any ROP, while intraventricular hemorrhage was the independent risk factor for developing severe ROP. The mean postnatal weight gain at 6 weeks was not statistically significant in neonates with severe ROP. Anterior segment parameter pars plana vitrectomy pentacam silicone oil injection Astigmatism cataract surgery toric lens toric intraocular lens Amblyopia anisometropia occlusion recurrence visual acuity Cortical visual impairment flash visual evoked potentials periventricular leucomalacia stimulation frequency in visual evoked potentials visual evoked potentials Cytomegalovirus retinitis cytomegalovirus retinitis retinal detachment cytomegalovirus highly active antiretroviral therapy Incidence postnatal weight gain retinopathy of prematurity risk factors weight gain proportion Ophthalmology Jayashree Purkayastha verfasserin aut Manali Hazarika verfasserin aut Raghuvamsi Chaitra verfasserin aut K Mithun Adith verfasserin aut In Indian Journal of Ophthalmology Wolters Kluwer Medknow Publications, 2005 61(2013), 11, Seite 640-644 (DE-627)485243563 (DE-600)2185999-1 19983689 nnns volume:61 year:2013 number:11 pages:640-644 https://doi.org/10.4103/0301-4738.119347 kostenfrei https://doaj.org/article/eb584feafb6345818c6a8b36d96dbd8a kostenfrei http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=11;spage=640;epage=644;aulast=Rao kostenfrei https://doaj.org/toc/0301-4738 Journal toc kostenfrei https://doaj.org/toc/1998-3689 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 61 2013 11 640-644
allfieldsSound	10.4103/0301-4738.119347 doi (DE-627)DOAJ010749896 (DE-599)DOAJeb584feafb6345818c6a8b36d96dbd8a DE-627 ger DE-627 rakwb eng RE1-994 Krishna A Rao verfasserin aut Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Context: Recent advances in neonatology have influenced the incidence and severity of ROP in a dichotomous fashion. Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthweight < 1500g and/or gestational age ≤ 32 weeks and also those with gestational age < 32 weeks, with birthweight between 1500-2000 g, who were at risk for ROP were selected. Weight gain proportion was measured as weight at 6 weeks minus birthweight divided by birthweight. Statistical Analysis: Univariate and multivariate logistic regression. Results: Incidence of any ROP was 21.6% while severe ROP was 6.7%. Prenatal factors like multiple gestation (P = 0.510) and antenatal steroids (P = 0.104) were not significantly associated with ROP. On multivariate analysis, postnatal factors like weight at birth < 1250 g (P = 0.01) and gestational age between 31-32 weeks (P = 0.02) were independent risk factors for any ROP, while intraventricular hemorrhage (P = 0.03) was the only independent risk factor for severe ROP. Mean birthweight of infants with severe ROP was 1056 μ 207 g (P = 0.004), which was significantly low. After logistic regression, the mean weight gain proportion at 6 weeks, of those neonates with severe ROP was 30%. Conclusions: Low birthweight and prematurity were the most important risk factors for developing any ROP, while intraventricular hemorrhage was the independent risk factor for developing severe ROP. The mean postnatal weight gain at 6 weeks was not statistically significant in neonates with severe ROP. Anterior segment parameter pars plana vitrectomy pentacam silicone oil injection Astigmatism cataract surgery toric lens toric intraocular lens Amblyopia anisometropia occlusion recurrence visual acuity Cortical visual impairment flash visual evoked potentials periventricular leucomalacia stimulation frequency in visual evoked potentials visual evoked potentials Cytomegalovirus retinitis cytomegalovirus retinitis retinal detachment cytomegalovirus highly active antiretroviral therapy Incidence postnatal weight gain retinopathy of prematurity risk factors weight gain proportion Ophthalmology Jayashree Purkayastha verfasserin aut Manali Hazarika verfasserin aut Raghuvamsi Chaitra verfasserin aut K Mithun Adith verfasserin aut In Indian Journal of Ophthalmology Wolters Kluwer Medknow Publications, 2005 61(2013), 11, Seite 640-644 (DE-627)485243563 (DE-600)2185999-1 19983689 nnns volume:61 year:2013 number:11 pages:640-644 https://doi.org/10.4103/0301-4738.119347 kostenfrei https://doaj.org/article/eb584feafb6345818c6a8b36d96dbd8a kostenfrei http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=11;spage=640;epage=644;aulast=Rao kostenfrei https://doaj.org/toc/0301-4738 Journal toc kostenfrei https://doaj.org/toc/1998-3689 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 61 2013 11 640-644
language	English
source	In Indian Journal of Ophthalmology 61(2013), 11, Seite 640-644 volume:61 year:2013 number:11 pages:640-644
sourceStr	In Indian Journal of Ophthalmology 61(2013), 11, Seite 640-644 volume:61 year:2013 number:11 pages:640-644
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Anterior segment parameter pars plana vitrectomy pentacam silicone oil injection Astigmatism cataract surgery toric lens toric intraocular lens Amblyopia anisometropia occlusion recurrence visual acuity Cortical visual impairment flash visual evoked potentials periventricular leucomalacia stimulation frequency in visual evoked potentials visual evoked potentials Cytomegalovirus retinitis cytomegalovirus retinitis retinal detachment cytomegalovirus highly active antiretroviral therapy Incidence postnatal weight gain retinopathy of prematurity risk factors weight gain proportion Ophthalmology
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container_title	Indian Journal of Ophthalmology
authorswithroles_txt_mv	Krishna A Rao @@aut@@ Jayashree Purkayastha @@aut@@ Manali Hazarika @@aut@@ Raghuvamsi Chaitra @@aut@@ K Mithun Adith @@aut@@
publishDateDaySort_date	2013-01-01T00:00:00Z
hierarchy_top_id	485243563
id	DOAJ010749896
language_de	englisch
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Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthweight < 1500g and/or gestational age ≤ 32 weeks and also those with gestational age < 32 weeks, with birthweight between 1500-2000 g, who were at risk for ROP were selected. Weight gain proportion was measured as weight at 6 weeks minus birthweight divided by birthweight. Statistical Analysis: Univariate and multivariate logistic regression. Results: Incidence of any ROP was 21.6% while severe ROP was 6.7%. Prenatal factors like multiple gestation (P = 0.510) and antenatal steroids (P = 0.104) were not significantly associated with ROP. On multivariate analysis, postnatal factors like weight at birth < 1250 g (P = 0.01) and gestational age between 31-32 weeks (P = 0.02) were independent risk factors for any ROP, while intraventricular hemorrhage (P = 0.03) was the only independent risk factor for severe ROP. Mean birthweight of infants with severe ROP was 1056 μ 207 g (P = 0.004), which was significantly low. After logistic regression, the mean weight gain proportion at 6 weeks, of those neonates with severe ROP was 30%. Conclusions: Low birthweight and prematurity were the most important risk factors for developing any ROP, while intraventricular hemorrhage was the independent risk factor for developing severe ROP. 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callnumber-first	R - Medicine
author	Krishna A Rao
spellingShingle	Krishna A Rao misc RE1-994 misc Anterior segment parameter misc pars plana vitrectomy misc pentacam misc silicone oil injection misc Astigmatism misc cataract surgery misc toric lens misc toric intraocular lens misc Amblyopia misc anisometropia misc occlusion misc recurrence misc visual acuity misc Cortical visual impairment misc flash visual evoked potentials misc periventricular leucomalacia misc stimulation frequency in visual evoked potentials misc visual evoked potentials misc Cytomegalovirus retinitis misc cytomegalovirus retinitis retinal detachment misc cytomegalovirus misc highly active antiretroviral therapy misc Incidence misc postnatal weight gain misc retinopathy of prematurity misc risk factors misc weight gain proportion misc Ophthalmology Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India
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topic_title	RE1-994 Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India Anterior segment parameter pars plana vitrectomy pentacam silicone oil injection Astigmatism cataract surgery toric lens toric intraocular lens Amblyopia anisometropia occlusion recurrence visual acuity Cortical visual impairment flash visual evoked potentials periventricular leucomalacia stimulation frequency in visual evoked potentials visual evoked potentials Cytomegalovirus retinitis cytomegalovirus retinitis retinal detachment cytomegalovirus highly active antiretroviral therapy Incidence postnatal weight gain retinopathy of prematurity risk factors weight gain proportion
topic	misc RE1-994 misc Anterior segment parameter misc pars plana vitrectomy misc pentacam misc silicone oil injection misc Astigmatism misc cataract surgery misc toric lens misc toric intraocular lens misc Amblyopia misc anisometropia misc occlusion misc recurrence misc visual acuity misc Cortical visual impairment misc flash visual evoked potentials misc periventricular leucomalacia misc stimulation frequency in visual evoked potentials misc visual evoked potentials misc Cytomegalovirus retinitis misc cytomegalovirus retinitis retinal detachment misc cytomegalovirus misc highly active antiretroviral therapy misc Incidence misc postnatal weight gain misc retinopathy of prematurity misc risk factors misc weight gain proportion misc Ophthalmology
topic_unstemmed	misc RE1-994 misc Anterior segment parameter misc pars plana vitrectomy misc pentacam misc silicone oil injection misc Astigmatism misc cataract surgery misc toric lens misc toric intraocular lens misc Amblyopia misc anisometropia misc occlusion misc recurrence misc visual acuity misc Cortical visual impairment misc flash visual evoked potentials misc periventricular leucomalacia misc stimulation frequency in visual evoked potentials misc visual evoked potentials misc Cytomegalovirus retinitis misc cytomegalovirus retinitis retinal detachment misc cytomegalovirus misc highly active antiretroviral therapy misc Incidence misc postnatal weight gain misc retinopathy of prematurity misc risk factors misc weight gain proportion misc Ophthalmology
topic_browse	misc RE1-994 misc Anterior segment parameter misc pars plana vitrectomy misc pentacam misc silicone oil injection misc Astigmatism misc cataract surgery misc toric lens misc toric intraocular lens misc Amblyopia misc anisometropia misc occlusion misc recurrence misc visual acuity misc Cortical visual impairment misc flash visual evoked potentials misc periventricular leucomalacia misc stimulation frequency in visual evoked potentials misc visual evoked potentials misc Cytomegalovirus retinitis misc cytomegalovirus retinitis retinal detachment misc cytomegalovirus misc highly active antiretroviral therapy misc Incidence misc postnatal weight gain misc retinopathy of prematurity misc risk factors misc weight gain proportion misc Ophthalmology
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title	Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India
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title_full	Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India
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title_sort	analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in south india
callnumber	RE1-994
title_auth	Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India
abstract	Context: Recent advances in neonatology have influenced the incidence and severity of ROP in a dichotomous fashion. Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthweight < 1500g and/or gestational age ≤ 32 weeks and also those with gestational age < 32 weeks, with birthweight between 1500-2000 g, who were at risk for ROP were selected. Weight gain proportion was measured as weight at 6 weeks minus birthweight divided by birthweight. Statistical Analysis: Univariate and multivariate logistic regression. Results: Incidence of any ROP was 21.6% while severe ROP was 6.7%. Prenatal factors like multiple gestation (P = 0.510) and antenatal steroids (P = 0.104) were not significantly associated with ROP. On multivariate analysis, postnatal factors like weight at birth < 1250 g (P = 0.01) and gestational age between 31-32 weeks (P = 0.02) were independent risk factors for any ROP, while intraventricular hemorrhage (P = 0.03) was the only independent risk factor for severe ROP. Mean birthweight of infants with severe ROP was 1056 μ 207 g (P = 0.004), which was significantly low. After logistic regression, the mean weight gain proportion at 6 weeks, of those neonates with severe ROP was 30%. Conclusions: Low birthweight and prematurity were the most important risk factors for developing any ROP, while intraventricular hemorrhage was the independent risk factor for developing severe ROP. The mean postnatal weight gain at 6 weeks was not statistically significant in neonates with severe ROP.
abstractGer	Context: Recent advances in neonatology have influenced the incidence and severity of ROP in a dichotomous fashion. Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthweight < 1500g and/or gestational age ≤ 32 weeks and also those with gestational age < 32 weeks, with birthweight between 1500-2000 g, who were at risk for ROP were selected. Weight gain proportion was measured as weight at 6 weeks minus birthweight divided by birthweight. Statistical Analysis: Univariate and multivariate logistic regression. Results: Incidence of any ROP was 21.6% while severe ROP was 6.7%. Prenatal factors like multiple gestation (P = 0.510) and antenatal steroids (P = 0.104) were not significantly associated with ROP. On multivariate analysis, postnatal factors like weight at birth < 1250 g (P = 0.01) and gestational age between 31-32 weeks (P = 0.02) were independent risk factors for any ROP, while intraventricular hemorrhage (P = 0.03) was the only independent risk factor for severe ROP. Mean birthweight of infants with severe ROP was 1056 μ 207 g (P = 0.004), which was significantly low. After logistic regression, the mean weight gain proportion at 6 weeks, of those neonates with severe ROP was 30%. Conclusions: Low birthweight and prematurity were the most important risk factors for developing any ROP, while intraventricular hemorrhage was the independent risk factor for developing severe ROP. The mean postnatal weight gain at 6 weeks was not statistically significant in neonates with severe ROP.
abstract_unstemmed	Context: Recent advances in neonatology have influenced the incidence and severity of ROP in a dichotomous fashion. Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthweight < 1500g and/or gestational age ≤ 32 weeks and also those with gestational age < 32 weeks, with birthweight between 1500-2000 g, who were at risk for ROP were selected. Weight gain proportion was measured as weight at 6 weeks minus birthweight divided by birthweight. Statistical Analysis: Univariate and multivariate logistic regression. Results: Incidence of any ROP was 21.6% while severe ROP was 6.7%. Prenatal factors like multiple gestation (P = 0.510) and antenatal steroids (P = 0.104) were not significantly associated with ROP. On multivariate analysis, postnatal factors like weight at birth < 1250 g (P = 0.01) and gestational age between 31-32 weeks (P = 0.02) were independent risk factors for any ROP, while intraventricular hemorrhage (P = 0.03) was the only independent risk factor for severe ROP. Mean birthweight of infants with severe ROP was 1056 μ 207 g (P = 0.004), which was significantly low. After logistic regression, the mean weight gain proportion at 6 weeks, of those neonates with severe ROP was 30%. Conclusions: Low birthweight and prematurity were the most important risk factors for developing any ROP, while intraventricular hemorrhage was the independent risk factor for developing severe ROP. The mean postnatal weight gain at 6 weeks was not statistically significant in neonates with severe ROP.
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title_short	Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India
url	https://doi.org/10.4103/0301-4738.119347 https://doaj.org/article/eb584feafb6345818c6a8b36d96dbd8a http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=11;spage=640;epage=644;aulast=Rao https://doaj.org/toc/0301-4738 https://doaj.org/toc/1998-3689
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up_date	2024-07-03T16:33:30.035Z
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Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthweight < 1500g and/or gestational age ≤ 32 weeks and also those with gestational age < 32 weeks, with birthweight between 1500-2000 g, who were at risk for ROP were selected. Weight gain proportion was measured as weight at 6 weeks minus birthweight divided by birthweight. Statistical Analysis: Univariate and multivariate logistic regression. Results: Incidence of any ROP was 21.6% while severe ROP was 6.7%. Prenatal factors like multiple gestation (P = 0.510) and antenatal steroids (P = 0.104) were not significantly associated with ROP. On multivariate analysis, postnatal factors like weight at birth < 1250 g (P = 0.01) and gestational age between 31-32 weeks (P = 0.02) were independent risk factors for any ROP, while intraventricular hemorrhage (P = 0.03) was the only independent risk factor for severe ROP. Mean birthweight of infants with severe ROP was 1056 μ 207 g (P = 0.004), which was significantly low. After logistic regression, the mean weight gain proportion at 6 weeks, of those neonates with severe ROP was 30%. Conclusions: Low birthweight and prematurity were the most important risk factors for developing any ROP, while intraventricular hemorrhage was the independent risk factor for developing severe ROP. 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Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India

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