Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India
Context: Recent advances in neonatology have influenced the incidence and severity of ROP in a dichotomous fashion. Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthwei...
Ausführliche Beschreibung
Autor*in: |
Krishna A Rao [verfasserIn] Jayashree Purkayastha [verfasserIn] Manali Hazarika [verfasserIn] Raghuvamsi Chaitra [verfasserIn] K Mithun Adith [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2013 |
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Schlagwörter: |
flash visual evoked potentials stimulation frequency in visual evoked potentials cytomegalovirus retinitis retinal detachment |
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Übergeordnetes Werk: |
In: Indian Journal of Ophthalmology - Wolters Kluwer Medknow Publications, 2005, 61(2013), 11, Seite 640-644 |
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Übergeordnetes Werk: |
volume:61 ; year:2013 ; number:11 ; pages:640-644 |
Links: |
Link aufrufen |
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DOI / URN: |
10.4103/0301-4738.119347 |
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Katalog-ID: |
DOAJ010749896 |
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245 | 1 | 0 | |a Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India |
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520 | |a Context: Recent advances in neonatology have influenced the incidence and severity of ROP in a dichotomous fashion. Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthweight < 1500g and/or gestational age ≤ 32 weeks and also those with gestational age < 32 weeks, with birthweight between 1500-2000 g, who were at risk for ROP were selected. Weight gain proportion was measured as weight at 6 weeks minus birthweight divided by birthweight. Statistical Analysis: Univariate and multivariate logistic regression. Results: Incidence of any ROP was 21.6% while severe ROP was 6.7%. Prenatal factors like multiple gestation (P = 0.510) and antenatal steroids (P = 0.104) were not significantly associated with ROP. On multivariate analysis, postnatal factors like weight at birth < 1250 g (P = 0.01) and gestational age between 31-32 weeks (P = 0.02) were independent risk factors for any ROP, while intraventricular hemorrhage (P = 0.03) was the only independent risk factor for severe ROP. Mean birthweight of infants with severe ROP was 1056 μ 207 g (P = 0.004), which was significantly low. After logistic regression, the mean weight gain proportion at 6 weeks, of those neonates with severe ROP was 30%. Conclusions: Low birthweight and prematurity were the most important risk factors for developing any ROP, while intraventricular hemorrhage was the independent risk factor for developing severe ROP. The mean postnatal weight gain at 6 weeks was not statistically significant in neonates with severe ROP. | ||
650 | 4 | |a Anterior segment parameter | |
650 | 4 | |a pars plana vitrectomy | |
650 | 4 | |a pentacam | |
650 | 4 | |a silicone oil injection | |
650 | 4 | |a Astigmatism | |
650 | 4 | |a cataract surgery | |
650 | 4 | |a toric lens | |
650 | 4 | |a toric intraocular lens | |
650 | 4 | |a Amblyopia | |
650 | 4 | |a anisometropia | |
650 | 4 | |a occlusion | |
650 | 4 | |a recurrence | |
650 | 4 | |a visual acuity | |
650 | 4 | |a Cortical visual impairment | |
650 | 4 | |a flash visual evoked potentials | |
650 | 4 | |a periventricular leucomalacia | |
650 | 4 | |a stimulation frequency in visual evoked potentials | |
650 | 4 | |a visual evoked potentials | |
650 | 4 | |a Cytomegalovirus retinitis | |
650 | 4 | |a cytomegalovirus retinitis retinal detachment | |
650 | 4 | |a cytomegalovirus | |
650 | 4 | |a highly active antiretroviral therapy | |
650 | 4 | |a Incidence | |
650 | 4 | |a postnatal weight gain | |
650 | 4 | |a retinopathy of prematurity | |
650 | 4 | |a risk factors | |
650 | 4 | |a weight gain proportion | |
653 | 0 | |a Ophthalmology | |
700 | 0 | |a Jayashree Purkayastha |e verfasserin |4 aut | |
700 | 0 | |a Manali Hazarika |e verfasserin |4 aut | |
700 | 0 | |a Raghuvamsi Chaitra |e verfasserin |4 aut | |
700 | 0 | |a K Mithun Adith |e verfasserin |4 aut | |
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10.4103/0301-4738.119347 doi (DE-627)DOAJ010749896 (DE-599)DOAJeb584feafb6345818c6a8b36d96dbd8a DE-627 ger DE-627 rakwb eng RE1-994 Krishna A Rao verfasserin aut Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Context: Recent advances in neonatology have influenced the incidence and severity of ROP in a dichotomous fashion. Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthweight < 1500g and/or gestational age ≤ 32 weeks and also those with gestational age < 32 weeks, with birthweight between 1500-2000 g, who were at risk for ROP were selected. Weight gain proportion was measured as weight at 6 weeks minus birthweight divided by birthweight. Statistical Analysis: Univariate and multivariate logistic regression. Results: Incidence of any ROP was 21.6% while severe ROP was 6.7%. Prenatal factors like multiple gestation (P = 0.510) and antenatal steroids (P = 0.104) were not significantly associated with ROP. On multivariate analysis, postnatal factors like weight at birth < 1250 g (P = 0.01) and gestational age between 31-32 weeks (P = 0.02) were independent risk factors for any ROP, while intraventricular hemorrhage (P = 0.03) was the only independent risk factor for severe ROP. Mean birthweight of infants with severe ROP was 1056 μ 207 g (P = 0.004), which was significantly low. After logistic regression, the mean weight gain proportion at 6 weeks, of those neonates with severe ROP was 30%. Conclusions: Low birthweight and prematurity were the most important risk factors for developing any ROP, while intraventricular hemorrhage was the independent risk factor for developing severe ROP. The mean postnatal weight gain at 6 weeks was not statistically significant in neonates with severe ROP. Anterior segment parameter pars plana vitrectomy pentacam silicone oil injection Astigmatism cataract surgery toric lens toric intraocular lens Amblyopia anisometropia occlusion recurrence visual acuity Cortical visual impairment flash visual evoked potentials periventricular leucomalacia stimulation frequency in visual evoked potentials visual evoked potentials Cytomegalovirus retinitis cytomegalovirus retinitis retinal detachment cytomegalovirus highly active antiretroviral therapy Incidence postnatal weight gain retinopathy of prematurity risk factors weight gain proportion Ophthalmology Jayashree Purkayastha verfasserin aut Manali Hazarika verfasserin aut Raghuvamsi Chaitra verfasserin aut K Mithun Adith verfasserin aut In Indian Journal of Ophthalmology Wolters Kluwer Medknow Publications, 2005 61(2013), 11, Seite 640-644 (DE-627)485243563 (DE-600)2185999-1 19983689 nnns volume:61 year:2013 number:11 pages:640-644 https://doi.org/10.4103/0301-4738.119347 kostenfrei https://doaj.org/article/eb584feafb6345818c6a8b36d96dbd8a kostenfrei http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=11;spage=640;epage=644;aulast=Rao kostenfrei https://doaj.org/toc/0301-4738 Journal toc kostenfrei https://doaj.org/toc/1998-3689 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 61 2013 11 640-644 |
spelling |
10.4103/0301-4738.119347 doi (DE-627)DOAJ010749896 (DE-599)DOAJeb584feafb6345818c6a8b36d96dbd8a DE-627 ger DE-627 rakwb eng RE1-994 Krishna A Rao verfasserin aut Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Context: Recent advances in neonatology have influenced the incidence and severity of ROP in a dichotomous fashion. Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthweight < 1500g and/or gestational age ≤ 32 weeks and also those with gestational age < 32 weeks, with birthweight between 1500-2000 g, who were at risk for ROP were selected. Weight gain proportion was measured as weight at 6 weeks minus birthweight divided by birthweight. Statistical Analysis: Univariate and multivariate logistic regression. Results: Incidence of any ROP was 21.6% while severe ROP was 6.7%. Prenatal factors like multiple gestation (P = 0.510) and antenatal steroids (P = 0.104) were not significantly associated with ROP. On multivariate analysis, postnatal factors like weight at birth < 1250 g (P = 0.01) and gestational age between 31-32 weeks (P = 0.02) were independent risk factors for any ROP, while intraventricular hemorrhage (P = 0.03) was the only independent risk factor for severe ROP. Mean birthweight of infants with severe ROP was 1056 μ 207 g (P = 0.004), which was significantly low. After logistic regression, the mean weight gain proportion at 6 weeks, of those neonates with severe ROP was 30%. Conclusions: Low birthweight and prematurity were the most important risk factors for developing any ROP, while intraventricular hemorrhage was the independent risk factor for developing severe ROP. The mean postnatal weight gain at 6 weeks was not statistically significant in neonates with severe ROP. Anterior segment parameter pars plana vitrectomy pentacam silicone oil injection Astigmatism cataract surgery toric lens toric intraocular lens Amblyopia anisometropia occlusion recurrence visual acuity Cortical visual impairment flash visual evoked potentials periventricular leucomalacia stimulation frequency in visual evoked potentials visual evoked potentials Cytomegalovirus retinitis cytomegalovirus retinitis retinal detachment cytomegalovirus highly active antiretroviral therapy Incidence postnatal weight gain retinopathy of prematurity risk factors weight gain proportion Ophthalmology Jayashree Purkayastha verfasserin aut Manali Hazarika verfasserin aut Raghuvamsi Chaitra verfasserin aut K Mithun Adith verfasserin aut In Indian Journal of Ophthalmology Wolters Kluwer Medknow Publications, 2005 61(2013), 11, Seite 640-644 (DE-627)485243563 (DE-600)2185999-1 19983689 nnns volume:61 year:2013 number:11 pages:640-644 https://doi.org/10.4103/0301-4738.119347 kostenfrei https://doaj.org/article/eb584feafb6345818c6a8b36d96dbd8a kostenfrei http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=11;spage=640;epage=644;aulast=Rao kostenfrei https://doaj.org/toc/0301-4738 Journal toc kostenfrei https://doaj.org/toc/1998-3689 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 61 2013 11 640-644 |
allfields_unstemmed |
10.4103/0301-4738.119347 doi (DE-627)DOAJ010749896 (DE-599)DOAJeb584feafb6345818c6a8b36d96dbd8a DE-627 ger DE-627 rakwb eng RE1-994 Krishna A Rao verfasserin aut Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Context: Recent advances in neonatology have influenced the incidence and severity of ROP in a dichotomous fashion. Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthweight < 1500g and/or gestational age ≤ 32 weeks and also those with gestational age < 32 weeks, with birthweight between 1500-2000 g, who were at risk for ROP were selected. Weight gain proportion was measured as weight at 6 weeks minus birthweight divided by birthweight. Statistical Analysis: Univariate and multivariate logistic regression. Results: Incidence of any ROP was 21.6% while severe ROP was 6.7%. Prenatal factors like multiple gestation (P = 0.510) and antenatal steroids (P = 0.104) were not significantly associated with ROP. On multivariate analysis, postnatal factors like weight at birth < 1250 g (P = 0.01) and gestational age between 31-32 weeks (P = 0.02) were independent risk factors for any ROP, while intraventricular hemorrhage (P = 0.03) was the only independent risk factor for severe ROP. Mean birthweight of infants with severe ROP was 1056 μ 207 g (P = 0.004), which was significantly low. After logistic regression, the mean weight gain proportion at 6 weeks, of those neonates with severe ROP was 30%. Conclusions: Low birthweight and prematurity were the most important risk factors for developing any ROP, while intraventricular hemorrhage was the independent risk factor for developing severe ROP. The mean postnatal weight gain at 6 weeks was not statistically significant in neonates with severe ROP. Anterior segment parameter pars plana vitrectomy pentacam silicone oil injection Astigmatism cataract surgery toric lens toric intraocular lens Amblyopia anisometropia occlusion recurrence visual acuity Cortical visual impairment flash visual evoked potentials periventricular leucomalacia stimulation frequency in visual evoked potentials visual evoked potentials Cytomegalovirus retinitis cytomegalovirus retinitis retinal detachment cytomegalovirus highly active antiretroviral therapy Incidence postnatal weight gain retinopathy of prematurity risk factors weight gain proportion Ophthalmology Jayashree Purkayastha verfasserin aut Manali Hazarika verfasserin aut Raghuvamsi Chaitra verfasserin aut K Mithun Adith verfasserin aut In Indian Journal of Ophthalmology Wolters Kluwer Medknow Publications, 2005 61(2013), 11, Seite 640-644 (DE-627)485243563 (DE-600)2185999-1 19983689 nnns volume:61 year:2013 number:11 pages:640-644 https://doi.org/10.4103/0301-4738.119347 kostenfrei https://doaj.org/article/eb584feafb6345818c6a8b36d96dbd8a kostenfrei http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=11;spage=640;epage=644;aulast=Rao kostenfrei https://doaj.org/toc/0301-4738 Journal toc kostenfrei https://doaj.org/toc/1998-3689 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 61 2013 11 640-644 |
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10.4103/0301-4738.119347 doi (DE-627)DOAJ010749896 (DE-599)DOAJeb584feafb6345818c6a8b36d96dbd8a DE-627 ger DE-627 rakwb eng RE1-994 Krishna A Rao verfasserin aut Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Context: Recent advances in neonatology have influenced the incidence and severity of ROP in a dichotomous fashion. Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthweight < 1500g and/or gestational age ≤ 32 weeks and also those with gestational age < 32 weeks, with birthweight between 1500-2000 g, who were at risk for ROP were selected. Weight gain proportion was measured as weight at 6 weeks minus birthweight divided by birthweight. Statistical Analysis: Univariate and multivariate logistic regression. Results: Incidence of any ROP was 21.6% while severe ROP was 6.7%. Prenatal factors like multiple gestation (P = 0.510) and antenatal steroids (P = 0.104) were not significantly associated with ROP. On multivariate analysis, postnatal factors like weight at birth < 1250 g (P = 0.01) and gestational age between 31-32 weeks (P = 0.02) were independent risk factors for any ROP, while intraventricular hemorrhage (P = 0.03) was the only independent risk factor for severe ROP. Mean birthweight of infants with severe ROP was 1056 μ 207 g (P = 0.004), which was significantly low. After logistic regression, the mean weight gain proportion at 6 weeks, of those neonates with severe ROP was 30%. Conclusions: Low birthweight and prematurity were the most important risk factors for developing any ROP, while intraventricular hemorrhage was the independent risk factor for developing severe ROP. The mean postnatal weight gain at 6 weeks was not statistically significant in neonates with severe ROP. Anterior segment parameter pars plana vitrectomy pentacam silicone oil injection Astigmatism cataract surgery toric lens toric intraocular lens Amblyopia anisometropia occlusion recurrence visual acuity Cortical visual impairment flash visual evoked potentials periventricular leucomalacia stimulation frequency in visual evoked potentials visual evoked potentials Cytomegalovirus retinitis cytomegalovirus retinitis retinal detachment cytomegalovirus highly active antiretroviral therapy Incidence postnatal weight gain retinopathy of prematurity risk factors weight gain proportion Ophthalmology Jayashree Purkayastha verfasserin aut Manali Hazarika verfasserin aut Raghuvamsi Chaitra verfasserin aut K Mithun Adith verfasserin aut In Indian Journal of Ophthalmology Wolters Kluwer Medknow Publications, 2005 61(2013), 11, Seite 640-644 (DE-627)485243563 (DE-600)2185999-1 19983689 nnns volume:61 year:2013 number:11 pages:640-644 https://doi.org/10.4103/0301-4738.119347 kostenfrei https://doaj.org/article/eb584feafb6345818c6a8b36d96dbd8a kostenfrei http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=11;spage=640;epage=644;aulast=Rao kostenfrei https://doaj.org/toc/0301-4738 Journal toc kostenfrei https://doaj.org/toc/1998-3689 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 61 2013 11 640-644 |
allfieldsSound |
10.4103/0301-4738.119347 doi (DE-627)DOAJ010749896 (DE-599)DOAJeb584feafb6345818c6a8b36d96dbd8a DE-627 ger DE-627 rakwb eng RE1-994 Krishna A Rao verfasserin aut Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Context: Recent advances in neonatology have influenced the incidence and severity of ROP in a dichotomous fashion. Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthweight < 1500g and/or gestational age ≤ 32 weeks and also those with gestational age < 32 weeks, with birthweight between 1500-2000 g, who were at risk for ROP were selected. Weight gain proportion was measured as weight at 6 weeks minus birthweight divided by birthweight. Statistical Analysis: Univariate and multivariate logistic regression. Results: Incidence of any ROP was 21.6% while severe ROP was 6.7%. Prenatal factors like multiple gestation (P = 0.510) and antenatal steroids (P = 0.104) were not significantly associated with ROP. On multivariate analysis, postnatal factors like weight at birth < 1250 g (P = 0.01) and gestational age between 31-32 weeks (P = 0.02) were independent risk factors for any ROP, while intraventricular hemorrhage (P = 0.03) was the only independent risk factor for severe ROP. Mean birthweight of infants with severe ROP was 1056 μ 207 g (P = 0.004), which was significantly low. After logistic regression, the mean weight gain proportion at 6 weeks, of those neonates with severe ROP was 30%. Conclusions: Low birthweight and prematurity were the most important risk factors for developing any ROP, while intraventricular hemorrhage was the independent risk factor for developing severe ROP. The mean postnatal weight gain at 6 weeks was not statistically significant in neonates with severe ROP. Anterior segment parameter pars plana vitrectomy pentacam silicone oil injection Astigmatism cataract surgery toric lens toric intraocular lens Amblyopia anisometropia occlusion recurrence visual acuity Cortical visual impairment flash visual evoked potentials periventricular leucomalacia stimulation frequency in visual evoked potentials visual evoked potentials Cytomegalovirus retinitis cytomegalovirus retinitis retinal detachment cytomegalovirus highly active antiretroviral therapy Incidence postnatal weight gain retinopathy of prematurity risk factors weight gain proportion Ophthalmology Jayashree Purkayastha verfasserin aut Manali Hazarika verfasserin aut Raghuvamsi Chaitra verfasserin aut K Mithun Adith verfasserin aut In Indian Journal of Ophthalmology Wolters Kluwer Medknow Publications, 2005 61(2013), 11, Seite 640-644 (DE-627)485243563 (DE-600)2185999-1 19983689 nnns volume:61 year:2013 number:11 pages:640-644 https://doi.org/10.4103/0301-4738.119347 kostenfrei https://doaj.org/article/eb584feafb6345818c6a8b36d96dbd8a kostenfrei http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=11;spage=640;epage=644;aulast=Rao kostenfrei https://doaj.org/toc/0301-4738 Journal toc kostenfrei https://doaj.org/toc/1998-3689 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 61 2013 11 640-644 |
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RE1-994 Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India Anterior segment parameter pars plana vitrectomy pentacam silicone oil injection Astigmatism cataract surgery toric lens toric intraocular lens Amblyopia anisometropia occlusion recurrence visual acuity Cortical visual impairment flash visual evoked potentials periventricular leucomalacia stimulation frequency in visual evoked potentials visual evoked potentials Cytomegalovirus retinitis cytomegalovirus retinitis retinal detachment cytomegalovirus highly active antiretroviral therapy Incidence postnatal weight gain retinopathy of prematurity risk factors weight gain proportion |
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Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India |
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Context: Recent advances in neonatology have influenced the incidence and severity of ROP in a dichotomous fashion. Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthweight < 1500g and/or gestational age ≤ 32 weeks and also those with gestational age < 32 weeks, with birthweight between 1500-2000 g, who were at risk for ROP were selected. Weight gain proportion was measured as weight at 6 weeks minus birthweight divided by birthweight. Statistical Analysis: Univariate and multivariate logistic regression. Results: Incidence of any ROP was 21.6% while severe ROP was 6.7%. Prenatal factors like multiple gestation (P = 0.510) and antenatal steroids (P = 0.104) were not significantly associated with ROP. On multivariate analysis, postnatal factors like weight at birth < 1250 g (P = 0.01) and gestational age between 31-32 weeks (P = 0.02) were independent risk factors for any ROP, while intraventricular hemorrhage (P = 0.03) was the only independent risk factor for severe ROP. Mean birthweight of infants with severe ROP was 1056 μ 207 g (P = 0.004), which was significantly low. After logistic regression, the mean weight gain proportion at 6 weeks, of those neonates with severe ROP was 30%. Conclusions: Low birthweight and prematurity were the most important risk factors for developing any ROP, while intraventricular hemorrhage was the independent risk factor for developing severe ROP. The mean postnatal weight gain at 6 weeks was not statistically significant in neonates with severe ROP. |
abstractGer |
Context: Recent advances in neonatology have influenced the incidence and severity of ROP in a dichotomous fashion. Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthweight < 1500g and/or gestational age ≤ 32 weeks and also those with gestational age < 32 weeks, with birthweight between 1500-2000 g, who were at risk for ROP were selected. Weight gain proportion was measured as weight at 6 weeks minus birthweight divided by birthweight. Statistical Analysis: Univariate and multivariate logistic regression. Results: Incidence of any ROP was 21.6% while severe ROP was 6.7%. Prenatal factors like multiple gestation (P = 0.510) and antenatal steroids (P = 0.104) were not significantly associated with ROP. On multivariate analysis, postnatal factors like weight at birth < 1250 g (P = 0.01) and gestational age between 31-32 weeks (P = 0.02) were independent risk factors for any ROP, while intraventricular hemorrhage (P = 0.03) was the only independent risk factor for severe ROP. Mean birthweight of infants with severe ROP was 1056 μ 207 g (P = 0.004), which was significantly low. After logistic regression, the mean weight gain proportion at 6 weeks, of those neonates with severe ROP was 30%. Conclusions: Low birthweight and prematurity were the most important risk factors for developing any ROP, while intraventricular hemorrhage was the independent risk factor for developing severe ROP. The mean postnatal weight gain at 6 weeks was not statistically significant in neonates with severe ROP. |
abstract_unstemmed |
Context: Recent advances in neonatology have influenced the incidence and severity of ROP in a dichotomous fashion. Aims: To determine the incidence of ROP and to analyse its risk factors. Settings and Design: Prospective clinical case series. Materials and Methods: 282 preterm infants with birthweight < 1500g and/or gestational age ≤ 32 weeks and also those with gestational age < 32 weeks, with birthweight between 1500-2000 g, who were at risk for ROP were selected. Weight gain proportion was measured as weight at 6 weeks minus birthweight divided by birthweight. Statistical Analysis: Univariate and multivariate logistic regression. Results: Incidence of any ROP was 21.6% while severe ROP was 6.7%. Prenatal factors like multiple gestation (P = 0.510) and antenatal steroids (P = 0.104) were not significantly associated with ROP. On multivariate analysis, postnatal factors like weight at birth < 1250 g (P = 0.01) and gestational age between 31-32 weeks (P = 0.02) were independent risk factors for any ROP, while intraventricular hemorrhage (P = 0.03) was the only independent risk factor for severe ROP. Mean birthweight of infants with severe ROP was 1056 μ 207 g (P = 0.004), which was significantly low. After logistic regression, the mean weight gain proportion at 6 weeks, of those neonates with severe ROP was 30%. Conclusions: Low birthweight and prematurity were the most important risk factors for developing any ROP, while intraventricular hemorrhage was the independent risk factor for developing severe ROP. The mean postnatal weight gain at 6 weeks was not statistically significant in neonates with severe ROP. |
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Analysis of prenatal and postnatal risk factors of retinopathy of prematurity in a tertiary care hospital in South India |
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