Comparison of narrow band imaging to white light bronchoscopy for evaluation of histopathological biopsy

Background: It is difficult to detect precancerous lesions such as dysplasia and carcinoma in situ (CIS) by conventional white light bronchoscopy (WLB). Narrow Band Imaging Bronchoscopy (NBI) has been reported to detect such lesions more readily. Objective: The objective of the present study is to c...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Radwa Ahmed Elhefny [verfasserIn] Assem Fouad Elessawy [verfasserIn] Sameh Samy Abou- Beih [verfasserIn] Mohamed Amin Ali [verfasserIn] Mona Ibrahim Ahmed [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2016

Schlagwörter:	Narrow band imaging (NBI) White light bronchoscopy (WLB) Premalignant lesions Carcinoma in situ

Übergeordnetes Werk:	In: Egyptian Journal of Chest Disease and Tuberculosis - Wolters Kluwer Medknow Publications, 2016, 65(2016), 1, Seite 341-347
Übergeordnetes Werk:	volume:65 ; year:2016 ; number:1 ; pages:341-347

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1016/j.ejcdt.2015.09.004

Katalog-ID:	DOAJ010862226

Internformat


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520			\|a Background: It is difficult to detect precancerous lesions such as dysplasia and carcinoma in situ (CIS) by conventional white light bronchoscopy (WLB). Narrow Band Imaging Bronchoscopy (NBI) has been reported to detect such lesions more readily. Objective: The objective of the present study is to characterize the appearance of different airway mucosal lesions under NBI mode and to evaluate the role of NBI compared to WLB in diagnosis of premalignant and malignant lesions. Methods: 30 patients presented with radiological changes to chest department in Fayoum University Hospital. They were subjected to full airway examination by fiberoptic bronchoscopy first under WLB then under NBI. Biopsies were taken from susceptible lesions; pathological interpretation was performed. Results: 18 patients (60%) were proved by NBI to have invasive carcinoma compared to 11 patients (36.7%) by WLB. 3 patients (10%) were proved by NBI to have severe dysplasia/CIS compared to 6 patients (20%) by WLB. 3 patients (10%) were proved by NBI to have mild/moderate dysplasia compared to 4 patients (13.3%) by WLB (p value = 0.03). The sensitivity of both WLB and NBI (76.9%) is better than WLB alone or NBI alone (9.1% and 57.1% respectively) in detecting premalignant lesions while the sensitivity of both WLB and NBI (52.6%) is less than WLB alone (55.6%) and better than NBI alone (26.7%) in detecting malignant lesions. Conclusion: NBI can be used in combination with WLB to improve detection of premalignant lesions. It influences biopsy selection and therapeutic planning.
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650		4	\|a Premalignant lesions
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700	0		\|a Mona Ibrahim Ahmed \|e verfasserin \|4 aut
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matchkey_str	article:20909950:2016----::oprsnfarwadmgntwieihbococpfrvlain
hierarchy_sort_str	2016
callnumber-subject-code	RC
publishDate	2016
allfields	10.1016/j.ejcdt.2015.09.004 doi (DE-627)DOAJ010862226 (DE-599)DOAJdabb8b30c3de439283360725984ad2ec DE-627 ger DE-627 rakwb eng RC705-779 Radwa Ahmed Elhefny verfasserin aut Comparison of narrow band imaging to white light bronchoscopy for evaluation of histopathological biopsy 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: It is difficult to detect precancerous lesions such as dysplasia and carcinoma in situ (CIS) by conventional white light bronchoscopy (WLB). Narrow Band Imaging Bronchoscopy (NBI) has been reported to detect such lesions more readily. Objective: The objective of the present study is to characterize the appearance of different airway mucosal lesions under NBI mode and to evaluate the role of NBI compared to WLB in diagnosis of premalignant and malignant lesions. Methods: 30 patients presented with radiological changes to chest department in Fayoum University Hospital. They were subjected to full airway examination by fiberoptic bronchoscopy first under WLB then under NBI. Biopsies were taken from susceptible lesions; pathological interpretation was performed. Results: 18 patients (60%) were proved by NBI to have invasive carcinoma compared to 11 patients (36.7%) by WLB. 3 patients (10%) were proved by NBI to have severe dysplasia/CIS compared to 6 patients (20%) by WLB. 3 patients (10%) were proved by NBI to have mild/moderate dysplasia compared to 4 patients (13.3%) by WLB (p value = 0.03). The sensitivity of both WLB and NBI (76.9%) is better than WLB alone or NBI alone (9.1% and 57.1% respectively) in detecting premalignant lesions while the sensitivity of both WLB and NBI (52.6%) is less than WLB alone (55.6%) and better than NBI alone (26.7%) in detecting malignant lesions. Conclusion: NBI can be used in combination with WLB to improve detection of premalignant lesions. It influences biopsy selection and therapeutic planning. Narrow band imaging (NBI) White light bronchoscopy (WLB) Premalignant lesions Carcinoma in situ Diseases of the respiratory system Assem Fouad Elessawy verfasserin aut Sameh Samy Abou- Beih verfasserin aut Mohamed Amin Ali verfasserin aut Mona Ibrahim Ahmed verfasserin aut In Egyptian Journal of Chest Disease and Tuberculosis Wolters Kluwer Medknow Publications, 2016 65(2016), 1, Seite 341-347 (DE-627)820688878 (DE-600)2814778-9 20909950 nnns volume:65 year:2016 number:1 pages:341-347 https://doi.org/10.1016/j.ejcdt.2015.09.004 kostenfrei https://doaj.org/article/dabb8b30c3de439283360725984ad2ec kostenfrei http://www.sciencedirect.com/science/article/pii/S0422763815300455 kostenfrei https://doaj.org/toc/0422-7638 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 65 2016 1 341-347
spelling	10.1016/j.ejcdt.2015.09.004 doi (DE-627)DOAJ010862226 (DE-599)DOAJdabb8b30c3de439283360725984ad2ec DE-627 ger DE-627 rakwb eng RC705-779 Radwa Ahmed Elhefny verfasserin aut Comparison of narrow band imaging to white light bronchoscopy for evaluation of histopathological biopsy 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: It is difficult to detect precancerous lesions such as dysplasia and carcinoma in situ (CIS) by conventional white light bronchoscopy (WLB). Narrow Band Imaging Bronchoscopy (NBI) has been reported to detect such lesions more readily. Objective: The objective of the present study is to characterize the appearance of different airway mucosal lesions under NBI mode and to evaluate the role of NBI compared to WLB in diagnosis of premalignant and malignant lesions. Methods: 30 patients presented with radiological changes to chest department in Fayoum University Hospital. They were subjected to full airway examination by fiberoptic bronchoscopy first under WLB then under NBI. Biopsies were taken from susceptible lesions; pathological interpretation was performed. Results: 18 patients (60%) were proved by NBI to have invasive carcinoma compared to 11 patients (36.7%) by WLB. 3 patients (10%) were proved by NBI to have severe dysplasia/CIS compared to 6 patients (20%) by WLB. 3 patients (10%) were proved by NBI to have mild/moderate dysplasia compared to 4 patients (13.3%) by WLB (p value = 0.03). The sensitivity of both WLB and NBI (76.9%) is better than WLB alone or NBI alone (9.1% and 57.1% respectively) in detecting premalignant lesions while the sensitivity of both WLB and NBI (52.6%) is less than WLB alone (55.6%) and better than NBI alone (26.7%) in detecting malignant lesions. Conclusion: NBI can be used in combination with WLB to improve detection of premalignant lesions. It influences biopsy selection and therapeutic planning. Narrow band imaging (NBI) White light bronchoscopy (WLB) Premalignant lesions Carcinoma in situ Diseases of the respiratory system Assem Fouad Elessawy verfasserin aut Sameh Samy Abou- Beih verfasserin aut Mohamed Amin Ali verfasserin aut Mona Ibrahim Ahmed verfasserin aut In Egyptian Journal of Chest Disease and Tuberculosis Wolters Kluwer Medknow Publications, 2016 65(2016), 1, Seite 341-347 (DE-627)820688878 (DE-600)2814778-9 20909950 nnns volume:65 year:2016 number:1 pages:341-347 https://doi.org/10.1016/j.ejcdt.2015.09.004 kostenfrei https://doaj.org/article/dabb8b30c3de439283360725984ad2ec kostenfrei http://www.sciencedirect.com/science/article/pii/S0422763815300455 kostenfrei https://doaj.org/toc/0422-7638 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 65 2016 1 341-347
allfields_unstemmed	10.1016/j.ejcdt.2015.09.004 doi (DE-627)DOAJ010862226 (DE-599)DOAJdabb8b30c3de439283360725984ad2ec DE-627 ger DE-627 rakwb eng RC705-779 Radwa Ahmed Elhefny verfasserin aut Comparison of narrow band imaging to white light bronchoscopy for evaluation of histopathological biopsy 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: It is difficult to detect precancerous lesions such as dysplasia and carcinoma in situ (CIS) by conventional white light bronchoscopy (WLB). Narrow Band Imaging Bronchoscopy (NBI) has been reported to detect such lesions more readily. Objective: The objective of the present study is to characterize the appearance of different airway mucosal lesions under NBI mode and to evaluate the role of NBI compared to WLB in diagnosis of premalignant and malignant lesions. Methods: 30 patients presented with radiological changes to chest department in Fayoum University Hospital. They were subjected to full airway examination by fiberoptic bronchoscopy first under WLB then under NBI. Biopsies were taken from susceptible lesions; pathological interpretation was performed. Results: 18 patients (60%) were proved by NBI to have invasive carcinoma compared to 11 patients (36.7%) by WLB. 3 patients (10%) were proved by NBI to have severe dysplasia/CIS compared to 6 patients (20%) by WLB. 3 patients (10%) were proved by NBI to have mild/moderate dysplasia compared to 4 patients (13.3%) by WLB (p value = 0.03). The sensitivity of both WLB and NBI (76.9%) is better than WLB alone or NBI alone (9.1% and 57.1% respectively) in detecting premalignant lesions while the sensitivity of both WLB and NBI (52.6%) is less than WLB alone (55.6%) and better than NBI alone (26.7%) in detecting malignant lesions. Conclusion: NBI can be used in combination with WLB to improve detection of premalignant lesions. It influences biopsy selection and therapeutic planning. Narrow band imaging (NBI) White light bronchoscopy (WLB) Premalignant lesions Carcinoma in situ Diseases of the respiratory system Assem Fouad Elessawy verfasserin aut Sameh Samy Abou- Beih verfasserin aut Mohamed Amin Ali verfasserin aut Mona Ibrahim Ahmed verfasserin aut In Egyptian Journal of Chest Disease and Tuberculosis Wolters Kluwer Medknow Publications, 2016 65(2016), 1, Seite 341-347 (DE-627)820688878 (DE-600)2814778-9 20909950 nnns volume:65 year:2016 number:1 pages:341-347 https://doi.org/10.1016/j.ejcdt.2015.09.004 kostenfrei https://doaj.org/article/dabb8b30c3de439283360725984ad2ec kostenfrei http://www.sciencedirect.com/science/article/pii/S0422763815300455 kostenfrei https://doaj.org/toc/0422-7638 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 65 2016 1 341-347
allfieldsGer	10.1016/j.ejcdt.2015.09.004 doi (DE-627)DOAJ010862226 (DE-599)DOAJdabb8b30c3de439283360725984ad2ec DE-627 ger DE-627 rakwb eng RC705-779 Radwa Ahmed Elhefny verfasserin aut Comparison of narrow band imaging to white light bronchoscopy for evaluation of histopathological biopsy 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: It is difficult to detect precancerous lesions such as dysplasia and carcinoma in situ (CIS) by conventional white light bronchoscopy (WLB). Narrow Band Imaging Bronchoscopy (NBI) has been reported to detect such lesions more readily. Objective: The objective of the present study is to characterize the appearance of different airway mucosal lesions under NBI mode and to evaluate the role of NBI compared to WLB in diagnosis of premalignant and malignant lesions. Methods: 30 patients presented with radiological changes to chest department in Fayoum University Hospital. They were subjected to full airway examination by fiberoptic bronchoscopy first under WLB then under NBI. Biopsies were taken from susceptible lesions; pathological interpretation was performed. Results: 18 patients (60%) were proved by NBI to have invasive carcinoma compared to 11 patients (36.7%) by WLB. 3 patients (10%) were proved by NBI to have severe dysplasia/CIS compared to 6 patients (20%) by WLB. 3 patients (10%) were proved by NBI to have mild/moderate dysplasia compared to 4 patients (13.3%) by WLB (p value = 0.03). The sensitivity of both WLB and NBI (76.9%) is better than WLB alone or NBI alone (9.1% and 57.1% respectively) in detecting premalignant lesions while the sensitivity of both WLB and NBI (52.6%) is less than WLB alone (55.6%) and better than NBI alone (26.7%) in detecting malignant lesions. Conclusion: NBI can be used in combination with WLB to improve detection of premalignant lesions. It influences biopsy selection and therapeutic planning. Narrow band imaging (NBI) White light bronchoscopy (WLB) Premalignant lesions Carcinoma in situ Diseases of the respiratory system Assem Fouad Elessawy verfasserin aut Sameh Samy Abou- Beih verfasserin aut Mohamed Amin Ali verfasserin aut Mona Ibrahim Ahmed verfasserin aut In Egyptian Journal of Chest Disease and Tuberculosis Wolters Kluwer Medknow Publications, 2016 65(2016), 1, Seite 341-347 (DE-627)820688878 (DE-600)2814778-9 20909950 nnns volume:65 year:2016 number:1 pages:341-347 https://doi.org/10.1016/j.ejcdt.2015.09.004 kostenfrei https://doaj.org/article/dabb8b30c3de439283360725984ad2ec kostenfrei http://www.sciencedirect.com/science/article/pii/S0422763815300455 kostenfrei https://doaj.org/toc/0422-7638 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 65 2016 1 341-347
allfieldsSound	10.1016/j.ejcdt.2015.09.004 doi (DE-627)DOAJ010862226 (DE-599)DOAJdabb8b30c3de439283360725984ad2ec DE-627 ger DE-627 rakwb eng RC705-779 Radwa Ahmed Elhefny verfasserin aut Comparison of narrow band imaging to white light bronchoscopy for evaluation of histopathological biopsy 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: It is difficult to detect precancerous lesions such as dysplasia and carcinoma in situ (CIS) by conventional white light bronchoscopy (WLB). Narrow Band Imaging Bronchoscopy (NBI) has been reported to detect such lesions more readily. Objective: The objective of the present study is to characterize the appearance of different airway mucosal lesions under NBI mode and to evaluate the role of NBI compared to WLB in diagnosis of premalignant and malignant lesions. Methods: 30 patients presented with radiological changes to chest department in Fayoum University Hospital. They were subjected to full airway examination by fiberoptic bronchoscopy first under WLB then under NBI. Biopsies were taken from susceptible lesions; pathological interpretation was performed. Results: 18 patients (60%) were proved by NBI to have invasive carcinoma compared to 11 patients (36.7%) by WLB. 3 patients (10%) were proved by NBI to have severe dysplasia/CIS compared to 6 patients (20%) by WLB. 3 patients (10%) were proved by NBI to have mild/moderate dysplasia compared to 4 patients (13.3%) by WLB (p value = 0.03). The sensitivity of both WLB and NBI (76.9%) is better than WLB alone or NBI alone (9.1% and 57.1% respectively) in detecting premalignant lesions while the sensitivity of both WLB and NBI (52.6%) is less than WLB alone (55.6%) and better than NBI alone (26.7%) in detecting malignant lesions. Conclusion: NBI can be used in combination with WLB to improve detection of premalignant lesions. It influences biopsy selection and therapeutic planning. Narrow band imaging (NBI) White light bronchoscopy (WLB) Premalignant lesions Carcinoma in situ Diseases of the respiratory system Assem Fouad Elessawy verfasserin aut Sameh Samy Abou- Beih verfasserin aut Mohamed Amin Ali verfasserin aut Mona Ibrahim Ahmed verfasserin aut In Egyptian Journal of Chest Disease and Tuberculosis Wolters Kluwer Medknow Publications, 2016 65(2016), 1, Seite 341-347 (DE-627)820688878 (DE-600)2814778-9 20909950 nnns volume:65 year:2016 number:1 pages:341-347 https://doi.org/10.1016/j.ejcdt.2015.09.004 kostenfrei https://doaj.org/article/dabb8b30c3de439283360725984ad2ec kostenfrei http://www.sciencedirect.com/science/article/pii/S0422763815300455 kostenfrei https://doaj.org/toc/0422-7638 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 65 2016 1 341-347
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callnumber-first	R - Medicine
author	Radwa Ahmed Elhefny
spellingShingle	Radwa Ahmed Elhefny misc RC705-779 misc Narrow band imaging (NBI) misc White light bronchoscopy (WLB) misc Premalignant lesions misc Carcinoma in situ misc Diseases of the respiratory system Comparison of narrow band imaging to white light bronchoscopy for evaluation of histopathological biopsy
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topic_title	RC705-779 Comparison of narrow band imaging to white light bronchoscopy for evaluation of histopathological biopsy Narrow band imaging (NBI) White light bronchoscopy (WLB) Premalignant lesions Carcinoma in situ
topic	misc RC705-779 misc Narrow band imaging (NBI) misc White light bronchoscopy (WLB) misc Premalignant lesions misc Carcinoma in situ misc Diseases of the respiratory system
topic_unstemmed	misc RC705-779 misc Narrow band imaging (NBI) misc White light bronchoscopy (WLB) misc Premalignant lesions misc Carcinoma in situ misc Diseases of the respiratory system
topic_browse	misc RC705-779 misc Narrow band imaging (NBI) misc White light bronchoscopy (WLB) misc Premalignant lesions misc Carcinoma in situ misc Diseases of the respiratory system
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title	Comparison of narrow band imaging to white light bronchoscopy for evaluation of histopathological biopsy
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title_full	Comparison of narrow band imaging to white light bronchoscopy for evaluation of histopathological biopsy
author_sort	Radwa Ahmed Elhefny
journal	Egyptian Journal of Chest Disease and Tuberculosis
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author_browse	Radwa Ahmed Elhefny Assem Fouad Elessawy Sameh Samy Abou- Beih Mohamed Amin Ali Mona Ibrahim Ahmed
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title_sort	comparison of narrow band imaging to white light bronchoscopy for evaluation of histopathological biopsy
callnumber	RC705-779
title_auth	Comparison of narrow band imaging to white light bronchoscopy for evaluation of histopathological biopsy
abstract	Background: It is difficult to detect precancerous lesions such as dysplasia and carcinoma in situ (CIS) by conventional white light bronchoscopy (WLB). Narrow Band Imaging Bronchoscopy (NBI) has been reported to detect such lesions more readily. Objective: The objective of the present study is to characterize the appearance of different airway mucosal lesions under NBI mode and to evaluate the role of NBI compared to WLB in diagnosis of premalignant and malignant lesions. Methods: 30 patients presented with radiological changes to chest department in Fayoum University Hospital. They were subjected to full airway examination by fiberoptic bronchoscopy first under WLB then under NBI. Biopsies were taken from susceptible lesions; pathological interpretation was performed. Results: 18 patients (60%) were proved by NBI to have invasive carcinoma compared to 11 patients (36.7%) by WLB. 3 patients (10%) were proved by NBI to have severe dysplasia/CIS compared to 6 patients (20%) by WLB. 3 patients (10%) were proved by NBI to have mild/moderate dysplasia compared to 4 patients (13.3%) by WLB (p value = 0.03). The sensitivity of both WLB and NBI (76.9%) is better than WLB alone or NBI alone (9.1% and 57.1% respectively) in detecting premalignant lesions while the sensitivity of both WLB and NBI (52.6%) is less than WLB alone (55.6%) and better than NBI alone (26.7%) in detecting malignant lesions. Conclusion: NBI can be used in combination with WLB to improve detection of premalignant lesions. It influences biopsy selection and therapeutic planning.
abstractGer	Background: It is difficult to detect precancerous lesions such as dysplasia and carcinoma in situ (CIS) by conventional white light bronchoscopy (WLB). Narrow Band Imaging Bronchoscopy (NBI) has been reported to detect such lesions more readily. Objective: The objective of the present study is to characterize the appearance of different airway mucosal lesions under NBI mode and to evaluate the role of NBI compared to WLB in diagnosis of premalignant and malignant lesions. Methods: 30 patients presented with radiological changes to chest department in Fayoum University Hospital. They were subjected to full airway examination by fiberoptic bronchoscopy first under WLB then under NBI. Biopsies were taken from susceptible lesions; pathological interpretation was performed. Results: 18 patients (60%) were proved by NBI to have invasive carcinoma compared to 11 patients (36.7%) by WLB. 3 patients (10%) were proved by NBI to have severe dysplasia/CIS compared to 6 patients (20%) by WLB. 3 patients (10%) were proved by NBI to have mild/moderate dysplasia compared to 4 patients (13.3%) by WLB (p value = 0.03). The sensitivity of both WLB and NBI (76.9%) is better than WLB alone or NBI alone (9.1% and 57.1% respectively) in detecting premalignant lesions while the sensitivity of both WLB and NBI (52.6%) is less than WLB alone (55.6%) and better than NBI alone (26.7%) in detecting malignant lesions. Conclusion: NBI can be used in combination with WLB to improve detection of premalignant lesions. It influences biopsy selection and therapeutic planning.
abstract_unstemmed	Background: It is difficult to detect precancerous lesions such as dysplasia and carcinoma in situ (CIS) by conventional white light bronchoscopy (WLB). Narrow Band Imaging Bronchoscopy (NBI) has been reported to detect such lesions more readily. Objective: The objective of the present study is to characterize the appearance of different airway mucosal lesions under NBI mode and to evaluate the role of NBI compared to WLB in diagnosis of premalignant and malignant lesions. Methods: 30 patients presented with radiological changes to chest department in Fayoum University Hospital. They were subjected to full airway examination by fiberoptic bronchoscopy first under WLB then under NBI. Biopsies were taken from susceptible lesions; pathological interpretation was performed. Results: 18 patients (60%) were proved by NBI to have invasive carcinoma compared to 11 patients (36.7%) by WLB. 3 patients (10%) were proved by NBI to have severe dysplasia/CIS compared to 6 patients (20%) by WLB. 3 patients (10%) were proved by NBI to have mild/moderate dysplasia compared to 4 patients (13.3%) by WLB (p value = 0.03). The sensitivity of both WLB and NBI (76.9%) is better than WLB alone or NBI alone (9.1% and 57.1% respectively) in detecting premalignant lesions while the sensitivity of both WLB and NBI (52.6%) is less than WLB alone (55.6%) and better than NBI alone (26.7%) in detecting malignant lesions. Conclusion: NBI can be used in combination with WLB to improve detection of premalignant lesions. It influences biopsy selection and therapeutic planning.
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title_short	Comparison of narrow band imaging to white light bronchoscopy for evaluation of histopathological biopsy
url	https://doi.org/10.1016/j.ejcdt.2015.09.004 https://doaj.org/article/dabb8b30c3de439283360725984ad2ec http://www.sciencedirect.com/science/article/pii/S0422763815300455 https://doaj.org/toc/0422-7638
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author2	Assem Fouad Elessawy Sameh Samy Abou- Beih Mohamed Amin Ali Mona Ibrahim Ahmed
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up_date	2024-07-03T17:10:11.562Z
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The sensitivity of both WLB and NBI (76.9%) is better than WLB alone or NBI alone (9.1% and 57.1% respectively) in detecting premalignant lesions while the sensitivity of both WLB and NBI (52.6%) is less than WLB alone (55.6%) and better than NBI alone (26.7%) in detecting malignant lesions. Conclusion: NBI can be used in combination with WLB to improve detection of premalignant lesions. 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Comparison of narrow band imaging to white light bronchoscopy for evaluation of histopathological biopsy

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