The ability inhibition Gumboro disease virus in 3-week-old chickens of chicken Interferon Alpha
Virus-infectious diseases are permanent threats and cause serious lost for chicken industry of our country. Recombinant chicken interferon alpha (rChIFN-α) were expressed successfully on yeast pichia pastorisand was functional antivirus. The objective of this study was deter...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Nguyễn Thị Thanh Giang [verfasserIn] Hồ Quảng Đồ [verfasserIn] Nguyễn Đăng Quân [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2020 |
|---|
| Schlagwörter: |
|---|
| Übergeordnetes Werk: |
In: Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ - HO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCE, 2021, 15(2020), 1, Seite 5-15 |
|---|---|
| Übergeordnetes Werk: |
volume:15 ; year:2020 ; number:1 ; pages:5-15 |
| Links: |
Link aufrufen |
|---|
| DOI / URN: |
10.46223/HCMCOUJS.tech.vi.15.1.1017.2020 |
|---|
| Katalog-ID: |
DOAJ011412178 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | DOAJ011412178 | ||
| 003 | DE-627 | ||
| 005 | 20230310034148.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 230225s2020 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.46223/HCMCOUJS.tech.vi.15.1.1017.2020 |2 doi | |
| 035 | |a (DE-627)DOAJ011412178 | ||
| 035 | |a (DE-599)DOAJ321d56aae3e34b2c9344f7eec6a4aa04 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 050 | 0 | |a TP248.13-248.65 | |
| 100 | 0 | |a Nguyễn Thị Thanh Giang |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The ability inhibition Gumboro disease virus in 3-week-old chickens of chicken Interferon Alpha |
| 264 | 1 | |c 2020 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 520 | |a Virus-infectious diseases are permanent threats and cause serious lost for chicken industry of our country. Recombinant chicken interferon alpha (rChIFN-α) were expressed successfully on yeast pichia pastorisand was functional antivirus. The objective of this study was determined recombinant chicken interferon alpha (rChIFN-α) effectiveness in 3-week-old chickens infected infectious bursal diseasevirus (IBDV).In the present study, we used 3-week-old chickens without IBDV antibodies. Each 3-week-old chickens were infected virulent Gumboro disease virus with dose of 5x104ELD50. After 24 hours infected virus, they were exposed to eye/nasal drops with one of doses 0.1 μg/chick; 1 μg/chick; 10 μg/chick or 100 μg/chick. The results suggested treatment with rChIFN-α 0.1 μg/chick, the chickens' protected and survival rate were 46.7% and 80% respectively. Group of chickens were treated rChIFN-α 1 μg / chick, the protected and survival rate of chickens respectively 60.0% and 86.7%; The same result with chickens were treated rChIFN-α 10 μg/chick and 100 μg/chick, the chickens' protected and survival rate were 66.7% and 93.3%, respectively. Meanwhile, the positive control group (chicken infected virus, untreated), unprotected chickens (infection rate was 100%) and survival rate was only 60,00%. The negative control (chickens uninfected viruses, untreated with rChIFN-α), completely uninfected and 100% survival chickens. The result suggested that rChIFN-α have effective treating Gumboro disease and depends on the dose used. In addition, the chickens' antibody titres shown that the chickens' immune response in rChIFN-α groups was not different than the chickens infected only Gumboro disease virus, suggested that rChIFN-α did not affect the chickens' immune response. | ||
| 650 | 4 | |a interferon | |
| 650 | 4 | |a gumboro | |
| 650 | 4 | |a gà | |
| 650 | 4 | |a rchifn-α | |
| 653 | 0 | |a Biotechnology | |
| 700 | 0 | |a Hồ Quảng Đồ |e verfasserin |4 aut | |
| 700 | 0 | |a Nguyễn Đăng Quân |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i In |t Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ |d HO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCE, 2021 |g 15(2020), 1, Seite 5-15 |w (DE-627)DOAJ078618703 |x 27349594 |7 nnns |
| 773 | 1 | 8 | |g volume:15 |g year:2020 |g number:1 |g pages:5-15 |
| 856 | 4 | 0 | |u https://doi.org/10.46223/HCMCOUJS.tech.vi.15.1.1017.2020 |z kostenfrei |
| 856 | 4 | 0 | |u https://doaj.org/article/321d56aae3e34b2c9344f7eec6a4aa04 |z kostenfrei |
| 856 | 4 | 0 | |u https://journalofscience.ou.edu.vn/index.php/tech-vi/article/view/1017 |z kostenfrei |
| 856 | 4 | 2 | |u https://doaj.org/toc/2734-9322 |y Journal toc |z kostenfrei |
| 856 | 4 | 2 | |u https://doaj.org/toc/2734-9594 |y Journal toc |z kostenfrei |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a SYSFLAG_A | ||
| 912 | |a GBV_DOAJ | ||
| 951 | |a AR | ||
| 952 | |d 15 |j 2020 |e 1 |h 5-15 | ||
| author_variant |
n t t g nttg h q đ hqđ n đ q nđq |
|---|---|
| matchkey_str |
article:27349594:2020----::haiiyniiinubrdsaeiui3eklciknoc |
| hierarchy_sort_str |
2020 |
| callnumber-subject-code |
TP |
| publishDate |
2020 |
| allfields |
10.46223/HCMCOUJS.tech.vi.15.1.1017.2020 doi (DE-627)DOAJ011412178 (DE-599)DOAJ321d56aae3e34b2c9344f7eec6a4aa04 DE-627 ger DE-627 rakwb eng TP248.13-248.65 Nguyễn Thị Thanh Giang verfasserin aut The ability inhibition Gumboro disease virus in 3-week-old chickens of chicken Interferon Alpha 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Virus-infectious diseases are permanent threats and cause serious lost for chicken industry of our country. Recombinant chicken interferon alpha (rChIFN-α) were expressed successfully on yeast pichia pastorisand was functional antivirus. The objective of this study was determined recombinant chicken interferon alpha (rChIFN-α) effectiveness in 3-week-old chickens infected infectious bursal diseasevirus (IBDV).In the present study, we used 3-week-old chickens without IBDV antibodies. Each 3-week-old chickens were infected virulent Gumboro disease virus with dose of 5x104ELD50. After 24 hours infected virus, they were exposed to eye/nasal drops with one of doses 0.1 μg/chick; 1 μg/chick; 10 μg/chick or 100 μg/chick. The results suggested treatment with rChIFN-α 0.1 μg/chick, the chickens' protected and survival rate were 46.7% and 80% respectively. Group of chickens were treated rChIFN-α 1 μg / chick, the protected and survival rate of chickens respectively 60.0% and 86.7%; The same result with chickens were treated rChIFN-α 10 μg/chick and 100 μg/chick, the chickens' protected and survival rate were 66.7% and 93.3%, respectively. Meanwhile, the positive control group (chicken infected virus, untreated), unprotected chickens (infection rate was 100%) and survival rate was only 60,00%. The negative control (chickens uninfected viruses, untreated with rChIFN-α), completely uninfected and 100% survival chickens. The result suggested that rChIFN-α have effective treating Gumboro disease and depends on the dose used. In addition, the chickens' antibody titres shown that the chickens' immune response in rChIFN-α groups was not different than the chickens infected only Gumboro disease virus, suggested that rChIFN-α did not affect the chickens' immune response. interferon gumboro gà rchifn-α Biotechnology Hồ Quảng Đồ verfasserin aut Nguyễn Đăng Quân verfasserin aut In Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ HO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCE, 2021 15(2020), 1, Seite 5-15 (DE-627)DOAJ078618703 27349594 nnns volume:15 year:2020 number:1 pages:5-15 https://doi.org/10.46223/HCMCOUJS.tech.vi.15.1.1017.2020 kostenfrei https://doaj.org/article/321d56aae3e34b2c9344f7eec6a4aa04 kostenfrei https://journalofscience.ou.edu.vn/index.php/tech-vi/article/view/1017 kostenfrei https://doaj.org/toc/2734-9322 Journal toc kostenfrei https://doaj.org/toc/2734-9594 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 15 2020 1 5-15 |
| spelling |
10.46223/HCMCOUJS.tech.vi.15.1.1017.2020 doi (DE-627)DOAJ011412178 (DE-599)DOAJ321d56aae3e34b2c9344f7eec6a4aa04 DE-627 ger DE-627 rakwb eng TP248.13-248.65 Nguyễn Thị Thanh Giang verfasserin aut The ability inhibition Gumboro disease virus in 3-week-old chickens of chicken Interferon Alpha 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Virus-infectious diseases are permanent threats and cause serious lost for chicken industry of our country. Recombinant chicken interferon alpha (rChIFN-α) were expressed successfully on yeast pichia pastorisand was functional antivirus. The objective of this study was determined recombinant chicken interferon alpha (rChIFN-α) effectiveness in 3-week-old chickens infected infectious bursal diseasevirus (IBDV).In the present study, we used 3-week-old chickens without IBDV antibodies. Each 3-week-old chickens were infected virulent Gumboro disease virus with dose of 5x104ELD50. After 24 hours infected virus, they were exposed to eye/nasal drops with one of doses 0.1 μg/chick; 1 μg/chick; 10 μg/chick or 100 μg/chick. The results suggested treatment with rChIFN-α 0.1 μg/chick, the chickens' protected and survival rate were 46.7% and 80% respectively. Group of chickens were treated rChIFN-α 1 μg / chick, the protected and survival rate of chickens respectively 60.0% and 86.7%; The same result with chickens were treated rChIFN-α 10 μg/chick and 100 μg/chick, the chickens' protected and survival rate were 66.7% and 93.3%, respectively. Meanwhile, the positive control group (chicken infected virus, untreated), unprotected chickens (infection rate was 100%) and survival rate was only 60,00%. The negative control (chickens uninfected viruses, untreated with rChIFN-α), completely uninfected and 100% survival chickens. The result suggested that rChIFN-α have effective treating Gumboro disease and depends on the dose used. In addition, the chickens' antibody titres shown that the chickens' immune response in rChIFN-α groups was not different than the chickens infected only Gumboro disease virus, suggested that rChIFN-α did not affect the chickens' immune response. interferon gumboro gà rchifn-α Biotechnology Hồ Quảng Đồ verfasserin aut Nguyễn Đăng Quân verfasserin aut In Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ HO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCE, 2021 15(2020), 1, Seite 5-15 (DE-627)DOAJ078618703 27349594 nnns volume:15 year:2020 number:1 pages:5-15 https://doi.org/10.46223/HCMCOUJS.tech.vi.15.1.1017.2020 kostenfrei https://doaj.org/article/321d56aae3e34b2c9344f7eec6a4aa04 kostenfrei https://journalofscience.ou.edu.vn/index.php/tech-vi/article/view/1017 kostenfrei https://doaj.org/toc/2734-9322 Journal toc kostenfrei https://doaj.org/toc/2734-9594 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 15 2020 1 5-15 |
| allfields_unstemmed |
10.46223/HCMCOUJS.tech.vi.15.1.1017.2020 doi (DE-627)DOAJ011412178 (DE-599)DOAJ321d56aae3e34b2c9344f7eec6a4aa04 DE-627 ger DE-627 rakwb eng TP248.13-248.65 Nguyễn Thị Thanh Giang verfasserin aut The ability inhibition Gumboro disease virus in 3-week-old chickens of chicken Interferon Alpha 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Virus-infectious diseases are permanent threats and cause serious lost for chicken industry of our country. Recombinant chicken interferon alpha (rChIFN-α) were expressed successfully on yeast pichia pastorisand was functional antivirus. The objective of this study was determined recombinant chicken interferon alpha (rChIFN-α) effectiveness in 3-week-old chickens infected infectious bursal diseasevirus (IBDV).In the present study, we used 3-week-old chickens without IBDV antibodies. Each 3-week-old chickens were infected virulent Gumboro disease virus with dose of 5x104ELD50. After 24 hours infected virus, they were exposed to eye/nasal drops with one of doses 0.1 μg/chick; 1 μg/chick; 10 μg/chick or 100 μg/chick. The results suggested treatment with rChIFN-α 0.1 μg/chick, the chickens' protected and survival rate were 46.7% and 80% respectively. Group of chickens were treated rChIFN-α 1 μg / chick, the protected and survival rate of chickens respectively 60.0% and 86.7%; The same result with chickens were treated rChIFN-α 10 μg/chick and 100 μg/chick, the chickens' protected and survival rate were 66.7% and 93.3%, respectively. Meanwhile, the positive control group (chicken infected virus, untreated), unprotected chickens (infection rate was 100%) and survival rate was only 60,00%. The negative control (chickens uninfected viruses, untreated with rChIFN-α), completely uninfected and 100% survival chickens. The result suggested that rChIFN-α have effective treating Gumboro disease and depends on the dose used. In addition, the chickens' antibody titres shown that the chickens' immune response in rChIFN-α groups was not different than the chickens infected only Gumboro disease virus, suggested that rChIFN-α did not affect the chickens' immune response. interferon gumboro gà rchifn-α Biotechnology Hồ Quảng Đồ verfasserin aut Nguyễn Đăng Quân verfasserin aut In Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ HO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCE, 2021 15(2020), 1, Seite 5-15 (DE-627)DOAJ078618703 27349594 nnns volume:15 year:2020 number:1 pages:5-15 https://doi.org/10.46223/HCMCOUJS.tech.vi.15.1.1017.2020 kostenfrei https://doaj.org/article/321d56aae3e34b2c9344f7eec6a4aa04 kostenfrei https://journalofscience.ou.edu.vn/index.php/tech-vi/article/view/1017 kostenfrei https://doaj.org/toc/2734-9322 Journal toc kostenfrei https://doaj.org/toc/2734-9594 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 15 2020 1 5-15 |
| allfieldsGer |
10.46223/HCMCOUJS.tech.vi.15.1.1017.2020 doi (DE-627)DOAJ011412178 (DE-599)DOAJ321d56aae3e34b2c9344f7eec6a4aa04 DE-627 ger DE-627 rakwb eng TP248.13-248.65 Nguyễn Thị Thanh Giang verfasserin aut The ability inhibition Gumboro disease virus in 3-week-old chickens of chicken Interferon Alpha 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Virus-infectious diseases are permanent threats and cause serious lost for chicken industry of our country. Recombinant chicken interferon alpha (rChIFN-α) were expressed successfully on yeast pichia pastorisand was functional antivirus. The objective of this study was determined recombinant chicken interferon alpha (rChIFN-α) effectiveness in 3-week-old chickens infected infectious bursal diseasevirus (IBDV).In the present study, we used 3-week-old chickens without IBDV antibodies. Each 3-week-old chickens were infected virulent Gumboro disease virus with dose of 5x104ELD50. After 24 hours infected virus, they were exposed to eye/nasal drops with one of doses 0.1 μg/chick; 1 μg/chick; 10 μg/chick or 100 μg/chick. The results suggested treatment with rChIFN-α 0.1 μg/chick, the chickens' protected and survival rate were 46.7% and 80% respectively. Group of chickens were treated rChIFN-α 1 μg / chick, the protected and survival rate of chickens respectively 60.0% and 86.7%; The same result with chickens were treated rChIFN-α 10 μg/chick and 100 μg/chick, the chickens' protected and survival rate were 66.7% and 93.3%, respectively. Meanwhile, the positive control group (chicken infected virus, untreated), unprotected chickens (infection rate was 100%) and survival rate was only 60,00%. The negative control (chickens uninfected viruses, untreated with rChIFN-α), completely uninfected and 100% survival chickens. The result suggested that rChIFN-α have effective treating Gumboro disease and depends on the dose used. In addition, the chickens' antibody titres shown that the chickens' immune response in rChIFN-α groups was not different than the chickens infected only Gumboro disease virus, suggested that rChIFN-α did not affect the chickens' immune response. interferon gumboro gà rchifn-α Biotechnology Hồ Quảng Đồ verfasserin aut Nguyễn Đăng Quân verfasserin aut In Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ HO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCE, 2021 15(2020), 1, Seite 5-15 (DE-627)DOAJ078618703 27349594 nnns volume:15 year:2020 number:1 pages:5-15 https://doi.org/10.46223/HCMCOUJS.tech.vi.15.1.1017.2020 kostenfrei https://doaj.org/article/321d56aae3e34b2c9344f7eec6a4aa04 kostenfrei https://journalofscience.ou.edu.vn/index.php/tech-vi/article/view/1017 kostenfrei https://doaj.org/toc/2734-9322 Journal toc kostenfrei https://doaj.org/toc/2734-9594 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 15 2020 1 5-15 |
| allfieldsSound |
10.46223/HCMCOUJS.tech.vi.15.1.1017.2020 doi (DE-627)DOAJ011412178 (DE-599)DOAJ321d56aae3e34b2c9344f7eec6a4aa04 DE-627 ger DE-627 rakwb eng TP248.13-248.65 Nguyễn Thị Thanh Giang verfasserin aut The ability inhibition Gumboro disease virus in 3-week-old chickens of chicken Interferon Alpha 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Virus-infectious diseases are permanent threats and cause serious lost for chicken industry of our country. Recombinant chicken interferon alpha (rChIFN-α) were expressed successfully on yeast pichia pastorisand was functional antivirus. The objective of this study was determined recombinant chicken interferon alpha (rChIFN-α) effectiveness in 3-week-old chickens infected infectious bursal diseasevirus (IBDV).In the present study, we used 3-week-old chickens without IBDV antibodies. Each 3-week-old chickens were infected virulent Gumboro disease virus with dose of 5x104ELD50. After 24 hours infected virus, they were exposed to eye/nasal drops with one of doses 0.1 μg/chick; 1 μg/chick; 10 μg/chick or 100 μg/chick. The results suggested treatment with rChIFN-α 0.1 μg/chick, the chickens' protected and survival rate were 46.7% and 80% respectively. Group of chickens were treated rChIFN-α 1 μg / chick, the protected and survival rate of chickens respectively 60.0% and 86.7%; The same result with chickens were treated rChIFN-α 10 μg/chick and 100 μg/chick, the chickens' protected and survival rate were 66.7% and 93.3%, respectively. Meanwhile, the positive control group (chicken infected virus, untreated), unprotected chickens (infection rate was 100%) and survival rate was only 60,00%. The negative control (chickens uninfected viruses, untreated with rChIFN-α), completely uninfected and 100% survival chickens. The result suggested that rChIFN-α have effective treating Gumboro disease and depends on the dose used. In addition, the chickens' antibody titres shown that the chickens' immune response in rChIFN-α groups was not different than the chickens infected only Gumboro disease virus, suggested that rChIFN-α did not affect the chickens' immune response. interferon gumboro gà rchifn-α Biotechnology Hồ Quảng Đồ verfasserin aut Nguyễn Đăng Quân verfasserin aut In Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ HO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCE, 2021 15(2020), 1, Seite 5-15 (DE-627)DOAJ078618703 27349594 nnns volume:15 year:2020 number:1 pages:5-15 https://doi.org/10.46223/HCMCOUJS.tech.vi.15.1.1017.2020 kostenfrei https://doaj.org/article/321d56aae3e34b2c9344f7eec6a4aa04 kostenfrei https://journalofscience.ou.edu.vn/index.php/tech-vi/article/view/1017 kostenfrei https://doaj.org/toc/2734-9322 Journal toc kostenfrei https://doaj.org/toc/2734-9594 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 15 2020 1 5-15 |
| language |
English |
| source |
In Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ 15(2020), 1, Seite 5-15 volume:15 year:2020 number:1 pages:5-15 |
| sourceStr |
In Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ 15(2020), 1, Seite 5-15 volume:15 year:2020 number:1 pages:5-15 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| topic_facet |
interferon gumboro gà rchifn-α Biotechnology |
| isfreeaccess_bool |
true |
| container_title |
Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ |
| authorswithroles_txt_mv |
Nguyễn Thị Thanh Giang @@aut@@ Hồ Quảng Đồ @@aut@@ Nguyễn Đăng Quân @@aut@@ |
| publishDateDaySort_date |
2020-01-01T00:00:00Z |
| hierarchy_top_id |
DOAJ078618703 |
| id |
DOAJ011412178 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ011412178</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230310034148.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230225s2020 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.46223/HCMCOUJS.tech.vi.15.1.1017.2020</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ011412178</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ321d56aae3e34b2c9344f7eec6a4aa04</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">TP248.13-248.65</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Nguyễn Thị Thanh Giang</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="4"><subfield code="a">The ability inhibition Gumboro disease virus in 3-week-old chickens of chicken Interferon Alpha</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2020</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Virus-infectious diseases are permanent threats and cause serious lost for chicken industry of our country. Recombinant chicken interferon alpha (rChIFN-α) were expressed successfully on yeast pichia pastorisand was functional antivirus. The objective of this study was determined recombinant chicken interferon alpha (rChIFN-α) effectiveness in 3-week-old chickens infected infectious bursal diseasevirus (IBDV).In the present study, we used 3-week-old chickens without IBDV antibodies. Each 3-week-old chickens were infected virulent Gumboro disease virus with dose of 5x104ELD50. After 24 hours infected virus, they were exposed to eye/nasal drops with one of doses 0.1 μg/chick; 1 μg/chick; 10 μg/chick or 100 μg/chick. The results suggested treatment with rChIFN-α 0.1 μg/chick, the chickens' protected and survival rate were 46.7% and 80% respectively. Group of chickens were treated rChIFN-α 1 μg / chick, the protected and survival rate of chickens respectively 60.0% and 86.7%; The same result with chickens were treated rChIFN-α 10 μg/chick and 100 μg/chick, the chickens' protected and survival rate were 66.7% and 93.3%, respectively. Meanwhile, the positive control group (chicken infected virus, untreated), unprotected chickens (infection rate was 100%) and survival rate was only 60,00%. The negative control (chickens uninfected viruses, untreated with rChIFN-α), completely uninfected and 100% survival chickens. The result suggested that rChIFN-α have effective treating Gumboro disease and depends on the dose used. In addition, the chickens' antibody titres shown that the chickens' immune response in rChIFN-α groups was not different than the chickens infected only Gumboro disease virus, suggested that rChIFN-α did not affect the chickens' immune response.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">interferon</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">gumboro</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">gà</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">rchifn-α</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Biotechnology</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Hồ Quảng Đồ</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Nguyễn Đăng Quân</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ</subfield><subfield code="d">HO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCE, 2021</subfield><subfield code="g">15(2020), 1, Seite 5-15</subfield><subfield code="w">(DE-627)DOAJ078618703</subfield><subfield code="x">27349594</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:15</subfield><subfield code="g">year:2020</subfield><subfield code="g">number:1</subfield><subfield code="g">pages:5-15</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.46223/HCMCOUJS.tech.vi.15.1.1017.2020</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/321d56aae3e34b2c9344f7eec6a4aa04</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://journalofscience.ou.edu.vn/index.php/tech-vi/article/view/1017</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/2734-9322</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/2734-9594</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">15</subfield><subfield code="j">2020</subfield><subfield code="e">1</subfield><subfield code="h">5-15</subfield></datafield></record></collection>
|
| callnumber-first |
T - Technology |
| author |
Nguyễn Thị Thanh Giang |
| spellingShingle |
Nguyễn Thị Thanh Giang misc TP248.13-248.65 misc interferon misc gumboro misc gà misc rchifn-α misc Biotechnology The ability inhibition Gumboro disease virus in 3-week-old chickens of chicken Interferon Alpha |
| authorStr |
Nguyễn Thị Thanh Giang |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)DOAJ078618703 |
| format |
electronic Article |
| delete_txt_mv |
keep |
| author_role |
aut aut aut |
| collection |
DOAJ |
| remote_str |
true |
| callnumber-label |
TP248 |
| illustrated |
Not Illustrated |
| issn |
27349594 |
| topic_title |
TP248.13-248.65 The ability inhibition Gumboro disease virus in 3-week-old chickens of chicken Interferon Alpha interferon gumboro gà rchifn-α |
| topic |
misc TP248.13-248.65 misc interferon misc gumboro misc gà misc rchifn-α misc Biotechnology |
| topic_unstemmed |
misc TP248.13-248.65 misc interferon misc gumboro misc gà misc rchifn-α misc Biotechnology |
| topic_browse |
misc TP248.13-248.65 misc interferon misc gumboro misc gà misc rchifn-α misc Biotechnology |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
cr |
| hierarchy_parent_title |
Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ |
| hierarchy_parent_id |
DOAJ078618703 |
| hierarchy_top_title |
Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ |
| isfreeaccess_txt |
true |
| familylinks_str_mv |
(DE-627)DOAJ078618703 |
| title |
The ability inhibition Gumboro disease virus in 3-week-old chickens of chicken Interferon Alpha |
| ctrlnum |
(DE-627)DOAJ011412178 (DE-599)DOAJ321d56aae3e34b2c9344f7eec6a4aa04 |
| title_full |
The ability inhibition Gumboro disease virus in 3-week-old chickens of chicken Interferon Alpha |
| author_sort |
Nguyễn Thị Thanh Giang |
| journal |
Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ |
| journalStr |
Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ |
| callnumber-first-code |
T |
| lang_code |
eng |
| isOA_bool |
true |
| recordtype |
marc |
| publishDateSort |
2020 |
| contenttype_str_mv |
txt |
| container_start_page |
5 |
| author_browse |
Nguyễn Thị Thanh Giang Hồ Quảng Đồ Nguyễn Đăng Quân |
| container_volume |
15 |
| class |
TP248.13-248.65 |
| format_se |
Elektronische Aufsätze |
| author-letter |
Nguyễn Thị Thanh Giang |
| doi_str_mv |
10.46223/HCMCOUJS.tech.vi.15.1.1017.2020 |
| author2-role |
verfasserin |
| title_sort |
ability inhibition gumboro disease virus in 3-week-old chickens of chicken interferon alpha |
| callnumber |
TP248.13-248.65 |
| title_auth |
The ability inhibition Gumboro disease virus in 3-week-old chickens of chicken Interferon Alpha |
| abstract |
Virus-infectious diseases are permanent threats and cause serious lost for chicken industry of our country. Recombinant chicken interferon alpha (rChIFN-α) were expressed successfully on yeast pichia pastorisand was functional antivirus. The objective of this study was determined recombinant chicken interferon alpha (rChIFN-α) effectiveness in 3-week-old chickens infected infectious bursal diseasevirus (IBDV).In the present study, we used 3-week-old chickens without IBDV antibodies. Each 3-week-old chickens were infected virulent Gumboro disease virus with dose of 5x104ELD50. After 24 hours infected virus, they were exposed to eye/nasal drops with one of doses 0.1 μg/chick; 1 μg/chick; 10 μg/chick or 100 μg/chick. The results suggested treatment with rChIFN-α 0.1 μg/chick, the chickens' protected and survival rate were 46.7% and 80% respectively. Group of chickens were treated rChIFN-α 1 μg / chick, the protected and survival rate of chickens respectively 60.0% and 86.7%; The same result with chickens were treated rChIFN-α 10 μg/chick and 100 μg/chick, the chickens' protected and survival rate were 66.7% and 93.3%, respectively. Meanwhile, the positive control group (chicken infected virus, untreated), unprotected chickens (infection rate was 100%) and survival rate was only 60,00%. The negative control (chickens uninfected viruses, untreated with rChIFN-α), completely uninfected and 100% survival chickens. The result suggested that rChIFN-α have effective treating Gumboro disease and depends on the dose used. In addition, the chickens' antibody titres shown that the chickens' immune response in rChIFN-α groups was not different than the chickens infected only Gumboro disease virus, suggested that rChIFN-α did not affect the chickens' immune response. |
| abstractGer |
Virus-infectious diseases are permanent threats and cause serious lost for chicken industry of our country. Recombinant chicken interferon alpha (rChIFN-α) were expressed successfully on yeast pichia pastorisand was functional antivirus. The objective of this study was determined recombinant chicken interferon alpha (rChIFN-α) effectiveness in 3-week-old chickens infected infectious bursal diseasevirus (IBDV).In the present study, we used 3-week-old chickens without IBDV antibodies. Each 3-week-old chickens were infected virulent Gumboro disease virus with dose of 5x104ELD50. After 24 hours infected virus, they were exposed to eye/nasal drops with one of doses 0.1 μg/chick; 1 μg/chick; 10 μg/chick or 100 μg/chick. The results suggested treatment with rChIFN-α 0.1 μg/chick, the chickens' protected and survival rate were 46.7% and 80% respectively. Group of chickens were treated rChIFN-α 1 μg / chick, the protected and survival rate of chickens respectively 60.0% and 86.7%; The same result with chickens were treated rChIFN-α 10 μg/chick and 100 μg/chick, the chickens' protected and survival rate were 66.7% and 93.3%, respectively. Meanwhile, the positive control group (chicken infected virus, untreated), unprotected chickens (infection rate was 100%) and survival rate was only 60,00%. The negative control (chickens uninfected viruses, untreated with rChIFN-α), completely uninfected and 100% survival chickens. The result suggested that rChIFN-α have effective treating Gumboro disease and depends on the dose used. In addition, the chickens' antibody titres shown that the chickens' immune response in rChIFN-α groups was not different than the chickens infected only Gumboro disease virus, suggested that rChIFN-α did not affect the chickens' immune response. |
| abstract_unstemmed |
Virus-infectious diseases are permanent threats and cause serious lost for chicken industry of our country. Recombinant chicken interferon alpha (rChIFN-α) were expressed successfully on yeast pichia pastorisand was functional antivirus. The objective of this study was determined recombinant chicken interferon alpha (rChIFN-α) effectiveness in 3-week-old chickens infected infectious bursal diseasevirus (IBDV).In the present study, we used 3-week-old chickens without IBDV antibodies. Each 3-week-old chickens were infected virulent Gumboro disease virus with dose of 5x104ELD50. After 24 hours infected virus, they were exposed to eye/nasal drops with one of doses 0.1 μg/chick; 1 μg/chick; 10 μg/chick or 100 μg/chick. The results suggested treatment with rChIFN-α 0.1 μg/chick, the chickens' protected and survival rate were 46.7% and 80% respectively. Group of chickens were treated rChIFN-α 1 μg / chick, the protected and survival rate of chickens respectively 60.0% and 86.7%; The same result with chickens were treated rChIFN-α 10 μg/chick and 100 μg/chick, the chickens' protected and survival rate were 66.7% and 93.3%, respectively. Meanwhile, the positive control group (chicken infected virus, untreated), unprotected chickens (infection rate was 100%) and survival rate was only 60,00%. The negative control (chickens uninfected viruses, untreated with rChIFN-α), completely uninfected and 100% survival chickens. The result suggested that rChIFN-α have effective treating Gumboro disease and depends on the dose used. In addition, the chickens' antibody titres shown that the chickens' immune response in rChIFN-α groups was not different than the chickens infected only Gumboro disease virus, suggested that rChIFN-α did not affect the chickens' immune response. |
| collection_details |
GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ |
| container_issue |
1 |
| title_short |
The ability inhibition Gumboro disease virus in 3-week-old chickens of chicken Interferon Alpha |
| url |
https://doi.org/10.46223/HCMCOUJS.tech.vi.15.1.1017.2020 https://doaj.org/article/321d56aae3e34b2c9344f7eec6a4aa04 https://journalofscience.ou.edu.vn/index.php/tech-vi/article/view/1017 https://doaj.org/toc/2734-9322 https://doaj.org/toc/2734-9594 |
| remote_bool |
true |
| author2 |
Hồ Quảng Đồ Nguyễn Đăng Quân |
| author2Str |
Hồ Quảng Đồ Nguyễn Đăng Quân |
| ppnlink |
DOAJ078618703 |
| callnumber-subject |
TP - Chemical Technology |
| mediatype_str_mv |
c |
| isOA_txt |
true |
| hochschulschrift_bool |
false |
| doi_str |
10.46223/HCMCOUJS.tech.vi.15.1.1017.2020 |
| callnumber-a |
TP248.13-248.65 |
| up_date |
2024-07-03T20:11:30.072Z |
| _version_ |
1803590031191834624 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ011412178</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230310034148.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230225s2020 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.46223/HCMCOUJS.tech.vi.15.1.1017.2020</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ011412178</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ321d56aae3e34b2c9344f7eec6a4aa04</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">TP248.13-248.65</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Nguyễn Thị Thanh Giang</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="4"><subfield code="a">The ability inhibition Gumboro disease virus in 3-week-old chickens of chicken Interferon Alpha</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2020</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Virus-infectious diseases are permanent threats and cause serious lost for chicken industry of our country. Recombinant chicken interferon alpha (rChIFN-α) were expressed successfully on yeast pichia pastorisand was functional antivirus. The objective of this study was determined recombinant chicken interferon alpha (rChIFN-α) effectiveness in 3-week-old chickens infected infectious bursal diseasevirus (IBDV).In the present study, we used 3-week-old chickens without IBDV antibodies. Each 3-week-old chickens were infected virulent Gumboro disease virus with dose of 5x104ELD50. After 24 hours infected virus, they were exposed to eye/nasal drops with one of doses 0.1 μg/chick; 1 μg/chick; 10 μg/chick or 100 μg/chick. The results suggested treatment with rChIFN-α 0.1 μg/chick, the chickens' protected and survival rate were 46.7% and 80% respectively. Group of chickens were treated rChIFN-α 1 μg / chick, the protected and survival rate of chickens respectively 60.0% and 86.7%; The same result with chickens were treated rChIFN-α 10 μg/chick and 100 μg/chick, the chickens' protected and survival rate were 66.7% and 93.3%, respectively. Meanwhile, the positive control group (chicken infected virus, untreated), unprotected chickens (infection rate was 100%) and survival rate was only 60,00%. The negative control (chickens uninfected viruses, untreated with rChIFN-α), completely uninfected and 100% survival chickens. The result suggested that rChIFN-α have effective treating Gumboro disease and depends on the dose used. In addition, the chickens' antibody titres shown that the chickens' immune response in rChIFN-α groups was not different than the chickens infected only Gumboro disease virus, suggested that rChIFN-α did not affect the chickens' immune response.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">interferon</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">gumboro</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">gà</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">rchifn-α</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Biotechnology</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Hồ Quảng Đồ</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Nguyễn Đăng Quân</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ</subfield><subfield code="d">HO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCE, 2021</subfield><subfield code="g">15(2020), 1, Seite 5-15</subfield><subfield code="w">(DE-627)DOAJ078618703</subfield><subfield code="x">27349594</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:15</subfield><subfield code="g">year:2020</subfield><subfield code="g">number:1</subfield><subfield code="g">pages:5-15</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.46223/HCMCOUJS.tech.vi.15.1.1017.2020</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/321d56aae3e34b2c9344f7eec6a4aa04</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://journalofscience.ou.edu.vn/index.php/tech-vi/article/view/1017</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/2734-9322</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/2734-9594</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">15</subfield><subfield code="j">2020</subfield><subfield code="e">1</subfield><subfield code="h">5-15</subfield></datafield></record></collection>
|
| score |
7.3970747 |