A Gene Expression Regulator: miRNA

MicroRNAs (miRNA) binding to target mRNAs and having function in regulating gene expression are of 18-25 nucleotides in length and take place in the class of non-coding RNAs. Although aproximately 1900 human miRNA types have been identified so far, quite little is known about their biological functi...
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Autor*in:	Figen Guzelgul [verfasserIn] Kiymet Aksoy [verfasserIn]

Format:	E-Artikel
Sprache:	Türkisch

Erschienen:	2015

Schlagwörter:	Noncoding RNA miRNA mRNA

Übergeordnetes Werk:	In: Arsiv Kaynak Tarama Dergisi - Cukurova University Faculty of Medicine, 2013, 24(2015), 4, Seite 472-493
Übergeordnetes Werk:	volume:24 ; year:2015 ; number:4 ; pages:472-493

Links:	Link aufrufen Link aufrufen Journal toc

Katalog-ID:	DOAJ012057649

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spelling	(DE-627)DOAJ012057649 (DE-599)DOAJe548115edf264142a8b4764aa89dabf2 DE-627 ger DE-627 rakwb tur R5-920 Figen Guzelgul verfasserin aut A Gene Expression Regulator: miRNA 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier MicroRNAs (miRNA) binding to target mRNAs and having function in regulating gene expression are of 18-25 nucleotides in length and take place in the class of non-coding RNAs. Although aproximately 1900 human miRNA types have been identified so far, quite little is known about their biological functions. In some studies, it is shown that miRNA expression levels are important for many biological functions such as cell proliferation, differentiation, apoptosis and metabolism. Recent studies have pointed out that miRNAs have been used as diagnosis and prognosis biomarker in many human diseases including cancer, viral diseases, cardiovascular disorders and metabolic distrubance. Such as a miRNA type's regulating more than one mRNA expression levels, a mRNA level has been regulated by numbers of miRNA types. Since changing the expression level of a miRNA type effects the whole metabolism, it is required to have cell-specific miRNAs. In the event of cell type- specific miRNAs are having found, it is expected that the general metabolism is better understood and, moreover, miRNAs are used more effectively in diagnosis and treatment of diseases. [Archives Medical Review Journal 2015; 24(4.000): 472-493] Noncoding RNA miRNA mRNA Medicine R Medicine (General) Kiymet Aksoy verfasserin aut In Arsiv Kaynak Tarama Dergisi Cukurova University Faculty of Medicine, 2013 24(2015), 4, Seite 472-493 (DE-627)749504455 (DE-600)2719557-0 13003755 nnns volume:24 year:2015 number:4 pages:472-493 https://doaj.org/article/e548115edf264142a8b4764aa89dabf2 kostenfrei http://www.scopemed.org/fulltextpdf.php?mno=181455 kostenfrei https://doaj.org/toc/1300-3755 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 24 2015 4 472-493
allfields_unstemmed	(DE-627)DOAJ012057649 (DE-599)DOAJe548115edf264142a8b4764aa89dabf2 DE-627 ger DE-627 rakwb tur R5-920 Figen Guzelgul verfasserin aut A Gene Expression Regulator: miRNA 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier MicroRNAs (miRNA) binding to target mRNAs and having function in regulating gene expression are of 18-25 nucleotides in length and take place in the class of non-coding RNAs. Although aproximately 1900 human miRNA types have been identified so far, quite little is known about their biological functions. In some studies, it is shown that miRNA expression levels are important for many biological functions such as cell proliferation, differentiation, apoptosis and metabolism. Recent studies have pointed out that miRNAs have been used as diagnosis and prognosis biomarker in many human diseases including cancer, viral diseases, cardiovascular disorders and metabolic distrubance. Such as a miRNA type's regulating more than one mRNA expression levels, a mRNA level has been regulated by numbers of miRNA types. Since changing the expression level of a miRNA type effects the whole metabolism, it is required to have cell-specific miRNAs. In the event of cell type- specific miRNAs are having found, it is expected that the general metabolism is better understood and, moreover, miRNAs are used more effectively in diagnosis and treatment of diseases. [Archives Medical Review Journal 2015; 24(4.000): 472-493] Noncoding RNA miRNA mRNA Medicine R Medicine (General) Kiymet Aksoy verfasserin aut In Arsiv Kaynak Tarama Dergisi Cukurova University Faculty of Medicine, 2013 24(2015), 4, Seite 472-493 (DE-627)749504455 (DE-600)2719557-0 13003755 nnns volume:24 year:2015 number:4 pages:472-493 https://doaj.org/article/e548115edf264142a8b4764aa89dabf2 kostenfrei http://www.scopemed.org/fulltextpdf.php?mno=181455 kostenfrei https://doaj.org/toc/1300-3755 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 24 2015 4 472-493
allfieldsGer	(DE-627)DOAJ012057649 (DE-599)DOAJe548115edf264142a8b4764aa89dabf2 DE-627 ger DE-627 rakwb tur R5-920 Figen Guzelgul verfasserin aut A Gene Expression Regulator: miRNA 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier MicroRNAs (miRNA) binding to target mRNAs and having function in regulating gene expression are of 18-25 nucleotides in length and take place in the class of non-coding RNAs. Although aproximately 1900 human miRNA types have been identified so far, quite little is known about their biological functions. In some studies, it is shown that miRNA expression levels are important for many biological functions such as cell proliferation, differentiation, apoptosis and metabolism. Recent studies have pointed out that miRNAs have been used as diagnosis and prognosis biomarker in many human diseases including cancer, viral diseases, cardiovascular disorders and metabolic distrubance. Such as a miRNA type's regulating more than one mRNA expression levels, a mRNA level has been regulated by numbers of miRNA types. Since changing the expression level of a miRNA type effects the whole metabolism, it is required to have cell-specific miRNAs. In the event of cell type- specific miRNAs are having found, it is expected that the general metabolism is better understood and, moreover, miRNAs are used more effectively in diagnosis and treatment of diseases. [Archives Medical Review Journal 2015; 24(4.000): 472-493] Noncoding RNA miRNA mRNA Medicine R Medicine (General) Kiymet Aksoy verfasserin aut In Arsiv Kaynak Tarama Dergisi Cukurova University Faculty of Medicine, 2013 24(2015), 4, Seite 472-493 (DE-627)749504455 (DE-600)2719557-0 13003755 nnns volume:24 year:2015 number:4 pages:472-493 https://doaj.org/article/e548115edf264142a8b4764aa89dabf2 kostenfrei http://www.scopemed.org/fulltextpdf.php?mno=181455 kostenfrei https://doaj.org/toc/1300-3755 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 24 2015 4 472-493
allfieldsSound	(DE-627)DOAJ012057649 (DE-599)DOAJe548115edf264142a8b4764aa89dabf2 DE-627 ger DE-627 rakwb tur R5-920 Figen Guzelgul verfasserin aut A Gene Expression Regulator: miRNA 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier MicroRNAs (miRNA) binding to target mRNAs and having function in regulating gene expression are of 18-25 nucleotides in length and take place in the class of non-coding RNAs. Although aproximately 1900 human miRNA types have been identified so far, quite little is known about their biological functions. In some studies, it is shown that miRNA expression levels are important for many biological functions such as cell proliferation, differentiation, apoptosis and metabolism. Recent studies have pointed out that miRNAs have been used as diagnosis and prognosis biomarker in many human diseases including cancer, viral diseases, cardiovascular disorders and metabolic distrubance. Such as a miRNA type's regulating more than one mRNA expression levels, a mRNA level has been regulated by numbers of miRNA types. Since changing the expression level of a miRNA type effects the whole metabolism, it is required to have cell-specific miRNAs. In the event of cell type- specific miRNAs are having found, it is expected that the general metabolism is better understood and, moreover, miRNAs are used more effectively in diagnosis and treatment of diseases. [Archives Medical Review Journal 2015; 24(4.000): 472-493] Noncoding RNA miRNA mRNA Medicine R Medicine (General) Kiymet Aksoy verfasserin aut In Arsiv Kaynak Tarama Dergisi Cukurova University Faculty of Medicine, 2013 24(2015), 4, Seite 472-493 (DE-627)749504455 (DE-600)2719557-0 13003755 nnns volume:24 year:2015 number:4 pages:472-493 https://doaj.org/article/e548115edf264142a8b4764aa89dabf2 kostenfrei http://www.scopemed.org/fulltextpdf.php?mno=181455 kostenfrei https://doaj.org/toc/1300-3755 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 24 2015 4 472-493
language	Turkish
source	In Arsiv Kaynak Tarama Dergisi 24(2015), 4, Seite 472-493 volume:24 year:2015 number:4 pages:472-493
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callnumber-first	R - Medicine
author	Figen Guzelgul
spellingShingle	Figen Guzelgul misc R5-920 misc Noncoding RNA misc miRNA misc mRNA misc Medicine misc R misc Medicine (General) A Gene Expression Regulator: miRNA
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topic_title	R5-920 A Gene Expression Regulator: miRNA Noncoding RNA miRNA mRNA
topic	misc R5-920 misc Noncoding RNA misc miRNA misc mRNA misc Medicine misc R misc Medicine (General)
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title	A Gene Expression Regulator: miRNA
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title_full	A Gene Expression Regulator: miRNA
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title_sort	gene expression regulator: mirna
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title_auth	A Gene Expression Regulator: miRNA
abstract	MicroRNAs (miRNA) binding to target mRNAs and having function in regulating gene expression are of 18-25 nucleotides in length and take place in the class of non-coding RNAs. Although aproximately 1900 human miRNA types have been identified so far, quite little is known about their biological functions. In some studies, it is shown that miRNA expression levels are important for many biological functions such as cell proliferation, differentiation, apoptosis and metabolism. Recent studies have pointed out that miRNAs have been used as diagnosis and prognosis biomarker in many human diseases including cancer, viral diseases, cardiovascular disorders and metabolic distrubance. Such as a miRNA type's regulating more than one mRNA expression levels, a mRNA level has been regulated by numbers of miRNA types. Since changing the expression level of a miRNA type effects the whole metabolism, it is required to have cell-specific miRNAs. In the event of cell type- specific miRNAs are having found, it is expected that the general metabolism is better understood and, moreover, miRNAs are used more effectively in diagnosis and treatment of diseases. [Archives Medical Review Journal 2015; 24(4.000): 472-493]
abstractGer	MicroRNAs (miRNA) binding to target mRNAs and having function in regulating gene expression are of 18-25 nucleotides in length and take place in the class of non-coding RNAs. Although aproximately 1900 human miRNA types have been identified so far, quite little is known about their biological functions. In some studies, it is shown that miRNA expression levels are important for many biological functions such as cell proliferation, differentiation, apoptosis and metabolism. Recent studies have pointed out that miRNAs have been used as diagnosis and prognosis biomarker in many human diseases including cancer, viral diseases, cardiovascular disorders and metabolic distrubance. Such as a miRNA type's regulating more than one mRNA expression levels, a mRNA level has been regulated by numbers of miRNA types. Since changing the expression level of a miRNA type effects the whole metabolism, it is required to have cell-specific miRNAs. In the event of cell type- specific miRNAs are having found, it is expected that the general metabolism is better understood and, moreover, miRNAs are used more effectively in diagnosis and treatment of diseases. [Archives Medical Review Journal 2015; 24(4.000): 472-493]
abstract_unstemmed	MicroRNAs (miRNA) binding to target mRNAs and having function in regulating gene expression are of 18-25 nucleotides in length and take place in the class of non-coding RNAs. Although aproximately 1900 human miRNA types have been identified so far, quite little is known about their biological functions. In some studies, it is shown that miRNA expression levels are important for many biological functions such as cell proliferation, differentiation, apoptosis and metabolism. Recent studies have pointed out that miRNAs have been used as diagnosis and prognosis biomarker in many human diseases including cancer, viral diseases, cardiovascular disorders and metabolic distrubance. Such as a miRNA type's regulating more than one mRNA expression levels, a mRNA level has been regulated by numbers of miRNA types. Since changing the expression level of a miRNA type effects the whole metabolism, it is required to have cell-specific miRNAs. In the event of cell type- specific miRNAs are having found, it is expected that the general metabolism is better understood and, moreover, miRNAs are used more effectively in diagnosis and treatment of diseases. [Archives Medical Review Journal 2015; 24(4.000): 472-493]
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