Conicity index as a contributor marker of inflammation in haemodialysis patients

Introduction: Abdominal fat mass is an important risk factor of inflammation in the general population as it is in haemodialysis (HD) patients. The aim of this study was to investigate the association of adiposity using the conicity index (Ci) with nutritional-inflammatory markers and to analyse whe...
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Autor*in:	Mar Ruperto [verfasserIn] Guillermina Barril [verfasserIn] Francisco J. Sánchez-Muniz [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch ; Spanisch

Erschienen:	2013

Schlagwörter:	Índice de conicidad Grasa abdominal Inflamación Malnutrición-inflamación Hemodiálisis

Übergeordnetes Werk:	In: Nutrición Hospitalaria - Arán Ediciones, S. L., 2019, 28(2013), 5, Seite 1688-1695
Übergeordnetes Werk:	volume:28 ; year:2013 ; number:5 ; pages:1688-1695

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3305/nh.2013.28.5.6626

Katalog-ID:	DOAJ012442887

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520			\|a Introduction: Abdominal fat mass is an important risk factor of inflammation in the general population as it is in haemodialysis (HD) patients. The aim of this study was to investigate the association of adiposity using the conicity index (Ci) with nutritional-inflammatory markers and to analyse whether these factors were related with the clinical outcome in HD patients. Methods: A cross-sectional study in 80 HD patients (men, 65%; aged 68.2 ± 14.2) was carried out. Abdominal fat deposition was evaluated by Ci median with regard to baseline inflammatory, anthropomorphic, and nutritional markers. Linear regression analysis was applied to identify whether serum C-reactive protein (CRP), as an inflammatory biomarker, was an independent predictor of Ci in HD patients. Results: Mean Ci was significantly greater in men (p = 0.001). Significant positive correlations were observed between Ci and serum triglycerides (r = 0.23; p < 0.05) and Ln of serum CRP (r = 0.27; p < 0.01). A significantly higher median Ci (men ≥ 1.39 and women ≥ 1.33) was observed in inflammated overweight patients by multivariate analysis (p < 0.05). Serum CRP, as an inflammatory biomarker, was a significant predictor (p = 0.021) of Ci, but its predictive value disappeared after median Ci adjustment of linear regression analysis. Conclusion: Abdominal fat mass, measured by Ci, appears directly linked to inflammation in dialysis. Results support the hypothesis that inflammation in HD patients has pleiotropic effects depending on abdominal body adiposity.
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allfields	10.3305/nh.2013.28.5.6626 doi (DE-627)DOAJ012442887 (DE-599)DOAJa3ce59b3c96545a5841c9df0062857da DE-627 ger DE-627 rakwb eng spa RC620-627 Mar Ruperto verfasserin aut Conicity index as a contributor marker of inflammation in haemodialysis patients 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Abdominal fat mass is an important risk factor of inflammation in the general population as it is in haemodialysis (HD) patients. The aim of this study was to investigate the association of adiposity using the conicity index (Ci) with nutritional-inflammatory markers and to analyse whether these factors were related with the clinical outcome in HD patients. Methods: A cross-sectional study in 80 HD patients (men, 65%; aged 68.2 ± 14.2) was carried out. Abdominal fat deposition was evaluated by Ci median with regard to baseline inflammatory, anthropomorphic, and nutritional markers. Linear regression analysis was applied to identify whether serum C-reactive protein (CRP), as an inflammatory biomarker, was an independent predictor of Ci in HD patients. Results: Mean Ci was significantly greater in men (p = 0.001). Significant positive correlations were observed between Ci and serum triglycerides (r = 0.23; p < 0.05) and Ln of serum CRP (r = 0.27; p < 0.01). A significantly higher median Ci (men ≥ 1.39 and women ≥ 1.33) was observed in inflammated overweight patients by multivariate analysis (p < 0.05). Serum CRP, as an inflammatory biomarker, was a significant predictor (p = 0.021) of Ci, but its predictive value disappeared after median Ci adjustment of linear regression analysis. Conclusion: Abdominal fat mass, measured by Ci, appears directly linked to inflammation in dialysis. Results support the hypothesis that inflammation in HD patients has pleiotropic effects depending on abdominal body adiposity. Índice de conicidad Grasa abdominal Inflamación Malnutrición-inflamación Hemodiálisis Nutritional diseases. Deficiency diseases Guillermina Barril verfasserin aut Francisco J. Sánchez-Muniz verfasserin aut In Nutrición Hospitalaria Arán Ediciones, S. L., 2019 28(2013), 5, Seite 1688-1695 (DE-627)352107235 (DE-600)2084590-X 16995198 nnns volume:28 year:2013 number:5 pages:1688-1695 https://doi.org/10.3305/nh.2013.28.5.6626 kostenfrei https://doaj.org/article/a3ce59b3c96545a5841c9df0062857da kostenfrei http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112013000500047&lng=en&tlng=en kostenfrei https://doaj.org/toc/0212-1611 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 28 2013 5 1688-1695
spelling	10.3305/nh.2013.28.5.6626 doi (DE-627)DOAJ012442887 (DE-599)DOAJa3ce59b3c96545a5841c9df0062857da DE-627 ger DE-627 rakwb eng spa RC620-627 Mar Ruperto verfasserin aut Conicity index as a contributor marker of inflammation in haemodialysis patients 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Abdominal fat mass is an important risk factor of inflammation in the general population as it is in haemodialysis (HD) patients. The aim of this study was to investigate the association of adiposity using the conicity index (Ci) with nutritional-inflammatory markers and to analyse whether these factors were related with the clinical outcome in HD patients. Methods: A cross-sectional study in 80 HD patients (men, 65%; aged 68.2 ± 14.2) was carried out. Abdominal fat deposition was evaluated by Ci median with regard to baseline inflammatory, anthropomorphic, and nutritional markers. Linear regression analysis was applied to identify whether serum C-reactive protein (CRP), as an inflammatory biomarker, was an independent predictor of Ci in HD patients. Results: Mean Ci was significantly greater in men (p = 0.001). Significant positive correlations were observed between Ci and serum triglycerides (r = 0.23; p < 0.05) and Ln of serum CRP (r = 0.27; p < 0.01). A significantly higher median Ci (men ≥ 1.39 and women ≥ 1.33) was observed in inflammated overweight patients by multivariate analysis (p < 0.05). Serum CRP, as an inflammatory biomarker, was a significant predictor (p = 0.021) of Ci, but its predictive value disappeared after median Ci adjustment of linear regression analysis. Conclusion: Abdominal fat mass, measured by Ci, appears directly linked to inflammation in dialysis. Results support the hypothesis that inflammation in HD patients has pleiotropic effects depending on abdominal body adiposity. Índice de conicidad Grasa abdominal Inflamación Malnutrición-inflamación Hemodiálisis Nutritional diseases. Deficiency diseases Guillermina Barril verfasserin aut Francisco J. Sánchez-Muniz verfasserin aut In Nutrición Hospitalaria Arán Ediciones, S. L., 2019 28(2013), 5, Seite 1688-1695 (DE-627)352107235 (DE-600)2084590-X 16995198 nnns volume:28 year:2013 number:5 pages:1688-1695 https://doi.org/10.3305/nh.2013.28.5.6626 kostenfrei https://doaj.org/article/a3ce59b3c96545a5841c9df0062857da kostenfrei http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112013000500047&lng=en&tlng=en kostenfrei https://doaj.org/toc/0212-1611 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 28 2013 5 1688-1695
allfields_unstemmed	10.3305/nh.2013.28.5.6626 doi (DE-627)DOAJ012442887 (DE-599)DOAJa3ce59b3c96545a5841c9df0062857da DE-627 ger DE-627 rakwb eng spa RC620-627 Mar Ruperto verfasserin aut Conicity index as a contributor marker of inflammation in haemodialysis patients 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Abdominal fat mass is an important risk factor of inflammation in the general population as it is in haemodialysis (HD) patients. The aim of this study was to investigate the association of adiposity using the conicity index (Ci) with nutritional-inflammatory markers and to analyse whether these factors were related with the clinical outcome in HD patients. Methods: A cross-sectional study in 80 HD patients (men, 65%; aged 68.2 ± 14.2) was carried out. Abdominal fat deposition was evaluated by Ci median with regard to baseline inflammatory, anthropomorphic, and nutritional markers. Linear regression analysis was applied to identify whether serum C-reactive protein (CRP), as an inflammatory biomarker, was an independent predictor of Ci in HD patients. Results: Mean Ci was significantly greater in men (p = 0.001). Significant positive correlations were observed between Ci and serum triglycerides (r = 0.23; p < 0.05) and Ln of serum CRP (r = 0.27; p < 0.01). A significantly higher median Ci (men ≥ 1.39 and women ≥ 1.33) was observed in inflammated overweight patients by multivariate analysis (p < 0.05). Serum CRP, as an inflammatory biomarker, was a significant predictor (p = 0.021) of Ci, but its predictive value disappeared after median Ci adjustment of linear regression analysis. Conclusion: Abdominal fat mass, measured by Ci, appears directly linked to inflammation in dialysis. Results support the hypothesis that inflammation in HD patients has pleiotropic effects depending on abdominal body adiposity. Índice de conicidad Grasa abdominal Inflamación Malnutrición-inflamación Hemodiálisis Nutritional diseases. Deficiency diseases Guillermina Barril verfasserin aut Francisco J. Sánchez-Muniz verfasserin aut In Nutrición Hospitalaria Arán Ediciones, S. L., 2019 28(2013), 5, Seite 1688-1695 (DE-627)352107235 (DE-600)2084590-X 16995198 nnns volume:28 year:2013 number:5 pages:1688-1695 https://doi.org/10.3305/nh.2013.28.5.6626 kostenfrei https://doaj.org/article/a3ce59b3c96545a5841c9df0062857da kostenfrei http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112013000500047&lng=en&tlng=en kostenfrei https://doaj.org/toc/0212-1611 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 28 2013 5 1688-1695
allfieldsGer	10.3305/nh.2013.28.5.6626 doi (DE-627)DOAJ012442887 (DE-599)DOAJa3ce59b3c96545a5841c9df0062857da DE-627 ger DE-627 rakwb eng spa RC620-627 Mar Ruperto verfasserin aut Conicity index as a contributor marker of inflammation in haemodialysis patients 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Abdominal fat mass is an important risk factor of inflammation in the general population as it is in haemodialysis (HD) patients. The aim of this study was to investigate the association of adiposity using the conicity index (Ci) with nutritional-inflammatory markers and to analyse whether these factors were related with the clinical outcome in HD patients. Methods: A cross-sectional study in 80 HD patients (men, 65%; aged 68.2 ± 14.2) was carried out. Abdominal fat deposition was evaluated by Ci median with regard to baseline inflammatory, anthropomorphic, and nutritional markers. Linear regression analysis was applied to identify whether serum C-reactive protein (CRP), as an inflammatory biomarker, was an independent predictor of Ci in HD patients. Results: Mean Ci was significantly greater in men (p = 0.001). Significant positive correlations were observed between Ci and serum triglycerides (r = 0.23; p < 0.05) and Ln of serum CRP (r = 0.27; p < 0.01). A significantly higher median Ci (men ≥ 1.39 and women ≥ 1.33) was observed in inflammated overweight patients by multivariate analysis (p < 0.05). Serum CRP, as an inflammatory biomarker, was a significant predictor (p = 0.021) of Ci, but its predictive value disappeared after median Ci adjustment of linear regression analysis. Conclusion: Abdominal fat mass, measured by Ci, appears directly linked to inflammation in dialysis. Results support the hypothesis that inflammation in HD patients has pleiotropic effects depending on abdominal body adiposity. Índice de conicidad Grasa abdominal Inflamación Malnutrición-inflamación Hemodiálisis Nutritional diseases. Deficiency diseases Guillermina Barril verfasserin aut Francisco J. Sánchez-Muniz verfasserin aut In Nutrición Hospitalaria Arán Ediciones, S. L., 2019 28(2013), 5, Seite 1688-1695 (DE-627)352107235 (DE-600)2084590-X 16995198 nnns volume:28 year:2013 number:5 pages:1688-1695 https://doi.org/10.3305/nh.2013.28.5.6626 kostenfrei https://doaj.org/article/a3ce59b3c96545a5841c9df0062857da kostenfrei http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112013000500047&lng=en&tlng=en kostenfrei https://doaj.org/toc/0212-1611 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 28 2013 5 1688-1695
allfieldsSound	10.3305/nh.2013.28.5.6626 doi (DE-627)DOAJ012442887 (DE-599)DOAJa3ce59b3c96545a5841c9df0062857da DE-627 ger DE-627 rakwb eng spa RC620-627 Mar Ruperto verfasserin aut Conicity index as a contributor marker of inflammation in haemodialysis patients 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Abdominal fat mass is an important risk factor of inflammation in the general population as it is in haemodialysis (HD) patients. The aim of this study was to investigate the association of adiposity using the conicity index (Ci) with nutritional-inflammatory markers and to analyse whether these factors were related with the clinical outcome in HD patients. Methods: A cross-sectional study in 80 HD patients (men, 65%; aged 68.2 ± 14.2) was carried out. Abdominal fat deposition was evaluated by Ci median with regard to baseline inflammatory, anthropomorphic, and nutritional markers. Linear regression analysis was applied to identify whether serum C-reactive protein (CRP), as an inflammatory biomarker, was an independent predictor of Ci in HD patients. Results: Mean Ci was significantly greater in men (p = 0.001). Significant positive correlations were observed between Ci and serum triglycerides (r = 0.23; p < 0.05) and Ln of serum CRP (r = 0.27; p < 0.01). A significantly higher median Ci (men ≥ 1.39 and women ≥ 1.33) was observed in inflammated overweight patients by multivariate analysis (p < 0.05). Serum CRP, as an inflammatory biomarker, was a significant predictor (p = 0.021) of Ci, but its predictive value disappeared after median Ci adjustment of linear regression analysis. Conclusion: Abdominal fat mass, measured by Ci, appears directly linked to inflammation in dialysis. Results support the hypothesis that inflammation in HD patients has pleiotropic effects depending on abdominal body adiposity. Índice de conicidad Grasa abdominal Inflamación Malnutrición-inflamación Hemodiálisis Nutritional diseases. Deficiency diseases Guillermina Barril verfasserin aut Francisco J. Sánchez-Muniz verfasserin aut In Nutrición Hospitalaria Arán Ediciones, S. L., 2019 28(2013), 5, Seite 1688-1695 (DE-627)352107235 (DE-600)2084590-X 16995198 nnns volume:28 year:2013 number:5 pages:1688-1695 https://doi.org/10.3305/nh.2013.28.5.6626 kostenfrei https://doaj.org/article/a3ce59b3c96545a5841c9df0062857da kostenfrei http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112013000500047&lng=en&tlng=en kostenfrei https://doaj.org/toc/0212-1611 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 28 2013 5 1688-1695
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callnumber-first	R - Medicine
author	Mar Ruperto
spellingShingle	Mar Ruperto misc RC620-627 misc Índice de conicidad misc Grasa abdominal misc Inflamación misc Malnutrición-inflamación misc Hemodiálisis misc Nutritional diseases. Deficiency diseases Conicity index as a contributor marker of inflammation in haemodialysis patients
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topic_title	RC620-627 Conicity index as a contributor marker of inflammation in haemodialysis patients Índice de conicidad Grasa abdominal Inflamación Malnutrición-inflamación Hemodiálisis
topic	misc RC620-627 misc Índice de conicidad misc Grasa abdominal misc Inflamación misc Malnutrición-inflamación misc Hemodiálisis misc Nutritional diseases. Deficiency diseases
topic_unstemmed	misc RC620-627 misc Índice de conicidad misc Grasa abdominal misc Inflamación misc Malnutrición-inflamación misc Hemodiálisis misc Nutritional diseases. Deficiency diseases
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title	Conicity index as a contributor marker of inflammation in haemodialysis patients
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title_full	Conicity index as a contributor marker of inflammation in haemodialysis patients
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title_sort	conicity index as a contributor marker of inflammation in haemodialysis patients
callnumber	RC620-627
title_auth	Conicity index as a contributor marker of inflammation in haemodialysis patients
abstract	Introduction: Abdominal fat mass is an important risk factor of inflammation in the general population as it is in haemodialysis (HD) patients. The aim of this study was to investigate the association of adiposity using the conicity index (Ci) with nutritional-inflammatory markers and to analyse whether these factors were related with the clinical outcome in HD patients. Methods: A cross-sectional study in 80 HD patients (men, 65%; aged 68.2 ± 14.2) was carried out. Abdominal fat deposition was evaluated by Ci median with regard to baseline inflammatory, anthropomorphic, and nutritional markers. Linear regression analysis was applied to identify whether serum C-reactive protein (CRP), as an inflammatory biomarker, was an independent predictor of Ci in HD patients. Results: Mean Ci was significantly greater in men (p = 0.001). Significant positive correlations were observed between Ci and serum triglycerides (r = 0.23; p < 0.05) and Ln of serum CRP (r = 0.27; p < 0.01). A significantly higher median Ci (men ≥ 1.39 and women ≥ 1.33) was observed in inflammated overweight patients by multivariate analysis (p < 0.05). Serum CRP, as an inflammatory biomarker, was a significant predictor (p = 0.021) of Ci, but its predictive value disappeared after median Ci adjustment of linear regression analysis. Conclusion: Abdominal fat mass, measured by Ci, appears directly linked to inflammation in dialysis. Results support the hypothesis that inflammation in HD patients has pleiotropic effects depending on abdominal body adiposity.
abstractGer	Introduction: Abdominal fat mass is an important risk factor of inflammation in the general population as it is in haemodialysis (HD) patients. The aim of this study was to investigate the association of adiposity using the conicity index (Ci) with nutritional-inflammatory markers and to analyse whether these factors were related with the clinical outcome in HD patients. Methods: A cross-sectional study in 80 HD patients (men, 65%; aged 68.2 ± 14.2) was carried out. Abdominal fat deposition was evaluated by Ci median with regard to baseline inflammatory, anthropomorphic, and nutritional markers. Linear regression analysis was applied to identify whether serum C-reactive protein (CRP), as an inflammatory biomarker, was an independent predictor of Ci in HD patients. Results: Mean Ci was significantly greater in men (p = 0.001). Significant positive correlations were observed between Ci and serum triglycerides (r = 0.23; p < 0.05) and Ln of serum CRP (r = 0.27; p < 0.01). A significantly higher median Ci (men ≥ 1.39 and women ≥ 1.33) was observed in inflammated overweight patients by multivariate analysis (p < 0.05). Serum CRP, as an inflammatory biomarker, was a significant predictor (p = 0.021) of Ci, but its predictive value disappeared after median Ci adjustment of linear regression analysis. Conclusion: Abdominal fat mass, measured by Ci, appears directly linked to inflammation in dialysis. Results support the hypothesis that inflammation in HD patients has pleiotropic effects depending on abdominal body adiposity.
abstract_unstemmed	Introduction: Abdominal fat mass is an important risk factor of inflammation in the general population as it is in haemodialysis (HD) patients. The aim of this study was to investigate the association of adiposity using the conicity index (Ci) with nutritional-inflammatory markers and to analyse whether these factors were related with the clinical outcome in HD patients. Methods: A cross-sectional study in 80 HD patients (men, 65%; aged 68.2 ± 14.2) was carried out. Abdominal fat deposition was evaluated by Ci median with regard to baseline inflammatory, anthropomorphic, and nutritional markers. Linear regression analysis was applied to identify whether serum C-reactive protein (CRP), as an inflammatory biomarker, was an independent predictor of Ci in HD patients. Results: Mean Ci was significantly greater in men (p = 0.001). Significant positive correlations were observed between Ci and serum triglycerides (r = 0.23; p < 0.05) and Ln of serum CRP (r = 0.27; p < 0.01). A significantly higher median Ci (men ≥ 1.39 and women ≥ 1.33) was observed in inflammated overweight patients by multivariate analysis (p < 0.05). Serum CRP, as an inflammatory biomarker, was a significant predictor (p = 0.021) of Ci, but its predictive value disappeared after median Ci adjustment of linear regression analysis. Conclusion: Abdominal fat mass, measured by Ci, appears directly linked to inflammation in dialysis. Results support the hypothesis that inflammation in HD patients has pleiotropic effects depending on abdominal body adiposity.
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title_short	Conicity index as a contributor marker of inflammation in haemodialysis patients
url	https://doi.org/10.3305/nh.2013.28.5.6626 https://doaj.org/article/a3ce59b3c96545a5841c9df0062857da http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112013000500047&lng=en&tlng=en https://doaj.org/toc/0212-1611
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author2	Guillermina Barril Francisco J. Sánchez-Muniz
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up_date	2024-07-04T01:04:06.674Z
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Serum CRP, as an inflammatory biomarker, was a significant predictor (p = 0.021) of Ci, but its predictive value disappeared after median Ci adjustment of linear regression analysis. Conclusion: Abdominal fat mass, measured by Ci, appears directly linked to inflammation in dialysis. Results support the hypothesis that inflammation in HD patients has pleiotropic effects depending on abdominal body adiposity.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Índice de conicidad</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Grasa abdominal</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Inflamación</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Malnutrición-inflamación</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hemodiálisis</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Nutritional diseases. 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Conicity index as a contributor marker of inflammation in haemodialysis patients

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