The Yin and Yang of nicotine: harmful during development, beneficial in adult patient populations

Nicotine has remarkably diverse effects on the brain. Being the main active compound in tobacco, nicotine can aversively affect brain development. However, it has the ability to act positively by restoring attentional capabilities in smokers. Here, we focus on nicotine exposure during the prenatal a...
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Gespeichert in:

Autor*in:	Danielle S Counotte [verfasserIn] August B Smit [verfasserIn] Sabine eSpijker [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2012

Schlagwörter:	Nicotine Brain Development animal model ADHD nicotinic acetylcholine receptors Developmental stages

Übergeordnetes Werk:	In: Frontiers in Pharmacology - Frontiers Media S.A., 2010, 3(2012)
Übergeordnetes Werk:	volume:3 ; year:2012

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3389/fphar.2012.00180

Katalog-ID:	DOAJ013122339

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callnumber-first	R - Medicine
author	Danielle S Counotte
spellingShingle	Danielle S Counotte misc RM1-950 misc Nicotine misc Brain Development misc animal model misc ADHD misc nicotinic acetylcholine receptors misc Developmental stages misc Therapeutics. Pharmacology The Yin and Yang of nicotine: harmful during development, beneficial in adult patient populations
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topic_title	RM1-950 The Yin and Yang of nicotine: harmful during development, beneficial in adult patient populations Nicotine Brain Development animal model ADHD nicotinic acetylcholine receptors Developmental stages
topic	misc RM1-950 misc Nicotine misc Brain Development misc animal model misc ADHD misc nicotinic acetylcholine receptors misc Developmental stages misc Therapeutics. Pharmacology
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title	The Yin and Yang of nicotine: harmful during development, beneficial in adult patient populations
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title_sort	yin and yang of nicotine: harmful during development, beneficial in adult patient populations
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title_auth	The Yin and Yang of nicotine: harmful during development, beneficial in adult patient populations
abstract	Nicotine has remarkably diverse effects on the brain. Being the main active compound in tobacco, nicotine can aversively affect brain development. However, it has the ability to act positively by restoring attentional capabilities in smokers. Here, we focus on nicotine exposure during the prenatal and adolescent developmental periods and specifically, we will review the long-lasting effects of nicotine on attention, both in humans and animal models. We discuss the reciprocal relation of the beneficial effects of nicotine, improving attention in smokers and in patients with neuropsychiatric diseases, such as schizophrenia and attention deficit/hyperactivity disorder, versus nicotine-related attention deficits already caused during adolescence. Given the need for research on the mechanisms of nicotine’s cognitive actions, we discuss some of the recent work performed in animals.
abstractGer	Nicotine has remarkably diverse effects on the brain. Being the main active compound in tobacco, nicotine can aversively affect brain development. However, it has the ability to act positively by restoring attentional capabilities in smokers. Here, we focus on nicotine exposure during the prenatal and adolescent developmental periods and specifically, we will review the long-lasting effects of nicotine on attention, both in humans and animal models. We discuss the reciprocal relation of the beneficial effects of nicotine, improving attention in smokers and in patients with neuropsychiatric diseases, such as schizophrenia and attention deficit/hyperactivity disorder, versus nicotine-related attention deficits already caused during adolescence. Given the need for research on the mechanisms of nicotine’s cognitive actions, we discuss some of the recent work performed in animals.
abstract_unstemmed	Nicotine has remarkably diverse effects on the brain. Being the main active compound in tobacco, nicotine can aversively affect brain development. However, it has the ability to act positively by restoring attentional capabilities in smokers. Here, we focus on nicotine exposure during the prenatal and adolescent developmental periods and specifically, we will review the long-lasting effects of nicotine on attention, both in humans and animal models. We discuss the reciprocal relation of the beneficial effects of nicotine, improving attention in smokers and in patients with neuropsychiatric diseases, such as schizophrenia and attention deficit/hyperactivity disorder, versus nicotine-related attention deficits already caused during adolescence. Given the need for research on the mechanisms of nicotine’s cognitive actions, we discuss some of the recent work performed in animals.
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title_short	The Yin and Yang of nicotine: harmful during development, beneficial in adult patient populations
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